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128.078 Treffer print
ART-NR PRODUKT HERSTELLER MENGE PREIS
A0903-10.200
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WB, IHC, FC Erklärungen der Abkürzungen ansehen.
Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide selected from the C-terminal region of human ALAD (KLH).
USBio
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200 µl

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521 €


A2298-74W.100
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Rabbit SR: human, mouse, rat
Immunogen: Synthetic peptide corresponding to the N-terminal of human ATG3 protein conjugated to Blue Carrier Protein.
USBio
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100 µl

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578 €


C2442-32L.100
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Rabbit IgG SR: human, mouse, rat
Immunogen: Synthetic peptide corresponding to residues surrounding aa32 of mouse Fas.
USBio
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100 µg

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456 €


C5069-52.100 Chorionic Gonadotropin, Human, alpha (hCGa), Purified USBio
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100 µg

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399 €


C7510-11.10 Collagen Type I, Bovine (FITC)
Collagenase substrate Erklärungen der Abkürzungen ansehen.
USBio
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10 mg

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451 €


C8475-15.1 gamma-​Cyclodextrin (Cycloheptaamylose)
CAS: 17465-​86-​0
Molecular Formula: C48H80O40 . Mw: 1297,15.

MW: 1.297 D
Formula: C48H80O40
USBio
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1 g

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140 €


C9100-18.100
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Mouse IgG2a SR: human
USBio
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100 µg

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436 €


E3550-03A.1
ELISA Erklärungen der Abkürzungen ansehen.
Purity: Purified by Protein A chr
Mouse IgG2a kappa SR: human
Immunogen: Estradiol-6-CMO-BSA.
USBio
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1 mg

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504 €


H1840-10.100
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Rabbit
USBio
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100 µg

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168 €


M2200.1 Manganese Sulfate Monohydrate (Manganous Sulfate Monohydrate)
CAS: 10034-​96-​5
Molecular Formula: MnSO4.H2O. Mw: 169,02.

MW: 169 D
Formula: MnSO4.H2O
USBio
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1 kg

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56 €


M4615.500 MOPS Sodium Salt (Morpholinopropanesulfonic acid sodium salt)
CAS: 71119-​22-​7
Molecular Formula: C7H14NO4SNa. Mw: 231,2.

MW: 231 D
Formula: C7H14NO4S.Na
USBio
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500 g

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205 €


N2169-30.100
IHC, ICC, IF Erklärungen der Abkürzungen ansehen.
Rabbit SR: human, mouse, rat
USBio
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100 µg

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614 €


P9563.100
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Rabbit SR: rabbit
USBio
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100 µg

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588 €


029572.10
Protein function: Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis, the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA- Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]
USBio
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10 µg

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781 €

030519.100
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Protein function: Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis, the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA- Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Mouse IgG1 SR: human
Immunogen: Recombinant protein corresponding to a fragment of human p53, expressed in E. coli (Gene ID 7157).
USBio
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100 µl

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454 €

134615.50
WB, IF Erklärungen der Abkürzungen ansehen.
Purity: Purified by Protein A aff
Mouse IgG SR: human
Immunogen: Full length human TP53, aa1-393 (NP_000537).
USBio
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50 µg

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543 €

134616.100
WB, IP Erklärungen der Abkürzungen ansehen.
Purity: Serum
Rabbit IgG SR: human
Immunogen: Full length human TP53, aa1-393 (NP_000537.2).
USBio
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100 µl

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583 €

134617.100
WB Erklärungen der Abkürzungen ansehen.
Purity: Purified by Protein A aff
Rabbit IgG SR: human
Immunogen: Full length human TP53, aa1-393 (NP_000537.2).
USBio
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100 µg

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583 €

134618.100
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Purity: Purified by Protein A aff
Mouse IgG1 kappa SR: human
Immunogen: Partial recombinant corresponding to aa94-201 from human TP53 (AAH03596) with GST tag. MW of the GST tag alone is 26kD.
USBio
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100 µg

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543 €

136310.50
ELISA, IHC, IF Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to 379aa from human 53/p53.
USBio
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50 µg

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642 €

136486.50
ELISA, WB, IHC, IF Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to human TP53/p53 at C-Terminal.
USBio
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50 µg

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642 €

136487.50
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human, rat
Immunogen: Synthetic peptide corresponding to human TP53/p53 at N-Terminal.
USBio
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50 µg

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642 €

136488.50
ELISA, WB, IHC, IF Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human, mouse, rat
Immunogen: Synthetic peptide corresponding to human TP53/p53 at N-Terminal.
USBio
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50 µg

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642 €

138581.100
WB, IP, IHC Erklärungen der Abkürzungen ansehen.
Mouse IgG2b kappa SR: human
Immunogen: Recombinant protein fragment corresponding to human p53.
USBio
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100 µl

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271 €

138581.500
WB, IP, IHC Erklärungen der Abkürzungen ansehen.
Mouse IgG2b kappa SR: human
Immunogen: Recombinant protein fragment corresponding to human p53.
USBio
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500 µl

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411 €

P1001-26A.500
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WB, IP, FC Erklärungen der Abkürzungen ansehen.
Mouse IgG1 SR: human
USBio
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500 µl

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413 €

P1001-26A1.100
FC Erklärungen der Abkürzungen ansehen.
Mouse IgG2a SR: bovine, horse, cat, human
USBio
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100 µg

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566 €

P1001-26A4.100
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WB, IP, IHC Erklärungen der Abkürzungen ansehen.
Mouse IgG1 SR: human
USBio
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100 µg

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745 €

P1001-26A5.100
FC Erklärungen der Abkürzungen ansehen.
Mouse IgG2a SR: bovine, horse, cat, human
USBio
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100 tests

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595 €

P1001-26A6.100
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WB, Gel Erklärungen der Abkürzungen ansehen.
Rabbit SR: human, monkey
USBio
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100 µl

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576 €

P1001-26A8.100
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WB, IHC Erklärungen der Abkürzungen ansehen.
Mouse IgG2a SR: human
Immunogen: Human p53
USBio
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100 µg

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755 €

P1001-26AX.100
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WB, IP, FC Erklärungen der Abkürzungen ansehen.
Mouse IgG1 SR: human
USBio
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100 µl

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607 €

P1001-26B2.100
WB Erklärungen der Abkürzungen ansehen.
Purity: Purified by immunoaffinit
Rabbit IgG SR: human
Immunogen: Synthesized non-phosphopeptide derived from human p53 around the phosphorylation site of serine 9 (D-P-SP-V-E).
USBio
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100 µg

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372 €

P1001-26D1.100
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WB, IP, IHC, ICC Erklärungen der Abkürzungen ansehen.
Mouse kappa kappa SR: human, mammalian, mouse, rat
USBio
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100 µg

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534 €

P1001-26D2.100
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WB, IP, IHC Erklärungen der Abkürzungen ansehen.
Mouse IgG1 SR: human
USBio
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100 µg

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344 €

P1001-26E.500
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WB, IP, IHC Erklärungen der Abkürzungen ansehen.
Mouse IgG2b SR: human
USBio
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500 µl

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523 €

P1001-26EX.100
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WB, IP, IHC Erklärungen der Abkürzungen ansehen.
Mouse IgG2b SR: human
USBio
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100 µl

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566 €

P1001-26F.500
IHC Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Recombinant protein corresponding to full length human wild type p53 protein.
USBio
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500 µl

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551 €

P1001-26G.100
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WB, IP, IHC, FC Erklärungen der Abkürzungen ansehen.
Mouse IgG2b SR: human
USBio
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100 µg

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556 €

P1001-26H.100
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WB, IP, IHC Erklärungen der Abkürzungen ansehen.
Mouse IgG1 SR: human
USBio
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100 µg

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566 €

P1001-26I.250
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Sheep SR: human, mouse, rat
USBio
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250 µg

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498 €

P1001-26J.100
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Mouse IgG1 SR: human
USBio
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100 µg

