Anti-phospho-SMC1 (Ser957)

Anti-phospho-SMC1 (Ser957)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A300-045A-T 10 µl (10 µg) -

2 - 8 business days*

164.00€
A300-045A 100 µl (100 µg) -

2 - 8 business days*

626.00€
 
Protein function: Involved in chromosome cohesion during cell cycle and in DNA repair. Central... more
Product information "Anti-phospho-SMC1 (Ser957)"
Protein function: Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, or via its phosphorylation by ATR. Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint. [The UniProt Consortium]
Keywords: Anti-phospho-SMC1A, Anti-phospho-Sb1.8, Anti-phospho-SMC-1A, Anti-phospho-DXS423E, Anti-phospho-SMC-1-alpha, Anti-phospho-SMC protein 1A, Anti-phospho-Structural maintenance of chromosomes protein 1A
Supplier: Bethyl Laboratories
Supplier-Nr: A300-045A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: bovine)
Immunogen: synthetic phospho-peptide. Immunogen for A300-045A was a phosphorylated synthetic peptide, which represented a portion of human Structural Maintenance of Chromosomes 1 (GeneID 8243) around serine 957 according to the numbering given in entry NP_006297.2.
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-phospho-SMC1 (Ser957)"
Write a review
or to review a product.
Viewed