| 2.332 Treffer |
| ART-NR | PRODUKT | HERSTELLER | MENGE | PREIS |
| 50444.10 |
Interleukin-4, human recombinant (rHuIL-4) Cell culture  Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. (www.uniprot.org) Produced in E.coli. MW: 15.000 D |
Biomol GmbH |
10 µg |
170 €
 |
| 50430.2 |
Interleukin-1 alpha, human recombinant (rHuIL-1-alpha) Cell culture Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 159 amino acids. The ED50 as determined by the dose-dependant stimulation of murine D10S cells is < 0.001 ng/ml. MW: 18.022 D |
Biomol GmbH |
2 µg |
66 €
|
| 94992.10 |
Thrombopoietin, human recombinant (rHuTPO-CHO) Cell biology studies Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. (www.uniprot.org) Produced in CHO as a polypeptide chain containing 332 amino acids. As a result of glycosylation, the recombinant protein migrates with an apparent molecular mass of 80±10 kDa in SDS-PAGE. MW: 35.000 D |
Biomol GmbH |
10 µg |
170 €
|
| BM-13002-10000 |
Razor(TM) TEV Protease (10 000 U) Protein cleavage, Tag removal Ready for use. Recombinant TEV protease with an N-terminal His-tag for simple removal from the cleavage reaction by immobilization on metal-affinity resins. TEV protease recognizes a linear epitope of the general form E-Xaa-Xaa-Y-Xaa-Q-(G/S), with cleavage occuring between Q and G or Q and S. The most commonly used sequence is ENLYFQG. This TEV protease contains a S219V mutation against autoproteolysis (self cleavage) and for increased catalytic activity and efficacy compared to the wild type enzyme. It is mainly used for removing affinity tags from peptides. Affinity tags are often applied to facilitate the expression and purification of recombinant proteins. Whereas many tagged proteins retain their structural integrity and biological activity, others clearly do not. Therefore, whenever possible, it is prudent to remove tags from recombinant proteins. The tobacco vein mottling virus (TVMV) protease is a close relative of TEV protease but, with a distinct sequence specificity. MW: 28 kD Purity: >95% |
Biomol GmbH |
10000 U |
793 €
|
| 50433.2 |
Interleukin-3, human recombinant (rHuIL-3) Cell culture Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated polypeptide chain containing 133 amino acids. The ED50 as determined by the dose-dependant stimulation of TF-1 cells is < 0.1 ng/ml. MW: 15.000 D |
Biomol GmbH |
2 µg |
66 €
|
| 52617.2 |
Interleukin-9, human recombinant (rHuIL-9) Cell culture Supports IL-2 independent and IL-4 independent growth of helper T-cells. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated single polypeptide chain containing 127amino acids. The ED50 as determined by the dose-dependant stimulation of human MO7e cells is < 0.2 ng/ml, corr. to a Specific Activity of 5 x 106 IU/mg. MW: 14.000 D |
Biomol GmbH |
2 µg |
66 €
|
| 22166.25 |
3,3',5,5'-Tetramethylbenzidine (TMB) ultra pure CAS: 54827-17-7 Substrate for peroxidase Use as water soluble, non-carcinogenic peroxidase substrate for ELISA application. Further applications: detection of cholesterol in blood serum, and blood in urine. Measure absorbance of the yellow reaction product at 450 nm. MW: 240 Formula: C16H20N2 |
Biomol GmbH |
25 g |
173 €
|
| BM-13001-1000 |
Razor(TM) TVMV Protease (1000 U) Protein cleavage, Tag removal Ready for use. Recombinant TVMV protease with an N-terminal His-tag for simple removal from the cleavage reaction by immobilization on metal-affinity resins. TVMV protease cleaves the sequence ETVRQS, with cleavage occuring between Q and S residues with high specifity. It is mainly used for removing affinity tags from peptides. Affinity tags are often applied to facilitate the expression and purification of recombinant proteins. Whereas many tagged proteins retain their structural integrity and biological activity, others clearly do not. Therefore, whenever possible, it is prudent to remove tags from recombinant proteins. The tobacco vein mottling virus (TVMV) protease is a close relative of TEV protease but, with a distinct sequence specificity. MW: 27 kD Purity: >95% |
Biomol GmbH |
1000 U |
134 €
|
| BM-13001-10000 |
Razor(TM) TVMV Protease (10 000 U) Protein cleavage, Tag removal Ready for use. Recombinant TVMV protease with an N-terminal His-tag for simple removal from the cleavage reaction by immobilization on metal-affinity resins. TVMV protease cleaves the sequence ETVRQS, with cleavage occuring between Q and S residues with high specifity. It is mainly used for removing affinity tags from peptides. Affinity tags are often applied to facilitate the expression and purification of recombinant proteins. Whereas many tagged proteins retain their structural integrity and biological activity, others clearly do not. Therefore, whenever possible, it is prudent to remove tags from recombinant proteins. The tobacco vein mottling virus (TVMV) protease is a close relative of TEV protease but, with a distinct sequence specificity. MW: 27 kD Purity: >95% |
Biomol GmbH |
10000 U |
793 €
|
| 01280.1 |
Agarose, high electroendosmosis CAS: 9012-36-6 Electrophoresis , immunodiffusion Suitable for immunoelectrophoresis, immunodiffusion, immunoelectrophoresis. |
Biomol GmbH |
1 kg |
720 €
|
| 01280.100 |
Agarose, high electroendosmosis CAS: 9012-36-6 Electrophoresis , immunodiffusion Suitable for immunoelectrophoresis, immunodiffusion, immunoelectrophoresis. |
Biomol GmbH |
100 g |
90 €
|
| 01400.1 |
Albumin bovine (BSA) Fraction V CAS: 9048-46-8 Protein stabilization Useful for stabilizing proteins and enzymes against proteolysis and denaturation. Especially useful, if the protein or enzyme of interest is present at low concentration. MW: 67.000 |
Biomol GmbH |
1 kg |
750 €
|
| 01400.100 |
Albumin bovine (BSA) Fraction V CAS: 9048-46-8 Protein stabilization Useful for stabilizing proteins and enzymes against proteolysis and denaturation. Especially useful, if the protein or enzyme of interest is present at low concentration. MW: 67.000 |
Biomol GmbH |
100 g |
98 €
|
| 01503.25 |
Ampicillin Na-salt CAS: 69-52-3 Antibiotic Crystalline, H2O: <2%, It is effective against gram-positive and some gram-negative bacteria, inhibiting cell wall synthesis. MW: 371 Formula: C16H18N3O4SNa |
Biomol GmbH |
25 g |
58 €
|
| 01503.5 |
Ampicillin Na-salt CAS: 69-52-3 Antibiotic Crystalline, H2O: <2%, It is effective against gram-positive and some gram-negative bacteria, inhibiting cell wall synthesis. MW: 371 Formula: C16H18N3O4SNa |
Biomol GmbH |
5 g |
19 €
|
| 02249.1 |
5-Bromo-4-chloro-3-indolyl- beta-D-galactopyranoside (X-Gal) CAS: 7240-90-6 Substrate for beta-galactosidase Purity: 99% (HPLC). Soluble in DMF and methanol. For use in immunocytochemistry and molecular biology. MW: 409 Formula: C14H15BrClNO6 |
Biomol GmbH |
1 g |
71 €
|
| 02249.10 |
5-Bromo-4-chloro-3-indolyl- beta-D-galactopyranoside (X-Gal) CAS: 7240-90-6 Substrate for beta-galactosidase Purity: 99% (HPLC). Soluble in DMF and methanol. For use in immunocytochemistry and molecular biology. MW: 409 Formula: C14H15BrClNO6 |
Biomol GmbH |
10 g |
507 €
|
| 02249.5 |
5-Bromo-4-chloro-3-indolyl- beta-D-galactopyranoside (X-Gal) CAS: 7240-90-6 Substrate for beta-galactosidase Purity: 99% (HPLC). Soluble in DMF and methanol. For use in immunocytochemistry and molecular biology. MW: 409 Formula: C14H15BrClNO6 |
Biomol GmbH |
5 g |
294 €
|
02291.1 |
BCIP 5-Bromo-4-chloro-3-indolyl- phosphate toluidine salt (X-Phosphate) CAS: 6578-06-9 Substrate for alkaline phosphatase Soluble in DMF, hardly soluble in water. Use as alkaline phosphatase substrate forming a water insoluble blue reaction product. Often used together with NBT (Art.-Nr. 06428) for immunocytochemistry. MW: 434 Formula: C15H15BrClN2O4P |
Biomol GmbH |
1 g |
136 €
|
| 02450.1 |
Cesiumchloride 99,999% CAS: 7647-17-8 Density gradient centrifugation Absorbance (1 cm/50% in water/260 nm): max. 0.02. MW: 168 Formula: CsCl |
Biomol GmbH |
1 kg |
385 €
|
|
03282.50 |
Coomassie Brilliant Blue G250 CAS: 6104-58-1 Protein staining dye For post-electrophoresis staining. This product has a similar sensitivity, but lower solubility compared to R250 (03285). Destaining for removing background is faster compared to R250 (03285). MW: 854 |
Biomol GmbH |
50 g |
41 €
|
| 03466.1 |
Cytochrome C CAS: 9007-43-6 Source: horse heart. Purity: >98%. Cytochrome c is a single polypeptide chain with a covalently attached heme group. MW: 12.500 |
Biomol GmbH |
1 g |
236 €
|
| 04010.25 |
1,4 Dithiothreitol (DTT) CAS: 3483-12-3 Reducing agent Cleland's reagent. Protective reagent for sulfhydryl groups of proteins and enzymes. maintains monothiols in the reduced state and reduces disulfides quantitatively. MW: 154 Formula: C4H10O2S2 |
Biomol GmbH |
25 g |
119 €
|
| 04010.5 |
1,4 Dithiothreitol (DTT) CAS: 3483-12-3 Reducing agent Cleland's reagent. Protective reagent for sulfhydryl groups of proteins and enzymes. maintains monothiols in the reduced state and reduces disulfides quantitatively. MW: 154 Formula: C4H10O2S2 |
Biomol GmbH |
5 g |
33 €
|
|
04051.1 |
Sodium dodecyl sulfate (SDS) CAS: 151-21-3 Anionic detergent Technical grade quality MW: 288 |
Biomol GmbH |
1 kg |
30 €
|
| 04943.1 |
Glycine p.A. Aminoacetic acid CAS: 56-40-6 Buffer component, Protein stabilization Purity: >99.0%. Widely used as a buffer component in Laemmli gels and other applications. MW: 75 Formula: C2H5NO2 |
Biomol GmbH |
1 kg |
25 €
|
| 04943.2500 |
Glycine p.A. Aminoacetic acid CAS: 56-40-6 Buffer component, Protein stabilization Purity: >99.0%. Widely used as a buffer component in Laemmli gels and other applications. MW: 75 Formula: C2H5NO2 |
Biomol GmbH |
2500 g |
59 €
|
| 04943.5 |
Glycine p.A. Aminoacetic acid (2 x 2.5 kg) CAS: 56-40-6 Buffer component, Protein stabilization Purity: >99.0%. Widely used as a buffer component in Laemmli gels and other applications. MW: 75 |
Biomol GmbH |
5 kg |
106 €
|
| 05288.1 |
HEPES p.A. N-2-Hydroxyethylpiperazine- N'-2-ethane sulfonic acid CAS: 7365-45-9 Useful pH range 7.0-8.0 MW: 238 Formula: C8H18N2O4S |
Biomol GmbH |
1 kg |
245 €
|
| 05288.100 |
HEPES p.A. N-2-Hydroxyethylpiperazine- N'-2-ethane sulfonic acid CAS: 7365-45-9 Useful pH range 7.0-8.0 MW: 238 Formula: C8H18N2O4S |
Biomol GmbH |
100 g |
31 €
|
| 05288.250 |
HEPES p.A. N-2-Hydroxyethylpiperazine- N'-2-ethane sulfonic acid CAS: 7365-45-9 Useful pH range 7.0-8.0 MW: 238 Formula: C8H18N2O4S |
Biomol GmbH |
250 g |
68 €
|
|
05684.1 |
Isopropyl-beta-D-thiogalacto- pyranoside (IPTG) CAS: 367-93-1 Inducer of beta-galactosidase Purity: >99%. Free of dioxane and other solvents. For use im molecular biology. In combination with X-Gal (cat# 02249) it is used to detect lac+ colonies in cloning experiments. MW: 238 Formula: C9H18O5S |
Biomol GmbH |
1 g |
27 €
|
|
05684.25 |
Isopropyl-beta-D-thiogalacto- pyranoside (IPTG) CAS: 367-93-1 Inducer of beta-galactosidase Purity: >99%. Free of dioxane and other solvents. For use im molecular biology. In combination with X-Gal (cat# 02249) it is used to detect lac+ colonies in cloning experiments. MW: 238 Formula: C9H18O5S |
Biomol GmbH |
25 g |
387 €
|
|
05684.5 |
Isopropyl-beta-D-thiogalacto- pyranoside (IPTG) CAS: 367-93-1 Inducer of beta-galactosidase Purity: >99%. Free of dioxane and other solvents. For use im molecular biology. In combination with X-Gal (cat# 02249) it is used to detect lac+ colonies in cloning experiments. MW: 238 Formula: C9H18O5S |
Biomol GmbH |
5 g |
98 €
|
| 06170.1 |
MOPS p.A. 3-(N-Morpholino) propane- sulfonic acid CAS: 1132-61-2 Useful pH range: 6.5-7.9 MW: 209 Formula: C7H15NO4S |
Biomol GmbH |
1 kg |
226 €
|
|
06428.1 |
Nitroblue Tetrazolium- chloride (NBT) CAS: 298-83-9 Substrate for dehydrogenases and other oxygenases. Often used in conjunction with BCIP (02291) for AP staining. MW: 818 |
Biomol GmbH |
1 g |
45 €
|
| 08003.1 |
TRIS ultra pure p.A. Tris-(hydroxymethyl)- amino methane CAS: 77-86-1 Purity: >99.9%. pKa(20 °C)=8.3. Highest purity for use in molecular biology. MW: 121 Formula: C4H11NO3 |
Biomol GmbH |
1 kg |
81 €
|
| 08003.2500 |
TRIS ultra pure p.A. Tris-(hydroxymethyl)- amino methane CAS: 77-86-1 Purity: >99.9%. pKa(20 °C)=8.3. Highest purity for use in molecular biology. MW: 121 Formula: C4H11NO3 |
Biomol GmbH |
2500 g |
164 €
|
| 08003.500 |
TRIS ultra pure p.A. Tris-(hydroxymethyl)- amino methane CAS: 77-86-1 Purity: >99.9%. pKa(20 °C)=8.3. Highest purity for use in molecular biology. MW: 121 Formula: C4H11NO3 |
Biomol GmbH |
500 g |
50 €
|
| 08390.30 |
Dialysis-Membrane Type 8 cut-off:12-16 kD pore size 25A diameter 6 mm, width 10 mm Extremely low non-specific protein binding: < 1 ng/g |
Biomol GmbH |
30 m |
124 €
|
| 08390.300 |
Dialysis-Membrane Type 8 cut-off:12-16 kD pore size 25A diameter 6 mm, width 10 mm Extremely low non-specific protein binding: < 1 ng/g |
Biomol GmbH |
300 m |
1051 €
|
| 08395.30 |
Dialysis-Membrane Type 20 cut-off:12-16 kD pore size 25A diameter 16 mm, width 25 mm Extremely low non-specific protein binding: < 1 ng/g |
Biomol GmbH |
30 m |
44 €
|
| 08395.300 |
Dialysis-Membrane Type 20 cut-off:12-16 kD pore size 25A diameter 16 mm, width 25 mm Extremely low non-specific protein binding: < 1 ng/g |
Biomol GmbH |
300 m |
396 €
|
| 08400.30 |
Dialysis-Membrane Type 27 cut-off:12-16 kD pore size 25A diameter 21 mm, width 33 mm Extremely low non-specific protein binding: < 1 ng/g |
Biomol GmbH |
30 m |
52 €
|
| 08400.300 |
Dialysis-Membrane Type 27 cut-off:12-16 kD pore size 25A diameter 21 mm, width 33 mm Extremely low non-specific protein binding: < 1 ng/g |
Biomol GmbH |
300 m |
441 €
|
|
10001 |
Biomol 50bp DNA Ladder, ready to use DNA size standard For 100 applications. Contains a unique combination of PCR products and a number of proprietary plasmids digested with appropriate restriction enzymes to yield 17 fragments, suitable for use as molecular weight standards for agarose gel electrophoresis. The DNA includes fragments ranging from 50-1,500 base pairs. The 200 and 500 base pair bands have increased intensity to serve as reference points. The approximate mass of DNA in each band is provided (0.5 µg a load) for approximating the mass of DNA in comparably intense samples of similar size. |
Biomol GmbH |
500 µl |
66 €
|
|
10002 |
Biomol 100bp DNA Ladder 1, ready-to-use DNA size standard For 100 applications. Contains a unique combination of PCR products and a number of proprietary plasmids digested with appropriate restriction enzymes to yield 11 fragments, suitable for use as molecular weight standards for agarose gel electrophoresis. The DNA includes fragments ranging from 100-1,500 base pairs. The 500 and 1,500 base pair bands have increased intensity to serve as reference points. The approximate mass of DNA in each band is provided (0.5 µg a load) for approximating the mass of DNA in comparably intense samples of similar size. |
Biomol GmbH |
500 µl |
36 €
|
|
10003 |
Biomol 100bp DNA Ladder 2, ready-to-use DNA size standard For 100 applications. Contains a unique combination of PCR products and a number of proprietary plasmids digested with appropriate restriction enzymes to yield 12 fragments, suitable for use as molecular weight standards for agarose gel electrophoresis. The DNA includes fragments ranging from 100-3,000 base pairs. The 500 and 1,500 base pair bands have increased intensity to serve as reference points. The approximate mass of DNA in each band is provided (0.5 µg a load) for approximating the mass of DNA in comparably intense samples of similar size. |
Biomol GmbH |
500 µl |
36 €
|
|
10005 |
Biomol 1kb/100bp combined DNA Ladder, ready-to-use DNA size standard For 100 applications. Contains a unique combination of a number of proprietary plasmids digested with appropriate restriction enzymes and PCR products to yield 19 fragments, suitable for use as molecular weight standards for agarose gel electrophoresis. The DNA includes fragments ranging from 100-10,000 base pairs. The 500, 1.5K and 3K bands have increased intensity to serve as reference points. The approximate mass of DNA in each band is provided (0.5 µg a load) for approximating the mass of DNA in comparably intense samples of similar size. |
Biomol GmbH |
500 µl |
66 €
|
|
10006 |
Biomol DNA Ladder extended Range, ready-to-use DNA size standard For 100 applications. The DNA Ladder extended Range is composed of 14 individual DNA fragments: 25K, 10K, 8K, 6K, 5K, 4K, 3K, 2.5K, 2K, 1500, 1000, 750, 500, 250 base pairs. This product contains two enhanced bands (3K and 1K bp) for easy reference. The ladder is ready-to-use, which is premixed with loading buffer dye for direct loading on gel. |
Biomol GmbH |
500 µl |
66 €
|
|
10007 |
Biomol PINK prestained Protein Ladder (10-175 kDa) Protein standard For up to 200 mini gels. Ready to use. The PINKplus Prestained Protein Ladder contains 11 proteins that resolve into sharp, tight bands in the range of 10-175 kDa. The PINKplus Prestained Protein Ladder allows you to monitor molecular weight separation during electrophoresis, estimate molecular weights of proteins of interest, and evaluate western transfer efficiency |
Biomol GmbH |
500 µl |
113 €
|
|
10008 |
Biomol BLUEplus prestained Protein Ladder (10-180 kDa) Protein standard For up to 333 mini gels. The BLUEplus Prestained Protein Ladder is a three-color protein standard with 10 pre-stained proteins covering a wide range molecular weights for 10 to 180 kDa. Proteins are covalently coupled with a blue chromophore except for two reference bands (one green and one red band at 25 kDa and 75 kDa respectively) when separated on SDS-PAGE (Tris-glycine buffer). The BLUEplus Prestained Protein Ladder is designed for monitoring protein separated during SDS-polyacrylamide gel electrophoresis, verification of Western transfer efficiency on membranes (PVDF, nylon, or nitrocellulose) and for approximate sizing of proteins. The ladder is supplied in gel loading buffer and is ready to use. Do not heat, dilute, add reducing agent before loading. |
Biomol GmbH |
500 µl |
113 €
|
|
10009 |
Biomol BLUEplus-wide prestained Protein Ladder (3.5-245 kDa) Protein standard For up to 333 mini gels. The BLUEplus (wide) Prestained Protein Ladder is a three-color protein standard with 13 pre-stained proteins covering a wide range molecular weights from 3.5 to 245 kDa. Proteins are covalently coupled with a blue chromophore except for two reference bands (one green and one red band at 25 kDa and 75 kDa respectively) when separated on SDS-PAGE (Tris-glycine buffer). The BLUEplus (wide) Prestained Protein Ladder is designed for monitoring protein separation during SDS-polyacrylamide gel electrophoresis, verification of Western transfer efficiency on membranes (PVDF, nylon, or nitrocellulose) and for approximating the size of proteins. The ladder is supplied in gel loading buffer and is ready to use. Do not heat, dilute, add reducing agent before loading. |
Biomol GmbH |
500 µl |
132 €
|
|
10010 |
Biomol F-BLUE for DNA Staining DNA staining Ready to use. Biomol F-BLUE is a non-mutagenic fluorescent reagent that produces instant visualization of DNA bands upon Blue Light (LEDs producing a narrow emission peak centered at about 470 nm) or UV illumination of agarose gels. Supplied in Biomol's 6X DNA Loading Buffer, Biomol F-BLUE is used to prepare DNA markers and samples for loading on agarose or polyacrylamide gels. Biomol F-BLUE is the most sensitive stain available for detecting double-stranded DNA (dsDNA). It contains three tracking dyes (Bromophenol Blue, Xylene Cyanol FF, and Orange G) for visually tracking the DNA migration during the electrophoresis process. It is ideal for the environment requiring a safe , non-hazardous alternative to Ethidum Bromide. |
Biomol GmbH |
1 ml |
34 €
|
| 12136.100 |
Leupeptin (Ac-Leu-Leu-Arginal- hemisulfate) CAS: 103476-89-7 Inhibitor Purity: >96.5%, A reversible inhibitor of trypsin-like proteases and cysteine proteases. Soluble in water, ethanol, acetic acid and DMF. Stock solution: 10 mM in water, stable for 1 month at -20 °C. Effective conc.: 1-10 µM. MW: 493 Formula: C20H38N6O4 . 12H2SO4 |
Biomol GmbH |
100 mg |
253 €
|
| 12136.25 |
Leupeptin (Ac-Leu-Leu-Arginal- hemisulfate) CAS: 103476-89-7 Inhibitor Purity: >96.5%, A reversible inhibitor of trypsin-like proteases and cysteine proteases. Soluble in water, ethanol, acetic acid and DMF. Stock solution: 10 mM in water, stable for 1 month at -20 °C. Effective conc.: 1-10 µM. MW: 493 Formula: C20H38N6O4 . 12H2SO4 |
Biomol GmbH |
25 mg |
69 €
|
| 15655.1 |
Thiazolyl blue (MTT) 3-(4,5-Dimethyl-2-thiazolyl)-2 ,5-diphenyl-2H-tetrazolium bromide CAS: 298-93-1 Cell viability assay The water soluble MTT yields a yellowish solution. It is converted by mitochondrial dehydrogenases of metabolically active cells to an insoluble formazan product, which can be solubilized with DMSO. Read at 510 nm. MW: 414 |
Biomol GmbH |
1 g |
23 €
|
| 15655.10 |
Thiazolyl blue (MTT) 3-(4,5-Dimethyl-2-thiazolyl)-2 ,5-diphenyl-2H-tetrazolium bromide CAS: 298-93-1 Cell viability assay The water soluble MTT yields a yellowish solution. It is converted by mitochondrial dehydrogenases of metabolically active cells to an insoluble formazan product, which can be solubilized with DMSO. Read at 510 nm. MW: 414 |
Biomol GmbH |
10 g |
157 €
|
| 16110.1 |
NAD+ beta-Nicotinamide-adenine- dinucleotide, oxidized form CAS: 53-84-9 Assay anhydrous: >99% enzymatically MW: 663 Formula: C21H27N7O14P2 .3H2O |
Biomol GmbH |
1 g |
20 €
|
| 16132.1 |
NADH beta-Nicotinamide-adenine- dinucleotide, reduced Na2-salt CAS: 606-68-8 Assay anhydrous: 98-99% enzymatically MW: 763 |
Biomol GmbH |
1 g |
60 €
|
| 16132.25 |
NADH beta-Nicotinamide-adenine- dinucleotide, reduced Na2-salt CAS: 606-68-8 Assay anhydrous: 98-99% enzymatically MW: 763 |
Biomol GmbH |
25 g |
814 €
|
| 16132.5 |
NADH beta-Nicotinamide-adenine- dinucleotide, reduced Na2-salt CAS: 606-68-8 Assay anhydrous: 98-99% enzymatically MW: 763 |
Biomol GmbH |
5 g |
204 €
|
| 16156.1 |
NADPH beta-Nicotinamide-adenine- dinucleotide phosphate, reduced Na4-salt CAS: 53-57-6 Assay anhydrous: 98-99% enzymatically MW: 833 |
Biomol GmbH |
1 g |
497 €
|
| 16156.100 |
NADPH beta-Nicotinamide-adenine- dinucleotide phosphate, reduced Na4-salt CAS: 53-57-6 Assay anhydrous: 98-99% enzymatically MW: 833 |
Biomol GmbH |
100 mg |
70 €
|
| 16156.500 |
NADPH beta-Nicotinamide-adenine- dinucleotide phosphate, reduced Na4-salt CAS: 53-57-6 Assay anhydrous: 98-99% enzymatically MW: 833 |
Biomol GmbH |
500 mg |
264 €
|
| 16278.5 |
2-Nitrophenyl-beta-D- galactopyranoside (ONPG) CAS: 369-07-3 Substrate for beta-galactosidase Used in transfection studies. MW: 301 |
Biomol GmbH |
5 g |
59 €
|
| 17640.25 |
Pepstatin A CAS: 26305-03-3 Inhibitor of aspartic proteinases Purity: >98% (HPLC). Rev. inhibitor of aspartic proteinases, e.g. cathepsin D, renin, pepsin, bacterial aspartic proteinases and HIV protease. Soluble in MeOH or EtOH at 1 mg/ml, stable for 1 week at 4 °C. Eff. conc.: 1-5 µM. MW: 686 |
Biomol GmbH |
25 mg |
72 €
|
| 22870.1 |
TRICINE analytical grade N-Tris-(hydroxymethyl) methyl glycine CAS: 5704-04-1 Useful pH range: 7.4-8.8 MW: 179 Formula: C6H13NO5 |
Biomol GmbH |
1 kg |
278 €
|
| 22870.100 |
TRICINE analytical grade N-Tris-(hydroxymethyl) methyl glycine CAS: 5704-04-1 Useful pH range: 7.4-8.8 MW: 179 Formula: C6H13NO5 |
Biomol GmbH |
100 g |
39 €
|
| 22870.500 |
TRICINE analytical grade N-Tris-(hydroxymethyl) methyl glycine CAS: 1389475 Useful pH range: 7.4-8.8 MW: 179 Formula: C6H13NO5 |
Biomol GmbH |
500 g |
153 €
|
| 50003.100 |
BIS-TRIS Bis-(2-hydroxyethyl)-imino- tris(hydroxymethyl)methane CAS: 6976-37-0 Useful pH range: 5.8-7.2 MW: 209 Formula: C8H19NO5 |
Biomol GmbH |
100 g |
68 €
|
| 50058.5 |
3-((3-Cholamidopropyl)-di- methylammonio)-1-propane- sulfonate (CHAPS) CAS: 75621-03-3 Zwitterionic detergent Purity: > 99% (HPLC). Combines features of bile salts and N-alkyl sulfobetaines. Suitable for membrane receptor solubilization. MW: 615 Formula: C32H58N2O7S |
Biomol GmbH |
5 g |
70 €
|
| 50164.1 |
Octyl-beta-D-glucopyranoside CAS: 29836-26-8 Nonionic detergent Purity: >99% (HPLC). Suitable for isolation of membrane bound proteins in their native state. MW: 292 |
Biomol GmbH |
1 g |
43 €
|
| 50164.25 |
Octyl-beta-D-glucopyranoside CAS: 29836-26-8 Nonionic detergent Purity: >99% (HPLC). Suitable for isolation of membrane bound proteins in their native state. MW: 292 |
Biomol GmbH |
25 g |
480 €
|
| 50164.5 |
Octyl-beta-D-glucopyranoside CAS: 29836-26-8 Nonionic detergent Purity: >99% (HPLC). Suitable for isolation of membrane bound proteins in their native state. MW: 292 |
Biomol GmbH |
5 g |
176 €
|
| 50195.10 |
Carbenicillin Na2-salt CAS: 4800-94-6 Antibiotic Effective against gram-positive and gram-negative bacteria. It can be used in plant transformation for killing of Agrobacterium after co-cultivation with plant tissue. MW: 422 Formula: C17H16N2O6Na2 |
Biomol GmbH |
10 g |
187 €
|
| 50200.25 |
Adenosine-5'-triphosphate Na2-salt (5'-ATP-Na2) CAS: 987-65-5 Purity: >98% by HPLC MW: 605 |
Biomol GmbH |
25 g |
115 €
|
| 50204.500 |
