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Anti-NF-kappaB (p65) (amino acids 2-17)

ART NR.: Cay13757-1 (1 each)

Hersteller: Cayman

Datenblatt

Anwendungen: WB

Wirt: Rabbit

Isotyp: IgG

Reaktivität: human

Immunogen: Synthetic peptide corresponding to human NF-kappaB (p65) amino acids 2-17

Lagerung: -20°C

Versand: -20°C

Cay13757-1

1 each

280 €

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Bemerkungen: NF-kappaB regulates the expression of a large number of genes that play critical roles in apoptosis, viral replication, tumorigenesis, various autoimmune diseases, and inflammation. The active nuclear form of the NF-kappaB transcription factor complex is composed of two DNA binding subunits, NF-kappaB p65 and p50, both of which share extensive N-terminal sequence homology with the v-rel oncogene product. N-terminal regions of p50 and p65 are critical for DNA binding and help determine the DNA-binding specificities of p50 and p65.

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