- Search results for Cay11070
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7 products were found matching "Cay11070"!
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Item number: Cay11070-100
Bromodomain-containing 2 (BRD2) is a transcriptional regulator that is a member of the bromodomain and extra-terminal (BET) family. It is ubiquitously expressed and localizes to the nucleus. BRD2 is composed of two N-terminal bromodomains (BD1 and BD2) that bind acetylated lysine on histones, serving to couple...
Keywords: | BRD2, O27.1.1, O27.1.1, KIAA9001, Bromodomain-containing protein 2, Bromodomain-containing protein 2, Really interesting... |
Expressed in: | E.coli |
MW: | 42,0 kD |
From 378.00€
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Item number: Cay18905-1
Prostaglandin E2 (PGE2, Cay-14010) is the major PG synthesized at sites of inflammation and plays an important role in different inflammatory diseases. It acts as a mediator of pain and inflammation and promotes bone destruction. The increased synthesis of PGE2 during inflammation can be accounted for by increased...
Keywords: | 2-chloro-5-[[(2,2-dimethyl-1-oxopropyl)amino]methyl]-N-1H-imidazol-2-yl-benzamide |
Application: | mPGES-1 inhibitor |
CAS | 1381846-21-4 |
MW: | 334.8 D |
From 77.00€
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Item number: Cay31216-250
CAY10770 is an inhibitor of the cytochrome P450 (CYP) isoform CYP4Z1 (IC50 = 5.9 µM). It is selective for CYP4Z1 over CYP4A11, CYP4F2, CYP4F3a, CYP4F3b (IC50s = 187-282 µM) but does inhibit CYP4F8 and CYP4F12 (IC50s = 167 and 91 µM, respectively). CAY10770 (3 µM) inhibits the production of 14(15)-EET, 19-HETE, and...
Keywords: | 8-(1H-benzotriazol-1-ylamino)-octanoic acid |
Application: | CYP4Z1 inhibitor |
CAS | 2428734-45-4 |
MW: | 276.3 D |
From 84.00€
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Item number: Cay10770-25
The DNA methyltransferase 3 (DNMT3) family of DNMT proteins establish intial methylation of cytosines to form 5-methylcytosine at CpG (cytosine-phosphate-guanine) sites. Once methylation is established on DNA, DNMT1 protein is responsible for maintaining the CpG methylation pattern during chromosome replication. The...
Keywords: | DNMT3L, DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3-like |
Application: | Methylation studies |
MW: | 53,2 kD |
732.00€
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Item number: Cay10070-100
15-epi Prostaglandin A1 (15-epi PGA1) is the 15(R) stereoisomer of PGA1. Prostaglandins of the A-series, including some with 15(R) stereochemistry, are natural products of gorgonian soft corals. PGA1 causes renal vasodilation, increased urine sodium excretion, and decreased arterial pressure in hypertensive...
Keywords: | 15-epi PGA1, 9-oxo-15R-hydroxy-prosta-10,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 20897-92-1 |
MW: | 336.5 D |
From 43.00€
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Item number: Cay11076-50
The Epigenetics Screening Library contains more than 140 small molecules that are known to modulate the activity of a variety of epigenetic 'writers and erasers' and 'reader' proteins in a 96-well Matrix tube rack format as 10 mM stocks in DMSO. It may include compounds that modulate the activity of...
Application: | Epigenetic studies |
1,779.00€
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Item number: Cay11075-10
JWH 018 is a synthetic cannabinoid (CB) that potently activates the central CB1 and peripheral CB2 receptors (Ki = 9.0 and 2.94 nM, respectively). This cannabimimetic compound has frequently been found in herbal blends. JWH 018 N-(4,5-epoxypentyl) analog is distinguished by a terminal epoxide group on the alkyl...
Keywords: | JWH 018 epoxide, naphthalen-1-yl(1-(3-(oxiran-2-yl)propyl)-1H-indol-3-yl)methanone |
Application: | Analytical reference standard, synthetic cannabinoid analog |
CAS | 2365471-31-2 |
MW: | 355.4 D |
From 109.00€
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