D-Sorbitol CAS: 50-70-4 Protein stabilization Assay (HPLC): min. 99%. D-Glucitol. The stabilizing effect is concentration dependent (10-40% w/v). MW: 182 Formula: C6H14O6 |
Biomol GmbH |
500 g |
23 €
|
| 50311.1 |
Dodecyl-beta-D-maltoside (min. 99 %) CAS: 69227-93-6 Nonionic detergent Purity: >99% (HPLC). Suitable for membrane receptor solubilization. Like octylglucosides, it forms small uniform micelles, however increase in alkyl chain length contributes greater thermal stability in solution. MW: 511 Formula: C24H46O11 |
Biomol GmbH |
1 g |
85 €
|
| 50340.1 |
5-Bromo-4-chloro-3-indolyl- beta-D-glucuronide CHA-salt (X-Gluc) CAS: 114162-64-0 Substrate for beta-glucuronidase Single spot by TLC. MW: 522 Formula: C20H26BrClN2O7 |
Biomol GmbH |
1 g |
597 €
|
| 50340.100 |
5-Bromo-4-chloro-3-indolyl- beta-D-glucuronide CHA-salt (X-Gluc) CAS: 114162-64-0 Substrate for beta-glucuronidase Single spot by TLC. MW: 522 Formula: C20H26BrClN2O7 |
Biomol GmbH |
100 mg |
80 €
|
| 50340.250 |
5-Bromo-4-chloro-3-indolyl- beta-D-glucuronide CHA-salt (X-Gluc) CAS: 114162-64-0 Substrate for beta-glucuronidase Single spot by TLC. MW: 522 Formula: C20H26BrClN2O7 |
Biomol GmbH |
250 mg |
162 €
|
| 50375.1 |
5-Bromo-3-indolyl-beta-D- galactopyranoside (Bluo-Gal) CAS: 97753-82-7 Substrate for beta-galactosidase Purity: >99%. An alternative to X-Gal for detection of galactosidase, producing a darker blue color. MW: 374 |
Biomol GmbH |
1 g |
148 €
|
| 50402.100 |
Agarose (Standard) low electroendosmosis CAS: 9012-36-6 Electrophoresis, Immunodiffusion, Southern, northern Suitable for crossed immunoelectrophoresis, high resolution protein electrophoresis, immunielectrophoresis, immunodiffusion, analytical nucleic acid (> 1kbp) electrophoresis. Useful conc.: 0.8-2%. |
Biomol GmbH |
100 g |
83 €
|
| 50402.25 |
Agarose (Standard) low electroendosmosis CAS: 9012-36-6 Electrophoresis, Immunodiffusion, Southern, northern Suitable for crossed immunoelectrophoresis, high resolution protein electrophoresis, immunielectrophoresis, immunodiffusion, analytical nucleic acid (> 1kbp) electrophoresis. Useful conc.: 0.8-2%. |
Biomol GmbH |
25 g |
30 €
|
| 50429.1 |
MOPS, sodium salt CAS: 71119-22-7 Useful pH range: 6.5-7.9 MW: 231 Formula: C7H14NO4SNa |
Biomol GmbH |
1 kg |
345 €
|
| 50432.1 |
HEPES sodium salt CAS: 75277-39-3 Useful pH range 7.0-8.0 MW: 260 Formula: C8H17N2O4NaS |
Biomol GmbH |
1 kg |
410 €
|
| 50734.100 |
Phenol, Liquified and Tris saturated CAS: 108-95-2 DNA extraction 0.1% (w/v) 8-hydroxy-quinoline added, extracted in 1 M Tris solution and subsequently equilibrated with 0.1 M Tris solution until pH (H2O) >7.6. In convenient plastic bottles for storage at -20 °C, stable more than 1 year. MW: 94 Formula: C6H5OH |
Biomol GmbH |
100 ml |
28 €
|
| 50734.1500 |
Phenol, Liquified and Tris saturated (15x100 ml) CAS: 108-95-2 DNA extraction 0.1% (w/v) 8-hydroxy-quinoline added, extracted in 1 M Tris solution and subsequently equilibrated with 0.1 M Tris solution until pH (H2O) >7.6. In convenient plastic bottles for storage at -20 °C, stable more than 1 year. MW: 94 Formula: C6H5OH Purity: min. 99,0% |
Biomol GmbH |
1500 ml |
199 €
|
| 50734.2000 |
Phenol, Liquified and Tris saturated (20x100 ml) CAS: 108-95-2 DNA extraction 0.1% (w/v) 8-hydroxy-quinoline added, extracted in 1 M Tris solution and subsequently equilibrated with 0.1 M Tris solution until pH (H2O) >7.6. In convenient plastic bottles for storage at -20 °C, stable more than 1 year. MW: 94 Formula: C6H5OH Purity: min. 99,0% |
Biomol GmbH |
2000 ml |
267 €
|
| 50734.500 |
Phenol, Liquified and Tris saturated (5x100 ml) CAS: 108-95-2 DNA extraction 0.1% (w/v) 8-hydroxy-quinoline added, extracted in 1 M Tris solution and subsequently equilibrated with 0.1 M Tris solution until pH (H2O) >7.6. In convenient plastic bottles for storage at -20 °C, stable more than 1 year. MW: 94 Formula: C6H5OH Purity: min. 99,0% |
Biomol GmbH |
500 ml |
102 €
|
| 50985.1 |
Pefabloc SC CAS: 30827-99-7 Inhibitor of serine proteases Purity: >95% (HPLC). It is a safe and irreversible inhibitor of serine proteases. Soluble in water. Stock solution: 20 mg/ml, stable for 2 months at -20 °C and 1 week at °C, Effective concentration: 50-200 µM, rarely higher. MW: 240 Formula: C8H10FNO2-HCI |
Biomol GmbH |
1 g |
217 €
|
| 50985.100 |
Pefabloc SC CAS: 30827-99-7 Inhibitor of serine proteases Purity: >95% (HPLC). It is a safe and irreversible inhibitor of serine proteases. Soluble in water. Stock solution: 20 mg/ml, stable for 2 months at -20 °C and 1 week at °C, Effective concentration: 50-200 µM, rarely higher. MW: 240 Formula: C8H10FNO2-HCI |
Biomol GmbH |
100 mg |
25 €
|
| 50985.500 |
Pefabloc SC CAS: 30827-99-7 Inhibitor of serine proteases Purity: >95% (HPLC). It is a safe and irreversible inhibitor of serine proteases. Soluble in water. Stock solution: 20 mg/ml, stable for 2 months at -20 °C and 1 week at °C, Effective concentration: 50-200 µM, rarely higher. MW: 240 Formula: C8H10FNO2-HCI |
Biomol GmbH |
500 mg |
117 €
|
| 50990.100 |
Prionex (TM) - Protein stabilizer Protein stabilization Prionex(TM) meets all purity requirements for application as a stabilizer of pharmaceutical polypeptide and protein preparations. It is further suitable as an additive for cell culture media. Heat denaturation protection. MW: 20 |
Biomol GmbH |
100 ml |
anfragen
|
| 52587.50 |
Agarose SP-10, for separating DNA fragments <1000 bp CAS: 9012-36-6 Electrophoresis Superior quality for high resolution of PCR products and small DNA fragments. Also suitable for blotting assays with DNA fragments <=600 bp. Gels show excellent mechanical strength. Free of DNase and RNase contaminants. |
Biomol GmbH |
50 g |
269 €
|
| 52755.100 |
PIPES free acid Piperazine-N,N'-bis(2-ethane- sulfonic acid) CAS: 5625-37-6 Useful pH range: 6.1-7.5 MW: 302 |
Biomol GmbH |
100 g |
67 €
|
| 53087.1 |
ExGen 500 in vitro Transfection Reagent in vitro transfection of DNA ExGen 500, polyethylenimine (PEI), provides superior in vitro transfection efficiencies when compared to various cationic lipids and polymers. It has a low toxicity and works efficiently in the presence or absence of serum. (100-200 tfxn) |
Biomol GmbH |
1 ml |
170 €
|
| 53238.1 |
Ectoine, ultrapure CAS: 96702-03-3 Biopolymer stabilization Purity: >99%. Compatible solute isolated from Halomonas elongata. Ectoine is able to protect and stabilize proteins, nucleic acids and membranes. Protein stabization: 0.1-1 mM, DNA protection: 0.1-10 mM. MW: 142 |
Biomol GmbH |
1 g |
93 €
|
| 54650.1000 |
Non-fat skimmed milk powder Blocking Useful for blocking of surfaces, e. g. in the analysis of proteins and nucleic acids transferred to nitrocellulose. |
Biomol GmbH |
1000 g |
40 €
|
| 54650.500 |
Non-fat skimmed milk powder Blocking Useful for blocking of surfaces, e. g. in the analysis of proteins and nucleic acids transferred to nitrocellulose. |
Biomol GmbH |
500 g |
24 €
|
| 54653.1 |
Salmon sperm DNA sodium salt (sonified) CAS: 9007-49-2 Prevents unspecific binding of probes to membranes in hybridization experiments. DNases/RNases: not detectable. Fragment size: 10-330 base pairs. |
Biomol GmbH |
1 g |
45 €
|
| 54653.10 |
Salmon sperm DNA sodium salt (sonified) CAS: 9007-49-2 Prevents unspecific binding of probes to membranes in hybridization experiments. DNases/RNases: not detectable. Fragment size: 10-330 base pairs. |
Biomol GmbH |
10 g |
268 €
|
| 54657.5 |
Denhardt`s solution (50x) Hybridization Non specific hybridization sites on nitrocellulose filters become saturated by components of Denhardt's solution. |
Biomol GmbH |
5 ml |
34 €
|
| 54666.5 |
TBE buffer (10x) Electrophoresis buffer |
Biomol GmbH |
5 l |
85 €
|
| 54686.100 |
Dimethylsulfoxide (DMSO) p.A. CAS: 67-68-5 Protein stabilization Assay (GC): min. 99.5%. Low concentrations of DMSO can stabilze proteins, although at higher conc. denaturation may occur. 10% DMSO is used for freezing of cells. MW: 78 |
Biomol GmbH |
100 ml |
22 €
|
| 54686.500 |
Dimethylsulfoxide (DMSO) p.A. CAS: 67-68-5 Protein stabilization Assay (GC): min. 99.5%. Low concentrations of DMSO can stabilze proteins, although at higher conc. denaturation may occur. 10% DMSO is used for freezing of cells. MW: 78 |
Biomol GmbH |
500 ml |
37 €
|
| 55459.1 |
Ectoine (Technical Grade) Purity > 95% CAS: 96702-03-3 Biopolymer stabilization Purity: 95%. Applications: see 53238. This quality is not recommended for DNA protection. |
Biomol GmbH |
1 g |
31 €
|
| 56366.1 |
Dodecyl-beta-D-maltoside for crystallography CAS: 69227-93-6 Nonionic detergent Purity: >99.5% (HPLC). Both alcohol and alpha isomer are completely removed during the processing. The anomeric purity of this detergent is of great importance especially for crystallization of membrane proteins. MW: 511 |
Biomol GmbH |
1 g |
115 €
|
| 56366.25 |
Dodecyl-beta-D-maltoside for crystallography CAS: 69227-93-6 Nonionic detergent Purity: >99.5% (HPLC). Both alcohol and alpha isomer are completely removed during the processing. The anomeric purity of this detergent is of great importance especially for crystallization of membrane proteins. MW: 511 |
Biomol GmbH |
25 g |
1586 €
|
| 56366.5 |
Dodecyl-beta-D-maltoside for crystallography CAS: 69227-93-6 Nonionic detergent Purity: >99.5% (HPLC). Both alcohol and alpha isomer are completely removed during the processing. The anomeric purity of this detergent is of great importance especially for crystallization of membrane proteins. MW: 511 |
Biomol GmbH |
5 g |
411 €
|
| 56509.1500 |
Biomol-Starch hydrolysed, for electrophoresis CAS: 9005-84-9 Gel electrophoresis A detailed protocol for preparing horizontal or vertical gels is included. Unlike comparable products the resolution properties of this natural material is extensively tested for every lot. |
Biomol GmbH |
1500 g |
299 €
|
| 62263.1 |
NADP beta-Nicotinamide-adenine- dinucleotide phosphate Disodium CAS: 24292-60-2 Assay of NADP Disodium (enzym) >97% MW: 787 D |
Biomol GmbH |
1 g |
124 €
|
| 62263.5 |
NADP beta-Nicotinamide-adenine- dinucleotide phosphate Disodium CAS: 24292-60-2 Assay of NADP Disodium (enzym) >97% MW: 787 D |
Biomol GmbH |
5 g |
494 €
|
| 62513.5 |
BioStab Biomolecule Storage Solution Storage of biomolecules Improves storage capabilities of enzymes, antibodies, nucleic acids, whole cells and membranes significantly. |
Biomol GmbH |
5 ml |
34 €
|
| BM-HL007R010SG |
HOPE® Trial-Kit Tissue fixation, IHC, ISH For easy starting we offer a HOPE® Trail Kit with 100 ml HOPE® I, 1ml HOPE® II and 500 g Low Melting Paraffin sufficient for fixation of 20 tissue samples. HOPE® = Hepes-glutamic acid buffer mediated Organic solvent Protection Effect - is a new formalin-free tissue conservation technique for tissue fixation, including subsequent paraffin-embedding and sectioning that allows the complete analysis of all types of human or animal soft tissues. HOPE is a combination of amino acids and glucose blended together with an organic buffer. For fixing tissue according to the HOPE® standard fixation protocol, HOPE® I and HOPE® II solution (catalog nr. BM-HL002C001), acetone and Low Melting Point Paraffin (52-54°C, catalog nr. BM-PL003S2K ) are required. During HOPE® fixation, tissue samples are incubated in HOPE® I solution, then in HOPE® II solution, followed by a dehydration with acetone and subsequent embedding in low melting paraffin. No alcohols or aldehydes (formalin, glutaraldehyde) are used. This technique avoids cross-linking of macro- molecular structures during the process which opens up new opportunities to characterize tissues out of paraffin blocks. As a result many 'cryo-type' antibodies are working on HOPE® fixed tissue sections and many antibodies are working without any heat pretreatment or proteolytic digestion steps often necessary for formalin fixed tissue sections. There is no 'over-fixation' with HOPE®, as is known with formalin, when keeping the tissue speci |
Biomol GmbH |
1 kit |
93 €
|
| 86400.10 |
Human Serum Albumin (HSA), recombinant Protein stabilization Recombinant Human Serum Albumin produced in yeast is a single, non-glycosylated, polypeptide chain containing 585 amino acids. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in this gene on chromosome 4 result in various anomalous proteins. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. The human albumin gene is 16,961 nucleotides long from the putative 'cap' site to the first poly (A) addition site. It is split into 15 exons which are symmetrically placed within the 3 domains that are thought to have arisen by triplication of a single primordial domain. MW: 67 kD Purity: >99% |
Biomol GmbH |
10 mg |
272 €
|
| 86400.100 |
Human Serum Albumin (HSA), recombinant Protein stabilization Recombinant Human Serum Albumin produced in yeast is a single, non-glycosylated, polypeptide chain containing 585 amino acids. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in this gene on chromosome 4 result in various anomalous proteins. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. The human albumin gene is 16,961 nucleotides long from the putative 'cap' site to the first poly (A) addition site. It is split into 15 exons which are symmetrically placed within the 3 domains that are thought to have arisen by triplication of a single primordial domain. MW: 67 kD Purity: >99% |
Biomol GmbH |
100 mg |
1254 €
|
| 86400.50 |
Human Serum Albumin (HSA), recombinant Protein stabilization Recombinant Human Serum Albumin produced in yeast is a single, non-glycosylated, polypeptide chain containing 585 amino acids. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in this gene on chromosome 4 result in various anomalous proteins. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. The human albumin gene is 16,961 nucleotides long from the putative 'cap' site to the first poly (A) addition site. It is split into 15 exons which are symmetrically placed within the 3 domains that are thought to have arisen by triplication of a single primordial domain. MW: 67 kD Purity: >99% |
Biomol GmbH |
50 mg |
816 €
|
| 97275.1 |
Apolipoprotein A-I, human recombinant, His Tag (rHuAPO-A1) Bioassay Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. (www.uniprot.org) Human recombinant APOA1 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 264 amino acids (fragment 25-267) and having a molecular mass of 30.3kDa. APOA1 is fused to 20 amino acid His-Tag at N-terminus. APOA1 (Apolipoprotein A-1) is a human protein with a specific role in lipid metabolism being the main protein component of HDL in the plasma. APOA1 promotes cholesterol efflux from tissues to the liver for excretion. Furthermore, APOA1 is a cofactor for LCAT, which is responsible for the formation of most plasma cholesteryl esters. In addition, APOA1 activates spermatozoa motility as part of the SPAP complex. The APOA1 gene is strongly linked with two other apolipoprotein genes on chromosome 11. Defects in the APOA1 gene are linked to HDL deficiency including Tangier disease, and with systemic non-neuropathic amyloidosis. High levels of APOA1 are linked to the manifestation of asthma and atopy. MW: 30.300 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 97275.100 |
Apolipoprotein A-I, human recombinant, His Tag (rHuAPO-A1) Bioassay Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. (www.uniprot.org) Human recombinant APOA1 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 264 amino acids (fragment 25-267) and having a molecular mass of 30.3kDa. APOA1 is fused to 20 amino acid His-Tag at N-terminus. APOA1 (Apolipoprotein A-1) is a human protein with a specific role in lipid metabolism being the main protein component of HDL in the plasma. APOA1 promotes cholesterol efflux from tissues to the liver for excretion. Furthermore, APOA1 is a cofactor for LCAT, which is responsible for the formation of most plasma cholesteryl esters. In addition, APOA1 activates spermatozoa motility as part of the SPAP complex. The APOA1 gene is strongly linked with two other apolipoprotein genes on chromosome 11. Defects in the APOA1 gene are linked to HDL deficiency including Tangier disease, and with systemic non-neuropathic amyloidosis. High levels of APOA1 are linked to the manifestation of asthma and atopy. MW: 30.300 D Purity: >95% |
Biomol GmbH |
100 µg |
170 €
|
| 97275.20 |
Apolipoprotein A-I, human recombinant, His Tag (rHuAPO-A1) Bioassay Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. (www.uniprot.org) Human recombinant APOA1 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 264 amino acids (fragment 25-267) and having a molecular mass of 30.3kDa. APOA1 is fused to 20 amino acid His-Tag at N-terminus. APOA1 (Apolipoprotein A-1) is a human protein with a specific role in lipid metabolism being the main protein component of HDL in the plasma. APOA1 promotes cholesterol efflux from tissues to the liver for excretion. Furthermore, APOA1 is a cofactor for LCAT, which is responsible for the formation of most plasma cholesteryl esters. In addition, APOA1 activates spermatozoa motility as part of the SPAP complex. The APOA1 gene is strongly linked with two other apolipoprotein genes on chromosome 11. Defects in the APOA1 gene are linked to HDL deficiency including Tangier disease, and with systemic non-neuropathic amyloidosis. High levels of APOA1 are linked to the manifestation of asthma and atopy. MW: 30.300 D Purity: >95% |
Biomol GmbH |
20 µg |
66 €
|
| 94911.1 |
Apolipoprotein J, His Tag, human recombinant (rHuAPO-J-His) Cell biology studies Not yet clear. It is known to be expressed in a variety of tissues and it seems to be able to bind to cells, membranes and hydrophobic proteins. It has been associated with programmed cell death (apoptosis). (www.uniprot.org) Produced in HEK293cell line (Human embryonic kidney), containing 454 amino acids. The amino acid sequence 1-427 is identical to Swiss-Prot-P10909 (amino acid 23-449, secreted Human Clusterin), C-terminal His tag 27amino acids. MW: 53.058 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 94911.10 |
Apolipoprotein J, His Tag, human recombinant (rHuAPO-J-His) Cell biology studies Not yet clear. It is known to be expressed in a variety of tissues and it seems to be able to bind to cells, membranes and hydrophobic proteins. It has been associated with programmed cell death (apoptosis). (www.uniprot.org) Produced in HEK293cell line (Human embryonic kidney), containing 454 amino acids. The amino acid sequence 1-427 is identical to Swiss-Prot-P10909 (amino acid 23-449, secreted Human Clusterin), C-terminal His tag 27amino acids. MW: 53.058 D |
Biomol GmbH |
10 µg |
170 €
|
| 94911.2 |
Apolipoprotein J, His Tag, human recombinant (rHuAPO-J-His) Cell biology studies Not yet clear. It is known to be expressed in a variety of tissues and it seems to be able to bind to cells, membranes and hydrophobic proteins. It has been associated with programmed cell death (apoptosis). (www.uniprot.org) Produced in HEK293cell line (Human embryonic kidney), containing 454 amino acids. The amino acid sequence 1-427 is identical to Swiss-Prot-P10909 (amino acid 23-449, secreted Human Clusterin), C-terminal His tag 27amino acids. MW: 53.058 D |
Biomol GmbH |
2 µg |
66 €
|
| 96997.1 |
Apolipoprotein J, human (hApo-J) Cell culture Not yet clear. It is known to be expressed in a variety of tissues and it seems to be able to bind to cells, membranes and hydrophobic proteins. It has been associated with programmed cell death (apoptosis). (www.uniprot.org) Clusterin, also named Apoliprotein J (APO-J), is a 75-80 kD disulfide-linked heterodimeric protein containing about 30% of N-linked carbohydrate rich in sialic acid but truncated forms targeted to the nucleus have also been identified. Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 96997.10 |
Apolipoprotein J, human (hApo-J) Cell culture Not yet clear. It is known to be expressed in a variety of tissues and it seems to be able to bind to cells, membranes and hydrophobic proteins. It has been associated with programmed cell death (apoptosis). (www.uniprot.org) Clusterin, also named Apoliprotein J (APO-J), is a 75-80 kD disulfide-linked heterodimeric protein containing about 30% of N-linked carbohydrate rich in sialic acid but truncated forms targeted to the nucleus have also been identified. |
Biomol GmbH |
10 µg |
170 €
|
| 96997.2 |
Apolipoprotein J, human (hApo-J) Cell culture Not yet clear. It is known to be expressed in a variety of tissues and it seems to be able to bind to cells, membranes and hydrophobic proteins. It has been associated with programmed cell death (apoptosis). (www.uniprot.org) Clusterin, also named Apoliprotein J (APO-J), is a 75-80 kD disulfide-linked heterodimeric protein containing about 30% of N-linked carbohydrate rich in sialic acid but truncated forms targeted to the nucleus have also been identified. |
Biomol GmbH |
2 µg |
66 €
|
| 57272.1 |
Growth Hormone, human recombinant (rHuGH) Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 192 amino acids. Fully biologically active when compared to World Health Organization (WHO) reference standard which is 3 units/mg. MW: 22.260 D Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 57272.100 |
Growth Hormone, human recombinant (rHuGH) Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 192 amino acids. Fully biologically active when compared to World Health Organization (WHO) reference standard which is 3 units/mg. MW: 22.260 D |
Biomol GmbH |
100 µg |
66 €
|
| 57272.500 |
Growth Hormone, human recombinant (rHuGH) Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 192 amino acids. Fully biologically active when compared to World Health Organization (WHO) reference standard which is 3 units/mg. MW: 22.260 D |
Biomol GmbH |
500 µg |
170 €
|
| 87382.1 |
Pituitary Growth Hormone-20K, human, recombinant (rHupitGH-20K) Cell Culture Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 177 amino acids. Biomol's rHuGH-20K is fully biologically active when compared to World Health Organization (WHO) reference standard. MW: 20.322 D Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 87382.10 |
Pituitary Growth Hormone-20K, human, recombinant (rHupitGH-20K) Cell Culture Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 177 amino acids. Biomol's rHuGH-20K is fully biologically active when compared to World Health Organization (WHO) reference standard. MW: 20.322 D |
Biomol GmbH |
10 µg |
66 €
|
| 87382.50 |
Pituitary Growth Hormone-20K, human, recombinant (rHupitGH-20K) Cell Culture Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 177 amino acids. Biomol's rHuGH-20K is fully biologically active when compared to World Health Organization (WHO) reference standard. MW: 20.322 D |
Biomol GmbH |
50 µg |
170 €
|
| 99861.50 |
Growth Hormone, active, His Tag, human recombinant (rHuGH-His), plant based, bio-clean Cell culture, WB Recombinant human Growth Hormone contains a 6-His-tag at the N-terminal end, is produced by transient expression in non-transgenic plants and is purified by sequential chromatography (FPLC). This product contains no animal-derived components or impurities. The biological activity of human Growth Hormone is measured by cell proliferation using Nb2-11 cells. GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. MW: 22 kD Purity: >97% |
Biomol GmbH |
50 µg |
260 €
|
| 50440.1 |
Fibroblast Growth Factor acidic, human recombinant (rHuFGF-acidic) Cell culture The heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 155 amino acids. The ED50, calculated by the dose-dependant proliferation of BAF3 cells expressing FGF receptors (measured by 3H-thymidine uptake) is < 10 ng/ml. MW: 15.500 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 50440.10 |
Fibroblast Growth Factor acidic, human recombinant (rHuFGF-acidic) Cell culture The heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 155 amino acids. The ED50, calculated by the dose-dependant proliferation of BAF3 cells expressing FGF receptors (measured by 3H-thymidine uptake) is < 10 ng/ml. MW: 15.500 D |
Biomol GmbH |
10 µg |
66 €
|
| 50440.50 |
Fibroblast Growth Factor acidic, human recombinant (rHuFGF-acidic) Cell culture The heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 155 amino acids. The ED50, calculated by the dose-dependant proliferation of BAF3 cells expressing FGF receptors (measured by 3H-thymidine uptake) is < 10 ng/ml. MW: 15.500 D |
Biomol GmbH |
50 µg |
170 €
|
| 94956.1 |
Fibroblast Growth Factor acidic, human recombinant (rHuFGF-acidic-Sf9) Cell culture The heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro. (www.uniprot.org) Produced in Sf9 insect cells as a single, glycosylated, polypeptide chain containing 140 amino acids. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. MW: 15.803 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 94956.10 |
Fibroblast Growth Factor acidic, human recombinant (rHuFGF-acidic-Sf9) Cell culture The heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro. (www.uniprot.org) Produced in Sf9 insect cells as a single, glycosylated, polypeptide chain containing 140 amino acids. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. MW: 15.803 D |
