Anti-FAS

Anti-FAS
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-858A-T 10 µl (10 µg) -

2 - 8 business days*

164.00€
A302-858A 100 µl (100 µg) -

2 - 8 business days*

588.00€
 
Protein function: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the... more
Product information "Anti-FAS"
Protein function: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). [The UniProt Consortium]
Keywords: Anti-FAS, Anti-APT1, Anti-CD95, Anti-Apo-1 antigen, Anti-FASLG receptor, Anti-Apoptosis-mediating surface antigen FAS, Anti-Tumor necrosis factor receptor superfamily member 6
Supplier: Bethyl Laboratories
Supplier-Nr: A302-858A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: chimpanzee, crab-eating macaque)
Immunogen: Synthetic peptide. The epitope recognized by A302-858A maps to a region between residue 285 and 335 of human Fas (TNF receptor superfamily, member 6) using the numbering given in entry NP_000034.1 (GeneID 355).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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