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566 €

P1001-26K.100
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ELISA, WB, IP, IHC, ICC Erklärungen der Abkürzungen ansehen.
Mouse IgG2a SR: human, monkey
Immunogen: Recombinant human wild-type p53 protein.
USBio
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100 µg

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575 €

P1001-26K1.100
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WB, IHC, FC Erklärungen der Abkürzungen ansehen.
Mouse IgG1 kappa SR: human
Immunogen: Recombinant human p53 protein.
USBio
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100 µg

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519 €

P1001-26L.100
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WB, IP, IHC Erklärungen der Abkürzungen ansehen.
Mouse IgG1 SR: human
USBio
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100 µg

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566 €

P1001-26M.100
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WB, IP, IHC Erklärungen der Abkürzungen ansehen.
Mouse IgG2a SR: human
USBio
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100 µg

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566 €

P1001-26N.100
WB, IHC, FC Erklärungen der Abkürzungen ansehen.
Mouse IgG1 kappa SR: human
Immunogen: Murine p53 fragment expressed in E. coli
USBio
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100 µg

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427 €

P1001-26N1.100
WB, IHC, FC Erklärungen der Abkürzungen ansehen.
Mouse IgG1 kappa SR: human
Immunogen: Murine p53 fragment expressed in E. coli
USBio
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100 µg

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442 €

P1001-26N2.120
WB, IHC, FC Erklärungen der Abkürzungen ansehen.
Mouse IgG1 kappa SR: human
Immunogen: Murine p53 expressed in E. coli
USBio
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120 tests

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481 €

P1001-26N3.120
WB, IHC, FC Erklärungen der Abkürzungen ansehen.
Mouse IgG1 kappa SR: human
Immunogen: Murine p53 expressed in E. coli
USBio
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120 tests

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543 €

P1001-26N4.1
WB, IHC Erklärungen der Abkürzungen ansehen.
Mouse IgG2b SR: human
Immunogen: Recombinant human wild type p53 protein.
USBio
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1 ml

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923 €

P1001-26N5.100
ELISA, WB Erklärungen der Abkürzungen ansehen.
Purity: Purified by immunoaffinit
Mouse IgG2b SR: human
Immunogen: P53 N-terminal linear epitope aa20-25.
USBio
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100 µg

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415 €

P1001-26N5.25
ELISA, WB Erklärungen der Abkürzungen ansehen.
Purity: Purified by immunoaffinit
Mouse IgG2b SR: human
Immunogen: P53 N-terminal linear epitope aa20-25.
USBio
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25 µg

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299 €

P1001-26R.100
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Mouse IgG2a SR: bovine, horse, cat, human
USBio
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100 µg

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466 €

P1001-26T.1
WB, IHC Erklärungen der Abkürzungen ansehen.
Mouse IgG2a SR: bovine, human
Immunogen: Human recombinant wild type p53 protein.
USBio
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1 ml

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900 €

P1001-26T1.100
WB, IP Erklärungen der Abkürzungen ansehen.
Purity: Purified by immunoaffinit
Mouse IgG2a SR: human
Immunogen: P53 N-terminal linear epitope aa20-25.
USBio
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100 µg

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415 €

P1001-26T1.25
WB, IP Erklärungen der Abkürzungen ansehen.
Purity: Purified by immunoaffinit
Mouse IgG2a SR: human
Immunogen: P53 N-terminal linear epitope aa20-25.
USBio
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25 µg

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299 €

P1001-26U.100
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WB, IP Erklärungen der Abkürzungen ansehen.
Mouse IgG1 SR: human
USBio
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100 µg

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566 €

P1001-26U1.100
FC Erklärungen der Abkürzungen ansehen.
Mouse IgG2a SR: human
Immunogen: Recombinant human p53
USBio
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100 µg

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556 €

P1001-26Y.1
IHC Erklärungen der Abkürzungen ansehen.
Rabbit SR: human
USBio
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1 ml

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1263 €

P1001-26Z.50
ELISA, WB, IP, IHC Erklärungen der Abkürzungen ansehen.
Mouse IgG2a kappa SR: human
Immunogen: Recombinant corresponding to human TP53.
USBio
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50 µg

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601 €

P1001-27.100
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ELISA, WB, IP Erklärungen der Abkürzungen ansehen.
MW: 53
Mouse IgG1 SR: human, monkey, mouse, rat
USBio
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100 µl

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479 €

P1001-27A.100
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MW: 53 kD
Rabbit SR: human, monkey, rat
USBio
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100 µl

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479 €

P1001-27B.100
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MW: 53 kD
Rabbit SR: human
USBio
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100 µl

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528 €

P1001-27B1.25
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide (LMLpSPDD) corresponding to human p53 at the phosphorylated site of Serine 46.
USBio
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25 µg

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411 €

P1001-27C.100
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ELISA, WB Erklärungen der Abkürzungen ansehen.
MW: 53 kD
Rabbit SR: human, mouse
USBio
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100 µl

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528 €

P1001-27C1.10
ELISA, WB, ICC Erklärungen der Abkürzungen ansehen.
Protein function: Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis, the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA- Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human, mouse, rat
Immunogen: Phosphopeptide corresponding to a region of the mouse p53 protein surrounding serine 389. Sequence is conserved in rat.
USBio
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10 blots

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588 €

P1001-27C2.25
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide (EGPDpSD) corresponding to human p53 at the phosphorylated site of Serine 392.
USBio
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25 µg

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411 €

P1001-27D.100
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ELISA, WB, IP Erklärungen der Abkürzungen ansehen.
MW: 53 kD
Rabbit SR: human, monkey, mouse, rat
USBio
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100 µl

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528 €

P1001-27D3.100
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WB, IP, ICC, FC Erklärungen der Abkürzungen ansehen.
Rabbit SR: human
Immunogen: synthetic peptide
USBio
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100 µl

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537 €

P1001-27D4.500
FC, IF Erklärungen der Abkürzungen ansehen.
Mouse IgG SR: human
Immunogen: Synthetic phosphopeptide (KLH-coupled) corresponding to residues surrounding Ser15 of human p53. Conjugated to Alexa Fluor? 488 under optimal conditions with an F/P ratio of 2-6.
USBio
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500 µl

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509 €

P1001-27D5.25
WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to human p53, phosphorylated at serine 15 (PPLpSQET).
USBio
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25 µg

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411 €

P1001-27E.100
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ELISA, WB, IP, ICC Erklärungen der Abkürzungen ansehen.
MW: 53 kD
Rabbit SR: hamster, human, monkey, mouse
USBio
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100 µl

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528 €

P1001-27E5.100
related products

WB, IP, IHC, ICC Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding the area encompassing and including phosphorylated Ser of human p53. Cellular Localization: Cytoplasm. Nucleus. Endoplasmic reticulum.
USBio
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100 µl

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641 €

P1001-27E6.25
WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide (MEEPQpSDPSVEP-NH2) corresponding to human p53 at the phosphorylated site of Serine 6.
USBio
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25 µg

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411 €

P1001-27F.100
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ELISA, WB, ICC, FC, IF Erklärungen der Abkürzungen ansehen.
MW: 53
Mouse IgG1 SR: human
USBio
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100 µl

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527 €

P1001-27G.100
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ELISA, WB Erklärungen der Abkürzungen ansehen.
MW: 53 kD
Rabbit SR: human, mouse
USBio
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100 µl

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528 €

P1001-27G2.25
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide (ETFpSDLW) corresponding to human p53 at the phosphorylated site of Serine 20.
USBio
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25 µg

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411 €

P1001-27H.100
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ELISA, WB, IP, ICC Erklärungen der Abkürzungen ansehen.
MW: 53 kD
Rabbit SR: human, monkey, mouse
USBio
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100 µl

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528 €

P1001-27H4.25
WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide (SDPpSVEP) corresponding to human p53 at the phosphorylated site of Serine 9.
USBio
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25 µg