Biomol GmbH |
10 µg |
170 €
|
| 94956.2 |
Fibroblast Growth Factor acidic, human recombinant (rHuFGF-acidic-Sf9) Cell culture The heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro. (www.uniprot.org) Produced in Sf9 insect cells as a single, glycosylated, polypeptide chain containing 140 amino acids. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. MW: 15.803 D |
Biomol GmbH |
2 µg |
66 €
|
| 50448.1 |
Interleukin-8, human recombinant (rHuIL-8/72 amino acids) Cell culture IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. (www.uniprot.org) Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 50448.2 |
Interleukin-8, human recombinant (rHuIL-8/72 amino acids) Cell culture Purity: >98% |
Biomol GmbH |
2 µg |
eingest.
|
| 50448.25 |
Interleukin-8, human recombinant (rHuIL-8/72 amino acids) Cell culture IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. (www.uniprot.org) Purity: >98% |
Biomol GmbH |
25 µg |
170 €
|
| 50448.5 |
Interleukin-8, human recombinant (rHuIL-8/72 amino acids) Cell culture IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. (www.uniprot.org) Purity: >98% |
Biomol GmbH |
5 µg |
66 €
|
| 94865.1 |
Interleukin-8 (1-77) (CXCL8), human recombinant (rHuIL-8/1-77) Chemoattract. IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. (www.uniprot.org) Produced in E.coli as a non-glycosylated, polypeptide chain containing 77 amino acids. Interleukin-8 (IL-8) serves as a chemical signal that attracts neutrophils at the site of inflammation. MW: 8.904 D Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 94865.25 |
Interleukin-8 (1-77) (CXCL8), human recombinant (rHuIL-8/1-77) Chemoattract. IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. (www.uniprot.org) Produced in E.coli as a non-glycosylated, polypeptide chain containing 77 amino acids. Interleukin-8 (IL-8) serves as a chemical signal that attracts neutrophils at the site of inflammation. MW: 8.904 D |
Biomol GmbH |
25 µg |
170 €
|
| 94865.5 |
Interleukin-8 (1-77) (CXCL8), human recombinant (rHuIL-8/1-77) Chemoattract. IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. (www.uniprot.org) Produced in E.coli as a non-glycosylated, polypeptide chain containing 77 amino acids. Interleukin-8 (IL-8) serves as a chemical signal that attracts neutrophils at the site of inflammation. MW: 8.904 D |
Biomol GmbH |
5 µg |
66 €
|
| 94882.1 |
Interleukin-8 (1-77) (CXCL8) His Tag, human recombinant (rHuIL-8/1-77-His) Chemoattract. IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 77 amino acids (fragment 23-99) with an amino-terminal hexahistidine tag. MW: 15.000 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 94882.10 |
Interleukin-8 (1-77) (CXCL8) His Tag, human recombinant (rHuIL-8/1-77-His) Chemoattract. IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 77 amino acids (fragment 23-99) with an amino-terminal hexahistidine tag. MW: 15.000 D |
Biomol GmbH |
10 µg |
66 €
|
| 94882.50 |
Interleukin-8 (1-77) (CXCL8) His Tag, human recombinant (rHuIL-8/1-77-His) Chemoattract. IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 77 amino acids (fragment 23-99) with an amino-terminal hexahistidine tag. MW: 15.000 D |
Biomol GmbH |
50 µg |
170 €
|
| 97114.1 |
Interleukin-8 (1-77) (CXCL8), human recombinant (rHuIL-8-Pichia) (rHuIL-8-Pichia) Cell culture IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. (www.uniprot.org) Produced in Yeast as a single, glycosylated polypeptide chain containing 79 amino acids Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 97114.25 |
Interleukin-8 (1-77) (CXCL8), human recombinant (rHuIL-8-Pichia) (rHuIL-8-Pichia) Cell culture IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. (www.uniprot.org) Produced in Yeast as a single, glycosylated polypeptide chain containing 79 amino acids |
Biomol GmbH |
25 µg |
170 €
|
| 97114.5 |
Interleukin-8 (1-77) (CXCL8), human recombinant (rHuIL-8-Pichia) (rHuIL-8-Pichia) Cell culture IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. (www.uniprot.org) Produced in Yeast as a single, glycosylated polypeptide chain containing 79 amino acids |
Biomol GmbH |
5 µg |
66 €
|
| 08568.1 |
Vascular Endothelial Growth Factor-121 (VEGF-121), human recombinant, His Tag (rHuVEGF-121) Cell biology studies Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in E.coli as a double, non-glycosylated, polypeptide chain containing a total of 142 amino acids. The VEGF-121 is fused to 20 amino acid His tag at N-terminus. MW: 16.300 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 08568.10 |
Vascular Endothelial Growth Factor-121 (VEGF-121), human recombinant, His Tag (rHuVEGF-121) Cell biology studies Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in E.coli as a double, non-glycosylated, polypeptide chain containing a total of 142 amino acids. The VEGF-121 is fused to 20 amino acid His tag at N-terminus. MW: 16.300 D |
Biomol GmbH |
10 µg |
170 €
|
| 08568.2 |
Vascular Endothelial Growth Factor-121 (VEGF-121), human recombinant, His Tag (rHuVEGF-121) Cell biology studies Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in E.coli as a double, non-glycosylated, polypeptide chain containing a total of 142 amino acids. The VEGF-121 is fused to 20 amino acid His tag at N-terminus. MW: 16.300 D |
Biomol GmbH |
2 µg |
66 €
|
| 52625.1 |
Vascular Endothelial Growth Factor-121, human recombinant (rHuVEGF-121) Cell Culture Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in E.coli. Homodimer, polypeptide chain containing 2 x 121 amino acids. MW: 28.423 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 52625.10 |
Vascular Endothelial Growth Factor-121, human recombinant (rHuVEGF-121) Cell Culture Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in E.coli. Homodimer, polypeptide chain containing 2 x 121 amino acids. MW: 28.423 D |
Biomol GmbH |
10 µg |
170 €
|
| 52625.2 |
Vascular Endothelial Growth Factor-121, human recombinant (rHuVEGF-121) Cell Culture Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in E.coli. Homodimer, polypeptide chain containing 2 x 121 amino acids. MW: 28.423 D |
Biomol GmbH |
2 µg |
66 €
|
| 52626.1 |
Vascular Endothelial Growth Factor-165, human recombinant (rHuVEGF-165-Sf9) Cell Culture Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in Sf9 insect cells. Double, glycosylated polypeptide chain containing 165 amino acids. MW: 38.231 D Purity: >90% |
Biomol GmbH |
1 mg |
eingest.
|
| 87399.1 |
Vascular Endothelial Growth Factor-165, human recombinant (rHuVEGF-165) Cell Culture Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in E.coli. The biological activity is determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-8.0 ng/ml. MW: 38.231 D Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 87399.10 |
Vascular Endothelial Growth Factor-165, human recombinant (rHuVEGF-165) Cell Culture Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in E.coli. The biological activity is determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-8.0 ng/ml. MW: 38.231 D |
Biomol GmbH |
10 µg |
170 €
|
| 87399.2 |
Vascular Endothelial Growth Factor-165, human recombinant (rHuVEGF-165) Cell Culture Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in E.coli. The biological activity is determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-8.0 ng/ml. MW: 38.231 D |
Biomol GmbH |
2 µg |
66 €
|
| 87409.1 |
Vascular Endothelial Growth Factor-121-Sf9, human recombinant (rHuVEGF121-Sf9) Cell Culture Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in insect cells. The biological activity is determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 0.2-0.4 ng/ml. MW: 28.423 D Purity: >90% |
Biomol GmbH |
1 mg |
anfragen
|
| 87409.10 |
Vascular Endothelial Growth Factor-121-Sf9, human recombinant (rHuVEGF121-Sf9) Cell Culture Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in insect cells. The biological activity is determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 0.2-0.4 ng/ml. MW: 28.423 D |
Biomol GmbH |
10 µg |
170 €
|
| 87409.2 |
Vascular Endothelial Growth Factor-121-Sf9, human recombinant (rHuVEGF121-Sf9) Cell Culture Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in insect cells. The biological activity is determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 0.2-0.4 ng/ml. MW: 28.423 D |
Biomol GmbH |
2 µg |
66 €
|
| 94900.1 |
Vascular Endothelial Growth Factor, human recombinant (rHuVEGF-CHO) Cell biology studies Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in CHO cells as a double, glycosylated, polypeptide chain containing 165 amino acids. MW: 42.000 D Purity: >97% |
Biomol GmbH |
1 mg |
anfragen
|
| 94900.10 |
Vascular Endothelial Growth Factor, human recombinant (rHuVEGF-CHO) Cell biology studies Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in CHO cells as a double, glycosylated, polypeptide chain containing 165 amino acids. MW: 42.000 D |
Biomol GmbH |
10 µg |
170 €
|
| 94900.2 |
Vascular Endothelial Growth Factor, human recombinant (rHuVEGF-CHO) Cell biology studies Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in CHO cells as a double, glycosylated, polypeptide chain containing 165 amino acids. MW: 42.000 D |
Biomol GmbH |
2 µg |
66 €
|
| 95028.1 |
Vascular Endothelial Growth Factor, His Tag, human recombinant (rHuVEGF-His) Cell biology studies Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in E.coli as a non-glycosylated polypeptide chain containing 165 amino acids (fragment 5-169). MW: 38.200 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 95028.20 |
Vascular Endothelial Growth Factor, His Tag, human recombinant (rHuVEGF-His) Cell biology studies Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in E.coli as a non-glycosylated polypeptide chain containing 165 amino acids (fragment 5-169). MW: 38.200 D |
Biomol GmbH |
20 µg |
170 €
|
| 95028.5 |
Vascular Endothelial Growth Factor, His Tag, human recombinant (rHuVEGF-His) Cell biology studies Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in E.coli as a non-glycosylated polypeptide chain containing 165 amino acids (fragment 5-169). MW: 38.200 D |
Biomol GmbH |
5 µg |
66 €
|
| 97324.10 |
Vascular Endothelial Growth Factor-165, human recombinant (rHuVEGF-165) Cell Culture Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in HEK293 (Human Embryonic Kidney cell line). Double, glycosylated polypeptide chain containing 165 amino acids. Purity: >95% |
Biomol GmbH |
10 µg |
170 €
|
| 97324.2 |
Vascular Endothelial Growth Factor-165, human recombinant (rHuVEGF-165) Cell Culture Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in HEK293 (Human Embryonic Kidney cell line). Double, glycosylated polypeptide chain containing 165 amino acids. Purity: >95% |
Biomol GmbH |
2 µg |
66 €
|
| 99850.1 |
Vascular Endothelial Growth Factor, human recombinant (rHuVEGF-Yeast) Cell culture Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in Pichia pastoris as a double, glycosylated, polypeptide chain containing 165 amino acids. MW: 42.000 D Purity: >90% |
Biomol GmbH |
1 mg |
anfragen
|
| 99850.10 |
Vascular Endothelial Growth Factor, human recombinant (rHuVEGF-Yeast) Cell culture Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in Pichia pastoris as a double, glycosylated, polypeptide chain containing 165 amino acids. MW: 42.000 D |
Biomol GmbH |
10 µg |
170 €
|
| 99850.2 |
Vascular Endothelial Growth Factor, human recombinant (rHuVEGF-Yeast) Cell culture Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. (www.uniprot.org) Produced in Pichia pastoris as a double, glycosylated, polypeptide chain containing 165 amino acids. MW: 42.000 D |
Biomol GmbH |
2 µg |
66 €
|
| 99907.10 |
Vascular Endothelial Growth Factor 165 (VEGF165), human recombinant, plant based, bio-clean (rHuVEGF165) Bioassay, Cell culture Active protein produced in the endosperm tissue of barley grain. This production system uses barley endosperm storage cell which is characterised by its biochemically inert environment and lack of endotoxins. The barley endosperm tissue has a very low protease activity in comparison to most other cellular organisms, resulting in the unique protein storage function of the seed, that can maintain the proteins, including recombinant proteins, intact for years. The recombinant product is Aminal and Serum-free and therefore void of any human or animal viral contaminants that could jeopardize your cell culture. The purified recombinant protein carries no pyrogenic or pro-inflammatory contaminants. The Endotoxin level is less than 0.005ng per µg of recombinant protein (0.05EU/µg). Recombinant human VEGF165 contains 165 amino acids and a 16 a.a. histidine-based tag for a total length of 181 a.a. and has a predicted molecular mass of 20.9 kDa. As a result of glycosylation, the recombinant protein migrates with an apparent molecular mass of 30 kDa in SDS-PAGE. |
Biomol GmbH |
10 µg |
124 €
|
| 99907.100 |
Vascular Endothelial Growth Factor 165 (VEGF165), human recombinant, plant based, bio-clean (rHuVEGF165) Bioassay, Cell culture Active protein produced in the endosperm tissue of barley grain. This production system uses barley endosperm storage cell which is characterised by its biochemically inert environment and lack of endotoxins. The barley endosperm tissue has a very low protease activity in comparison to most other cellular organisms, resulting in the unique protein storage function of the seed, that can maintain the proteins, including recombinant proteins, intact for years. The recombinant product is Aminal and Serum-free and therefore void of any human or animal viral contaminants that could jeopardize your cell culture. The purified recombinant protein carries no pyrogenic or pro-inflammatory contaminants. The Endotoxin level is less than 0.005ng per µg of recombinant protein (0.05EU/µg). Recombinant human VEGF165 contains 165 amino acids and a 16 a.a. histidine-based tag for a total length of 181 a.a. and has a predicted molecular mass of 20.9 kDa. As a result of glycosylation, the recombinant protein migrates with an apparent molecular mass of 30 kDa in SDS-PAGE. |
Biomol GmbH |
100 µg |
660 €
|
| 99907.1000 |
Vascular Endothelial Growth Factor 165 (VEGF165), human recombinant, plant based, bio-clean (rHuVEGF165) Bioassay, Cell culture Active protein produced in the endosperm tissue of barley grain. This production system uses barley endosperm storage cell which is characterised by its biochemically inert environment and lack of endotoxins. The barley endosperm tissue has a very low protease activity in comparison to most other cellular organisms, resulting in the unique protein storage function of the seed, that can maintain the proteins, including recombinant proteins, intact for years. The recombinant product is Aminal and Serum-free and therefore void of any human or animal viral contaminants that could jeopardize your cell culture. The purified recombinant protein carries no pyrogenic or pro-inflammatory contaminants. The Endotoxin level is less than 0.005ng per µg of recombinant protein (0.05EU/µg). Recombinant human VEGF165 contains 165 amino acids and a 16 a.a. histidine-based tag for a total length of 181 a.a. and has a predicted molecular mass of 20.9 kDa. As a result of glycosylation, the recombinant protein migrates with an apparent molecular mass of 30 kDa in SDS-PAGE. |
Biomol GmbH |
1000 µg |
3149 €
|
| 08563.10 |
Insulin, human recombinant, Yeast Cell culture Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (www.uniprot.org) Produced in Yeast as a two chain, glycosylated polypeptide chain containing 51 amino acids MW: 5.807 D |
Biomol GmbH |
10 mg |
170 €
|
| 08563.2 |
Insulin, human recombinant, Yeast Cell culture Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (www.uniprot.org) Produced in Yeast as a two chain, glycosylated polypeptide chain containing 51 amino acids MW: 5.807 D |
Biomol GmbH |
2 mg |
66 €
|
| 87402.1 |
Insulin, human recombinant (rHuInsulin) Cell Culture Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (www.uniprot.org) Produced in E.coli. Two chain, non-glycosylated polypeptide chain containing 51 amino acids. Biomol's recombinant Insulin is fully biologically active when compared to WHO reference standard which is 28 units/mg. MW: 5.807 D |
Biomol GmbH |
1 g |
anfragen
|
| 87402.25 |
Insulin, human recombinant (rHuInsulin) Cell Culture Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (www.uniprot.org) Produced in E.coli. Two chain, non-glycosylated polypeptide chain containing 51 amino acids. Biomol's recombinant Insulin is fully biologically active when compared to WHO reference standard which is 28 units/mg. MW: 5.807 D |
Biomol GmbH |
25 mg |
151 €
|
| 87402.250 |
Insulin, human recombinant (rHuInsulin) Cell Culture Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (www.uniprot.org) Produced in E.coli. Two chain, non-glycosylated polypeptide chain containing 51 amino acids. Biomol's recombinant Insulin is fully biologically active when compared to WHO reference standard which is 28 units/mg. MW: 5.807 D |
Biomol GmbH |
250 mg |
415 €
|
| 50342.1 |
Insulin-Like Growth Factor-II, human recombinant (rHuIGF-2) Cell culture The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 67 amino acids. The ED50 is less then 1.0 ng/ml, corresponding to a specific activity of 106 IU/mg. MW: 7.505 D Purity: >97% |
Biomol GmbH |
1 mg |
anfragen
|
| 50342.10 |
Insulin-Like Growth Factor-II, human recombinant (rHuIGF-2) Cell culture The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 67 amino acids. The ED50 is less then 1.0 ng/ml, corresponding to a specific activity of 106 IU/mg. MW: 7.505 D |
Biomol GmbH |
10 µg |
66 €
|
| 50342.50 |
Insulin-Like Growth Factor-II, human recombinant (rHuIGF-2) Cell culture The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 67 amino acids. The ED50 is less then 1.0 ng/ml, corresponding to a specific activity of 106 IU/mg. MW: 7.505 D |
Biomol GmbH |
50 µg |
170 €
|
| 50361.1 |
Fibroblast Growth Factor basic, human recombinant (rHuFGF-basic) Cell culture The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 155 amino acids. The ED50, calculated by the dose-dependant proliferation of BAF3 cells expressing FGF receptors (measured by 3H-thymidine uptake) is <0.5 ng/ml. MW: 17.000 D Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 50361.10 |
Fibroblast Growth Factor basic, human recombinant (rHuFGF-basic) Cell culture The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 155 amino acids. The ED50, calculated by the dose-dependant proliferation of BAF3 cells expressing FGF receptors (measured by 3H-thymidine uptake) is <0.5 ng/ml. MW: 17.000 D |
Biomol GmbH |
10 µg |
66 €
|
| 50361.50 |
Fibroblast Growth Factor basic, human recombinant (rHuFGF-basic) Cell culture The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 155 amino acids. The ED50, calculated by the dose-dependant proliferation of BAF3 cells expressing FGF receptors (measured by 3H-thymidine uptake) is <0.5 ng/ml. MW: 17.000 D |
Biomol GmbH |
50 µg |
170 €
|
| 94957.1 |
Fibroblast Growth Factor basic, human recombinant (rHuFGF-basic-Sf9) Cell culture The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. (www.uniprot.org) Produced in Sf9 insect cells as a single, glycosylated, polypeptide chain containing 155 amino acids. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. MW: 17.353 D Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 94957.10 |
Fibroblast Growth Factor basic, human recombinant (rHuFGF-basic-Sf9) Cell culture The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. (www.uniprot.org) Produced in Sf9 insect cells as a single, glycosylated, polypeptide chain containing 155 amino acids. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. MW: 17.353 D |
Biomol GmbH |
10 µg |
170 €
|
| 94957.2 |
Fibroblast Growth Factor basic, human recombinant (rHuFGF-basic-Sf9) Cell culture The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. (www.uniprot.org) Produced in Sf9 insect cells as a single, glycosylated, polypeptide chain containing 155 amino acids. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. MW: 17.353 D |
Biomol GmbH |
2 µg |
66 €
|
| 97054.1 |
Fibroblast Growth Factor, basic (147 amino acids), human recombinant (rHuFGF-basic) Cell culture The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 147 amino acids Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 97054.10 |
Fibroblast Growth Factor, basic (147 amino acids), human recombinant (rHuFGF-basic) Cell culture The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 147 amino acids |
Biomol GmbH |
10 µg |
66 €
|
| 97054.50 |
Fibroblast Growth Factor, basic (147 amino acids), human recombinant (rHuFGF-basic) Cell culture The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 147 amino acids |
Biomol GmbH |
50 µg |
170 €
|
| 08545.1 |
Macrophage Migration Inhibitory Factor (MIF), active, human recombinant (rHuMIF) Cell biology studies Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 115 amino acids. MW: 12.500 D Purity: >97% |
Biomol GmbH |
1 mg |
anfragen
|
| 08545.10 |
Macrophage Migration Inhibitory Factor (MIF), active, human recombinant (rHuMIF) Cell biology studies Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 115 amino acids. MW: 12.500 D |
Biomol GmbH |
10 µg |
170 €
|
| 08545.2 |
Macrophage Migration Inhibitory Factor (MIF), active, human recombinant (rHuMIF) Cell biology studies Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 115 amino acids. MW: 12.500 D |
Biomol GmbH |
2 µg |
66 €
|
| 94975.1 |
Macrophage Migration Inhibitory Factor (NT), human recombinant, His Tag (rHuMIF-His-N) Cell culture Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. (www.uniprot.org) Produced in E.coli as a single, glycosylated, polypeptide chain having amino acids from 1-114. Macrophage migration inhibitory factor (MIF) has been identified to be secreted by the pituitary gland and the monocyte/macrophage and to play an important MW: 16.600 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 94975.25 |
Macrophage Migration Inhibitory Factor (NT), human recombinant, His Tag (rHuMIF-His-N) Cell culture Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. (www.uniprot.org) Produced in E.coli as a single, glycosylated, polypeptide chain having amino acids from 1-114. Macrophage migration inhibitory factor (MIF) has been identified to be secreted by the pituitary gland and the monocyte/macrophage and to play an important MW: 16.600 D |
Biomol GmbH |
25 µg |
170 €
|
| 94975.5 |
Macrophage Migration Inhibitory Factor (NT), human recombinant, His Tag (rHuMIF-His-N) Cell culture Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. (www.uniprot.org) Produced in E.coli as a single, glycosylated, polypeptide chain having amino acids from 1-114. Macrophage migration inhibitory factor (MIF) has been identified to be secreted by the pituitary gland and the monocyte/macrophage and to play an important MW: 16.600 D |
Biomol GmbH |
5 µg |
66 €
|
| 95053.1 |
Macrophage Migration Inhibitory Factor (CT), His Tag, human recombinant (rHuMIF-His-C) Cell biology studies Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. (www.uniprot.org) Produced in E.coli as a single, glycosylated, polypeptide chain containing 123 amino acids and fused to a His-tag at C-terminus. MW: 13.500 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 95053.25 |
Macrophage Migration Inhibitory Factor (CT), His Tag, human recombinant (rHuMIF-His-C) Cell biology studies Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. (www.uniprot.org) Produced in E.coli as a single, glycosylated, polypeptide chain containing 123 amino acids and fused to a His-tag at C-terminus. MW: 13.500 D |
Biomol GmbH |
25 µg |
170 €
|
| 95053.5 |
Macrophage Migration Inhibitory Factor (CT), His Tag, human recombinant (rHuMIF-His-C) Cell biology studies Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. (www.uniprot.org) Produced in E.coli as a single, glycosylated, polypeptide chain containing 123 amino acids and fused to a His-tag at C-terminus. MW: 13.500 D |
Biomol GmbH |
5 µg |
66 €
|
| 99848.1 |
Macrophage Migration Inhibitory Factor, human recombinant (rHuMIF) Cell culture Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 115 amino acids. MW: 12.000 D Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 99848.25 |
Macrophage Migration Inhibitory Factor, human recombinant (rHuMIF) Cell culture Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 115 amino acids. MW: 12.000 D |
Biomol GmbH |
25 µg |
170 €
|
| 99848.5 |
Macrophage Migration Inhibitory Factor, human recombinant (rHuMIF) Cell culture Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 115 amino acids. MW: 12.000 D |
Biomol GmbH |
5 µg |
66 €
|
| 94842.1 |
Stromal Cell-Derived Factor-1 alpha (CXCL12), human recombinant (rHuSDF-1a) Chemoattract. Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3-67) and thus to preserve activity on local sites. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the Lyn kinase. Stimulates migration of monocytes through its receptor, CXCR4, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through Lyn kinase. (www.uniprot.org) Produced in E.coli as a non-glycosylated, polypeptide chain containing 68 amino acids. CXCL12 is strongly chemotactic for lymphocytes and has been implicated as an important cell co-ordinator during development. MW: 8.004 D |
