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IL-17A Prom-LUCPorter(TM) Cell Line

ART NR.: IML-301 (1 vial)

Hersteller: Imgenex


Anwendungen: Agonist / antagonist screening

Format: cells

Lagerung: N2°C

Versand: -80°C

UniProt ID: Q16552 | Suche mit UniProt ID

Gene ID: Gene ID 3605 | Suche mit Gene ID

KEGG ID: K05489 | Suche mit KEGG ID

Schlagworte: NBP2-26283, Il17a, IL-17, Ctla8, IL-17A, CTLA-8, Interleukin-17A, Cytotoxic T-lymphocyte-associated antigen 8


1 vial

Bemerkungen: IL-17A Prom/LUCPorter(TM) HEK293 is a stably transfected cell line which expresses SwitchGear's RenSP luciferase reporter gene under the transcriptional control of the IL-17A promoter. Induction of the IL-17A promoter by RORgammat has been demonstrated. RORgammat significantly mediated activation of the IL-17A promoter quantified by luciferase activity. This new cell line together with LightSwitch Lusiferase Assay Reagent (TM) (Catalog Nos. LS010 and LS100) from SwitchGear Genomics form a complete luciferase assay read-out system for studying the molecular signals and relative impact role of IL-17A in autoimmune models.

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