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411 €

P1001-27J.100
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ELISA, WB, IP, ICC Erklärungen der Abkürzungen ansehen.
MW: 53 kD
Rabbit SR: human, monkey
USBio
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100 µl

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528 €

P1001-27J2.25
Gel Erklärungen der Abkürzungen ansehen.
Rabbit SR: human
Immunogen: Synthetic phosphopeptide (PLPpSQAM) corresponding to human p53 at the phosphorylated site of Serine 20.
USBio
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25 µg

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411 €

P1001-27K1-AP.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser20 of human p53 (KLH).
USBio
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200 µl

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637 €

P1001-27K1-APC.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser20 of human p53 (KLH).
USBio
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200 µl

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637 €

P1001-27K1-FITC.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser20 of human p53 (KLH).
USBio
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200 µl

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637 €

P1001-27K1-HRP.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser20 of human p53 (KLH).
USBio
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200 µl

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637 €

P1001-27K1-PE.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser20 of human p53 (KLH).
USBio
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200 µl

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637 €

P1001-27K1.200
related products

ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding S20 of human p53 (KLH).
USBio
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200 µl

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520 €

P1001-27K2-AP.200
ELISA, WB, IHC, Gel Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser315 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

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637 €

P1001-27K2-APC.200
ELISA, WB, IHC, Gel Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser315 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

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637 €

P1001-27K2-FITC.200
ELISA, WB, IHC, Gel Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser315 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

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637 €

P1001-27K2-HRP.200
ELISA, WB, IHC, Gel Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser315 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

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637 €

P1001-27K2-PE.200
ELISA, WB, IHC, Gel Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser315 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

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637 €

P1001-27K2.200
related products

ELISA, WB, IHC, Gel Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding S315 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

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521 €

P1001-27L-AP.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser376 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

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637 €

P1001-27L-APC.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser376 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

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637 €

P1001-27L-Biotin.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser376 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27L-FITC.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser376 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27L-HRP.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser376 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27L-PE.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser376 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

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637 €

P1001-27L.200
related products

ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding S376 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

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520 €

P1001-27L3-AP.200
ELISA, WB, IHC, Gel Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human, mouse
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Thr18 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

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637 €

P1001-27L3-APC.200
ELISA, WB, IHC, Gel Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human, mouse
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Thr18 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

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637 €

P1001-27L3-FITC.200
ELISA, WB, IHC, Gel Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human, mouse
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Thr18 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

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637 €

P1001-27L3-HRP.200
ELISA, WB, IHC, Gel Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human, mouse
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Thr18 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27L3-PE.200
ELISA, WB, IHC, Gel Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human, mouse
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Thr18 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

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637 €

P1001-27L3.200
related products

ELISA, WB, IHC, Gel Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human, mouse
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding T18 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

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520 €

P1001-27L5-AP.200
ELISA, Gel Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Thr55 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

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637 €

P1001-27L5-APC.200
ELISA, Gel Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Thr55 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27L5-FITC.200
ELISA, Gel Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Thr55 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27L5-HRP.200
ELISA, Gel Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Thr55 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27L5-PE.200
ELISA, Gel Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Thr55 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27L5.200
ELISA, Gel Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding T55 of human p53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

521 €

P1001-27L6-AP.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide selected from the C-terminal region of human p53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27L6-APC.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide selected from the C-terminal region of human p53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27L6-FITC.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide selected from the C-terminal region of human p53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27L6-HRP.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide selected from the C-terminal region of human p53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27L6-PE.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide selected from the C-terminal region of human p53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27L6.200
related products

ELISA, WB Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide selected from the C-terminal region of human p53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

521 €

P1001-27M-AP.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding T55 of human TP53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27M-APC.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding T55 of human TP53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27M-Biotin.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding T55 of human TP53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27M-FITC.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding T55 of human TP53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27M-HRP.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding T55 of human TP53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27M-PE.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding T55 of human TP53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27M.200
related products

ELISA, WB Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding T55 of human TP53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

520 €

P1001-27M1-AP.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding S15 of human TP53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27M1-APC.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding S15 of human TP53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27M1-FITC.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding S15 of human TP53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27M1-HRP.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding S15 of human TP53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27M1-PE.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding S15 of human TP53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27M1.200
related products

ELISA, WB Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding S15 of human TP53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

520 €

P1001-27M4-AP.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding S315 of human TP53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27M4-APC.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding S315 of human TP53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27M4-FITC.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding S315 of human TP53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27M4-HRP.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding S315 of human TP53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27M4-PE.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding S315 of human TP53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

P1001-27M4.200
related products

ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding S315 of human TP53 (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

520 €

P1001-27R.100
related products

WB, IP, IHC, ICC Erklärungen der Abkürzungen ansehen.
Rabbit SR: human, rat
Immunogen: synthetic peptide
USBio
Icon Datasheet
100 µl

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537 €

P1001-27S.100
related products

WB, IP, IHC, ICC Erklärungen der Abkürzungen ansehen.
Rabbit SR: human, rat
Immunogen: synthetic peptide
USBio
Icon Datasheet
100 µl

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586 €

P1001-27T1.1
WB, IHC, FC Erklärungen der Abkürzungen ansehen.
Mouse IgG1 SR: human
Immunogen: Human p53 beta galactosidase fusion.
USBio
Icon Datasheet
1 ml

Buy Bulk

923 €

P1001-27U.100
related products

WB, IHC Erklärungen der Abkürzungen ansehen.
Mouse IgG1 SR: human, mouse
Immunogen: Phosphorylated synthetic peptide: HKKLMFKTEGPDSD, representing the C-terminus of the human protein (residues 380-393), of Human p53.
USBio
Icon Datasheet
100 µg

Buy Bulk

596 €

P1001-27V.50
WB, Gel Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human, mouse, rat
Immunogen: Synthetic peptide (KKGQSTS) corresponding to human p53 at C-terminal.
USBio
Icon Datasheet
50 µg

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411 €

P1001-27W.50
WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide (MEEPQSDPSVEP) corresponding to N-terminus of human p53.
USBio
Icon Datasheet
50 µg

Buy Bulk

454 €

P1001-27W1.50
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human, monkey
Immunogen: Synthetic peptide corresponding to aa surrounding Serine 46 of human p53.
USBio
Icon Datasheet
50 µg

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454 €

P1001-27W2.50
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide (MEEPQSDPSVEP) corresponding to N-terminus of human p53.
USBio
Icon Datasheet
50 µg

Buy Bulk

454 €

P1001-27W3.50
WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide (MEEPQSDPSVEP) corresponding to N-terminus of human p53.
USBio
Icon Datasheet
50 µg

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548 €

P1001-27W4.1
WB, IHC Erklärungen der Abkürzungen ansehen.
Mouse IgG2,a SR: human
Immunogen: Recombinant human wild-type p53 protein.
USBio
Icon Datasheet
1 ml

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845 €

P1001-27X.50
WB, Gel Erklärungen der Abkürzungen ansehen.
Rabbit SR: human, monkey
Immunogen: Synthetic peptide (ETFSDLW) corresponding to aa surrounding Serine 20 of human p53.
USBio
Icon Datasheet
50 µg

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454 €

P1001-27Y.50
WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human, monkey
Immunogen: Synthetic peptide (PLPSQAM) corresponding to aa surrounding Serine 37 of human p53.
USBio
Icon Datasheet
50 µg

Buy Bulk

454 €

P1001-27Z.50
WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human, monkey
Immunogen: Synthetic peptide (EGPDSD) corresponding to aa surrounding Serine 392 of human p53.
USBio
Icon Datasheet
50 µg

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454 €

P1001-28.100
related products

WB, ICC Erklärungen der Abkürzungen ansehen.
Rabbit SR: human
USBio
Icon Datasheet
100 µl