Biomol GmbH |
1 mg |
anfragen
|
| 94842.10 |
Stromal Cell-Derived Factor-1 alpha (CXCL12), human recombinant (rHuSDF-1a) Chemoattract. Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3-67) and thus to preserve activity on local sites. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the Lyn kinase. Stimulates migration of monocytes through its receptor, CXCR4, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through Lyn kinase. (www.uniprot.org) Produced in E.coli as a non-glycosylated, polypeptide chain containing 68 amino acids. CXCL12 is strongly chemotactic for lymphocytes and has been implicated as an important cell co-ordinator during development. MW: 8.004 D |
Biomol GmbH |
10 µg |
170 €
|
| 94842.2 |
Stromal Cell-Derived Factor-1 alpha (CXCL12), human recombinant (rHuSDF-1a) Chemoattract. Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3-67) and thus to preserve activity on local sites. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the Lyn kinase. Stimulates migration of monocytes through its receptor, CXCR4, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through Lyn kinase. (www.uniprot.org) Produced in E.coli as a non-glycosylated, polypeptide chain containing 68 amino acids. CXCL12 is strongly chemotactic for lymphocytes and has been implicated as an important cell co-ordinator during development. MW: 8.004 D |
Biomol GmbH |
2 µg |
66 €
|
| 94863.1 |
Stromal Cell-Derived Factor-1 beta (CXCL12), human recombinant (rHuSDF-1b) Chemoattract. Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3-67) and thus to preserve activity on local sites. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the Lyn kinase. Stimulates migration of monocytes through its receptor, CXCR4, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through Lyn kinase. (www.uniprot.org) Produced in E.coli as a non-glycosylated, polypeptide chain containing 72 amino acids. CXCL12 is strongly chemotactic for lymphocytes and has been implicated as an important cell co-ordinator during development. MW: 8.508 D Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 94863.10 |
Stromal Cell-Derived Factor-1 beta (CXCL12), human recombinant (rHuSDF-1b) Chemoattract. Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3-67) and thus to preserve activity on local sites. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the Lyn kinase. Stimulates migration of monocytes through its receptor, CXCR4, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through Lyn kinase. (www.uniprot.org) Produced in E.coli as a non-glycosylated, polypeptide chain containing 72 amino acids. CXCL12 is strongly chemotactic for lymphocytes and has been implicated as an important cell co-ordinator during development. MW: 8.508 D |
Biomol GmbH |
10 µg |
170 €
|
| 94863.2 |
Stromal Cell-Derived Factor-1 beta (CXCL12), human recombinant (rHuSDF-1b) Chemoattract. Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3-67) and thus to preserve activity on local sites. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the Lyn kinase. Stimulates migration of monocytes through its receptor, CXCR4, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through Lyn kinase. (www.uniprot.org) Produced in E.coli as a non-glycosylated, polypeptide chain containing 72 amino acids. CXCL12 is strongly chemotactic for lymphocytes and has been implicated as an important cell co-ordinator during development. MW: 8.508 D |
Biomol GmbH |
2 µg |
66 €
|
| 97330.1 |
Stromal Cell-Derived Factor-1 alpha (CXCL12), His-Tag, human recombinant (rHuSDF1a-His) Bioassay Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3-67) and thus to preserve activity on local sites. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the Lyn kinase. Stimulates migration of monocytes through its receptor, CXCR4, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through Lyn kinase. (www.uniprot.org) Recombinant human Stromal Cell-Derived Factor-1 alpha produced in E.coli is a non-glycosylated, polypeptide chain containing 78 amino acids, having a molecular mass of 9.2 kDa. The SDF-1a is fused to 10 amino acids His-Tag at N-terminus. SDF-1 (stromal cell-derived factor-1) is small cytokine belonging to the chemokine family that is officially designated Chemokine (C-X-C motif) ligand 12 (CXCL12). It is produced in two forms, SDF-1alpha/CXCL12a and SDF-1beta/CXCL12b, by alternate splicing of the same gene. Chemokines are characterized by the presence of four conserved cysteines, which form two disulfide bonds. The CXCL12 proteins belong to the group of CXC MW: 9.200 D |
Biomol GmbH |
1 mg |
anfragen
|
| 97330.10 |
Stromal Cell-Derived Factor-1 alpha (CXCL12), His-Tag, human recombinant (rHuSDF1a-His) Bioassay Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3-67) and thus to preserve activity on local sites. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the Lyn kinase. Stimulates migration of monocytes through its receptor, CXCR4, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through Lyn kinase. (www.uniprot.org) Recombinant human Stromal Cell-Derived Factor-1 alpha produced in E.coli is a non-glycosylated, polypeptide chain containing 78 amino acids, having a molecular mass of 9.2 kDa. The SDF-1a is fused to 10 amino acids His-Tag at N-terminus. SDF-1 (stromal cell-derived factor-1) is small cytokine belonging to the chemokine family that is officially designated Chemokine (C-X-C motif) ligand 12 (CXCL12). It is produced in two forms, SDF-1alpha/CXCL12a and SDF-1beta/CXCL12b, by alternate splicing of the same gene. Chemokines are characterized by the presence of four conserved cysteines, which form two disulfide bonds. The CXCL12 proteins belong to the group of CXC MW: 9.200 D |
Biomol GmbH |
10 µg |
170 €
|
| 97330.2 |
Stromal Cell-Derived Factor-1 alpha (CXCL12), His-Tag, human recombinant (rHuSDF1a-His) Bioassay Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3-67) and thus to preserve activity on local sites. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the Lyn kinase. Stimulates migration of monocytes through its receptor, CXCR4, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through Lyn kinase. (www.uniprot.org) Recombinant human Stromal Cell-Derived Factor-1 alpha produced in E.coli is a non-glycosylated, polypeptide chain containing 78 amino acids, having a molecular mass of 9.2 kDa. The SDF-1a is fused to 10 amino acids His-Tag at N-terminus. SDF-1 (stromal cell-derived factor-1) is small cytokine belonging to the chemokine family that is officially designated Chemokine (C-X-C motif) ligand 12 (CXCL12). It is produced in two forms, SDF-1alpha/CXCL12a and SDF-1beta/CXCL12b, by alternate splicing of the same gene. Chemokines are characterized by the presence of four conserved cysteines, which form two disulfide bonds. The CXCL12 proteins belong to the group of CXC MW: 9.200 D |
Biomol GmbH |
2 µg |
66 €
|
| 97338.1 |
Stromal Cell-Derived Factor-1 beta (CXCL12), His Tag, human recombinant (rHuSDF1b-His) Bioassay Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3-67) and thus to preserve activity on local sites. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the Lyn kinase. Stimulates migration of monocytes through its receptor, CXCR4, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through Lyn kinase. (www.uniprot.org) Recombinant human SDF-1 beta produced in E.coli is a non-glycosylated, polypeptide chain containing 93 amino acids (fragment 22-93) and having a molecular mass of 10.8 KDa. The SDF-1b is fused to 20 amino acid His-Tag at N-terminus. SDF-1 (stromal cell-derived factor-1) is small cytokine belonging to the chemokine family that is officially designated Chemokine (C-X-C motif) ligand 12 (CXCL12). It is produced in two forms, SDF-1alpha/CXCL12a and SDF-1beta/CXCL12b, by alternate splicing of the same gene. Chemokines are characterized by the presence of four conserved cysteines, which form two disulfide bonds. The CXCL12 proteins belong to the group of CXC chem MW: 10.800 D |
Biomol GmbH |
1 mg |
anfragen
|
| 97338.10 |
Stromal Cell-Derived Factor-1 beta (CXCL12), His Tag, human recombinant (rHuSDF1b-His) Bioassay Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3-67) and thus to preserve activity on local sites. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the Lyn kinase. Stimulates migration of monocytes through its receptor, CXCR4, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through Lyn kinase. (www.uniprot.org) Recombinant human SDF-1 beta produced in E.coli is a non-glycosylated, polypeptide chain containing 93 amino acids (fragment 22-93) and having a molecular mass of 10.8 KDa. The SDF-1b is fused to 20 amino acid His-Tag at N-terminus. SDF-1 (stromal cell-derived factor-1) is small cytokine belonging to the chemokine family that is officially designated Chemokine (C-X-C motif) ligand 12 (CXCL12). It is produced in two forms, SDF-1alpha/CXCL12a and SDF-1beta/CXCL12b, by alternate splicing of the same gene. Chemokines are characterized by the presence of four conserved cysteines, which form two disulfide bonds. The CXCL12 proteins belong to the group of CXC chem MW: 10.800 D |
Biomol GmbH |
10 µg |
170 €
|
| 97338.2 |
Stromal Cell-Derived Factor-1 beta (CXCL12), His Tag, human recombinant (rHuSDF1b-His) Bioassay Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3-67) and thus to preserve activity on local sites. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the Lyn kinase. Stimulates migration of monocytes through its receptor, CXCR4, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through Lyn kinase. (www.uniprot.org) Recombinant human SDF-1 beta produced in E.coli is a non-glycosylated, polypeptide chain containing 93 amino acids (fragment 22-93) and having a molecular mass of 10.8 KDa. The SDF-1b is fused to 20 amino acid His-Tag at N-terminus. SDF-1 (stromal cell-derived factor-1) is small cytokine belonging to the chemokine family that is officially designated Chemokine (C-X-C motif) ligand 12 (CXCL12). It is produced in two forms, SDF-1alpha/CXCL12a and SDF-1beta/CXCL12b, by alternate splicing of the same gene. Chemokines are characterized by the presence of four conserved cysteines, which form two disulfide bonds. The CXCL12 proteins belong to the group of CXC chem MW: 10.800 D |
Biomol GmbH |
2 µg |
66 €
|
| 50435.1 |
Tumor Necrosis Factor alpha, human recombinant (rHuTNF-a) Cell culture Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 158 amino acids. The ED50 as determined by the cytolysis of murine L929 cells in the presence of Actinomycin D is < 0.05ng/ml. MW: 17.484 D Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 50435.10 |
Tumor Necrosis Factor alpha, human recombinant (rHuTNF-a) Cell culture Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 158 amino acids. The ED50 as determined by the cytolysis of murine L929 cells in the presence of Actinomycin D is < 0.05ng/ml. MW: 17.484 D |
Biomol GmbH |
10 µg |
66 €
|
| 50435.50 |
Tumor Necrosis Factor alpha, human recombinant (rHuTNF-a) Cell culture Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 158 amino acids. The ED50 as determined by the cytolysis of murine L929 cells in the presence of Actinomycin D is < 0.05ng/ml. MW: 17.484 D |
Biomol GmbH |
50 µg |
170 €
|
| 94964.1 |
Tumor Necrosis Factor alpha Mutant/Variant, human recombinant (rHuTNF-a-M) Cell culture Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated polypeptide chain containing 151 amino acids. The mutant has an amino acid sequence deletion from amino acid 1-7, and the following amino acid substitutes Arg8, Lys9, Arg10 and Phe157 which is proven t MW: 16.598 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 94964.10 |
Tumor Necrosis Factor alpha Mutant/Variant, human recombinant (rHuTNF-a-M) Cell culture Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated polypeptide chain containing 151 amino acids. The mutant has an amino acid sequence deletion from amino acid 1-7, and the following amino acid substitutes Arg8, Lys9, Arg10 and Phe157 which is proven t MW: 16.598 D |
Biomol GmbH |
10 µg |
66 €
|
| 94964.50 |
Tumor Necrosis Factor alpha Mutant/Variant, human recombinant (rHuTNF-a-M) Cell culture Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated polypeptide chain containing 151 amino acids. The mutant has an amino acid sequence deletion from amino acid 1-7, and the following amino acid substitutes Arg8, Lys9, Arg10 and Phe157 which is proven t MW: 16.598 D |
Biomol GmbH |
50 µg |
170 €
|
| 95026.1 |
Tumor Necrosis Factor alpha, His Tag, human recombinant (rHuTNF-a-His) Cell biology studies Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 157 amino acids (fragment 77-233) with an amino-terminal hexahistidine tag. MW: 21.850 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 95026.10 |
Tumor Necrosis Factor alpha, His Tag, human recombinant (rHuTNF-a-His) Cell biology studies Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 157 amino acids (fragment 77-233) with an amino-terminal hexahistidine tag. MW: 21.850 D |
Biomol GmbH |
10 µg |
66 €
|
| 95026.50 |
Tumor Necrosis Factor alpha, His Tag, human recombinant (rHuTNF-a-His) Cell biology studies Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 157 amino acids (fragment 77-233) with an amino-terminal hexahistidine tag. MW: 21.850 D |
Biomol GmbH |
50 µg |
170 €
|
| 94920.1 |
Interferon Regulatory Factor-3, human recombinant (rHuIRF-3) WB, Bioassays Mediates interferon-stimulated response element (ISRE) promoter activation. Functions as a molecular switch for antiviral activity. DsRNA generated during the course of an viral infection leads to IRF3 phosphorylation on the C-terminal serine/threonine cluster. This induces a conformational change, leading to its dimerization, nuclear localization and association with CREB binding protein (CREBBP) to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of genes under the control of ISRE. The complex binds to the IE and PRDIII regions on the IFN-alpha and IFN-beta promoters respectively. IRF-3 does not have any transcription activation domains. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 111 amino acids (1-112). IRF-3 plays a crucial role in activation of innate immunity and inflammation in response to viral infection. MW: 13.000 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 94920.20 |
Interferon Regulatory Factor-3, human recombinant (rHuIRF-3) WB, Bioassays Mediates interferon-stimulated response element (ISRE) promoter activation. Functions as a molecular switch for antiviral activity. DsRNA generated during the course of an viral infection leads to IRF3 phosphorylation on the C-terminal serine/threonine cluster. This induces a conformational change, leading to its dimerization, nuclear localization and association with CREB binding protein (CREBBP) to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of genes under the control of ISRE. The complex binds to the IE and PRDIII regions on the IFN-alpha and IFN-beta promoters respectively. IRF-3 does not have any transcription activation domains. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 111 amino acids (1-112). IRF-3 plays a crucial role in activation of innate immunity and inflammation in response to viral infection. MW: 13.000 D |
Biomol GmbH |
20 µg |
175 €
|
| 94920.5 |
Interferon Regulatory Factor-3, human recombinant (rHuIRF-3) WB, Bioassays Mediates interferon-stimulated response element (ISRE) promoter activation. Functions as a molecular switch for antiviral activity. DsRNA generated during the course of an viral infection leads to IRF3 phosphorylation on the C-terminal serine/threonine cluster. This induces a conformational change, leading to its dimerization, nuclear localization and association with CREB binding protein (CREBBP) to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of genes under the control of ISRE. The complex binds to the IE and PRDIII regions on the IFN-alpha and IFN-beta promoters respectively. IRF-3 does not have any transcription activation domains. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 111 amino acids (1-112). IRF-3 plays a crucial role in activation of innate immunity and inflammation in response to viral infection. MW: 13.000 D |
Biomol GmbH |
5 µg |
68 €
|
| 97060.1 |
Galectin-1, human recombinant (rHuGAL-1) Cell culture May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 134 amino acids Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 97060.10 |
Galectin-1, human recombinant (rHuGAL-1) Cell culture May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 134 amino acids |
Biomol GmbH |
10 µg |
66 €
|
| 97060.50 |
Galectin-1, human recombinant (rHuGAL-1) Cell culture May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 134 amino acids |
Biomol GmbH |
50 µg |
170 €
|
| 94958.1 |
Cytotoxic T-Lymphocyte Associated Antigen-4/Fc Chimera, human recombinant (rHuCTLA-4) Cell culture Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. (www.uniprot.org) Produced in insect cells as a homodimeric, glycosylated, polypeptide chain. MW: 80.000 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 94958.25 |
Cytotoxic T-Lymphocyte Associated Antigen-4/Fc Chimera, human recombinant (rHuCTLA-4) Cell culture Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. (www.uniprot.org) Produced in insect cells as a homodimeric, glycosylated, polypeptide chain. MW: 80.000 D |
Biomol GmbH |
25 µg |
170 €
|
| 94958.5 |
Cytotoxic T-Lymphocyte Associated Antigen-4/Fc Chimera, human recombinant (rHuCTLA-4) Cell culture Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. (www.uniprot.org) Produced in insect cells as a homodimeric, glycosylated, polypeptide chain. MW: 80.000 D |
Biomol GmbH |
5 µg |
66 €
|
| 94843.1 |
Monocyte Chemotactic Protein-1/MCAF (CCL2), human recombinant (rHuMCP-1/MCAF) Chemoattract. Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. (www.uniprot.org) Produced in E.coli as a non-glycosylated, polypeptide chain containing 76 amino acids. CCL2 recruits immune cells, such as monocytes, to sites of tissue injury and infection. MW: 8.607 D |
Biomol GmbH |
1 mg |
anfragen
|
| 94843.20 |
Monocyte Chemotactic Protein-1/MCAF (CCL2), human recombinant (rHuMCP-1/MCAF) Chemoattract. Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. (www.uniprot.org) Produced in E.coli as a non-glycosylated, polypeptide chain containing 76 amino acids. CCL2 recruits immune cells, such as monocytes, to sites of tissue injury and infection. MW: 8.607 D |
Biomol GmbH |
20 µg |
170 €
|
| 94843.5 |
Monocyte Chemotactic Protein-1/MCAF (CCL2), human recombinant (rHuMCP-1/MCAF) Chemoattract. Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. (www.uniprot.org) Produced in E.coli as a non-glycosylated, polypeptide chain containing 76 amino acids. CCL2 recruits immune cells, such as monocytes, to sites of tissue injury and infection. MW: 8.607 D |
Biomol GmbH |
5 µg |
66 €
|
| 97335.1 |
Monocyte Chemotactic Protein-1/MCAF (CCL2), His Tag, human recombinant (rHuMCP1-His) Bioassay Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. (www.uniprot.org) Recombinant human MCP-1 also known as Monocyte Chemotactic and Activating Factor (MCAF) produced in E.coli is a non-glycosylated, polypeptide chain containing 97 amino acids (24-99) and having a molecular mass of 10.9 kDa. The MCP-1 is fused to 20 amino acids His-Tag at N-terminus. Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). It is found at the site of tooth eruption and bone degradation. In the bone, CCL2 is expressed by mature osteoclasts and osteoblasts and is under the control of nuclear factor kappaB (NFkappaB). CCL2 recruits immune cells, such as monocytes, to sites of tissue injury and infection. This chemokine is produced as a protein precursor containing signal peptide of 23 amino acids and a mature peptide of 76 amino acids. It is a monomeric polypeptide, with a molecular weight of approximately 13kDa. As with many other CC chemokines, CCL2 is located on chromosome 17 in humans. The cell surface receptors that bind CCL2 are CCR2 and CCR5. MW: 10.900 D |
Biomol GmbH |
1 mg |
anfragen
|
| 97335.10 |
Monocyte Chemotactic Protein-1/MCAF (CCL2), His Tag, human recombinant (rHuMCP1-His) Bioassay Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. (www.uniprot.org) Recombinant human MCP-1 also known as Monocyte Chemotactic and Activating Factor (MCAF) produced in E.coli is a non-glycosylated, polypeptide chain containing 97 amino acids (24-99) and having a molecular mass of 10.9 kDa. The MCP-1 is fused to 20 amino acids His-Tag at N-terminus. Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). It is found at the site of tooth eruption and bone degradation. In the bone, CCL2 is expressed by mature osteoclasts and osteoblasts and is under the control of nuclear factor kappaB (NFkappaB). CCL2 recruits immune cells, such as monocytes, to sites of tissue injury and infection. This chemokine is produced as a protein precursor containing signal peptide of 23 amino acids and a mature peptide of 76 amino acids. It is a monomeric polypeptide, with a molecular weight of approximately 13kDa. As with many other CC chemokines, CCL2 is located on chromosome 17 in humans. The cell surface receptors that bind CCL2 are CCR2 and CCR5. MW: 10.900 D |
Biomol GmbH |
10 µg |
66 €
|
| 97335.50 |
Monocyte Chemotactic Protein-1/MCAF (CCL2), His Tag, human recombinant (rHuMCP1-His) Bioassay Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. (www.uniprot.org) Recombinant human MCP-1 also known as Monocyte Chemotactic and Activating Factor (MCAF) produced in E.coli is a non-glycosylated, polypeptide chain containing 97 amino acids (24-99) and having a molecular mass of 10.9 kDa. The MCP-1 is fused to 20 amino acids His-Tag at N-terminus. Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). It is found at the site of tooth eruption and bone degradation. In the bone, CCL2 is expressed by mature osteoclasts and osteoblasts and is under the control of nuclear factor kappaB (NFkappaB). CCL2 recruits immune cells, such as monocytes, to sites of tissue injury and infection. This chemokine is produced as a protein precursor containing signal peptide of 23 amino acids and a mature peptide of 76 amino acids. It is a monomeric polypeptide, with a molecular weight of approximately 13kDa. As with many other CC chemokines, CCL2 is located on chromosome 17 in humans. The cell surface receptors that bind CCL2 are CCR2 and CCR5. MW: 10.900 D |
Biomol GmbH |
50 µg |
170 €
|
|
76861.10 |
Transforming Growth Factor beta1, human recombinant (rHuTGF-b1) Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. (www.uniprot.org) Produced in E.coli. The TGF-beta 1 is purified by standard chromatographic techniques and shows a 51 kDa band on SDS-PAGE (including tag). MW: 25.455 D |
Biomol GmbH |
10 µg |
170 €
|
|
76861.100 |
Transforming Growth Factor beta1, human recombinant (rHuTGF-b1) Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. (www.uniprot.org) Produced in E.coli. The TGF-beta 1 is purified by standard chromatographic techniques and shows a 51 kDa band on SDS-PAGE (including tag). MW: 25.455 D |
Biomol GmbH |
100 µg |
1320 €
|
|
76861.2 |
Transforming Growth Factor beta1, human recombinant (rHuTGF-b1) Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. (www.uniprot.org) Produced in E.coli. The TGF-beta 1 is purified by standard chromatographic techniques and shows a 51 kDa band on SDS-PAGE (including tag). MW: 25.455 D |
Biomol GmbH |
2 µg |
66 €
|
|
97215.1 |
Transforming Growth Factor beta1, human (HuTGF-beta1) Cell culture Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. (www.uniprot.org) Transforming growth factors beta (TGF Betas) mediate many cell-cell interactions that occur during embryonic development. Three TGFBetas have been identified in mammals. Purity: >97% |
Biomol GmbH |
1 mg |
anfragen
|
|
97215.1000 |
Transforming Growth Factor beta1, human (HuTGF-beta1) Cell culture Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. (www.uniprot.org) Transforming growth factors beta (TGF Betas) mediate many cell-cell interactions that occur during embryonic development. Three TGFBetas have been identified in mammals. |
Biomol GmbH |
1 µg |
528 €
|
|
97215.2500 |
Transforming Growth Factor beta1, human (HuTGF-beta1) Cell culture Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. (www.uniprot.org) Transforming growth factors beta (TGF Betas) mediate many cell-cell interactions that occur during embryonic development. Three TGFBetas have been identified in mammals. |
Biomol GmbH |
2500 ng |
1254 €
|
| 97286.1 |
