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Sorafenib
Sorafenib

Item number: Cay10009644-10

Sorafenib is a multi-kinase inhibitor that inhibits Raf-1 and B-RAF (IC50s = 6 and 22 µM, respectively), as well as the receptor tyrosine kinases VEGFR2, VEGFR3, PDGFRbeta, FLT3, and c-Kit (IC50s = 90, 15, 20, 57, and 58 nM, respectively). It is selective for these kinases over 12 other kinases, including ERK1,...
Keywords: BAY 43-9006, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide
Application: Kinase inhibitor
CAS 284461-73-0
MW: 464.8 D
From 43.00€ *
Review
Eicosapentaenoyl Ethanolamide
Eicosapentaenoyl Ethanolamide

Item number: Cay10964-5

Eicosapentaenoyl ethanolamide (EPEA) is an N-acylethanolamide that inhibits dietary-restriction-induced lifespan extension in wild type and TOR pathway mutant nematodes. Produced endogenously from eicosapentaenoic acid, EPEA serves as a metabolic signal that couples nutrient availability with growth and lifespan....
Keywords: EPEA, N-(2-hydroxyethyl)-5Z,8Z,11Z,14Z,17Z-eicosapentaenamide
Application: Bioactive Lipid Assays
CAS 109001-03-8
MW: 345.5 D
From 84.00€ *
Review