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528 €

P1001-28A.100
related products

ELISA, WB, IP, IHC, ICC Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Purity: Supernatant
Rabbit IgG SR: human, mouse, rat
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding serine 46 of human p53 protein.
USBio
Icon Datasheet
100 µl

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586 €

P1001-28B.100
related products

WB, ICC Erklärungen der Abkürzungen ansehen.
Purity: Supernatant
Rabbit IgG SR: human
Immunogen: A phospho specific peptide corresponding to residues surrounding serine 33 of human p53.
USBio
Icon Datasheet
100 µl

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537 €

P1001-28C.200
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Rabbit SR: human
Immunogen: KLH-conjugated, synthetic peptide corresponding to aa367-379 of human p53 (SHLKSK[AcK]GQSTSR, where AcK denotes acetyllysine).
USBio
Icon Datasheet
200 µl

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512 €

P1001-28E.1
ELISA, IP, IHC, FC, IF Erklärungen der Abkürzungen ansehen.
Mouse SR: human
USBio
Icon Datasheet
1 mg

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1322 €

P1001-28E.100
ELISA, IP, IHC, FC, IF Erklärungen der Abkürzungen ansehen.
Mouse SR: human
USBio
Icon Datasheet
100 µg

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436 €

P1001-28E.500
ELISA, IP, IHC, FC, IF Erklärungen der Abkürzungen ansehen.
Mouse SR: human
USBio
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500 µg

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731 €

P1001-28F.25
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Mouse SR: human
USBio
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25 µg

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582 €

P1001-28G.250
IHC, ICC, IF Erklärungen der Abkürzungen ansehen.
Rabbit SR: human
USBio
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250 µl

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663 €

P1001-28H-AP.100
ELISA, WB, IHC, IF Erklärungen der Abkürzungen ansehen.
Mouse IgG1 SR: human
Immunogen: Recombinant protein corresponding to aa94-202 of human TP53.
USBio
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100 µl

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789 €

P1001-28H-APC.100
ELISA, WB, IHC, IF Erklärungen der Abkürzungen ansehen.
Mouse IgG1 SR: human
Immunogen: Recombinant protein corresponding to aa94-202 of human TP53.
USBio
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100 µl

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789 €

P1001-28H-Biotin.100
ELISA, WB, IHC, IF Erklärungen der Abkürzungen ansehen.
Mouse IgG1 SR: human
Immunogen: Recombinant protein corresponding to aa94-202 of human TP53.
USBio
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100 µl

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789 €

P1001-28H-FITC.100
ELISA, WB, IHC, IF Erklärungen der Abkürzungen ansehen.
Mouse IgG1 SR: human
Immunogen: Recombinant protein corresponding to aa94-202 of human TP53.
USBio
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100 µl

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789 €

P1001-28H-HRP.100
ELISA, WB, IHC, IF Erklärungen der Abkürzungen ansehen.
Mouse IgG1 SR: human
Immunogen: Recombinant protein corresponding to aa94-202 of human TP53.
USBio
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100 µl

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789 €

P1001-28H-PE.100
ELISA, WB, IHC, IF Erklärungen der Abkürzungen ansehen.
Mouse IgG1 SR: human
Immunogen: Recombinant protein corresponding to aa94-202 of human TP53.
USBio
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100 µl

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789 €

P1001-28J.500
IP, IHC, ICC, FC, IF Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Mouse IgG2a SR: human, monkey
Immunogen: Recombinant corresponding to wild type p53 protein. Cellular Localization: Nuclear.
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500 µl

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676 €

P1001-28K.250
IHC Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Recombinant corresponding to human full-length wild type p53 protein. Cellular Localization: Nuclear.
USBio
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250 µl

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596 €

P1001-28N.100
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Mouse IgG2a SR: human
Immunogen: Recombinant protein, corresponding to amino acids 10-16 of Human p53.
USBio
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100 µg

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596 €

P1001-28S.50
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WB Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to human p53 around the phosphorylation site of serine 46 (M-L-SP-P-D).
USBio
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50 µg

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560 €

P1001-28W.50
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WB, IHC Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to human p53 around the phosphorylation site of serine 315 (S-S-SP-P-Q).
USBio
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50 µg

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560 €

P1001-28Y.100
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WB, IP Erklärungen der Abkürzungen ansehen.
Rabbit SR: human
Immunogen: The epitope recognized maps to a region between residues 50-100 of human tumor protein p53 using the SwissProt entry P04637 (GeneID 7157).
USBio
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100 µl

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726 €

P1001-28Z.100
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WB, IP Erklärungen der Abkürzungen ansehen.
Rabbit SR: human
Immunogen: The epitope recognized maps to a region between residues 325-375 of human tumor protein p53 using the SwissProt entry P04637 (GeneID 7157).
USBio
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100 µl

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726 €

P1001-28Z1.100
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WB Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic non-phosphopeptide corresponding to human p53 around the phosphorylation site of serine 46 (M-L-SP-P-D).
USBio
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100 µg

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625 €

P1001-28Z2.100
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WB Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic non-phosphopeptide corresponding to human p53 around the phosphorylation site of serine 315 (S-S-SP-P-Q).
USBio
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100 µg

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625 €

P1001-29C.100
ELISA, WB, IP, IHC Erklärungen der Abkürzungen ansehen.
Mouse IgG1 SR: bovine, chicken, hamster, human, monkey, mouse, rat
USBio
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100 µg

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496 €

P1001-29D2.500
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Rabbit IgG SR: human
Immunogen: recombinant human full-length wild type p53 protein.
USBio
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500 µl

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442 €

P1001-29F1.50
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WB, IHC Erklärungen der Abkürzungen ansehen.
Mouse IgG1 SR: human
Immunogen: Modified synthetic peptide (RHKKLMFKTEGPDS*D) corresponding to amino acids 378-393 of human p53.
USBio
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50 µg

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703 €

P1001-29G.100
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WB, IP Erklärungen der Abkürzungen ansehen.
Rabbit SR: human
Immunogen: The epitope recognized maps to a region between residues 375-393 (C-terminus)of human tumor protein p53 using the SwissProt entry P04637 (GeneID 7157).
USBio
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100 µl

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726 €

P1001-29P.500
IHC Erklärungen der Abkürzungen ansehen.
Porcine IgG SR: human, mouse, rat
Immunogen: Recombinant full length wild type p53 protein.
USBio
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500 µl

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596 €

P1001-30.200
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WB, IP Erklärungen der Abkürzungen ansehen.
Mouse IgG2a SR: human
USBio
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200 µl

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549 €

P1001-30A1.100
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WB, IHC, ICC, FC Erklärungen der Abkürzungen ansehen.
Mouse SR: human
Immunogen: Synthetic peptide corresponding to aa 16-25 of wild-type and mutant p53.
USBio
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100 µg

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405 €

P1001-30C.200
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WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
USBio
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200 µl

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549 €

P1001-30C1.100
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WB, ICC Erklärungen der Abkürzungen ansehen.
Purity: Supernatant
Rabbit IgG SR: human
Immunogen: A synthetic acetylated peptide corresponding to residues surrounding K382 of human p53.
USBio
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100 µl

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586 €

P1001-30C2.100
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WB, IHC, ICC Erklärungen der Abkürzungen ansehen.
Purity: Supernatant
Rabbit IgG SR: human
Immunogen: A synthetic acetylated peptide corresponding to residues surrounding Ly373 of human p53.
USBio
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100 µl

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537 €

P1001-30D.200
ELISA Erklärungen der Abkürzungen ansehen.
Mouse IgG1 kappa SR: human, mouse
Immunogen: Beta galactosidase-human p53 fusion protein.
USBio
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200 µg

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397 €

P1001-30E.200
ELISA Erklärungen der Abkürzungen ansehen.
Mouse IgG1 kappa SR: human
Immunogen: p53 beta galactosidase fusion protein.
USBio
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200 µg