Transforming Growth Factor-Beta 1, human recombinant, His Tag (rHuTGF-beta1) Bioassay Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. (www.uniprot.org) Human recombinant TGF-b 1 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 112 amino acids fragment (279-390) having a molecular weight of 17.3kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. Transforming growth factor betas (TGFBetas) mediate many cell-cell interactions that occur during embryonic development. Three TGFBetas have been identified in mammals. TGFBeta1, TGFBeta2 and TGFBeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. TGF-b 1 regulates the actions of numerous other growth factors involved in a variety of human diseases including renal disease, hepatic disease, heart failure and cardiomyopathies. Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 97286.10 |
Transforming Growth Factor-Beta 1, human recombinant, His Tag (rHuTGF-beta1) Bioassay Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. (www.uniprot.org) Human recombinant TGF-b 1 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 112 amino acids fragment (279-390) having a molecular weight of 17.3kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. Transforming growth factor betas (TGFBetas) mediate many cell-cell interactions that occur during embryonic development. Three TGFBetas have been identified in mammals. TGFBeta1, TGFBeta2 and TGFBeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. TGF-b 1 regulates the actions of numerous other growth factors involved in a variety of human diseases including renal disease, hepatic disease, heart failure and cardiomyopathies. Purity: >95% |
Biomol GmbH |
10 µg |
170 €
|
| 97286.2 |
Transforming Growth Factor-Beta 1, human recombinant, His Tag (rHuTGF-beta1) Bioassay Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. (www.uniprot.org) Human recombinant TGF-b 1 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 112 amino acids fragment (279-390) having a molecular weight of 17.3kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. Transforming growth factor betas (TGFBetas) mediate many cell-cell interactions that occur during embryonic development. Three TGFBetas have been identified in mammals. TGFBeta1, TGFBeta2 and TGFBeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. TGF-b 1 regulates the actions of numerous other growth factors involved in a variety of human diseases including renal disease, hepatic disease, heart failure and cardiomyopathies. Purity: >95% |
Biomol GmbH |
2 µg |
66 €
|
| 97293.1 |
Transforming Growth Factor-Beta 1 (113 amino acids), human recombinant (rHuTGF-b1) Bioassay Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. (www.uniprot.org) Human recombinant TGF-b 1 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 113 amino acids (fragment 279-390) and having a total molecular mass of 12.9 kDa. Transforming growth factor betas (TGFBetas) mediate many cell-cell interactions that occur during embryonic development. Three TGFBetas have been identified in mammals. TGFBeta1, TGFBeta2 and TGFBeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. MW: 12.900 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 97293.10 |
Transforming Growth Factor-Beta 1 (113 amino acids), human recombinant (rHuTGF-b1) Bioassay Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. (www.uniprot.org) Human recombinant TGF-b 1 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 113 amino acids (fragment 279-390) and having a total molecular mass of 12.9 kDa. Transforming growth factor betas (TGFBetas) mediate many cell-cell interactions that occur during embryonic development. Three TGFBetas have been identified in mammals. TGFBeta1, TGFBeta2 and TGFBeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. MW: 12.900 D Purity: >95% |
Biomol GmbH |
10 µg |
170 €
|
| 97293.2 |
Transforming Growth Factor-Beta 1 (113 amino acids), human recombinant (rHuTGF-b1) Bioassay Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. (www.uniprot.org) Human recombinant TGF-b 1 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 113 amino acids (fragment 279-390) and having a total molecular mass of 12.9 kDa. Transforming growth factor betas (TGFBetas) mediate many cell-cell interactions that occur during embryonic development. Three TGFBetas have been identified in mammals. TGFBeta1, TGFBeta2 and TGFBeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. MW: 12.900 D Purity: >95% |
Biomol GmbH |
2 µg |
66 €
|
| 97361.1 |
Transforming Growth Factor-Beta 1, HEK 293, human recombinant (rHuTGFb1-HEK) Cell Culture Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. (www.uniprot.org) Recombinant human TGFB1 produced in Human 293 cells is a homodimeric polypeptide chain containing 2 x 112 amino acids and having a total molecular mass of 25kDa. The TGFB1 is purified by proprietary chromatographic techniques. Transforming growth factor betas (TGFBetas) mediate many cell-cell interactions that occur during embryonic development. Three TGFBetas have been identified in mammals. TGFBeta1, TGFBeta2 and TGFBeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. MW: 25.000 D Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 97361.100 |
Transforming Growth Factor-Beta 1, HEK 293, human recombinant (rHuTGFb1-HEK) Cell Culture Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. (www.uniprot.org) Recombinant human TGFB1 produced in Human 293 cells is a homodimeric polypeptide chain containing 2 x 112 amino acids and having a total molecular mass of 25kDa. The TGFB1 is purified by proprietary chromatographic techniques. Transforming growth factor betas (TGFBetas) mediate many cell-cell interactions that occur during embryonic development. Three TGFBetas have been identified in mammals. TGFBeta1, TGFBeta2 and TGFBeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. MW: 25.000 D |
Biomol GmbH |
100 µg |
1980 €
|
| 97361.5 |
Transforming Growth Factor-Beta 1, HEK 293, human recombinant (rHuTGFb1-HEK) Cell Culture Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. (www.uniprot.org) Recombinant human TGFB1 produced in Human 293 cells is a homodimeric polypeptide chain containing 2 x 112 amino acids and having a total molecular mass of 25kDa. The TGFB1 is purified by proprietary chromatographic techniques. Transforming growth factor betas (TGFBetas) mediate many cell-cell interactions that occur during embryonic development. Three TGFBetas have been identified in mammals. TGFBeta1, TGFBeta2 and TGFBeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. MW: 25.000 D |
Biomol GmbH |
5 µg |
170 €
|
| 87383.1 |
Growth Hormone Binding Protein, human recombinant (rHuGHBP) Cell Culture Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity). (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 237 amino acids. Biomol's recombinant human growth hormone binding protein is fully biologically active when compared to WHO standard. MW: 28.107 D Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 87383.20 |
Growth Hormone Binding Protein, human recombinant (rHuGHBP) Cell Culture Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity). (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 237 amino acids. Biomol's recombinant human growth hormone binding protein is fully biologically active when compared to WHO standard. MW: 28.107 D |
Biomol GmbH |
20 µg |
170 €
|
| 87383.5 |
Growth Hormone Binding Protein, human recombinant (rHuGHBP) Cell Culture Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity). (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 237 amino acids. Biomol's recombinant human growth hormone binding protein is fully biologically active when compared to WHO standard. MW: 28.107 D |
Biomol GmbH |
5 µg |
66 €
|
| 52615.1 |
Brain Derived Neurotrophic Factor, human recombinant (rHuBDNF) Cell culture During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. (www.uniprot.org) Produced in E.coli. Homodimer, non-glycosylated polypeptide chain containing 2 x 119 amino acids. The ED50, calculated by the dose-dependant induction of ACHE (acetylcholine esterase) in rat basal forebrain primary septal culture is 50 ng/ml. MW: 27.000 D Purity: >96% |
Biomol GmbH |
1 mg |
anfragen
|
| 52615.10 |
Brain Derived Neurotrophic Factor, human recombinant (rHuBDNF) Cell culture During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. (www.uniprot.org) Produced in E.coli. Homodimer, non-glycosylated polypeptide chain containing 2 x 119 amino acids. The ED50, calculated by the dose-dependant induction of ACHE (acetylcholine esterase) in rat basal forebrain primary septal culture is 50 ng/ml. MW: 27.000 D |
Biomol GmbH |
10 µg |
170 €
|
| 52615.2 |
Brain Derived Neurotrophic Factor, human recombinant (rHuBDNF) Cell culture During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. (www.uniprot.org) Produced in E.coli. Homodimer, non-glycosylated polypeptide chain containing 2 x 119 amino acids. The ED50, calculated by the dose-dependant induction of ACHE (acetylcholine esterase) in rat basal forebrain primary septal culture is 50 ng/ml. MW: 27.000 D |
Biomol GmbH |
2 µg |
66 €
|
| 94927.1 |
CD4, soluble, human recombinant (rHusCD4) Cell culture Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. (www.uniprot.org) Produced in Baculovirus as a single, glycosylated polypeptide chain containing 365 amino acids. CD4 is a cell-surface glycoprotein found on the mature helper T cells and immature thymocytes, as well as on monocytes and macrophages. MW: 40.000 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 94927.10 |
CD4, soluble, human recombinant (rHusCD4) Cell culture Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. (www.uniprot.org) Produced in Baculovirus as a single, glycosylated polypeptide chain containing 365 amino acids. CD4 is a cell-surface glycoprotein found on the mature helper T cells and immature thymocytes, as well as on monocytes and macrophages. MW: 40.000 D |
Biomol GmbH |
10 µg |
175 €
|
| 94927.2 |
CD4, soluble, human recombinant (rHusCD4) Cell culture Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. (www.uniprot.org) Produced in Baculovirus as a single, glycosylated polypeptide chain containing 365 amino acids. CD4 is a cell-surface glycoprotein found on the mature helper T cells and immature thymocytes, as well as on monocytes and macrophages. MW: 40.000 D |
Biomol GmbH |
2 µg |
68 €
|
| 94934.1 |
CD4, amino acids 203-317, human recombinant (rHuCD4/203-317) WB, Protein Assay, Antibody Production Cytokine that binds to TNFRSF18/AITR/GITR. Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues. (www.uniprot.org) Produced in E.coli, encoding amino acids 203-317 of human CD4. |
Biomol GmbH |
1 mg |
anfragen
|
| 94934.20 |
CD4, amino acids 203-317, human recombinant (rHuCD4/203-317) WB, Protein Assay, Antibody Production Cytokine that binds to TNFRSF18/AITR/GITR. Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues. (www.uniprot.org) Produced in E.coli, encoding amino acids 203-317 of human CD4. |
Biomol GmbH |
20 µg |
175 €
|
| 94934.5 |
CD4, amino acids 203-317, human recombinant (rHuCD4/203-317) WB, Protein Assay, Antibody Production Cytokine that binds to TNFRSF18/AITR/GITR. Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues. (www.uniprot.org) Produced in E.coli, encoding amino acids 203-317 of human CD4. |
Biomol GmbH |
5 µg |
68 €
|
| 54592.100 |
Interleukin-1 Receptor Antagonist, human recombinant (rHuIL-1RA) Inflammation response blocking Inhibits the activity of IL-1 by binding to its receptor. Has no IL-1 like activity. (www.uniprot.org) Purity: >98% MW: 17.000 |
Biomol GmbH |
100 µg |
170 €
|
| 54592.1000 |
Interleukin-1 Receptor Antagonist, human recombinant (rHuIL-1RA) Inflammation response blocking Inhibits the activity of IL-1 by binding to its receptor. Has no IL-1 like activity. (www.uniprot.org) Purity: >98% MW: 17.000 |
Biomol GmbH |
1 mg |
anfragen
|
| 54592.20 |
Interleukin-1 Receptor Antagonist, human recombinant (rHuIL-1RA) Bioassay Inhibits the activity of IL-1 by binding to its receptor. Has no IL-1 like activity. (www.uniprot.org) MW: 17.000 |
Biomol GmbH |
20 µg |
66 €
|
| 95013.1 |
Interleukin-1 Receptor Antagonist, His Tag, human recombinant (rHuIL-1RA-His) Cell biology studies Inhibits the activity of IL-1 by binding to its receptor. Has no IL-1 like activity. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 152 amino acids (fragment 117-269) with an amino-terminal hexahistidine tag. MW: 17.000 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 95013.10 |
Interleukin-1 Receptor Antagonist, His Tag, human recombinant (rHuIL-1RA-His) Cell biology studies Inhibits the activity of IL-1 by binding to its receptor. Has no IL-1 like activity. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 152 amino acids (fragment 117-269) with an amino-terminal hexahistidine tag. MW: 17.000 D |
Biomol GmbH |
10 µg |
198 €
|
| 95013.50 |
Interleukin-1 Receptor Antagonist, His Tag, human recombinant (rHuIL-1RA-His) Cell biology studies Inhibits the activity of IL-1 by binding to its receptor. Has no IL-1 like activity. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 152 amino acids (fragment 117-269) with an amino-terminal hexahistidine tag. MW: 17.000 D |
Biomol GmbH |
50 µg |
661 €
|
| 97287.1 |
Tumor Necrosis Factor Receptor Type 1, human recombinant, His Tag (rHuTNFR1) Bioassay Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. (www.uniprot.org) Human recombinant TNFR1 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 161 amino acids fragment (41-201) having a molecular weight of 22.68kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. TNFR1 belongs to the TNF-receptor superfamily. TNFR1 is a receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. There are 2 types of soluble TNF receptors: sTNFR-I and sTNFR-II, which act to neutralize the biological activities of TNF alpha and TNF beta. The levels of these soluble receptors seem to increase as a result of shedding of the extracellular domains of the membrane bound receptors. TNF-a, TNFR1 and TNFR2 have roles in cellular differentiation. TNFR1 and TNFR2 function in cell type-specific renal injury. TNFR1 is capable of signaling both cell survival and apoptosis. TNFR1-induced apoptosis requires 2 sequential signaling complexes. TNFR1 is capable of activating NF-kappaB, mediate apoptosis, and function as a regulator of infl Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 97287.20 |
Tumor Necrosis Factor Receptor Type 1, human recombinant, His Tag (rHuTNFR1) Bioassay Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. (www.uniprot.org) Human recombinant TNFR1 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 161 amino acids fragment (41-201) having a molecular weight of 22.68kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. TNFR1 belongs to the TNF-receptor superfamily. TNFR1 is a receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. There are 2 types of soluble TNF receptors: sTNFR-I and sTNFR-II, which act to neutralize the biological activities of TNF alpha and TNF beta. The levels of these soluble receptors seem to increase as a result of shedding of the extracellular domains of the membrane bound receptors. TNF-a, TNFR1 and TNFR2 have roles in cellular differentiation. TNFR1 and TNFR2 function in cell type-specific renal injury. TNFR1 is capable of signaling both cell survival and apoptosis. TNFR1-induced apoptosis requires 2 sequential signaling complexes. TNFR1 is capable of activating NF-kappaB, mediate apoptosis, and function as a regulator of infl Purity: >95% |
Biomol GmbH |
20 µg |
170 €
|
| 97287.5 |
Tumor Necrosis Factor Receptor Type 1, human recombinant, His Tag (rHuTNFR1) Bioassay Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. (www.uniprot.org) Human recombinant TNFR1 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 161 amino acids fragment (41-201) having a molecular weight of 22.68kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. TNFR1 belongs to the TNF-receptor superfamily. TNFR1 is a receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. There are 2 types of soluble TNF receptors: sTNFR-I and sTNFR-II, which act to neutralize the biological activities of TNF alpha and TNF beta. The levels of these soluble receptors seem to increase as a result of shedding of the extracellular domains of the membrane bound receptors. TNF-a, TNFR1 and TNFR2 have roles in cellular differentiation. TNFR1 and TNFR2 function in cell type-specific renal injury. TNFR1 is capable of signaling both cell survival and apoptosis. TNFR1-induced apoptosis requires 2 sequential signaling complexes. TNFR1 is capable of activating NF-kappaB, mediate apoptosis, and function as a regulator of infl Purity: >95% |
Biomol GmbH |
5 µg |
66 €
|
| 97323.1 |
Tumor Necrosis Factor Receptor Type 1, human recombinant (rHuTNFR1) Bioassay Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. (www.uniprot.org) TNFR1 Human Recombinant produced in E.coli is a single, non-glycosylated, polypeptide chain containing 162 amino acids and having a total molecular mass of 18.2 kDa. TNFR1 Human Recombinant is purified by proprietary chromatographic techniques. TNFR1 belongs to the TNF-receptor superfamily. TNFR1 is a receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. There are 2 types of soluble TNF receptors: sTNFR-I and sTNFR-II, which act to neutralize the biological activities of TNF alpha and TNF beta. The levels of these soluble receptors seem to increase as a result of shedding of the extracellular domains of the membrane bound receptors. TNF-a, TNFR1 and TNFR2 have roles in cellular differentiation. TNFR1 and TNFR2 function in cell type-specific renal injury. TNFR1 is capable of signaling both cell survival and apoptosis. TNFR1-induced apoptosis requires 2 sequential signaling complexes. TNFR1 is capable of activating NF-kappaB, mediate apoptosis, and function as a regul MW: 18.200 D Purity: >97% |
Biomol GmbH |
1 mg |
anfragen
|
| 97323.20 |
Tumor Necrosis Factor Receptor Type 1, human recombinant (rHuTNFR1) Bioassay Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. (www.uniprot.org) TNFR1 Human Recombinant produced in E.coli is a single, non-glycosylated, polypeptide chain containing 162 amino acids and having a total molecular mass of 18.2 kDa. TNFR1 Human Recombinant is purified by proprietary chromatographic techniques. TNFR1 belongs to the TNF-receptor superfamily. TNFR1 is a receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. There are 2 types of soluble TNF receptors: sTNFR-I and sTNFR-II, which act to neutralize the biological activities of TNF alpha and TNF beta. The levels of these soluble receptors seem to increase as a result of shedding of the extracellular domains of the membrane bound receptors. TNF-a, TNFR1 and TNFR2 have roles in cellular differentiation. TNFR1 and TNFR2 function in cell type-specific renal injury. TNFR1 is capable of signaling both cell survival and apoptosis. TNFR1-induced apoptosis requires 2 sequential signaling complexes. TNFR1 is capable of activating NF-kappaB, mediate apoptosis, and function as a regul MW: 18.200 D Purity: >97% |
Biomol GmbH |
20 µg |
170 €
|
| 97323.5 |
Tumor Necrosis Factor Receptor Type 1, human recombinant (rHuTNFR1) Bioassay Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. (www.uniprot.org) TNFR1 Human Recombinant produced in E.coli is a single, non-glycosylated, polypeptide chain containing 162 amino acids and having a total molecular mass of 18.2 kDa. TNFR1 Human Recombinant is purified by proprietary chromatographic techniques. TNFR1 belongs to the TNF-receptor superfamily. TNFR1 is a receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. There are 2 types of soluble TNF receptors: sTNFR-I and sTNFR-II, which act to neutralize the biological activities of TNF alpha and TNF beta. The levels of these soluble receptors seem to increase as a result of shedding of the extracellular domains of the membrane bound receptors. TNF-a, TNFR1 and TNFR2 have roles in cellular differentiation. TNFR1 and TNFR2 function in cell type-specific renal injury. TNFR1 is capable of signaling both cell survival and apoptosis. TNFR1-induced apoptosis requires 2 sequential signaling complexes. TNFR1 is capable of activating NF-kappaB, mediate apoptosis, and function as a regul MW: 18.200 D Purity: >97% |
Biomol GmbH |
5 µg |
66 €
|
| 60530.1 |
Macrophage Colony Stimulating Factor, human recombinant (rHuM-CSF) Cell Culture Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. (www.uniprot.org) Recombinant Human M-CSF produced in E.coli is a disulfide linked homodimer, non-glycosylated, polypeptide chain containing 2 x 159 amino acids. MW: 37 kD Purity: > 95% |
Biomol GmbH |
1 mg |
anfragen
|
| 60530.10 |
Macrophage Colony Stimulating Factor, human recombinant (rHuM-CSF) Cell Culture Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. (www.uniprot.org) Recombinant Human M-CSF produced in E.coli is a disulfide linked homodimer, non-glycosylated, polypeptide chain containing 2 x 159 amino acids. MW: 37 kD |
Biomol GmbH |
10 µg |
170 €
|
| 60530.2 |
Macrophage Colony Stimulating Factor, human recombinant (rHuM-CSF) Cell Culture Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. (www.uniprot.org) Recombinant Human M-CSF produced in E.coli is a disulfide linked homodimer, non-glycosylated, polypeptide chain containing 2 x 159 amino acids. MW: 37 kD |
Biomol GmbH |
2 µg |
66 €
|
| 97239.1 |
Macrophage Colony Stimulating Factor (MCSF, CSF-1), human recombinant Cell culture Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. (www.uniprot.org) Produced in baculovirus as a disulfide linked homodimer, glycosylated, polypeptide chain containing 2 x 149 amino acids. MW: 42.000 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 97239.10 |
Macrophage Colony Stimulating Factor (MCSF, CSF-1), human recombinant Cell culture Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. (www.uniprot.org) Produced in baculovirus as a disulfide linked homodimer, glycosylated, polypeptide chain containing 2 x 149 amino acids. MW: 42.000 D Purity: >95% |
Biomol GmbH |
10 µg |
170 €
|
| 97239.2 |
Macrophage Colony Stimulating Factor (MCSF, CSF-1), human recombinant Cell culture Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. (www.uniprot.org) Produced in baculovirus as a disulfide linked homodimer, glycosylated, polypeptide chain containing 2 x 149 amino acids. MW: 42.000 D Purity: >95% |
Biomol GmbH |
2 µg |
66 €
|
| 97310.1 |
Macrophage Colony Stimulating Factor, human recombinant, His Tag (rHuMCSF) Bioassay Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. (www.uniprot.org) Human recombinant Macrophage Colony Stimulating Factor produced in E.coli is a single, non-glycosylated, polypeptide chain containing 179 amino acids (fragment 33-190) and having a total molecular mass of 20.7 kDa. MCSF is fused to a 20 amino acid His Tag at N-terminus. Granulocyte/Macrophage Colony-Stimulating Factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. MW: 20.700 D Purity: >90% |
Biomol GmbH |
1 mg |
anfragen
|
| 97310.25 |
Macrophage Colony Stimulating Factor, human recombinant, His Tag (rHuMCSF) Bioassay Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. (www.uniprot.org) Human recombinant Macrophage Colony Stimulating Factor produced in E.coli is a single, non-glycosylated, polypeptide chain containing 179 amino acids (fragment 33-190) and having a total molecular mass of 20.7 kDa. MCSF is fused to a 20 amino acid His Tag at N-terminus. Granulocyte/Macrophage Colony-Stimulating Factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. MW: 20.700 D Purity: >90% |
Biomol GmbH |
25 µg |
170 €
|
| 97310.5 |
Macrophage Colony Stimulating Factor, human recombinant, His Tag (rHuMCSF) Bioassay Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. (www.uniprot.org) Human recombinant Macrophage Colony Stimulating Factor produced in E.coli is a single, non-glycosylated, polypeptide chain containing 179 amino acids (fragment 33-190) and having a total molecular mass of 20.7 kDa. MCSF is fused to a 20 amino acid His Tag at N-terminus. Granulocyte/Macrophage Colony-Stimulating Factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. MW: 20.700 D Purity: >90% |
Biomol GmbH |
5 µg |
66 €
|
| 99906.10 |
Macrophage Colony Stimulating Factor (M-CSF), human recombinant, plant based, bio-clean (rHuM-CSF) Cell culture Active protein produced in the endosperm tissue of barley grain. This production system uses barley endosperm storage cell which is characterised by its biochemically inert environment and lack of endotoxins. The barley endosperm tissue has a very low protease activity in comparison to most other cellular organisms, resulting in the unique protein storage function of the seed, that can maintain the proteins, including recombinant proteins, intact for years. The recombinant product is Aminal and Serum-free and therefore void of any human or animal viral contaminants that could jeopardize your cell culture. The purified recombinant protein carries no pyrogenic or pro-inflammatory contaminants. The Endotoxin level is less than 0.005ng per µg of recombinant protein (0.05EU/µg). Recombinant human M-CSF contains 159 amino acids and a 16 a.a. histidine-based tag for a total length of 175 a.a. and has a predicted molecular mass of 20.7 kDa. The recombinant protein migrates with an apparent molecular mass of 21 kDa in SDS-PAGE. |
