IL-10 (human): Fc (human) (rec.)

IL-10 (human): Fc (human) (rec.)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
CHI-HF-21010-C010 10 µg - -

3 - 9 business days*

264.00€
 
Unfortunately, most cytokines have short circulating half-lives. With the creation of a group of... more
Product information "IL-10 (human): Fc (human) (rec.)"
Unfortunately, most cytokines have short circulating half-lives. With the creation of a group of new immunoglobulin- based cytokine fusion proteins, in which a cytokine sequence had been genetically fused to the hinge, CH2 and CH3 regions of an immunoglobulin, these cytokine fusion proteins possess both the biological functions of the cytokine moiety and the prolonged circulating half-life determined by the Fc domain. Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells, and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T-cell mediated autoimmune diseases.
Keywords: IL10, CSIF, IL-10, Interleukin-10, Cytokine synthesis inhibitory factor
Supplier: Chimerigen Laboratories
Supplier-Nr: HF-21010

Properties

Application: Bioassays
Conjugate: No
Host: Hamster cells
Species reactivity: human
Purity: >98%
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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