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408 €

P1001-30F.50
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WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to aa361-382 of human p53 conjugated to human thyroglobulin.
USBio
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50 µl

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566 €

P1001-30F1.100
WB Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic non-phosphopeptide corresponding to human p53 around the phosphorylation site of serine 9 (D-P-SP-V-E).
USBio
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100 µg

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431 €

P1001-30F1.50
WB Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic non-phosphopeptide corresponding to human p53 around the phosphorylation site of serine 9 (D-P-SP-V-E).
USBio
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50 µg

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333 €

P1001-30F2.100
WB, IHC, IF Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic non-phosphopeptide corresponding to human p53 around the phosphorylation site of serine15 (P-L-SP-Q-E).
USBio
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100 µg

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431 €

P1001-30F2.50
WB, IHC, IF Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic non-phosphopeptide corresponding to human p53 around the phosphorylation site of serine15 (P-L-SP-Q-E).
USBio
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50 µg

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333 €

P1001-30F3.100
WB Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic non-phosphopeptide corresponding to human p53 around the phosphorylation site of threonine 18 (Q-E-TP-F-S).
USBio
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100 µg

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431 €

P1001-30F3.50
WB Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic non-phosphopeptide corresponding to human p53 around the phosphorylation site of threonine 18 (Q-E-TP-F-S).
USBio
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50 µg

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333 €

P1001-30F4.100
WB Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human, mouse
Immunogen: Synthetic non-phosphopeptide corresponding to human p53 around the phosphorylation site of serine 6 (P-Q-SP-D-P).
USBio
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100 µg

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431 €

P1001-30F4.50
WB Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human, mouse
Immunogen: Synthetic non-phosphopeptide corresponding to human p53 around the phosphorylation site of serine 6 (P-Q-SP-D-P).
USBio
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50 µg

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333 €

P1001-30F5.100
WB Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic non-phosphopeptide corresponding to human p53 around the phosphorylation site of serine 33 (V-L-SP-P-L).
USBio
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100 µg

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431 €

P1001-30F5.50
WB Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic non-phosphopeptide corresponding to human p53 around the phosphorylation site of serine 33 (V-L-SP-P-L).
USBio
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50 µg

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333 €

P1001-30F6.100
WB Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic non-phosphopeptide corresponding to human p53 around the phosphorylation site of serine 37 (L-P-SP-Q-A).
USBio
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100 µg

Buy Bulk

431 €

P1001-30F6.50
WB Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic non-phosphopeptide corresponding to human p53 around the phosphorylation site of serine 37 (L-P-SP-Q-A).
USBio
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50 µg

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333 €

P1001-30F7.100
WB Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic non-phosphopeptide corresponding to human p53 around the phosphorylation site of serine 46 (M-L-SP-P-D).
USBio
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100 µg

Buy Bulk

431 €

P1001-30F7.50
WB Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic non-phosphopeptide corresponding to human p53 around the phosphorylation site of serine 46 (M-L-SP-P-D).
USBio
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50 µg

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333 €

P1001-30G.100
related products

WB, IHC Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Mouse IgG SR: human
Immunogen: Recombinant human wild-type p53 protein.
USBio
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100 µg

Buy Bulk

578 €

P1001-30Q.100
related products

WB, IP, IHC, ICC, IF Erklärungen der Abkürzungen ansehen.
Mouse IgG2a SR: human
Immunogen: Recombinant human wild-type p53 protein.
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100 µg

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445 €

P1001-30R.100
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Rabbit IgG SR: human
Immunogen: Phosphorylated p53 peptide (ser-37) (KLH).
USBio
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100 µg

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542 €

P1001-30S.100
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Rabbit IgG SR: human
Immunogen: Human p53 peptide (15-40aa) (KLH).
USBio
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100 µg

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542 €

P1001-30T.100
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Rabbit IgG SR: human
Immunogen: Human p53 peptide (15-40aa) (KLH).
USBio
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100 µg

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607 €

P1001-30V.100
WB, IP, IHC, ICC Erklärungen der Abkürzungen ansehen.
Protein function: Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis, the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA- Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Mouse IgG1 SR: human, mouse, rat
Immunogen: Synthetic peptide corresponding to aa surrounding Ser20 of human p53.
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100 µg

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537 €

P1001-30W.100
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Mouse SR: human, mouse
Immunogen: Synthetic peptide corresponding to a portion of p53 phosphorylated at Ser392.
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100 µg

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841 €

P1001-30W.50
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Mouse SR: human, mouse
Immunogen: Synthetic peptide corresponding to a portion of p53 phosphorylated at Ser392.
USBio
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50 µg

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479 €

P1001-30X.100
WB Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis. the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: dog, human, mouse, rabbit, rat
Immunogen: Synthetic peptide surrounding aa375 from human p53.
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100 µg

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456 €

P1001-30Y.100
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Purity: Supernatant
Rabbit IgG SR: human
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Serine 392 of human p53.
USBio
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100 µl

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537 €

P1001-30Z.100
WB, IP, IHC Erklärungen der Abkürzungen ansehen.
Protein function: Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis, the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA- Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human, mouse, rat
Immunogen: Synthetic phosphopeptide surrounding Ser15 of human p53.
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100 µg

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572 €

P1001-32B.500
IHC Erklärungen der Abkürzungen ansehen.
Mouse kappa kappa SR: bovine, human, monkey
USBio
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500 µl

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507 €

P1001-32C.500
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Mouse IgG2a SR: bovine, human, monkey, mouse, rat
USBio
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500 µl

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525 €

P1001-32D.150
ELISA Erklärungen der Abkürzungen ansehen.
Mouse IgG2b SR: human
Immunogen: KLH-conjugated synthetic peptide SHLKSKKGQST corresponding to aa367-377 of human tumor suppressor p53
USBio
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150 µg

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536 €

P1001-32E.150
ELISA Erklärungen der Abkürzungen ansehen.
Mouse IgG1
Immunogen: KLH-conjugated synthetic peptide SHLKS [dimethyl-K]KGQST corresponding to aa367-377 of human tumor suppressor p53
USBio
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150 µg

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536 €

P1001-32G2.100
ELISA, WB Erklärungen der Abkürzungen ansehen.
Purity: Purified by immunoaffinit
Rabbit IgG SR: human
Immunogen: Synthesized non-phosphopeptide derived from human p53 around the phosphorylation site of serine 315 (S-S-SP-P-Q)
USBio
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100 µg

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372 €

P1001-32G3.100
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Purity: Purified by immunoaffinit
Rabbit IgG SR: human
Immunogen: Synthesized phosphopeptide derived from human p53 around the phosphorylation site of serine 315 (S-S-SP-P-Q)
USBio
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100 µg

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447 €

P1001-32G5.100
ELISA, WB Erklärungen der Abkürzungen ansehen.
Purity: Purified by immunoaffinit
Rabbit IgG SR: human
Immunogen: Synthesized phosphopeptide derived from human p53 around the phosphorylation site of serine 46 (M-L-SP-P-D)
USBio
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100 µg

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447 €

P1001-32G6.100
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WB, IP, ICC, FC Erklärungen der Abkürzungen ansehen.
Acts as a tumor suppressor in many tumor types. induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Linear peptide corresponding to p53 (KLH). Epitope: C-Terminus.
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100 µl

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641 €

P1001-32L2.100
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Mouse IgG1 SR: bovine, chicken, hamster, monkey, mouse, rat
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100 µg

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556 €

P1001-32M.100
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Mouse IgG2a SR: human
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100 µg

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568 €

P1001-32N.100
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Mouse IgG2a SR: bovine, human, monkey, mouse, rat
USBio
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100 µg

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588 €

P1001-32S.100
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WB, IP, IHC Erklärungen der Abkürzungen ansehen.
Mouse IgG1 SR: bovine, chicken, hamster, human, monkey, mouse, swine, rat
USBio
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100 µg

