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Item number: Cay10008822-25

Bortezomib is a dipeptide boronic acid derivative that reversibly inhibits the 20S proteasome (Ki = 0.6 nM). It binds the beta5-subunit of the 20S proteasome and selectively inhibits chymotryptic activity. In part by blocking the degradation of tumor-suppressing and proapoptotic proteins, bortezomib drives cell...

Keywords:	LDP-341, MG-341, MLN341, NSC 681239, PS-341,...
Application:	Proteasome subunit beta type-1/5 inhibitor
CAS	179324-69-7
MW:	384.2 D

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