- Search results for Cay10010374-%25
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4 products were found matching "Cay10010374-%25"!
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Item number: Cay10010372-25
GW 842166X is a cannabinoid 2 (CB2) receptor agonist. It increases intracellular calcium mobilization induced by the CB receptor agonist CP 55,940 (Cay-13241) in HEK cells co-expressing a chimeric Galphaq/05 protein and the human CB2 receptor (EC50 = 7.78 µM). GW 842166X is selective for CB2 over the CB1 receptor...
Keywords: | 2-[(2,4-dichlorophenyl)amino]-N-[(tetrahydro-2H-pyran-4-yl)methyl]-4-(trifluoromethyl)-5-pyrimidinecarboxamide |
Application: | CB2 receptor agonist |
CAS | 666260-75-9 |
MW: | 449.3 D |
From 30.00€
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Item number: Cay10010344-25
Simvastatin is a competitive inhibitor of HMG-CoA reductase (Ki = 0.12 nM). Simvastatin reduces plasma cholesterol levels in rats and dogs when administered at doses of 1.2 and 8 mg/kg, respectively. Simvastatin suppresses TNF-induced NF-kappaB activation (IC50 = ~13 µM) and potentiates apoptosis in human myeloid...
Keywords: | MK-733,... |
Application: | HMG-CoA reductase inhibitor |
CAS | 79902-63-9 |
MW: | 418.6 D |
From 43.00€
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Item number: Cay10010334-25
Fluvastatin is an inhibitor of HMG-CoA reductase (Ki = 0.3 nM for the rat enzyme). It also inhibits the human cytochrome P450 (CYP) isoform CYP2C9 (IC50 = 100 nM). Fluvastatin inhibits oxidized LDL-induced ferroptosis and reverses oxidized LDL-induced decreases in glutathione peroxidase 4 (GPX4) and system Xc-...
Keywords: | 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid |
Application: | HMG-CoA reductase inhibitor |
CAS | 93957-54-1 |
MW: | 411.5 D |
From 54.00€
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Item number: Cay10010314-25
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds that act as PTK blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor (EGF) receptor kinase block...
Keywords: | Tyrphostin 47, Tyrphostin AG-213, 2-cyano-3-(3,4-dihydroxyphenyl)-2E-propenethioamide |
Application: | EGF receptor kinase inhibitor |
CAS | 122520-86-9 |
MW: | 220.2 D |
From 77.00€
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