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588 €

P1001-32U1.1
IHC Erklärungen der Abkürzungen ansehen.
Mouse kappa kappa SR: human
USBio
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1 ml

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491 €

P9198-08C.100
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Rabbit SR: human
Immunogen: synthetic peptide
USBio
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100 µl

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586 €

P9198-08D.100
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WB Erklärungen der Abkürzungen ansehen.
Rabbit SR: human
Immunogen: synthetic peptide
USBio
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100 µl

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586 €

030929.100
ELISA, WB Erklärungen der Abkürzungen ansehen.
Purity: Ascites
Mouse IgG1 SR: human
Immunogen: EGFR antibody is generated from mouses immunized with a KLH conjugated synthetic peptide between 1163-1191 amino acids from the C-terminal region of human EGFR.
USBio
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100 µl

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482 €

030930-APC.100
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Mouse IgG1 SR: human
Immunogen: EGFR Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from human EGFR.
USBio
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100 µl

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637 €

030930-Biotin.100
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Mouse IgG1 SR: human
Immunogen: EGFR Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from human EGFR.
USBio
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100 µl

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637 €

030930-FITC.100
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Mouse IgG1 SR: human
Immunogen: EGFR Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from human EGFR.
USBio
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100 µl

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637 €

030930-HRP.100
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Mouse IgG1 SR: human
Immunogen: EGFR Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from human EGFR.
USBio
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100 µl

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637 €

030930.100
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Purity: Purified by Protein G aff
Mouse IgG1 SR: human
Immunogen: EGFR Mab is generated from mouses immunized with a KLH conjugated synthetic peptide selected from human EGFR.
USBio
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100 µg

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464 €

034960.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: EGFR antibody is generated from rabbits immunized with EGFR his fusion protein.
USBio
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200 µl

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520 €

034961-APC.200
ELISA, WB, IHC, FC Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: EGFR-S1026 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1010-1029 amino acids from the C-terminal region of human IPO8.
USBio
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200 µl

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637 €

034961-Biotin.200
ELISA, WB, IHC, FC Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: EGFR-S1026 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1010-1029 amino acids from the C-terminal region of human IPO8.
USBio
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200 µl

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637 €

034961-FITC.200
ELISA, WB, IHC, FC Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: EGFR-S1026 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1010-1029 amino acids from the C-terminal region of human IPO8.
USBio
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200 µl

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637 €

034961-HRP.200
ELISA, WB, IHC, FC Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: EGFR-S1026 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1010-1029 amino acids from the C-terminal region of human IPO8.
USBio
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200 µl

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637 €

034961.200
ELISA, WB, IHC, FC Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: EGFR-S1026 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1010-1029 amino acids from the C-terminal region of human IPO8.
USBio
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200 µl

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520 €

034967-APC.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: EGFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the N-terminal region of human EGFR.
USBio
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200 µl

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637 €

034967-Biotin.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: EGFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the N-terminal region of human EGFR.
USBio
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200 µl

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637 €

034967-FITC.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: EGFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the N-terminal region of human EGFR.
USBio
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200 µl

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637 €

034967-HRP.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: EGFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the N-terminal region of human EGFR.
USBio
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200 µl

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637 €

034967.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: EGFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the N-terminal region of human EGFR.
USBio
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200 µl

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521 €

034968-APC.200
ELISA, IHC, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Phospho-EGFR-pS768 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S768 of human EGFR.
USBio
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200 µl

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637 €

034968-Biotin.200
ELISA, IHC, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Phospho-EGFR-pS768 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S768 of human EGFR.
USBio
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200 µl

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637 €

034968-FITC.200
ELISA, IHC, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Phospho-EGFR-pS768 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S768 of human EGFR.
USBio
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200 µl

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637 €

034968-HRP.200
ELISA, IHC, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Phospho-EGFR-pS768 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S768 of human EGFR.
USBio
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200 µl

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637 €

034968.200
ELISA, IHC, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Phospho-EGFR-pS768 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S768 of human EGFR.
USBio
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200 µl

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520 €

E3375-01E.50
IHC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit SR: human
Immunogen: Synthetic peptide, KLH-conjugated. Epitope: C-terminal domain of human
USBio
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50 µg

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642 €

E3375-01F.50
IHC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit SR: human
Immunogen: Synthetic peptide, KLH-conjugated. Epitope: C-terminal domain of human
USBio
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50 µg

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642 €

E3375-01G.50
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ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit SR: human
Immunogen: Synthetic peptide, KLH-conjugated. Epitope: Amino acids 1189-1199 of human EGFR protein.
USBio
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50 µg

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642 €

E3375-01H.50
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ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit SR: human
Immunogen: Synthetic peptide, KLH-conjugated. Epitope: Amino acids 1189-1199 of human EGFR protein.
USBio
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50 µg

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642 €

E3375-04A.100
related products

WB, IP, IHC, ICC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Purity: Supernatant
Rabbit IgG SR: human, mouse, rat
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr1068 of human EGF receptor.
USBio
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100 µl

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586 €

E3375-04B.100
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WB, ICC, FC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Purity: Supernatant
Rabbit IgG SR: human, mouse
Immunogen: A synthetic peptide corresponding to residues surrounding Tyr1068 of human EGF receptor.
USBio
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100 µl

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537 €

E3375-04C.100
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WB, IP, ICC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Purity: Supernatant
Rabbit IgG SR: human
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Serine 1070 and 1071 of human EGF receptor.
USBio
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100 µl

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537 €

E3375-04D.100
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WB, ICC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Purity: Supernatant
Rabbit IgG SR: human
Immunogen: A phospho specific peptide corresponding to residues surrounding threonine 678 of human EGFR.
USBio
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100 µl

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537 €

E3375-04E.100
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WB, IP, ICC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Purity: Supernatant
Rabbit IgG SR: human
Immunogen: A phospho specific peptide corresponding to residues surrounding threonine 693 of human EGFR.
USBio
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100 µl

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537 €

E3375-04F.100
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WB, IP, ICC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Purity: Supernatant
Rabbit IgG SR: human
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyrosine 1110 of human EGF receptor.
USBio
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100 µl

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537 €

E3375-04G.100
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WB, ICC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Purity: Supernatant
Rabbit IgG SR: human
Immunogen: A phospho specific peptide corresponding to residues surrounding tyrosine 845 of human EGFR.
USBio
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100 µl

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537 €

E3375-04H.100
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WB, ICC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: A synthetic peptide corresponding to residues surrounding Serine 695 in human EGFR.
USBio
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100 µl

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537 €

E3375-11A.100
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ELISA, WB Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Mouse IgG1 kappa SR: human
Immunogen: Purified His-tagged EGFR protein (fragment).
USBio
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100 µl

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482 €

E3375-11A1-AP.100
ELISA, WB, IHC, FC Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Mouse IgG1 kappa SR: human
Immunogen: Purified His-tagged EGFR protein (fragment).
USBio
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100 µl

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637 €

E3375-11A1-APC.100
ELISA, WB, IHC, FC Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Mouse IgG1 kappa SR: human
Immunogen: Purified His-tagged EGFR protein (fragment).
USBio
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100 µl

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637 €

E3375-11A1-FITC.100
ELISA, WB, IHC, FC Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Mouse IgG1 kappa SR: human
Immunogen: Purified His-tagged EGFR protein (fragment).
USBio
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100 µl

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637 €

E3375-11A1-HRP.100
ELISA, WB, IHC, FC Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Mouse IgG1 kappa SR: human
Immunogen: Purified His-tagged EGFR protein (fragment).
USBio
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100 µl

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637 €

E3375-11A1-PE.100
ELISA, WB, IHC, FC Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Mouse IgG1 kappa SR: human
Immunogen: Purified His-tagged EGFR protein (fragment).
USBio
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100 µl

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637 €

E3375-11A1.100
related products

ELISA, WB, IHC, FC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Mouse IgG1 kappa SR: human
Immunogen: Purified His-tagged EGFR protein (fragment).
USBio
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100 µg