Biomol GmbH |
10 µg |
96 €
|
| 99906.100 |
Macrophage Colony Stimulating Factor (M-CSF), human recombinant, plant based, bio-clean (rHuM-CSF) Cell culture Active protein produced in the endosperm tissue of barley grain. This production system uses barley endosperm storage cell which is characterised by its biochemically inert environment and lack of endotoxins. The barley endosperm tissue has a very low protease activity in comparison to most other cellular organisms, resulting in the unique protein storage function of the seed, that can maintain the proteins, including recombinant proteins, intact for years. The recombinant product is Aminal and Serum-free and therefore void of any human or animal viral contaminants that could jeopardize your cell culture. The purified recombinant protein carries no pyrogenic or pro-inflammatory contaminants. The Endotoxin level is less than 0.005ng per µg of recombinant protein (0.05EU/µg). Recombinant human M-CSF contains 159 amino acids and a 16 a.a. histidine-based tag for a total length of 175 a.a. and has a predicted molecular mass of 20.7 kDa. The recombinant protein migrates with an apparent molecular mass of 21 kDa in SDS-PAGE. |
Biomol GmbH |
100 µg |
633 €
|
| 99906.1000 |
Macrophage Colony Stimulating Factor (M-CSF), human recombinant, plant based, bio-clean (rHuM-CSF) Cell culture Active protein produced in the endosperm tissue of barley grain. This production system uses barley endosperm storage cell which is characterised by its biochemically inert environment and lack of endotoxins. The barley endosperm tissue has a very low protease activity in comparison to most other cellular organisms, resulting in the unique protein storage function of the seed, that can maintain the proteins, including recombinant proteins, intact for years. The recombinant product is Aminal and Serum-free and therefore void of any human or animal viral contaminants that could jeopardize your cell culture. The purified recombinant protein carries no pyrogenic or pro-inflammatory contaminants. The Endotoxin level is less than 0.005ng per µg of recombinant protein (0.05EU/µg). Recombinant human M-CSF contains 159 amino acids and a 16 a.a. histidine-based tag for a total length of 175 a.a. and has a predicted molecular mass of 20.7 kDa. The recombinant protein migrates with an apparent molecular mass of 21 kDa in SDS-PAGE. |
Biomol GmbH |
1000 µg |
2984 €
|
| 99906.50 |
Macrophage Colony Stimulating Factor (M-CSF), human recombinant, plant based, bio-clean (rHuM-CSF) Cell culture Active protein produced in the endosperm tissue of barley grain. This production system uses barley endosperm storage cell which is characterised by its biochemically inert environment and lack of endotoxins. The barley endosperm tissue has a very low protease activity in comparison to most other cellular organisms, resulting in the unique protein storage function of the seed, that can maintain the proteins, including recombinant proteins, intact for years. The recombinant product is Aminal and Serum-free and therefore void of any human or animal viral contaminants that could jeopardize your cell culture. The purified recombinant protein carries no pyrogenic or pro-inflammatory contaminants. The Endotoxin level is less than 0.005ng per µg of recombinant protein (0.05EU/µg). Recombinant human M-CSF contains 159 amino acids and a 16 a.a. histidine-based tag for a total length of 175 a.a. and has a predicted molecular mass of 20.7 kDa. The recombinant protein migrates with an apparent molecular mass of 21 kDa in SDS-PAGE. |
Biomol GmbH |
50 µg |
424 €
|
| 94983.1 |
Interferon Regulatory Factor-1, His Tag, human recombinant (rHuIRF-1-His) WB, Bioassays Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Acts as a tumor suppressor. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 134 amino acids (1-114) with a His Tag of 20 amino acids. IRF-1 regulates gene expression critical to immune response, hematopoiesis and proliferation. MW: 15.000 D Purity: >90% |
Biomol GmbH |
1 mg |
anfragen
|
| 94983.20 |
Interferon Regulatory Factor-1, His Tag, human recombinant (rHuIRF-1-His) WB, Bioassays Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Acts as a tumor suppressor. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 134 amino acids (1-114) with a His Tag of 20 amino acids. IRF-1 regulates gene expression critical to immune response, hematopoiesis and proliferation. MW: 15.000 D |
Biomol GmbH |
20 µg |
175 €
|
| 94983.5 |
Interferon Regulatory Factor-1, His Tag, human recombinant (rHuIRF-1-His) WB, Bioassays Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Acts as a tumor suppressor. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 134 amino acids (1-114) with a His Tag of 20 amino acids. IRF-1 regulates gene expression critical to immune response, hematopoiesis and proliferation. MW: 15.000 D |
Biomol GmbH |
5 µg |
68 €
|
| 97295.1 |
Hepatoma-Derived Growth Factor, human recombinant (rHuHDGF) Bioassay Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor. (www.uniprot.org) Human recombinant HDGF protein is a single, non-glycosilated, polypeptide chain produced in E.coli, having a molecular weight of 11.5kDa and containing 100 amino acids. HDGF is a member of the hepatoma-derived growth factor family. HDGF plays a role as a secreted mitogen from the human hepatoma cell line Huh-7. HDGF is a nuclear targeted vascular smooth muscle cell mitogen as well as a heparin-binding protein that is greatly expressed in tumor cells where it stimulates proliferation. HDGF takes part in organ development and lung remodeling after injury by promoting proliferation of lung epithelial cells. HDGF plays a role in the carcinogenesis of gastric epithelial cells through promotion of cell proliferation by Erk1/2 activation. HDGF is linked with tumorigenesis and the growth of cancer. HDGF is a self-regulating factor connected with the prognosis of liver cancer, non-small cell lung cancer and pancreatic cancer. HDGF has proliferative, angiogenic, and neurotrophic activity. HDGF is a distinctive nuclear targeting growth factor that is vastly expressed in HCC cells and is a prognostic factor for HCC. MW: 11.500 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 97295.20 |
Hepatoma-Derived Growth Factor, human recombinant (rHuHDGF) Bioassay Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor. (www.uniprot.org) Human recombinant HDGF protein is a single, non-glycosilated, polypeptide chain produced in E.coli, having a molecular weight of 11.5kDa and containing 100 amino acids. HDGF is a member of the hepatoma-derived growth factor family. HDGF plays a role as a secreted mitogen from the human hepatoma cell line Huh-7. HDGF is a nuclear targeted vascular smooth muscle cell mitogen as well as a heparin-binding protein that is greatly expressed in tumor cells where it stimulates proliferation. HDGF takes part in organ development and lung remodeling after injury by promoting proliferation of lung epithelial cells. HDGF plays a role in the carcinogenesis of gastric epithelial cells through promotion of cell proliferation by Erk1/2 activation. HDGF is linked with tumorigenesis and the growth of cancer. HDGF is a self-regulating factor connected with the prognosis of liver cancer, non-small cell lung cancer and pancreatic cancer. HDGF has proliferative, angiogenic, and neurotrophic activity. HDGF is a distinctive nuclear targeting growth factor that is vastly expressed in HCC cells and is a prognostic factor for HCC. MW: 11.500 D Purity: >95% |
Biomol GmbH |
20 µg |
175 €
|
| 97295.5 |
Hepatoma-Derived Growth Factor, human recombinant (rHuHDGF) Bioassay Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor. (www.uniprot.org) Human recombinant HDGF protein is a single, non-glycosilated, polypeptide chain produced in E.coli, having a molecular weight of 11.5kDa and containing 100 amino acids. HDGF is a member of the hepatoma-derived growth factor family. HDGF plays a role as a secreted mitogen from the human hepatoma cell line Huh-7. HDGF is a nuclear targeted vascular smooth muscle cell mitogen as well as a heparin-binding protein that is greatly expressed in tumor cells where it stimulates proliferation. HDGF takes part in organ development and lung remodeling after injury by promoting proliferation of lung epithelial cells. HDGF plays a role in the carcinogenesis of gastric epithelial cells through promotion of cell proliferation by Erk1/2 activation. HDGF is linked with tumorigenesis and the growth of cancer. HDGF is a self-regulating factor connected with the prognosis of liver cancer, non-small cell lung cancer and pancreatic cancer. HDGF has proliferative, angiogenic, and neurotrophic activity. HDGF is a distinctive nuclear targeting growth factor that is vastly expressed in HCC cells and is a prognostic factor for HCC. MW: 11.500 D Purity: >95% |
Biomol GmbH |
5 µg |
68 €
|
| 94886.1 |
Interleukin-1 beta, human recombinant (rHuIL-1-beta) Cell biology studies Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 153 amino acids. MW: 17.000 D Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 94886.10 |
Interleukin-1 beta, human recombinant (rHuIL-1-beta) Cell biology studies Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 153 amino acids. MW: 17.000 D |
Biomol GmbH |
10 µg |
170 €
|
| 94886.2 |
Interleukin-1 beta, human recombinant (rHuIL-1-beta) Cell biology studies Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 153 amino acids. MW: 17.000 D |
Biomol GmbH |
2 µg |
66 €
|
| 95012.1 |
Interleukin-1 beta, His Tag, human recombinant (rHuIL-1-beta-His) Cell biology studies Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 153 amino acids (fragment 117-269) with an amino-terminal hexahistidine tag. Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 95012.20 |
Interleukin-1 beta, His Tag, human recombinant (rHuIL-1-beta-His) Cell biology studies Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 153 amino acids (fragment 117-269) with an amino-terminal hexahistidine tag. |
Biomol GmbH |
20 µg |
170 €
|
| 95012.5 |
Interleukin-1 beta, His Tag, human recombinant (rHuIL-1-beta-His) Cell biology studies Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 153 amino acids (fragment 117-269) with an amino-terminal hexahistidine tag. |
Biomol GmbH |
5 µg |
66 €
|
| 97290.1 |
Sonic HedgeHog, human recombinant (rHuSHH) Cell culture Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction (By similarity). (www.uniprot.org) Human recombinant Sonic HedgeHog produced in E.coli is a single, non-glycosylated polypeptide chain containing 175 amino acids and having a molecular mass of 19,683 Dalton. The Human Sonic Hedgehog is 99% homologous to the mouse gene. Cysteine at position 25 has been substituted with Ile. Recombinant Human Sonic Hedgehog is part of a small group of secreted proteins that are vital for development in both vertebrates and invertebrates. 3 mammalian hedgehog genes (sonic, desert, Indian) share about 60% homology. The Human Sonic Hedgehog is 99% homologous to the mouse gene. Sonic HedgeHog is a protein that is vital in guding the early embryo. It has been associated as the major inductive signal in patterning MW: 19.683 D Purity: >97% |
Biomol GmbH |
1 mg |
anfragen
|
| 97290.25 |
Sonic HedgeHog, human recombinant (rHuSHH) Cell culture Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction (By similarity). (www.uniprot.org) Human recombinant Sonic HedgeHog produced in E.coli is a single, non-glycosylated polypeptide chain containing 175 amino acids and having a molecular mass of 19,683 Dalton. The Human Sonic Hedgehog is 99% homologous to the mouse gene. Cysteine at position 25 has been substituted with Ile. Recombinant Human Sonic Hedgehog is part of a small group of secreted proteins that are vital for development in both vertebrates and invertebrates. 3 mammalian hedgehog genes (sonic, desert, Indian) share about 60% homology. The Human Sonic Hedgehog is 99% homologous to the mouse gene. Sonic HedgeHog is a protein that is vital in guding the early embryo. It has been associated as the major inductive signal in patterning MW: 19.683 D Purity: >97% |
Biomol GmbH |
25 µg |
170 €
|
| 97290.5 |
Sonic HedgeHog, human recombinant (rHuSHH) Cell culture Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction (By similarity). (www.uniprot.org) Human recombinant Sonic HedgeHog produced in E.coli is a single, non-glycosylated polypeptide chain containing 175 amino acids and having a molecular mass of 19,683 Dalton. The Human Sonic Hedgehog is 99% homologous to the mouse gene. Cysteine at position 25 has been substituted with Ile. Recombinant Human Sonic Hedgehog is part of a small group of secreted proteins that are vital for development in both vertebrates and invertebrates. 3 mammalian hedgehog genes (sonic, desert, Indian) share about 60% homology. The Human Sonic Hedgehog is 99% homologous to the mouse gene. Sonic HedgeHog is a protein that is vital in guding the early embryo. It has been associated as the major inductive signal in patterning MW: 19.683 D Purity: >97% |
Biomol GmbH |
5 µg |
66 €
|
| 95024.1 |
Platelet Derived Growth Factor-B, His Tag, human recombinant (rHuPDGF-B-His) Cell biology studies Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 109 amino acids (fragment 82-190) with an amino-terminal hexahistidine tag. Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 95024.20 |
Platelet Derived Growth Factor-B, His Tag, human recombinant (rHuPDGF-B-His) Cell biology studies Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 109 amino acids (fragment 82-190) with an amino-terminal hexahistidine tag. |
Biomol GmbH |
20 µg |
170 €
|
| 95024.5 |
Platelet Derived Growth Factor-B, His Tag, human recombinant (rHuPDGF-B-His) Cell biology studies Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 109 amino acids (fragment 82-190) with an amino-terminal hexahistidine tag. |
Biomol GmbH |
5 µg |
66 €
|
| 95033.1 |
Platelet Derived Growth Factor-BB, human recombinant (rHuPDGF-BB ) Cell biology studies Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. (www.uniprot.org) Produced in E.coli as a homodimeric, non-glycosylated, polypeptide chain containing 109 amino acids. MW: 24.300 D Purity: >97% |
Biomol GmbH |
1 mg |
anfragen
|
| 95033.10 |
Platelet Derived Growth Factor-BB, human recombinant (rHuPDGF-BB ) Cell biology studies Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. (www.uniprot.org) Produced in E.coli as a homodimeric, non-glycosylated, polypeptide chain containing 109 amino acids. MW: 24.300 D |
Biomol GmbH |
10 µg |
170 €
|
| 95033.2 |
Platelet Derived Growth Factor-BB, human recombinant (rHuPDGF-BB ) Cell biology studies Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. (www.uniprot.org) Produced in E.coli as a homodimeric, non-glycosylated, polypeptide chain containing 109 amino acids. MW: 24.300 D |
Biomol GmbH |
2 µg |
66 €
|
| 50436.1 |
Interleukin-6, human recombinant (rHuIL-6) Cell culture Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated polypeptide chain containing 184 amino acids. The ED50 as determined by the dose-dependant stimulation of murine 7TD1 cells is < 0.1 ng/ml. MW: 21.000 D Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 50436.20 |
Interleukin-6, human recombinant (rHuIL-6) Cell culture Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated polypeptide chain containing 184 amino acids. The ED50 as determined by the dose-dependant stimulation of murine 7TD1 cells is < 0.1 ng/ml. MW: 21.000 D |
Biomol GmbH |
20 µg |
170 €
|
| 50436.5 |
Interleukin-6, human recombinant (rHuIL-6) Cell culture Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated polypeptide chain containing 184 amino acids. The ED50 as determined by the dose-dependant stimulation of murine 7TD1 cells is < 0.1 ng/ml. MW: 21.000 D |
Biomol GmbH |
5 µg |
66 €
|
| 94907.1 |
Interleukin-6, human recombinant (rHuIL-6-CHO) Cell biology studies Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. (www.uniprot.org) Produced in CHO as a single, glycosylated polypeptide chain containing 185 amino acids. Purity: >97% |
Biomol GmbH |
1 mg |
anfragen
|
| 94907.10 |
Interleukin-6, human recombinant (rHuIL-6-CHO) Cell biology studies Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. (www.uniprot.org) Produced in CHO as a single, glycosylated polypeptide chain containing 185 amino acids. |
Biomol GmbH |
10 µg |
170 €
|
| 94907.2 |
Interleukin-6, human recombinant (rHuIL-6-CHO) Cell biology studies Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. (www.uniprot.org) Produced in CHO as a single, glycosylated polypeptide chain containing 185 amino acids. |
Biomol GmbH |
2 µg |
66 €
|
| 95016.1 |
Interleukin-6, His Tag, human recombinant (rHuIL-6-His) Cell biology studies Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 184 amino acids (fragment 29-211) with an amino-terminal hexahistidine tag. MW: 25.400 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 95016.10 |
Interleukin-6, His Tag, human recombinant (rHuIL-6-His) Cell biology studies Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 184 amino acids (fragment 29-211) with an amino-terminal hexahistidine tag. MW: 25.400 D |
Biomol GmbH |
10 µg |
66 €
|
| 95016.50 |
Interleukin-6, His Tag, human recombinant (rHuIL-6-His) Cell biology studies Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 184 amino acids (fragment 29-211) with an amino-terminal hexahistidine tag. MW: 25.400 D |
Biomol GmbH |
50 µg |
170 €
|
| 99866.10 |
Interleukin-6, active, His Tag, human recombinant (rHuIL-6-His), plant based, bio-clean Cell culture, WB Recombinant human Interleukin-6 contains a 10-His-tag at the N-terminal end, is produced by transient expression in non-transgenic plants and is purified by sequential chromatography (FPLC). This product contains no animal-derived components or impurities. The specific activity is determined by the dose-dependent stimulation of the proliferation of human TF-1 cells (human erytroleukemic indicator cell line). Recombinant human IL-6 is an important pro-inflammatory and anti-inflammatory cytokine expressed by many types cell including: T and B cells, macrophages, endothelial cells, fibroblasts, monocytes, keratinocytes and certain tumor cells. It is a multifunctional cytokine that modulates several physiologic processes such as haematopoiesis, stimulation of immunoglobulin synthesis, maturation and activation of B cells, differentiation of T lymphocytes and regulation of the hepatic acute-phase response. IL-6 is also produced in muscle, is discharged into the bloodstream after muscle contraction and acts increasing the breakdown of fats and improving insulin resistance. IL-6 induces signalling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6 R) and a signal transducing subunit (gp130). Purity: >97% |
Biomol GmbH |
10 µg |
105 €
|
| 99866.20 |
Interleukin-6, active, His Tag, human recombinant (rHuIL-6-His), plant based, bio-clean Cell culture, WB Recombinant human Interleukin-6 contains a 10-His-tag at the N-terminal end, is produced by transient expression in non-transgenic plants and is purified by sequential chromatography (FPLC). This product contains no animal-derived components or impurities. The specific activity is determined by the dose-dependent stimulation of the proliferation of human TF-1 cells (human erytroleukemic indicator cell line). Recombinant human IL-6 is an important pro-inflammatory and anti-inflammatory cytokine expressed by many types cell including: T and B cells, macrophages, endothelial cells, fibroblasts, monocytes, keratinocytes and certain tumor cells. It is a multifunctional cytokine that modulates several physiologic processes such as haematopoiesis, stimulation of immunoglobulin synthesis, maturation and activation of B cells, differentiation of T lymphocytes and regulation of the hepatic acute-phase response. IL-6 is also produced in muscle, is discharged into the bloodstream after muscle contraction and acts increasing the breakdown of fats and improving insulin resistance. IL-6 induces signalling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6 R) and a signal transducing subunit (gp130). Purity: >97% |
Biomol GmbH |
20 µg |
156 €
|
| 99866.5 |
Interleukin-6, active, His Tag, human recombinant (rHuIL-6-His), plant based, bio-clean Cell culture, WB Recombinant human Interleukin-6 contains a 10-His-tag at the N-terminal end, is produced by transient expression in non-transgenic plants and is purified by sequential chromatography (FPLC). This product contains no animal-derived components or impurities. The specific activity is determined by the dose-dependent stimulation of the proliferation of human TF-1 cells (human erytroleukemic indicator cell line). Recombinant human IL-6 is an important pro-inflammatory and anti-inflammatory cytokine expressed by many types cell including: T and B cells, macrophages, endothelial cells, fibroblasts, monocytes, keratinocytes and certain tumor cells. It is a multifunctional cytokine that modulates several physiologic processes such as haematopoiesis, stimulation of immunoglobulin synthesis, maturation and activation of B cells, differentiation of T lymphocytes and regulation of the hepatic acute-phase response. IL-6 is also produced in muscle, is discharged into the bloodstream after muscle contraction and acts increasing the breakdown of fats and improving insulin resistance. IL-6 induces signalling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6 R) and a signal transducing subunit (gp130). Purity: >97% |
Biomol GmbH |
5 µg |
65 €
|
| 99866.50 |
Interleukin-6, active, His Tag, human recombinant (rHuIL-6-His), plant based, bio-clean Cell culture, WB Recombinant human Interleukin-6 contains a 10-His-tag at the N-terminal end, is produced by transient expression in non-transgenic plants and is purified by sequential chromatography (FPLC). This product contains no animal-derived components or impurities. The specific activity is determined by the dose-dependent stimulation of the proliferation of human TF-1 cells (human erytroleukemic indicator cell line). Recombinant human IL-6 is an important pro-inflammatory and anti-inflammatory cytokine expressed by many types cell including: T and B cells, macrophages, endothelial cells, fibroblasts, monocytes, keratinocytes and certain tumor cells. It is a multifunctional cytokine that modulates several physiologic processes such as haematopoiesis, stimulation of immunoglobulin synthesis, maturation and activation of B cells, differentiation of T lymphocytes and regulation of the hepatic acute-phase response. IL-6 is also produced in muscle, is discharged into the bloodstream after muscle contraction and acts increasing the breakdown of fats and improving insulin resistance. IL-6 induces signalling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6 R) and a signal transducing subunit (gp130). Purity: >97% |
Biomol GmbH |
50 µg |
286 €
|
| 97186.1 |
PEDF (Pigment Epithelium Derived Factor), FLAG Tag, human recombinant (HEK293) (rHuPEDF-FLAG) Bioassays Neurotrophic protein. induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. (www.uniprot.org) Produced in HEK293 as a single, glycosylated, polypeptide chain containing 410 amino acids and having a N-terminal FLAG Tag Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 97186.10 |
PEDF (Pigment Epithelium Derived Factor), FLAG Tag, human recombinant (HEK293) (rHuPEDF-FLAG) Bioassays Neurotrophic protein. induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. (www.uniprot.org) Produced in HEK293 as a single, glycosylated, polypeptide chain containing 410 amino acids and having a N-terminal FLAG Tag |
Biomol GmbH |
10 µg |
170 €
|
| 97186.2 |
PEDF (Pigment Epithelium Derived Factor), FLAG Tag, human recombinant (HEK293) (rHuPEDF-FLAG) Bioassays Neurotrophic protein. induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. (www.uniprot.org) Produced in HEK293 as a single, glycosylated, polypeptide chain containing 410 amino acids and having a N-terminal FLAG Tag |
Biomol GmbH |
2 µg |
66 €
|
| 97200.1 |
PEDF (Pigment Epithelium Derived Factor), human recombinant (rHuPEDF-His) Bioassays Neurotrophic protein. induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 413 amino acids and having a N-terminal His Tag Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 97200.20 |
PEDF (Pigment Epithelium Derived Factor), human recombinant (rHuPEDF-His) Bioassays Neurotrophic protein. induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 413 amino acids and having a N-terminal His Tag |
Biomol GmbH |
20 µg |
170 €
|
| 97200.5 |
PEDF (Pigment Epithelium Derived Factor), human recombinant (rHuPEDF-His) Bioassays Neurotrophic protein. induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 413 amino acids and having a N-terminal His Tag |
