12 products were found matching "6584-1"!

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Anti-GCAT
Anti-GCAT

Item number: E-AB-66584.120

The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this...
Keywords: Anti-KBL, Anti-GCAT, Anti-AKB ligase, EC=2.3.1.29, Anti-Aminoacetone synthase, Anti-Glycine acetyltransferase,...
Application: WB, IHC, IF
Host: Rabbit
Species reactivity: human, mouse, rat
From 198.00€ *
Review
SR 16584
SR 16584

Item number: Cay10683-1

Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels in the central and peripheral nervous system. SR 16584 is an antagonist of the alpha3beta4 nAChR subtype (IC50 = 10.2 µM). It shows selective binding of the alpha3beta4 subtype compared to the alpha4beta2 and alpha7 subtypes (Ki values of...
Keywords: 3-dihydro-1-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-2H-indol-2-one
Application: alpha3beta4 nAChR antagonist
CAS 1150153-86-8
MW: 270.4 D
From 44.00€ *
Review
DC-05
DC-05

Item number: Cay36584-1

DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1, IC50 = 10.3 µM). It is selective for DNMT1 over DNMT3A and DNMT3B (IC50s = >200 µM), as well as the additional methyltransferases G9a, SUV39H1, MLL1, SET7/9, and PRMT1 (IC50s = >150, >150, >150, >150, and 37.1 µM, respectively). DC-05 (2.5-10 µM) reduces...
Keywords: alpha-[[[2-(1H-indol-3-yl)ethyl]amino]methyl]-9H-carbazole-9-ethanol
Application: Non-nucleoside DNMT1 inhibitor
CAS 890643-16-0
MW: 383.5 D
From 60.00€ *
Review
TSLP Mouse
TSLP Mouse

Item number: ABE-32-6584-1

Source: Sf9, Baculovirus cells.Sterile Filtered colorless solution.TSLP protein is a hemopoietic cytokine which signals throughout a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor & the Interleukin-7 receptor alpha chain. TSLP impacts myeloid cells thus induces the discharge of...
Expressed in: Insect cells
Origin: mouse
From 438.00€ *
Review
Thg1L, Mouse tRNA-histidine guanylyltransferase 1-like (S. cerevisiae), Real Time PCR Primer Set
Thg1L, Mouse tRNA-histidine guanylyltransferase 1-like...

Item number: VMPS-6584

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: Thg1l, EC=2.7.7.-, tRNA-histidine guanylyltransferase, Probable tRNA(His) guanylyltransferase
Application: RNA quantification
43.00€ *
Review
Anti-SLC25A12
Anti-SLC25A12

Item number: E-AB-63584.120

This gene encodes a calcium-binding mitochondrial carrier protein. The encoded protein localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane. Polymorphisms in this gene may be associated with autism, and mutations in this gene may also be a...
Keywords: Anti-ARALAR1, Anti-SLC25A12, Anti-Solute carrier family 25 member 12, Anti-Mitochondrial aspartate glutamate carrier 1,...
Application: WB
Host: Rabbit
Species reactivity: human, mouse, rat
From 198.00€ *
Review
Anti-CDKN3
Anti-CDKN3

Item number: E-AB-60584.120

The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or...
Keywords: Anti-CDI1, Anti-CDKN3, EC=3.1.3.16, EC=3.1.3.48, Anti-Kinase-associated phosphatase, Anti-Cyclin-dependent kinase...
Application: WB, IF
Host: Rabbit
Species reactivity: human, mouse
From 198.00€ *
Review
Anti-PHIP
Anti-PHIP

Item number: E-AB-61584.120

Protein function: Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti- apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and...
Keywords: Anti-PHIP, Anti-DCAF14, Anti-PH-interacting protein, Anti-WD repeat-containing protein 11, Anti-IRS-1 PH domain-binding...
Application: WB, IHC, IF
Host: Rabbit
Species reactivity: human, mouse
From 198.00€ *
Review
Anti-CAPN1
Anti-CAPN1

Item number: E-AB-65834.120

The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small,...
Keywords: Anti-CANPL1, Anti-muCANP, Anti-CANP 1, Anti-Calpain mu-type, Anti-Micromolar-calpain, Anti-Calpain-1 large subunit,...
Application: IHC
Host: Rabbit
Species reactivity: human, mouse
From 198.00€ *
Review
Anti-GMPR
Anti-GMPR

Item number: E-AB-65884.120

This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides. Protein function: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It...
Keywords: Anti-GMPR, Anti-GMPR 1, Anti-GMP reductase 1, Anti-Guanosine monophosphate reductase 1, Anti-Guanosine 5'-monophosphate...
Application: IHC
Host: Rabbit
Species reactivity: human, mouse
From 198.00€ *
Review
Anti-STAT1
Anti-STAT1

Item number: E-AB-65894.120

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This...
Keywords: Anti-STAT1, Anti-Transcription factor ISGF-3 components p91/p84, Anti-Signal transducer and activator of transcription...
Application: IF
Host: Rabbit
Species reactivity: human, mouse
From 198.00€ *
Review
Anti-CDK7
Anti-CDK7

Item number: E-AB-65984.120

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a...
Keywords: Anti-CAK, Anti-CDK7, Anti-p39 Mo15, EC=2.7.11.22, EC=2.7.11.23, Anti-39 kDa protein kinase, Anti-CDK-activating kinase 1,...
Application: IF
Host: Rabbit
Species reactivity: human
From 198.00€ *
Review