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668 €

E3375-11H-AP.200
ELISA, WB, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1125 of human EGFR (KLH).
USBio
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200 µl

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637 €

E3375-11H-APC.200
ELISA, WB, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1125 of human EGFR (KLH).
USBio
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200 µl

Buy Bulk

637 €

E3375-11H-Biotin.200
ELISA, WB, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1125 of human EGFR (KLH).
USBio
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200 µl

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637 €

E3375-11H-FITC.200
ELISA, WB, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1125 of human EGFR (KLH).
USBio
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200 µl

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637 €

E3375-11H-HRP.200
ELISA, WB, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1125 of human EGFR (KLH).
USBio
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200 µl

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637 €

E3375-11H-PE.200
ELISA, WB, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1125 of human EGFR (KLH).
USBio
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200 µl

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637 €

E3375-11H.200
related products

ELISA, WB, Gel Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Y1125 of human EGFR (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

521 €

E3375-11K-AP.200
ELISA, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1172 of human EGFR (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

E3375-11K-APC.200
ELISA, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1172 of human EGFR (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

E3375-11K-Biotin.200
ELISA, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1172 of human EGFR (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

E3375-11K-FITC.200
ELISA, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1172 of human EGFR (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

E3375-11K-HRP.200
ELISA, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1172 of human EGFR (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

E3375-11K-PE.200
ELISA, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1172 of human EGFR (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

E3375-11K.200
ELISA, Gel Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Y1172 of human EGFR (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

520 €

E3375-11P-AP.200
ELISA, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1016 of human EGFR (KLH).
USBio
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200 µl

Buy Bulk

637 €

E3375-11P-APC.200
ELISA, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1016 of human EGFR (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

E3375-11P-Biotin.200
ELISA, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1016 of human EGFR (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

E3375-11P-FITC.200
ELISA, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1016 of human EGFR (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

E3375-11P-HRP.200
ELISA, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1016 of human EGFR (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

E3375-11P-PE.200
ELISA, Gel Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr1016 of human EGFR (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

E3375-11P.200
ELISA, Gel Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Y1016 of human EGFR (KLH).
USBio
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200 µl

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521 €

E3375-11R2-AP.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding Y978 of human EGFR (KLH).
USBio
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200 µl

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637 €

E3375-11R2-APC.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding Y978 of human EGFR (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

E3375-11R2-FITC.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding Y978 of human EGFR (KLH).
USBio
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200 µl

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637 €

E3375-11R2-HRP.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding Y978 of human EGFR (KLH).
USBio
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200 µl

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637 €

E3375-11R2-PE.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding Y978 of human EGFR (KLH).
USBio
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200 µl

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637 €

E3375-11R2.200
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ELISA, WB Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding Y978 of human EGFR (KLH).
USBio
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200 µl

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521 €

E3375-11T1-AP.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding S1070 of human EGFR (KLH).
USBio
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200 µl

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637 €

E3375-11T1-APC.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding S1070 of human EGFR (KLH).
USBio
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200 µl

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637 €

E3375-11T1-FITC.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding S1070 of human EGFR (KLH).
USBio
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200 µl

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637 €

E3375-11T1-HRP.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding S1070 of human EGFR (KLH).
USBio
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200 µl

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637 €

E3375-11T1-PE.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding S1070 of human EGFR (KLH).
USBio
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200 µl

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637 €

E3375-11T1.200
related products

ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human, mouse
Immunogen: Synthetic peptide corresponding to amino acid residues surrounding S1070 of human EGFR (KLH).
USBio
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200 µl

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520 €

E3375-11V.200
related products

ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide selected from the N-terminal region of human ErbB1 (KLH).
USBio
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200 µl

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520 €

E3375-12A.100
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WB, IP, IHC, ICC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Mouse IgG1 kappa SR: human, mouse, rat
Immunogen: Recombinant protein encoding the cytoplasmic domain (C-terminal) of human EGF Receptor. Cellular Localization: Cell membrane, Single-pass type I membrane protein. & Isoform 2: Secreted.
USBio
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100 µg

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535 €

E3375-15.50
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ELISA, WB, IP, ICC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Mouse kappa kappa SR: human, mouse
USBio
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50 µg

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570 €

E3375-17G.5 Epidermal Growth Factor Receptor, aa672-​1210, Recombinant, Human (erbB, EGFR) USBio
Icon Datasheet
5 µg

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434 €

E3375-18A.100
WB Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human, mouse, rat
Immunogen: Synthetic non-phosphopeptide corresponding to human EGFR around the phosphorylation site of tyrosine 1197 (A-E-YP-L-R).
USBio
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100 µg

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625 €

E3375-18B.100
WB, IHC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human, mouse, rat
Immunogen: Synthetic non-phosphopeptide corresponding to human EGFR around the phosphorylation site of tyrosine 869 (K-E-YP-H-A).
USBio
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100 µg

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625 €

E3375-18C.100
WB, IHC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human, mouse, rat
Immunogen: Synthetic non-phosphopeptide corresponding to human EGFR around the phosphorylation site of tyrosine 1110 (P-V-YP-H-N).
USBio
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100 µg

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640 €

E3375-18E.50
IHC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to the C-terminal domain of human EGFR.
USBio
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50 µg

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715 €

E3375-22.50
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ELISA, WB Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Chicken SR: human, mouse, rat
USBio
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50 µg

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547 €

E3375-25T.50
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WB, IHC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human, mouse, rat
Immunogen: Synthetic phosphopeptide corresponding to human EGFR around the phosphorylation site of serine 1070 (R-Y-SP-S-D).
USBio
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50 µg

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560 €

E3375-25U.50
related products

WB, IHC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human, mouse, rat
Immunogen: Synthetic phosphopeptide corresponding to human EGFR around the phosphorylation site of tyrosine1092 (P-E-YP-I-N).
USBio
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50 µg

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560 €

E3375-25V.50
related products

WB Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human, mouse, rat
Immunogen: Synthetic phosphopeptide corresponding to human EGFR around the phosphorylation site of threonine 678 (K-R-TP-L-R).
USBio
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50 µg

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560 €

E3375-25W.50
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WB Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human, mouse, rat
Immunogen: Synthetic phosphopeptide corresponding to human EGFR around the phosphorylation site of threonine 693 (P-L-TP-P-S).
USBio
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50 µg

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560 €

E3375-25X.50
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WB, IHC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human, mouse, rat
Immunogen: Synthetic phosphopeptide corresponding to human EGFR around the phosphorylation site of tyrosine 1172 (P-D-YP-Q-Q).
USBio
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50 µg

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560 €

E3375-25Y.50
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WB, IHC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human, mouse, rat
Immunogen: Synthetic phosphopeptide corresponding to human EGFR around the phosphorylation site of tyrosine 1197 (A-E-YP-L-R).
USBio
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50 µg

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560 €

E3375-25Z.50
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WB Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human, mouse, rat
Immunogen: Synthetic phosphopeptide corresponding to human EGFR around the phosphorylation site of tyrosine 869 (K-E-YP-H-A).
USBio
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50 µg

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560 €

E3375-26R.100
WB, IP Erklärungen der Abkürzungen ansehen.
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS- RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human, mouse
Immunogen: Synthetic peptide corresponding to human EGFR.
USBio
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100 µl

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479 €

E3375-47C.10
Enzyme assays Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]
USBio
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10 µg

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516 €

E3375-47D.10
Enzyme assays Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]
USBio
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10 µg

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516 €

E3375-47E.10
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

MW: 88 kD
Purity: 80%
USBio
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10 µg

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516 €

E3375-48A.10
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

MW: 88 kD
Purity: 70%
USBio
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10 µg

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516 €

E3375-53K.50
related products

WB Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human, mouse, rat
Immunogen: Synthetic phosphopeptide corresponding to human EGFR around the phosphorylation site of tyrosine 1110 (P-V-pY-H-N).
USBio
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50 µg

