- Search results for Cay10009172-%25
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7 products were found matching "Cay10009172-%25"!
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Item number: Cay10009197-25
Flavopiridol is an orally bioavailable inhibitor of cyclin dependent kinases (IC50s = ~100, ~100, ~100, and 300 nM for Cdk1, Cdk2, Cdk4, and Cdk7, respectively). It also inhibits TEFb, a complex composed of Cdk9 and cyclin T1, with a Ki value of 3 nM. Flavopiridol inhibits transcription of a CMV promoter in HeLa...
Keywords: | Alvocidib, HL 275, HMR 1275, L-868,275,... |
CAS | 131740-09-5 |
MW: | 438.3 D |
From 66.00€
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Item number: Cay10009152-25
Valinomycin is a cyclododecadepsipeptide potassium-selective ionophore antibiotic that is isolated from various strains of Streptomyces. The hydrophilic interior is the right size to accommodate the potassium ion, but not other ions, while the hydrophobic exterior allows the complex to pass through the lipid...
Keywords: | NSC 122023,... |
Application: | Antibiotic |
CAS | 2001-95-8 |
MW: | 1111.3 D |
From 34.00€
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Item number: Cay10009162-25
The effects of prostaglandin E2 (PGE2) are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4. GW 627368X is a potent and selective competitive antagonist of the EP4 receptor with additional human TP receptor affinity. In competition radioligand bioassays, GW 627368X had affinity for...
Keywords: | 4-(4,9-diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)-benzeneacetamide |
Application: | EP4 receptor antagonist |
CAS | 439288-66-1 |
MW: | 544.6 D |
From 80.00€
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Item number: Cay10006197-25
Leukotriene A4-d5 (LTA4-d5) methyl ester contains four deuterium atoms at the 19, 19', 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of LTA4 methyl ester by GC- or LC-mass spectrometry. LTA4 is synthesized in mast cells, eosinophils, and neutrophils from arachidonic...
Keywords: | LTA4-d5 methyl ester, 5S-trans-5,6-oxido-7E,9E,11Z,14Z-eicosatetraenoic-19,19,20,20, and 20-d5 acid, methyl ester |
Application: | Standard |
MW: | 337.5 D |
From 390.00€
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Item number: Cay10009317-25
Apoptosis can be induced when procaspase-3 is activated and converted to caspase-3. Procaspase-activating compound 1 (PAC-1) is a procaspase-3 activator and a potential drug treatment in cancer cell lines with elevated levels of procaspase-3. PAC-1's effectiveness was found to be directly proportional to the...
Keywords: | Procaspase-activating Compound 1, 4-(phenylmethyl)-1-piperazineacetic acid,... |
Application: | Procaspase-3 activator |
CAS | 315183-21-2 |
MW: | 392.5 D |
From 145.00€
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Item number: Cay10009817-25
Pleckstrin homology (PH) domains all contain a seven-standard beta-sandwich that allows binding to various species of phosphatidyl inositol (PtdIns) phosphates. Most PH domains bind to PtdIns phosphates with weak affinity and low specificity. However, a small subclass binds specifically and with high-affinity for...
Keywords: | Grp1, Grp1, ARNO3, Cytohesin-3, Cytohesin-3, Protein ARNO3, Protein ARNO3, ARF nucleotide-binding site opener 3, ARF... |
Application: | WB |
MW: | 41,7 kD |
From 189.00€
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Item number: Cay10007912-25
20-carboxy Arachidonic acid (20-COOH-AA) is the major metabolite of 20-HETE that is produced in renal tubular epithelial, endothelial, and microvascular smooth muscle cell cultures. This omega-oxidation conversion can take place using purified alcohol dehydrogenases three and four or by microsomes containing...
Keywords: | 20-carboxy AA, 20-COOH-AA, 5Z,8Z,11Z,14Z-eicosatetraenedioic acid |
Application: | Bioactive lipid assays |
CAS | 79551-84-1 |
MW: | 334.5 D |
From 300.00€
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