Biomol GmbH |
5 µg |
66 €
|
| 99853.1 |
PEDF (Pigment Epithelium-Derived Factor), human recombinant (rHuPEDF) Bioassays Neurotrophic protein. induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 400 amino acids. MW: 44.500 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 99853.20 |
PEDF (Pigment Epithelium-Derived Factor), human recombinant (rHuPEDF) Bioassays Neurotrophic protein. induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 400 amino acids. MW: 44.500 D |
Biomol GmbH |
20 µg |
170 €
|
| 99853.5 |
PEDF (Pigment Epithelium-Derived Factor), human recombinant (rHuPEDF) Bioassays Neurotrophic protein. induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 400 amino acids. MW: 44.500 D |
Biomol GmbH |
5 µg |
66 €
|
| 97289.1 |
Serum Amyloid A, human recombinant, His Tag (rHuSAA1) Bioassay Major acute phase reactant. Apolipoprotein of the HDL complex. (www.uniprot.org) Human recombinant SAA1 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 125 amino acids (fragment 19-122) and having a total molecular mass of 13.9 kDa. SAA1 is fused to 20 amino acid His Tag at N-terminus. SAA1 protein is an acute phase apolipoprotein reactant which is produced mostly by hepatocytes and under regulation of inflammatory cytokines. SAA1 (Serum amyloid A1) protein is produced mainly in the liver and circulates in low levels in the blood. The SAA1 seems to have a role in the immune system. SAA1 protein levels increase in the blood and other tissues under conditions of inflammation. SAA1 may facilitate the repair of injured tissues, it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. SAA1 also functions as an apolipoprotein of the HDL complex.Elevated levels of SAA1 ultimately affect secondary amyloidosis, extracellular amassing of amyloid fibrils, resulting from a circulating precursor, in a variety of tissues and organs. The most widespread type of amyloidosis appears secondary to chronic inflammatory disease, mainly rheumatoid arthritis. MW: 13.900 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 97289.10 |
Serum Amyloid A, human recombinant, His Tag (rHuSAA1) Bioassay Major acute phase reactant. Apolipoprotein of the HDL complex. (www.uniprot.org) Human recombinant SAA1 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 125 amino acids (fragment 19-122) and having a total molecular mass of 13.9 kDa. SAA1 is fused to 20 amino acid His Tag at N-terminus. SAA1 protein is an acute phase apolipoprotein reactant which is produced mostly by hepatocytes and under regulation of inflammatory cytokines. SAA1 (Serum amyloid A1) protein is produced mainly in the liver and circulates in low levels in the blood. The SAA1 seems to have a role in the immune system. SAA1 protein levels increase in the blood and other tissues under conditions of inflammation. SAA1 may facilitate the repair of injured tissues, it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. SAA1 also functions as an apolipoprotein of the HDL complex.Elevated levels of SAA1 ultimately affect secondary amyloidosis, extracellular amassing of amyloid fibrils, resulting from a circulating precursor, in a variety of tissues and organs. The most widespread type of amyloidosis appears secondary to chronic inflammatory disease, mainly rheumatoid arthritis. MW: 13.900 D Purity: >95% |
Biomol GmbH |
10 µg |
66 €
|
| 97289.50 |
Serum Amyloid A, human recombinant, His Tag (rHuSAA1) Bioassay Major acute phase reactant. Apolipoprotein of the HDL complex. (www.uniprot.org) Human recombinant SAA1 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 125 amino acids (fragment 19-122) and having a total molecular mass of 13.9 kDa. SAA1 is fused to 20 amino acid His Tag at N-terminus. SAA1 protein is an acute phase apolipoprotein reactant which is produced mostly by hepatocytes and under regulation of inflammatory cytokines. SAA1 (Serum amyloid A1) protein is produced mainly in the liver and circulates in low levels in the blood. The SAA1 seems to have a role in the immune system. SAA1 protein levels increase in the blood and other tissues under conditions of inflammation. SAA1 may facilitate the repair of injured tissues, it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. SAA1 also functions as an apolipoprotein of the HDL complex.Elevated levels of SAA1 ultimately affect secondary amyloidosis, extracellular amassing of amyloid fibrils, resulting from a circulating precursor, in a variety of tissues and organs. The most widespread type of amyloidosis appears secondary to chronic inflammatory disease, mainly rheumatoid arthritis. MW: 13.900 D Purity: >95% |
Biomol GmbH |
50 µg |
170 €
|
| 94844.1 |
Neutrophil Activating Protein-2 (CXCL7), human recombinant (rHuNAP-2) Chemoattract. LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation. (www.uniprot.org) Produced in E.coli as a non-glycosylated, polypeptide chain containing 70 amino acids. Released from activated platelets it stimulates various processes including mitogenesis, synthesis of extracellular matrix, glucose metabolism etc. MW: 7.609 D |
Biomol GmbH |
1 mg |
anfragen
|
| 94844.10 |
Neutrophil Activating Protein-2 (CXCL7), human recombinant (rHuNAP-2) Chemoattract. LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation. (www.uniprot.org) Produced in E.coli as a non-glycosylated, polypeptide chain containing 70 amino acids. Released from activated platelets it stimulates various processes including mitogenesis, synthesis of extracellular matrix, glucose metabolism etc. MW: 7.609 D |
Biomol GmbH |
10 µg |
170 €
|
| 94844.2 |
Neutrophil Activating Protein-2 (CXCL7), human recombinant (rHuNAP-2) Chemoattract. LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation. (www.uniprot.org) Produced in E.coli as a non-glycosylated, polypeptide chain containing 70 amino acids. Released from activated platelets it stimulates various processes including mitogenesis, synthesis of extracellular matrix, glucose metabolism etc. MW: 7.609 D |
Biomol GmbH |
2 µg |
66 €
|
| 50356.1 |
Insulin-Like Growth Factor-I, human recombinant (rHuIGF-1) Cell culture The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 70 amino acids. The ED50, calculated by the dose-dependant proliferation of murine BALBC 3T3 cells (measured by H-thymidine uptake) is < 1.0 ng/ml. MW: 7.649 D Purity: >95% |
Biomol GmbH |
1 mg |
358 €
|
| 50356.100 |
Insulin-Like Growth Factor-I, human recombinant (rHuIGF-1) Cell culture The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 70 amino acids. The ED50, calculated by the dose-dependant proliferation of murine BALBC 3T3 cells (measured by H-thymidine uptake) is < 1.0 ng/ml. MW: 7.649 D |
Biomol GmbH |
100 µg |
170 €
|
| 50356.20 |
Insulin-Like Growth Factor-I, human recombinant (rHuIGF-1) Cell culture The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 70 amino acids. The ED50, calculated by the dose-dependant proliferation of murine BALBC 3T3 cells (measured by H-thymidine uptake) is < 1.0 ng/ml. MW: 7.649 D Purity: >95% |
Biomol GmbH |
20 µg |
66 €
|
| 95050.1 |
Insulin Like Growth Factor-I Des (1-3), human recombinant (rHuIGF-I des1-3) Cell biology studies The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 67 amino acids. MW: 7.372 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 95050.100 |
Insulin Like Growth Factor-I Des (1-3), human recombinant (rHuIGF-I des1-3) Cell biology studies The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 67 amino acids. MW: 7.372 D |
Biomol GmbH |
100 µg |
170 €
|
| 95050.20 |
Insulin Like Growth Factor-I Des (1-3), human recombinant (rHuIGF-I des1-3) Cell biology studies The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 67 amino acids. MW: 7.372 D |
Biomol GmbH |
20 µg |
66 €
|
| 97305.1 |
Insulin-Like Growth Factor 1, human recombinant, GST Tag (rHuIGF1) Bioassay The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. (www.uniprot.org) Human recombinant IGF1 produced in E.coli is a single, non-glycosylated, polypeptide chain fused to a GST tag. The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH, MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed sulfation factor, which later became known as somatomedin (Daughaday et al., 1972). Three main somatomedins have been characterized, somatomedin C (IGF1), somatomedin A (IGF2, MIM 147470), and somatomedin B (MIM 193190) (Rotwein, 1986, Rosenfeld, 2003). |
Biomol GmbH |
1 mg |
anfragen
|
| 97305.10 |
Insulin-Like Growth Factor 1, human recombinant, GST Tag (rHuIGF1) Bioassay The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. (www.uniprot.org) Human recombinant IGF1 produced in E.coli is a single, non-glycosylated, polypeptide chain fused to a GST tag. The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH, MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed sulfation factor, which later became known as somatomedin (Daughaday et al., 1972). Three main somatomedins have been characterized, somatomedin C (IGF1), somatomedin A (IGF2, MIM 147470), and somatomedin B (MIM 193190) (Rotwein, 1986, Rosenfeld, 2003). |
Biomol GmbH |
10 µg |
735 €
|
| 97305.2 |
Insulin-Like Growth Factor 1, human recombinant, GST Tag (rHuIGF1) Bioassay The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. (www.uniprot.org) Human recombinant IGF1 produced in E.coli is a single, non-glycosylated, polypeptide chain fused to a GST tag. The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH, MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed sulfation factor, which later became known as somatomedin (Daughaday et al., 1972). Three main somatomedins have been characterized, somatomedin C (IGF1), somatomedin A (IGF2, MIM 147470), and somatomedin B (MIM 193190) (Rotwein, 1986, Rosenfeld, 2003). |
Biomol GmbH |
2 µg |
264 €
|
| 97305.5 |
Insulin-Like Growth Factor 1, human recombinant, GST Tag (rHuIGF1) Bioassay The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. (www.uniprot.org) Human recombinant IGF1 produced in E.coli is a single, non-glycosylated, polypeptide chain fused to a GST tag. The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH, MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed sulfation factor, which later became known as somatomedin (Daughaday et al., 1972). Three main somatomedins have been characterized, somatomedin C (IGF1), somatomedin A (IGF2, MIM 147470), and somatomedin B (MIM 193190) (Rotwein, 1986, Rosenfeld, 2003). |
Biomol GmbH |
5 µg |
399 €
|
| 94893.1 |
Hepatocyte Growth Factor, human recombinant (rHuHGF) Cell culture HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity. (www.uniprot.org) Produced in Baculovirus as a heterodimer, non-glycosylated, polypeptide chain consisting an a-chain of 463 amino acids and a-chain of 234. Hepatocyte Growth Factor (HGF) is a multifunctional growth factor which regulates both cell growth and cell mot MW: 80.017 D Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 94893.10 |
Hepatocyte Growth Factor, human recombinant (rHuHGF) Cell culture HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity. (www.uniprot.org) Produced in Baculovirus as a heterodimer, non-glycosylated, polypeptide chain consisting an a-chain of 463 amino acids and a-chain of 234. Hepatocyte Growth Factor (HGF) is a multifunctional growth factor which regulates both cell growth and cell mot MW: 80.017 D |
Biomol GmbH |
10 µg |
170 €
|
| 94893.2 |
Hepatocyte Growth Factor, human recombinant (rHuHGF) Cell culture HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity. (www.uniprot.org) Produced in Baculovirus as a heterodimer, non-glycosylated, polypeptide chain consisting an a-chain of 463 amino acids and a-chain of 234. Hepatocyte Growth Factor (HGF) is a multifunctional growth factor which regulates both cell growth and cell mot MW: 80.017 D |
Biomol GmbH |
2 µg |
66 €
|
| 94897.1 |
Hepatocyte Growth Factor, human recombinant (rHuHGF-CHO) Cell biology studies HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity. (www.uniprot.org) Produced in CHO as a heterodimer, non-glycosylated, polypeptide chain consisting an alpha-chain of 463 amino acids and beta-chain of 234. MW: 80.017 D Purity: >97% |
Biomol GmbH |
1 mg |
anfragen
|
| 94897.10 |
Hepatocyte Growth Factor, human recombinant (rHuHGF-CHO) Cell biology studies HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity. (www.uniprot.org) Produced in CHO as a heterodimer, non-glycosylated, polypeptide chain consisting an alpha-chain of 463 amino acids and beta-chain of 234. MW: 80.017 D |
Biomol GmbH |
10 µg |
170 €
|
| 94897.2 |
Hepatocyte Growth Factor, human recombinant (rHuHGF-CHO) Cell biology studies HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity. (www.uniprot.org) Produced in CHO as a heterodimer, non-glycosylated, polypeptide chain consisting an alpha-chain of 463 amino acids and beta-chain of 234. MW: 80.017 D |
Biomol GmbH |
2 µg |
66 €
|
| 97278.1 |
Hepatocyte Growth Factor A Chain, human recombinant, His Tag (rHuHGFA) Bioassay HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity. (www.uniprot.org) Human recombinant HGF-A produced in E.coli is a single, non-glycosylated, polypeptide chain containing 463 amino acids fragment (32-494) having a molecular weight of 69kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. Hepatocyte Growth Factor (HGF) is a multifunctional growth factor which regulates both cell growth and cell motility. It exerts a strong mitogenic effect on hepatocytes and primary epithelial cells. HGF synergizes with Interleukin-3 and GM-CSF to stimulate colony formation of hematopoietic progenitor cells in vitro and may, therefore, also modulate hematopoiesis. HGF is secreted as a single inactive polypeptide which is cleaved by serine proteases into a 69kDa alpha chain and 34kDa beta chain. A disulfide bond linking the alpha and beta chains produces the active, heterodimeric molecule. Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 97278.10 |
Hepatocyte Growth Factor A Chain, human recombinant, His Tag (rHuHGFA) Bioassay HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity. (www.uniprot.org) Human recombinant HGF-A produced in E.coli is a single, non-glycosylated, polypeptide chain containing 463 amino acids fragment (32-494) having a molecular weight of 69kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. Hepatocyte Growth Factor (HGF) is a multifunctional growth factor which regulates both cell growth and cell motility. It exerts a strong mitogenic effect on hepatocytes and primary epithelial cells. HGF synergizes with Interleukin-3 and GM-CSF to stimulate colony formation of hematopoietic progenitor cells in vitro and may, therefore, also modulate hematopoiesis. HGF is secreted as a single inactive polypeptide which is cleaved by serine proteases into a 69kDa alpha chain and 34kDa beta chain. A disulfide bond linking the alpha and beta chains produces the active, heterodimeric molecule. Purity: >95% |
Biomol GmbH |
10 µg |
170 €
|
| 97278.2 |
Hepatocyte Growth Factor A Chain, human recombinant, His Tag (rHuHGFA) Bioassay HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity. (www.uniprot.org) Human recombinant HGF-A produced in E.coli is a single, non-glycosylated, polypeptide chain containing 463 amino acids fragment (32-494) having a molecular weight of 69kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. Hepatocyte Growth Factor (HGF) is a multifunctional growth factor which regulates both cell growth and cell motility. It exerts a strong mitogenic effect on hepatocytes and primary epithelial cells. HGF synergizes with Interleukin-3 and GM-CSF to stimulate colony formation of hematopoietic progenitor cells in vitro and may, therefore, also modulate hematopoiesis. HGF is secreted as a single inactive polypeptide which is cleaved by serine proteases into a 69kDa alpha chain and 34kDa beta chain. A disulfide bond linking the alpha and beta chains produces the active, heterodimeric molecule. Purity: >95% |
Biomol GmbH |
2 µg |
66 €
|
| 97279.1 |
Hepatocyte Growth Factor B Chain, human recombinant, His Tag (rHuHGFB) Bioassay HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity. (www.uniprot.org) Human recombinant HGF-B produced in E.coli is a single, non-glycosylated, polypeptide chain containing 234 amino acids fragment (495-728) having a molecular weight of 34kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. Hepatocyte Growth Factor (HGF) is a multifunctional growth factor which regulates both cell growth and cell motility. It exerts a strong mitogenic effect on hepatocytes and primary epithelial cells. HGF synergizes with Interleukin-3 and GM-CSF to stimulate colony formation of hematopoietic progenitor cells in vitro and may, therefore, also modulate hematopoiesis. HGF is secreted as a single inactive polypeptide which is cleaved by serine proteases into a 69kDa alpha chain and 34kDa beta chain. A disulfide bond linking the alpha and beta chains produces the active heterodimeric molecule. Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 97279.10 |
Hepatocyte Growth Factor B Chain, human recombinant, His Tag (rHuHGFB) Bioassay HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity. (www.uniprot.org) Human recombinant HGF-B produced in E.coli is a single, non-glycosylated, polypeptide chain containing 234 amino acids fragment (495-728) having a molecular weight of 34kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. Hepatocyte Growth Factor (HGF) is a multifunctional growth factor which regulates both cell growth and cell motility. It exerts a strong mitogenic effect on hepatocytes and primary epithelial cells. HGF synergizes with Interleukin-3 and GM-CSF to stimulate colony formation of hematopoietic progenitor cells in vitro and may, therefore, also modulate hematopoiesis. HGF is secreted as a single inactive polypeptide which is cleaved by serine proteases into a 69kDa alpha chain and 34kDa beta chain. A disulfide bond linking the alpha and beta chains produces the active heterodimeric molecule. Purity: >95% |
Biomol GmbH |
10 µg |
170 €
|
| 97279.2 |
Hepatocyte Growth Factor B Chain, human recombinant, His Tag (rHuHGFB) Bioassay HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be an hepatotrophic factor, and acts as growth factor for a broad spectrum of tissues and cell types. It has no detectable protease activity. (www.uniprot.org) Human recombinant HGF-B produced in E.coli is a single, non-glycosylated, polypeptide chain containing 234 amino acids fragment (495-728) having a molecular weight of 34kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. Hepatocyte Growth Factor (HGF) is a multifunctional growth factor which regulates both cell growth and cell motility. It exerts a strong mitogenic effect on hepatocytes and primary epithelial cells. HGF synergizes with Interleukin-3 and GM-CSF to stimulate colony formation of hematopoietic progenitor cells in vitro and may, therefore, also modulate hematopoiesis. HGF is secreted as a single inactive polypeptide which is cleaved by serine proteases into a 69kDa alpha chain and 34kDa beta chain. A disulfide bond linking the alpha and beta chains produces the active heterodimeric molecule. Purity: >95% |
Biomol GmbH |
2 µg |
66 €
|
| 97237.1 |
Osteopontin (Secreted Phosphoprotein-1), human recombinant Bioassay Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 321 amino acids (fragment 17-314). The SPP1 protein is fused to 20 amino acid His Tag at N-terminus. MW: 36.200 D Purity: >90% |
Biomol GmbH |
1 mg |
anfragen
|
| 97237.10 |
Osteopontin (Secreted Phosphoprotein-1), human recombinant Bioassay Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 321 amino acids (fragment 17-314). The SPP1 protein is fused to 20 amino acid His Tag at N-terminus. MW: 36.200 D Purity: >90% |
Biomol GmbH |
10 µg |
170 €
|
| 97237.2 |
Osteopontin (Secreted Phosphoprotein-1), human recombinant Bioassay Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 321 amino acids (fragment 17-314). The SPP1 protein is fused to 20 amino acid His Tag at N-terminus. MW: 36.200 D Purity: >90% |
Biomol GmbH |
2 µg |
66 €
|
| 94971.1 |
Tumor Necrosis Factor Receptor Fusion Protein, human recombinant (rHuTNFR) Cell culture Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. (www.uniprot.org) Produced in CHO as a dimeric, glycosylated, polypeptide chain consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 94971.10 |
Tumor Necrosis Factor Receptor Fusion Protein, human recombinant (rHuTNFR) Cell culture Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. (www.uniprot.org) Produced in CHO as a dimeric, glycosylated, polypeptide chain consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. |
Biomol GmbH |
10 µg |
66 €
|
| 94971.50 |
Tumor Necrosis Factor Receptor Fusion Protein, human recombinant (rHuTNFR) Cell culture Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. (www.uniprot.org) Produced in CHO as a dimeric, glycosylated, polypeptide chain consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. |
Biomol GmbH |
50 µg |
170 €
|
| 97288.1 |
Tumor Necrosis Factor Receptor Type 2, human recombinant, His Tag (rHuTNFR2) Bioassay Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. (www.uniprot.org) Human recombinant TNFR2 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 184 amino acids fragment (23-206) having a molecular weight of 25kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. TNFR2 belongs to the TNF-receptor superfamily. TNFR2 is receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. TNFR2 mediates the majority of the metabolic effects of TNF-alpha. In addition, knockout studies in mice propose a role for TNFR2 in protecting neurons from apoptosis by stimulating antioxidative pathways. TNFR2 expression might have a significant role in the angiogenesis, tumor cell proliferation and metastasis of Invasive micropapillary carcinoma of the breast. Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 97288.20 |
Tumor Necrosis Factor Receptor Type 2, human recombinant, His Tag (rHuTNFR2) Bioassay Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. (www.uniprot.org) Human recombinant TNFR2 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 184 amino acids fragment (23-206) having a molecular weight of 25kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. TNFR2 belongs to the TNF-receptor superfamily. TNFR2 is receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. TNFR2 mediates the majority of the metabolic effects of TNF-alpha. In addition, knockout studies in mice propose a role for TNFR2 in protecting neurons from apoptosis by stimulating antioxidative pathways. TNFR2 expression might have a significant role in the angiogenesis, tumor cell proliferation and metastasis of Invasive micropapillary carcinoma of the breast. Purity: >95% |
Biomol GmbH |
20 µg |
170 €
|
| 97288.5 |
Tumor Necrosis Factor Receptor Type 2, human recombinant, His Tag (rHuTNFR2) Bioassay Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. (www.uniprot.org) Human recombinant TNFR2 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 184 amino acids fragment (23-206) having a molecular weight of 25kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. TNFR2 belongs to the TNF-receptor superfamily. TNFR2 is receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. TNFR2 mediates the majority of the metabolic effects of TNF-alpha. In addition, knockout studies in mice propose a role for TNFR2 in protecting neurons from apoptosis by stimulating antioxidative pathways. TNFR2 expression might have a significant role in the angiogenesis, tumor cell proliferation and metastasis of Invasive micropapillary carcinoma of the breast. Purity: >95% |
Biomol GmbH |
5 µg |
66 €
|
|
97312.1 |
Allograft Inflammatory Factor, human recombinant, FLAG Tag (rHuAIF-1) WB Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. (www.uniprot.org) Human recombinant AIF1 contains a total of 155 amino acids having a molecular Mass of 17.7kDa. The Human AIF1 is fused to a 9 amino acid long N-terminal FLAG tag. Human AIF1 protein shares 98% homology/identity with that of rat. AIF1 is expressed in macrophages and neutrophils. The expression of AIF1 transcripts is upregulated by IFN-g in rat macrophages. AIF1 is expressed selectively in human macrophage-like cell lines, and in a subset of CD68() macrophages in the interstitial and perivascular spaces of human heart allografts. In quiescent cultured human vascular smooth muscle cells synthesis of AIF1 is induced by IFN-g, IL1b, and conditioned medium of T-cells. Overexpression of AIF1 in human VSMCs results in enhanced growth of these cells. AIF1 is expressed during apoptosis rat mammary gland and ventral prostate tissues. Allograft Inflammatory Factor 1 is expressed by several tumor-associated activated macrophages and microglial cells in rat and human gliomas. There is an evident relationship of AIF1-expressing activated macrophages and microglial cells with tumor maligna MW: 17.700 D Purity: >90% |
Biomol GmbH |
1 mg |
eingest.