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560 €

E3375-53L.100
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WB, IHC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human, mouse, rat
Immunogen: Synthetic non-phosphopeptide corresponding to human EGFR around the phosphorylation site of serine1070 (R-Y-SP-S-D).
USBio
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100 µg

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625 €

E3375-53M.100
related products

WB, IHC Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human, mouse, rat
Immunogen: Synthetic non-phosphopeptide corresponding to human EGFR around the phosphorylation site of tyrosine 1092 (P-E-YP-I-N).
USBio
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100 µg

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625 €

E3375-53N.100
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WB Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human, mouse, rat
Immunogen: Synthetic non-phosphopeptide corresponding to human EGFR around the phosphorylation site of threonine 678 (K-R-TP-L-R).
USBio
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100 µg

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625 €

E3375-53P.100
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WB Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human, mouse, rat
Immunogen: Synthetic non-phosphopeptide corresponding to human EGFR around the phosphorylation site of threonine 693 (P-L-TP-P-S).
USBio
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100 µg

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625 €

E3375-53Q.100
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WB Erklärungen der Abkürzungen ansehen.
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [The UniProt Consortium]

Rabbit IgG SR: human, mouse, rat
Immunogen: Synthetic non-phosphopeptide corresponding to human EGFR around the phosphorylation site of tyrosine 1172 (P-D-YP-Q-Q).
USBio
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100 µg

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625 €

029722.100
WB, IHC Erklärungen der Abkürzungen ansehen.
Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity (By similarity). Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER-dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. [The UniProt Consortium]

Rabbit IgG SR: chicken, human, monkey, mouse, rat
Immunogen: Synthetic peptide corresponding to aa737-751 from human amyloid A4 protein precursor (APP) or aa85-99 of the C99 fragment generated by b-secretase cleavage.
USBio
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100 µg

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479 €

031995-APC.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: APP-Y756 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Y756 region of human APP .
USBio
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200 µl

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637 €

031995-Biotin.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: APP-Y756 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Y756 region of human APP .
USBio
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200 µl

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637 €

031995-FITC.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: APP-Y756 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Y756 region of human APP .
USBio
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200 µl

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637 €

031995-HRP.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: APP-Y756 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Y756 region of human APP .
USBio
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200 µl

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637 €

031995.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity (By similarity). Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER-dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: APP-Y756 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Y756 region of human APP .
USBio
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200 µl

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521 €

031996-APC.200
ELISA, WB, IHC, IF Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: APP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-362 amino acids from the Central region of human APP.
USBio
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200 µl

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637 €

031996-Biotin.200
ELISA, WB, IHC, IF Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: APP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-362 amino acids from the Central region of human APP.
USBio
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200 µl

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637 €

031996-FITC.200
ELISA, WB, IHC, IF Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: APP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-362 amino acids from the Central region of human APP.
USBio
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200 µl

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637 €

031996-HRP.200
ELISA, WB, IHC, IF Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: APP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-362 amino acids from the Central region of human APP.
USBio
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200 µl

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637 €

031996.200
ELISA, WB, IHC, IF Erklärungen der Abkürzungen ansehen.
Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity (By similarity). Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER-dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: APP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-362 amino acids from the Central region of human APP.
USBio
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200 µl

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521 €

136753.100
ELISA, WB, IP, IHC, ICC, IF Erklärungen der Abkürzungen ansehen.
Rabbit SR: human, mouse, rat
Immunogen: Synthetic molecular mimic of soluble oligomers.
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100 µl

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540 €

137408.100
ELISA Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide corresponding to aa1-37 from human beta-amyloid at C-terminal. Species Sequence Homology: mouse, rat, monkey, bovine.
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100 µl

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555 €

A1372-19A.100
FC Erklärungen der Abkürzungen ansehen.
Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity (By similarity). Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER-dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. [The UniProt Consortium]

Mouse IgG1 SR: dog
Immunogen: Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein
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100 tests

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491 €

A2275-58X.100
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Recognizes human Amyloid Beta A4 precusor (APP).

Rabbit SR: human, mouse, rat
Immunogen: synthetic peptide
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100 µl

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586 €

A2275-59D2.50
WB, IHC Erklärungen der Abkürzungen ansehen.
Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER- dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. [The UniProt Consortium]

Mouse IgG1 SR: human, mouse, rat
Immunogen: Synthetic peptide corresponding to aa35-42 (MVGGVVIA) of beta-amyloid (1-42).
USBio
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50 µg

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488 €

A2275-59F.100
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WB Erklärungen der Abkürzungen ansehen.
Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity (By similarity). Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER-dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. [The UniProt Consortium]

Purity: Supernatant
Rabbit IgG SR: human
Immunogen: A synthetic peptide corresponding to residues in human Beta-amyloid protein 40.
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100 µl

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537 €

A2275-69D4.100
ELISA Erklärungen der Abkürzungen ansehen.
Purity: Purified by Protein G aff
Mouse IgG1 kappa SR: human
Immunogen: Synthetic peptide corresponding to the C-terminal sequence (MVGGVVIA) of human beta amyloid peptide 42.
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100 µl

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667 €

A2275-69S.100
WB, IP Erklärungen der Abkürzungen ansehen.
Purity: Supernatant
Rabbit SR: human
Immunogen: Synthetic peptide corresponding to residues in human Soluble APP.
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100 µl

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613 €

A2275-69V.100
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ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Goat IgG SR: human
Immunogen: Synthetic peptide corresponding to the aa sequence 44-63 of human amyloid precursor protein.
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100 µl

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566 €

A2275-85H.100
ELISA Erklärungen der Abkürzungen ansehen.
Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity (By similarity). Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER-dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. [The UniProt Consortium]

Rabbit IgG SR: human, rabbit
Immunogen: A synthetic peptide (DAEFRHDSGYEVHH) conjugated to BSA corresponding to aa1-14 of mature human beta amyloid.
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100 µl

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578 €

A2275-85L-AP.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER- dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser730 of human APP (KLH).
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200 µl

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637 €

A2275-85L-APC.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER- dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser730 of human APP (KLH).
USBio
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200 µl

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637 €

A2275-85L-Biotin.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER- dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser730 of human APP (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

A2275-85L-FITC.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER- dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser730 of human APP (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

A2275-85L-HRP.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER- dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser730 of human APP (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

A2275-85L-PE.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER- dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser730 of human APP (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

A2275-85L.200
related products

ELISA, WB Erklärungen der Abkürzungen ansehen.
Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity (By similarity). Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER-dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding S730 of human APP (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

521 €

A2275-85P-AP.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER- dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide selected from the N-terminal region of human APP (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

A2275-85P-APC.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER- dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide selected from the N-terminal region of human APP (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

A2275-85P-Biotin.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER- dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide selected from the N-terminal region of human APP (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

A2275-85P-FITC.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER- dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide selected from the N-terminal region of human APP (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

A2275-85P-HRP.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER- dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide selected from the N-terminal region of human APP (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

A2275-85P-PE.200
ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER- dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide selected from the N-terminal region of human APP (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

A2275-85P.200
related products

ELISA, WB, IHC Erklärungen der Abkürzungen ansehen.
Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity (By similarity). Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER-dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. [The UniProt Consortium]

Rabbit IgG SR: human, mouse
Immunogen: Synthetic peptide selected from the N-terminal region of human APP (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

521 €

A2275-85Q-AP.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER- dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide selected from the C-terminal region of human APP (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

A2275-85Q-APC.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER- dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: Synthetic peptide selected from the C-terminal region of human APP (KLH).
USBio
Icon Datasheet
200 µl

Buy Bulk

637 €

A2275-85Q-Biotin.200
ELISA, WB Erklärungen der Abkürzungen ansehen.
Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with