10 products were found matching "Cay90192"!
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HJC0197
Item number: Cay19092-1
Exchange protein activated by cAMP (Epac) proteins mediate cAMP signaling independent of protein kinase A (PKA). HJC0197 is a cell-permeable inhibitor of Epac1 and Epac2 (IC50 = 5.9 µM for Epac2). It inhibits Epac1-mediated Rap1-GDP exchange activity at 25 µM, but has no effect on cAMP-induced type I and II PKA...
| Keywords: | 4-cyclopentyl-2-[[(2,5-dimethylphenyl)methyl]thio]-1,6-dihydro-6-oxo-5-pyrimidinecarbonitrile |
| Application: | Cell-permeable Epac1 / Epac2 inhibitor |
| CAS | 1383539-73-8 |
| MW: | 339.5 D |
From 50.00€
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5-methoxy Methylone (hydrochloride)
Item number: Cay9002195-50
Methylone (Cay-10986) is a beta-ketone analog of 3,4-methylenedioxymethamphetamine (3,4-MDMA, Cay-13971) that has been detected in products marketed as bath salts, plant food, and tablets. Similar to 3,4-MDMA, it acts on components of the monoaminergic systems. 5-methoxy Methylone is a cathinone derivative that...
| Keywords: | 1-(7-methoxy-1,3-benzodioxol-5-yl)-2-(methylamino)-1-propanone, mononhydrochloride |
| Application: | Analytical reference material, Cathinone derivative |
| CAS | 2702151-27-5 |
| MW: | 273.7 D |
From 291.00€
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Alloxan (hydrate)
Item number: Cay9002196-5
Alloxan is a toxin that selectively eliminates pancreatic beta-cells in mice, rats, and certain other animals, and is used to model type 1 diabetes in humans. Reduction of alloxan within beta-cells precedes the generation of reactive oxygen species, which in turn contribute to beta-cell death. The dose of alloxan...
| Keywords: | 2,4,5,6(1H,3H)-pyrimidinetetrone, monohydrate |
| Application: | beta-cell elimination |
| CAS | 2244-11-3 |
| MW: | 160.1 D |
From 43.00€
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N-acetyl-3,4-Methylenedioxymethcathinone
Item number: Cay9001492-10
N-acetyl-3,4-Methylenedioxymethcathinone (N-acetyl-3,4-MDMC) is an acetylated analog of methylone (Cay-10986), the MDMA-type designer drug that has been detected in products marketed as bath salts, plant food, and tablets. The biological actions of N-acetyl-3,4-MDMC are unknown. This product is intended for forensic...
| Keywords: | N-acetyl Methylone, N-acetyl-3,4-MDMC, N-[2-(1,3-benzodioxol-5-yl)-1-methyl-2-oxoethyl]-N-methyl-acetamide |
| Application: | Analytical reference standard, Acetylated methylone analog |
| CAS | 1227293-15-3 |
| MW: | 249.3 D |
From 84.00€
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7-APDB (hydrochloride)
Item number: Cay9001892-5
7-APDB (hydrochloride) (Cay-9001892) is an analytical reference standard categorized as a benzofuran. This product is intended for research and forensic applications.Formal Name: 2,3-dihydro-alpha-methyl-7-benzofuranethanamine, monohydrochloride. Molecular Formula: C11H15NO . HCl. Formula Weight: 213.7. Purity:...
| Keywords: | 7-(2-Aminopropyl)-2,3-dihydrobenzofuran, 2,3-dihydro-alpha-methyl-7-benzofuranethanamine, monohydrochloride |
| Application: | Analytical reference standard, Benzofuran |
| MW: | 213.7 D |
From 291.00€
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AF3485
Item number: Cay9001962-1
Microsomal prostaglandin E synthase-1 (mPGES-1) converts the COX product PGH2 (Cay-17020) into the biologically active PGE2 (Cay-14010). Like COX-2, the expression of mPGES-1 is induced in response to pro-inflammatory mediators, including LPS, IL-1beta, and TNF-alpha. AF3485 is a selective 3-aminocarbazole inhibitor...
| Keywords: | CAY10686, N-[9-(2-hydroxyethyl)-9H-carbazol-3-yl]-2-(trifluoromethyl)-benzamide |
| Application: | mPGES-1 inhibitor |
| CAS | 1195786-61-8 |
| MW: | 398.4 D |
From 92.00€
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KDU691
Item number: Cay29019-5
KDU691 is an antimalarial compound. It inhibits recombinant P. vivax phosphatidylinositol 4-kinase (PI4K) with an IC50 value of 1.5 nM. KDU691 is selective for P. vivax PI4K over recombinant human PI4KbetaIII and PI3Kalpha, -beta, -?, and -delta (IC50s = 7.9, 8.8, 2.4, 8, and 3.4 µM, respectively), as well as VPS34...
| Keywords: | N-(4-chlorophenyl)-N-methyl-3-[4-[(methylamino)carbonyl]phenyl]-imidazo[1,2-a]pyrazine-6-carboxamide |
| Application: | Antimalarial compound |
| CAS | 1513879-19-0 |
| MW: | 419.9 D |
From 80.00€
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ON-123300
Item number: Cay19902-25
ON-123300 is a multi-kinase inhibitor. It inhibits ARK5, Cdk4, and Cdk6 (IC50s = 3.87, 9.82, and 4.95 nM, respectively) as well as FYN, PDGFRbeta, Abl, and PI3Kdelta (IC50s = 11.09, 26, 53.32, and 144 nM, respectively) among others. It inhibits proliferation in a panel of 38 cancer cell lines (GI50s = 0.05-5 µM)....
| Keywords: | 8-cyclopentyl-7,8-dihydro-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-7-oxo-pyrido[2,3-d]pyrimidine-6-carbonitrile |
| Application: | CDK inhibitor |
| CAS | 1357470-29-1 |
| MW: | 429.5 D |
From 50.00€
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4(S),11(R)-DiHDoHE
Item number: Cay9001290-100
Docosahexaenoic acid (DHA, Cay-90310) is an omega-3 fatty acid that is abundant in the brain and the retina and is known to be important in early development. Recently, various DHA metabolites, including 7(R)-Maresin 1 (Cay-10878) and 10(S),17(S)-DiHDoHE (Cay-10008128), have been shown to block infiltration of...
| Keywords: | 4S,11R-dihydroxydocosa-5Z,7E,9E,13Z,16Z,19Z-hexaenoic acid |
| Application: | Dihydroxy-DHA derivative |
| MW: | 360.5 D |
From 245.00€
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5(Z),8(Z),11(Z)-Eicosatrienoic Acid Ethanolamide
Item number: Cay90195-1
5(Z),8(Z),11(Z)-Eicosatrienoic acid ethanolamide is essentially identical to AEA in its agonist binding to CB1 and CB2 receptors. In L cells expressing the human CB1 receptor, the Ki value for 5(Z),8(Z),11(Z)-eicosatrienoic acid ethanolamide and AEA binding is 753 nM. In AtT-20 cells expressing the human CB2...
| Keywords: | Mead Acid Ethanolamide, N-(2-hydroxyethyl)-5Z,8Z,11Z-eicosatrienamide |
| Application: | CB receptor agonist |
| CAS | 169232-04-6 |
| MW: | 349.6 D |
From 66.00€
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