17-AAG (17-allylamino-17-demethoxygeldanamycin, Telatinib, Tanespimycin, NSC-330507, CNF-101, KOS-95

Semi-synthetic derivative of geldanamycin, demonstrating greater stability and lower in vivo toxicity than its parent compound. 17-AAG binds specifically to heat shock protein Hsp90 in a manner similar to geldanamycin, but the binding is weaker. Solubility: Soluble in DMSO at 150mg/ml, soluble in ethanol at 5mg/ml, very poorly soluble in water, maximum solubility in plain water is estimated to be about 20-50uM, buffers, serum, or other additives may increase or decrease the aqueous solubility. Melting Point: As Reported, Elemental Analysis: As Reported, Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. .