- Search results for Cay10011125
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14 products were found matching "Cay10011125"!
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Item number: Cay10011125-1
Low-density lipoproteins (LDL) is the major carrier of cholesterol in the blood, accounting for more than 60% of total plasma cholesterol. LDL is taken up by hepatic and extrahepatic tissues through LDL receptor-mediated endocytosis where it is internalized and degraded to free cholesterol and amino acids. Uptake of...
Keywords: | Low-Density Lipoprotein Uptake |
Application: | FC, fluorescence |
554.00€
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Item number: Cay11012-5
Delphinidin (chloride) is an anthocyanidin, a natural plant pigment which serves as the precursor of certain anthocyanins that provide the blue-red colors of flowers, fruits, and red wine. Delphinidin induces the release of nitric oxide by vascular endothelium, causing vasorelaxation. It also inhibits signaling...
Keywords: | Ephdine, 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-1-benzopyrylium, chloride |
Application: | Vasorelaxant |
CAS | 528-53-0 |
MW: | 338.7 D |
From 50.00€
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Item number: Cay10112-5
Diets high in fiber contain plant lignan species that may be directly responsible for some observed health benefits of these diets. Enterolactone is an enterobacterial breakdown product of plant lignans that is absorbed and can be measured in human serum. Enterolactone and other lignans and phytoestrogens have been...
Keywords: | HPMF, (±)-dihydro-(3,4)-bis[(3-hydroxyphenyl)methyl]-2(3H)-furanone |
Application: | Metabolic studies |
CAS | 78473-71-9 |
MW: | 298.3 D |
From 43.00€
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Item number: Cay10012555-1
Hydrogen sulfide (H2S) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. Sodium hydrogen sulfide is an H2S donor commonly used in cellular and whole animal experimental systems. For example, it has...
Keywords: | NaHS, NSC 158264, Sodium Hydrosulfide, sodium sulfide, hydrate |
Application: | Hydrogen sulfide donor |
CAS | 207683-19-0 |
MW: | 56.1 D |
From 31.00€
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Item number: Cay10011255-5
Casein Kinase 2 (CK2) is a serine/threonine-selective protein kinase involved in many signal transduction pathways. CK2 is known to negatively regulate apoptosis, and its activity is increased in many proliferating tissues and tumors, which lends promise as an anticancer drug target. NSC 210902 inhibits CK2 with an...
Keywords: | 1,4-dihydro-4-oxo-benzo[h]quinoline-3-carboxylic acid |
Application: | CK2 inhibitor |
CAS | 51726-83-1 |
MW: | 239.2 D |
From 44.00€
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Item number: Cay10011126-5
Clobenpropit is a selective histamine H3 receptor antagonist (Ki = 0.17 nM in rat cortical membranes). Clobenpropit (0.3, 0.1, and 3 nM) reduces inhibition of electrically induced contractions in isolated guinea pig ileum longitudinal muscle by the H3 receptor agonist (R)-alpha-methylhistamine (Cay-25601). It does...
Keywords: | VUF 9153, N-[(4-chlorophenyl)methyl]-carbamimidothioic acid, 3-(1H-imidazol-5-yl)propyl ester, dihydrobromide |
Application: | Histamine H3 receptor antagonist |
CAS | 145231-35-2 |
MW: | 470.7 D |
From 50.00€
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Item number: Cay10011127-5
Thioperamide (maleate) is a selective histamine H3 receptor antagonist that crosses the blood-brain barrier. This compound binds to rat cerebral cortical cells in vitro with a pKi value of 8.4 and inhibits histamine binding in vivo with an ED50 value of 1 mg/kg. At a dose of 5 mg/kg thioperamide (maleate) inhibits...
Keywords: | N-cyclohexyl-4-(1H-imidazol-5-yl)-1-piperidinecarbothioamide, 2Z-butenedioate |
Application: | Histamine H3 receptor antagonist |
CAS | 148440-81-7 |
MW: | 408.5 D |
From 20.00€
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Item number: Cay10011124-5
Ribonucleotide reductase, the rate-limiting enzyme for de novo DNA synthesis, is a common target for chemotherapy. Its increased activity in cancer cells is associated with malignant transformation and proliferation. Trimidox is a specific ribonucleotide reductase inhibitor that reduces levels of dGTP and dCTP in...
Keywords: | CF 233 (hydrochloride), N,3,4,5-tetrahydroxy-benzenecarboximidamide, monohydrochloride |
Application: | Ribonucleotide reductase inhibitor |
CAS | 95933-75-8 |
MW: | 220.6 D |
From 86.00€
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Item number: Cay10011132-25
Type 4 cyclic nucleotide phosphodiesterases (PDE4) isoforms selectively inactivate the second messenger cAMP by hydrolyzing the phosphodiester bond, producing AMP. (±)-Rolipram is a cell-permeable selective PDE4 inhibitor. Since PDE4 is abundant in leukocytes, (±)-rolipram inhibits inflammation by suppressing...
Keywords: | SB 95952, ZK 62711, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone |
Application: | PDE4 inhibitor |
CAS | 61413-54-5 |
MW: | 275.3 D |
From 39.00€
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Item number: Cay10011199-25
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators...
Keywords: | C8-HSL, OHL, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-octanamide |
Application: | Bioactive lipid assays |
CAS | 147852-84-4 |
MW: | 227.3 D |
From 60.00€
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Item number: Cay10011131-25
Soluble guanylate cyclase (sGC) is the primary cellular receptor for nitric oxide (NO). NO binds and activates a heme group in sGC, initiating the conversion of GTP to the second messenger cyclic GMP (cGMP). BAY 41-8543 is a heme-dependent stimulator of sGC, increasing the activity of recombinant sGC...
Keywords: | 2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(4-morpholinyl)-4,6-pyrimidinediamine |
Application: | SGC stimulator |
CAS | 256498-66-5 |
MW: | 420.4 D |
From 44.00€
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Item number: Cay10011198-25
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is involved in a promising field of study. The expression of specific target genes, such as transcriptional...
Keywords: | C7-HSL, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-heptanamide |
Application: | Bioactive lipid assays |
CAS | 177158-20-2 |
MW: | 213.3 D |
From 44.00€
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