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Cay13784-1
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IHC, WB Erklärungen der Abkürzungen ansehen.
Histone H3.3 is a nuclear protein and a replication-​independent member of the histone H3 family that has a role in nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an ... mehr
Rabbit IgG SR: chicken, ovine, drosophila, equine, human, murine, opossum
Immunogen: synthetic peptide from human Histone H3.3 amino acids 100-150
Cayman
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1 each

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313 €

Cay13754-1
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WB Erklärungen der Abkürzungen ansehen.
The active nuclear form of the NF-​kappaB transcription factor complex is composed of two DNA binding subunits, NF-​kappaB p65 and p50, both of which share extensive N-​terminal sequence homology with the v-​rel oncogene product. N-​terminal regions of p50 and ... mehr
Rabbit IgG SR: human, chimpanzee, rhesus monkey
Immunogen: portion of amino acids 1-50 of human NF-kappaB (p50)
Cayman
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1 each

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296 €

Cay13775-1
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WB Erklärungen der Abkürzungen ansehen.
DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. A de ... mehr
Rabbit IgG SR: human
Immunogen: mixture of synthetic peptides corresponding to amino acids 11-25 and 181-195 of human MeCP2
Cayman
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1 each

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280 €

Cay13779-1
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WB Erklärungen der Abkürzungen ansehen.
Human MutL Homologue (hMLH1) is homologous to the bacterial DNA mismatch repair mutL gene. Mutations in the hMLH1 gene are associated with hereditary non-polyposis colon cancer and various other cancers.
Mouse IgG1 kappa SR: human
Immunogen: synthetic peptide from human MLH1 amino acids 387-403
Cayman
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1 each

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307 €

Cay13789-1
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WB, IHC Erklärungen der Abkürzungen ansehen.
100 µg of purified antibody.
Rabbit IgG SR: human*wide
Immunogen: synthetic peptide
Cayman
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1 each

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321 €

Cay13776-1
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WB Erklärungen der Abkürzungen ansehen.
Mammalian STE-​20-​like kinase 1 (MST-​1) is a serine/threonine kinase that, upon cleavage, has been implicated in the promotion of chromatin condensation. The C-​terminus of MST-​1 contains two functional nuclear export signals (NESs), which are released upon ... mehr
Rabbit IgG SR: human
Immunogen: synthetic peptide from human MST-1 amino acids 372-390
Cayman
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1 each

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296 €

Cay700360-96
Demethylation assays, JMJD2A inhibitor screening Erklärungen der Abkürzungen ansehen.
Caymans JMJD2A Inhibitor Screening Assay Kit provides a convenient fluorescence-​based method for screening JMJD2A inhibitors. The assay is based on the multistep reaction in which JMJD2A first produces formaldehyde during the demethylation of the trimethy ... mehr
Cayman
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manual
96 wells

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413 €

Cay13782-1
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WB Erklärungen der Abkürzungen ansehen.
I2PP2A/SET is a multitasking protein, involved in apoptosis, transcription, nucleosome assembly, and histone binding. The SET gene produces two isoforms from transcript variants. Isoform 1 and 2 interact directly with each other and with ANP32A within the ... mehr
Rabbit IgG SR: human
Immunogen: synthetic peptides from human I2PP2A/SET amino acids 79-94 and 148-164
Cayman
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1 each

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307 €

Cay13783-1
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WB Erklärungen der Abkürzungen ansehen.
Acidic leucine-​rich nuclear phosphoprotein 32 family member A (ANP32A) has been implicated in a nuclear of cellular processes. These include proliferation, differentiation, caspase-​dependent, caspase-​independent apoptosis, suppression of transformation (t ... mehr
Rabbit IgG SR: chimpanzee, ovine, human, rhesus monkey
Immunogen: synthetic peptides from human ANP32A amino acids 87-103 and 231-246
Cayman
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1 each

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307 €

Cay13786-1
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WB Erklärungen der Abkürzungen ansehen.
PMS1 protein homologue 2 (PMS2) is a DNA mismatch repair protein. Defects in PMS2 are a cause of hereditary non-polyposis cancer (HNPCC). Human PMS2 is a protein of 862 amino acids.
Mouse IgG1 SR: murine, human
Immunogen: synthetic peptide from human PMS2 amino acids 623-639
Cayman
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1 each

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320 €


 

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