|
|
97312.10 |
Allograft Inflammatory Factor, human recombinant, FLAG Tag (rHuAIF-1) WB Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. (www.uniprot.org) Human recombinant AIF1 contains a total of 155 amino acids having a molecular Mass of 17.7kDa. The Human AIF1 is fused to a 9 amino acid long N-terminal FLAG tag. Human AIF1 protein shares 98% homology/identity with that of rat. AIF1 is expressed in macrophages and neutrophils. The expression of AIF1 transcripts is upregulated by IFN-g in rat macrophages. AIF1 is expressed selectively in human macrophage-like cell lines, and in a subset of CD68() macrophages in the interstitial and perivascular spaces of human heart allografts. In quiescent cultured human vascular smooth muscle cells synthesis of AIF1 is induced by IFN-g, IL1b, and conditioned medium of T-cells. Overexpression of AIF1 in human VSMCs results in enhanced growth of these cells. AIF1 is expressed during apoptosis rat mammary gland and ventral prostate tissues. Allograft Inflammatory Factor 1 is expressed by several tumor-associated activated macrophages and microglial cells in rat and human gliomas. There is an evident relationship of AIF1-expressing activated macrophages and microglial cells with tumor maligna MW: 17.700 D Purity: >90% |
Biomol GmbH |
10 µg |
eingest.
|
|
97312.2 |
Allograft Inflammatory Factor, human recombinant, FLAG Tag (rHuAIF-1) WB Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. (www.uniprot.org) Human recombinant AIF1 contains a total of 155 amino acids having a molecular Mass of 17.7kDa. The Human AIF1 is fused to a 9 amino acid long N-terminal FLAG tag. Human AIF1 protein shares 98% homology/identity with that of rat. AIF1 is expressed in macrophages and neutrophils. The expression of AIF1 transcripts is upregulated by IFN-g in rat macrophages. AIF1 is expressed selectively in human macrophage-like cell lines, and in a subset of CD68() macrophages in the interstitial and perivascular spaces of human heart allografts. In quiescent cultured human vascular smooth muscle cells synthesis of AIF1 is induced by IFN-g, IL1b, and conditioned medium of T-cells. Overexpression of AIF1 in human VSMCs results in enhanced growth of these cells. AIF1 is expressed during apoptosis rat mammary gland and ventral prostate tissues. Allograft Inflammatory Factor 1 is expressed by several tumor-associated activated macrophages and microglial cells in rat and human gliomas. There is an evident relationship of AIF1-expressing activated macrophages and microglial cells with tumor maligna MW: 17.700 D Purity: >90% |
Biomol GmbH |
2 µg |
eingest.
|
|
97375.1 |
Allograft Inflammatory Factor, His Tag, human recombinant, (rHuAIF-1-His) WB Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. (www.uniprot.org) Human recombinant AIF1 contains a total of 155 amino acids having a molecular Mass of 17.7kDa. The Human AIF1 is fused to a 9 amino acid long N-terminal His tag. Human AIF1 protein shares 98% homology/identity with that of rat. AIF1 is expressed in macrophages and neutrophils. The expression of AIF1 transcripts is upregulated by IFN-g in rat macrophages. AIF1 is expressed selectively in human macrophage-like cell lines, and in a subset of CD68() macrophages in the interstitial and perivascular spaces of human heart allografts. In quiescent cultured human vascular smooth muscle cells synthesis of AIF1 is induced by IFN-g, IL1b, and conditioned medium of T-cells. Overexpression of AIF1 in human VSMCs results in enhanced growth of these cells. AIF1 is expressed during apoptosis rat mammary gland and ventral prostate tissues. Allograft Inflammatory Factor 1 is expressed by several tumor-associated activated macrophages and microglial cells in rat and human gliomas. There is an evident relationship of AIF1-expressing activated macrophages and microglial cells with tumor malignan MW: 17.700 D Purity: >90% |
Biomol GmbH |
1 mg |
anfragen
|
|
97375.10 |
Allograft Inflammatory Factor, His Tag, human recombinant, (rHuAIF-1-His) WB Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. (www.uniprot.org) Human recombinant AIF1 contains a total of 155 amino acids having a molecular Mass of 17.7kDa. The Human AIF1 is fused to a 9 amino acid long N-terminal His tag. Human AIF1 protein shares 98% homology/identity with that of rat. AIF1 is expressed in macrophages and neutrophils. The expression of AIF1 transcripts is upregulated by IFN-g in rat macrophages. AIF1 is expressed selectively in human macrophage-like cell lines, and in a subset of CD68() macrophages in the interstitial and perivascular spaces of human heart allografts. In quiescent cultured human vascular smooth muscle cells synthesis of AIF1 is induced by IFN-g, IL1b, and conditioned medium of T-cells. Overexpression of AIF1 in human VSMCs results in enhanced growth of these cells. AIF1 is expressed during apoptosis rat mammary gland and ventral prostate tissues. Allograft Inflammatory Factor 1 is expressed by several tumor-associated activated macrophages and microglial cells in rat and human gliomas. There is an evident relationship of AIF1-expressing activated macrophages and microglial cells with tumor malignan MW: 17.700 D Purity: >90% |
Biomol GmbH |
10 µg |
175 €
|
|
97375.2 |
Allograft Inflammatory Factor, His Tag, human recombinant, (rHuAIF-1-His) WB Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. (www.uniprot.org) Human recombinant AIF1 contains a total of 155 amino acids having a molecular Mass of 17.7kDa. The Human AIF1 is fused to a 9 amino acid long N-terminal His tag. Human AIF1 protein shares 98% homology/identity with that of rat. AIF1 is expressed in macrophages and neutrophils. The expression of AIF1 transcripts is upregulated by IFN-g in rat macrophages. AIF1 is expressed selectively in human macrophage-like cell lines, and in a subset of CD68() macrophages in the interstitial and perivascular spaces of human heart allografts. In quiescent cultured human vascular smooth muscle cells synthesis of AIF1 is induced by IFN-g, IL1b, and conditioned medium of T-cells. Overexpression of AIF1 in human VSMCs results in enhanced growth of these cells. AIF1 is expressed during apoptosis rat mammary gland and ventral prostate tissues. Allograft Inflammatory Factor 1 is expressed by several tumor-associated activated macrophages and microglial cells in rat and human gliomas. There is an evident relationship of AIF1-expressing activated macrophages and microglial cells with tumor malignan MW: 17.700 D Purity: >90% |
Biomol GmbH |
2 µg |
68 €
|
| 50442.1 |
Interleukin-2, human recombinant (rHuIL-2) Cell culture Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated mutein (variant form) of human IL-2 polypeptide chain containing 134 amino acids. The ED50 as determined by the dose-dependant stimulation of murine CTLL-2 cells is < 0.0645 ng/ml. MW: 15.520 D Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 50442.10 |
Interleukin-2, human recombinant (rHuIL-2) Cell culture Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated mutein (variant form) of human IL-2 polypeptide chain containing 134 amino acids. The ED50 as determined by the dose-dependant stimulation of murine CTLL-2 cells is < 0.0645 ng/ml. MW: 15.520 D |
Biomol GmbH |
10 µg |
66 €
|
| 50442.50 |
Interleukin-2, human recombinant (rHuIL-2) Cell culture Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated mutein (variant form) of human IL-2 polypeptide chain containing 134 amino acids. The ED50 as determined by the dose-dependant stimulation of murine CTLL-2 cells is < 0.0645 ng/ml. MW: 15.520 D |
Biomol GmbH |
50 µg |
170 €
|
| 97280.1 |
Interleukin-2, human recombinant, His Tag (rHuIL-2) Bioassay Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. (www.uniprot.org) Human recombinant Interleukin-2 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 133 amino acids fragment (21-153) having a molecular weight of 21kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. IL-2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin-4 (IL4) and interleukin-7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 97280.10 |
Interleukin-2, human recombinant, His Tag (rHuIL-2) Bioassay Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. (www.uniprot.org) Human recombinant Interleukin-2 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 133 amino acids fragment (21-153) having a molecular weight of 21kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. IL-2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin-4 (IL4) and interleukin-7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. Purity: >95% |
Biomol GmbH |
10 µg |
170 €
|
| 97280.2 |
Interleukin-2, human recombinant, His Tag (rHuIL-2) Bioassay Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. (www.uniprot.org) Human recombinant Interleukin-2 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 133 amino acids fragment (21-153) having a molecular weight of 21kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. IL-2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin-4 (IL4) and interleukin-7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. Purity: >95% |
Biomol GmbH |
2 µg |
66 €
|
| 99902.100 |
Interleukin-2 (IL-2), human recombinant, plant based, bio-clean (rHuIL-2) Cell culture Active protein produced in the endosperm tissue of barley grain. This production system uses barley endosperm storage cell which is characterised by its biochemically inert environment and lack of endotoxins. The barley endosperm tissue has a very low protease activity in comparison to most other cellular organisms, resulting in the unique protein storage function of the seed, that can maintain the proteins, including recombinant proteins, intact for years. The recombinant product is Aminal and Serum-free and therefore void of any human or animal viral contaminants that could jeopardize your cell culture. The purified recombinant protein carries no pyrogenic or pro-inflammatory contaminants. The Endotoxin level is less than 0.005ng per µg of recombinant protein (0.05EU/µg). Recombinant human IL-2 contains 133 amino acids and a 16 a.a. histidine-based tag for a total length of 149 a.a. and has a predicted molecular mass of 17.5 kDa. The recombinant protein migrates with an apparent molecular mass of 22 kDa in SDS-PAGE. |
Biomol GmbH |
100 µg |
199 €
|
| 99902.1000 |
Interleukin-2 (IL-2), human recombinant, plant based, bio-clean (rHuIL-2) Cell culture Active protein produced in the endosperm tissue of barley grain. This production system uses barley endosperm storage cell which is characterised by its biochemically inert environment and lack of endotoxins. The barley endosperm tissue has a very low protease activity in comparison to most other cellular organisms, resulting in the unique protein storage function of the seed, that can maintain the proteins, including recombinant proteins, intact for years. The recombinant product is Aminal and Serum-free and therefore void of any human or animal viral contaminants that could jeopardize your cell culture. The purified recombinant protein carries no pyrogenic or pro-inflammatory contaminants. The Endotoxin level is less than 0.005ng per µg of recombinant protein (0.05EU/µg). Recombinant human IL-2 contains 133 amino acids and a 16 a.a. histidine-based tag for a total length of 149 a.a. and has a predicted molecular mass of 17.5 kDa. The recombinant protein migrates with an apparent molecular mass of 22 kDa in SDS-PAGE. |
Biomol GmbH |
1000 µg |
679 €
|
| 99902.50 |
Interleukin-2 (IL-2), human recombinant, plant based, bio-clean (rHuIL-2) Cell culture Active protein produced in the endosperm tissue of barley grain. This production system uses barley endosperm storage cell which is characterised by its biochemically inert environment and lack of endotoxins. The barley endosperm tissue has a very low protease activity in comparison to most other cellular organisms, resulting in the unique protein storage function of the seed, that can maintain the proteins, including recombinant proteins, intact for years. The recombinant product is Aminal and Serum-free and therefore void of any human or animal viral contaminants that could jeopardize your cell culture. The purified recombinant protein carries no pyrogenic or pro-inflammatory contaminants. The Endotoxin level is less than 0.005ng per µg of recombinant protein (0.05EU/µg). Recombinant human IL-2 contains 133 amino acids and a 16 a.a. histidine-based tag for a total length of 149 a.a. and has a predicted molecular mass of 17.5 kDa. The recombinant protein migrates with an apparent molecular mass of 22 kDa in SDS-PAGE. |
Biomol GmbH |
50 µg |
165 €
|
| 97113.1 |
Interleukin-27, mouse recombinant (rmIL-27) Cell culture Cytokine with pro- and anti-inflammatory properties, that can regulate T helper cell development, suppress T-cell proliferation, stimulate cytotoxic T cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR which appears to be required but not sufficient for IL-27-mediated signal transduction. IL-27 potentiate the early phase of TH1 response and suppress TH2 and TH17 differentiation. It induces the differentiation of TH1 cells via two distinct pathways, p38 MAPK/TBX21- and ICAM1/ITGAL/ERK-dependent pathways. It also induces STAT1, STAT3, STAT4 and STAT5 phosphorylation and activates TBX21/T-Bet via STAT1 with resulting IL12RB2 up-regulation, an event crucial to TH1 cell commitment. It suppresses the expression of GATA3, the inhibitor TH1 cells development. In CD8 T-cells, it activates STATs as well as GZMB. IL-27 reveals to be a potent inhibitor of TH17 cell development and of IL-17 production. Indeed IL-27 subunit p28 alone is also able to inhibit the production of IL17 by CD4 and CD8 T-cells. While IL-27 suppressed the development of proin Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 97113.10 |
Interleukin-27, mouse recombinant (rmIL-27) Cell culture Cytokine with pro- and anti-inflammatory properties, that can regulate T helper cell development, suppress T-cell proliferation, stimulate cytotoxic T cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR which appears to be required but not sufficient for IL-27-mediated signal transduction. IL-27 potentiate the early phase of TH1 response and suppress TH2 and TH17 differentiation. It induces the differentiation of TH1 cells via two distinct pathways, p38 MAPK/TBX21- and ICAM1/ITGAL/ERK-dependent pathways. It also induces STAT1, STAT3, STAT4 and STAT5 phosphorylation and activates TBX21/T-Bet via STAT1 with resulting IL12RB2 up-regulation, an event crucial to TH1 cell commitment. It suppresses the expression of GATA3, the inhibitor TH1 cells development. In CD8 T-cells, it activates STATs as well as GZMB. IL-27 reveals to be a potent inhibitor of TH17 cell development and of IL-17 production. Indeed IL-27 subunit p28 alone is also able to inhibit the production of IL17 by CD4 and CD8 T-cells. While IL-27 suppressed the development of proin |
Biomol GmbH |
10 µg |
170 €
|
| 97113.2 |
Interleukin-27, mouse recombinant (rmIL-27) Cell culture Cytokine with pro- and anti-inflammatory properties, that can regulate T helper cell development, suppress T-cell proliferation, stimulate cytotoxic T cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR which appears to be required but not sufficient for IL-27-mediated signal transduction. IL-27 potentiate the early phase of TH1 response and suppress TH2 and TH17 differentiation. It induces the differentiation of TH1 cells via two distinct pathways, p38 MAPK/TBX21- and ICAM1/ITGAL/ERK-dependent pathways. It also induces STAT1, STAT3, STAT4 and STAT5 phosphorylation and activates TBX21/T-Bet via STAT1 with resulting IL12RB2 up-regulation, an event crucial to TH1 cell commitment. It suppresses the expression of GATA3, the inhibitor TH1 cells development. In CD8 T-cells, it activates STATs as well as GZMB. IL-27 reveals to be a potent inhibitor of TH17 cell development and of IL-17 production. Indeed IL-27 subunit p28 alone is also able to inhibit the production of IL17 by CD4 and CD8 T-cells. While IL-27 suppressed the development of proin |
Biomol GmbH |
2 µg |
66 €
|
| 08535.1 |
Trefoil Factor-1 (TFF1), human recombinant (rHuTFF1) Cell culture Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine. (www.uniprot.org) Produced in E.coli as a homodimer, non-glycosylated, polypeptide chain containing 2 x 60 amino acids which includes a 40 amino acid trefoil motif containing 3 conserved interamolecular disulfide bonds. MW: 13.200 D Purity: >97% |
Biomol GmbH |
1 mg |
anfragen
|
| 08535.20 |
Trefoil Factor-1 (TFF1), human recombinant (rHuTFF1) Cell culture Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine. (www.uniprot.org) Produced in E.coli as a homodimer, non-glycosylated, polypeptide chain containing 2 x 60 amino acids which includes a 40 amino acid trefoil motif containing 3 conserved interamolecular disulfide bonds. MW: 13.200 D |
Biomol GmbH |
20 µg |
170 €
|
| 08535.5 |
Trefoil Factor-1 (TFF1), human recombinant (rHuTFF1) Cell culture Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine. (www.uniprot.org) Produced in E.coli as a homodimer, non-glycosylated, polypeptide chain containing 2 x 60 amino acids which includes a 40 amino acid trefoil motif containing 3 conserved interamolecular disulfide bonds. MW: 13.200 D |
Biomol GmbH |
5 µg |
66 €
|
| 08559.1 |
Trefoil Factor-1 (TFF1), human recombinant, His Tag (rHuTFF1) Cell biology studies Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 70 amino acids (25-84) which includes a 10 amino acid His Tag. MW: 7.900 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 08559.20 |
Trefoil Factor-1 (TFF1), human recombinant, His Tag (rHuTFF1) Cell biology studies Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 70 amino acids (25-84) which includes a 10 amino acid His Tag. MW: 7.900 D |
Biomol GmbH |
20 µg |
170 €
|
| 08559.5 |
Trefoil Factor-1 (TFF1), human recombinant, His Tag (rHuTFF1) Cell biology studies Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 70 amino acids (25-84) which includes a 10 amino acid His Tag. MW: 7.900 D |
Biomol GmbH |
5 µg |
66 €
|
| 87410.1 |
Insulin-Like Growth Factor Binding Protein-1, human recombinant (rHuIGFBP-1) Cell Culture IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. (www.uniprot.org) Produced in NSO cells. Single glycosylated polypeptide chain, 218 amino acids. Inhib. of IGF-I stimulated prolif. of NUC-1 cells: IC50 ~100 ng/ml. Inhib. of serum-induced stimulation of DNA synthesis in chick embryo fibroblast: IC50 ~300 ng/ml. MW: 28.806 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 87410.10 |
Insulin-Like Growth Factor Binding Protein-1, human recombinant (rHuIGFBP-1) Cell Culture IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. (www.uniprot.org) Produced in NSO cells. Single glycosylated polypeptide chain, 218 amino acids. Inhib. of IGF-I stimulated prolif. of NUC-1 cells: IC50 ~100 ng/ml. Inhib. of serum-induced stimulation of DNA synthesis in chick embryo fibroblast: IC50 ~300 ng/ml. MW: 28.806 D |
Biomol GmbH |
10 µg |
849 €
|
| 87410.2 |
Insulin-Like Growth Factor Binding Protein-1, human recombinant (rHuIGFBP-1) Cell Culture IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. (www.uniprot.org) Produced in NSO cells. Single glycosylated polypeptide chain, 218 amino acids. Inhib. of IGF-I stimulated prolif. of NUC-1 cells: IC50 ~100 ng/ml. Inhib. of serum-induced stimulation of DNA synthesis in chick embryo fibroblast: IC50 ~300 ng/ml. MW: 28.806 D |
Biomol GmbH |
2 µg |
264 €
|
| 94894.1 |
CD40 Ligand/TRAP, soluble, human recombinant (rHusCD40L/TRAP) Cell culture Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. (www.uniprot.org) Produced in E.coli as a non-glycosylated, polypeptide chain containing 149 amino acids. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. MW: 16.308 D Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 94894.10 |
CD40 Ligand/TRAP, soluble, human recombinant (rHusCD40L/TRAP) Cell culture Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. (www.uniprot.org) Produced in E.coli as a non-glycosylated, polypeptide chain containing 149 amino acids. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. MW: 16.308 D |
Biomol GmbH |
10 µg |
66 €
|
| 94894.50 |
CD40 Ligand/TRAP, soluble, human recombinant (rHusCD40L/TRAP) Cell culture Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. (www.uniprot.org) Produced in E.coli as a non-glycosylated, polypeptide chain containing 149 amino acids. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. MW: 16.308 D |
Biomol GmbH |
50 µg |
170 €
|
| 97284.1 |
Soluble CD40 Ligand, human recombinant, His Tag (rHuTRAP) Bioassay Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. (www.uniprot.org) Human recombinant sCD40 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 149 amino acids fragment (113-261) corresponding to the receptor binding domain of the sCD40L protein, having a molecular weight of 21.5kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. CD40L or CD154 is a membrane glycoprotein and differentiation antigen expressed on the surface of T-cells. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also costimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL-2. Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 97284.20 |
Soluble CD40 Ligand, human recombinant, His Tag (rHuTRAP) Bioassay Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. (www.uniprot.org) Human recombinant sCD40 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 149 amino acids fragment (113-261) corresponding to the receptor binding domain of the sCD40L protein, having a molecular weight of 21.5kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. CD40L or CD154 is a membrane glycoprotein and differentiation antigen expressed on the surface of T-cells. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also costimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL-2. Purity: >95% |
Biomol GmbH |
20 µg |
170 €
|
| 97284.5 |
Soluble CD40 Ligand, human recombinant, His Tag (rHuTRAP) Bioassay Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. (www.uniprot.org) Human recombinant sCD40 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 149 amino acids fragment (113-261) corresponding to the receptor binding domain of the sCD40L protein, having a molecular weight of 21.5kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. CD40L or CD154 is a membrane glycoprotein and differentiation antigen expressed on the surface of T-cells. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also costimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL-2. Purity: >95% |
Biomol GmbH |
5 µg |
66 €
|
| 87316.1 |
Growth and Differentiation Factor-5, human recombinant (rHuGDF-5) Cell Culture Could be involved in bone and cartilage formation. Chondrogenic signaling is mediated by the high-affinity receptor BMPR1B. (www.uniprot.org) Produced in E.coli. Homodimer, non-glycosylated, polypeptide chain containing 2 x 117 amino acids. To enable bacterial expression of rhGDF-5 we removed the N-terminal sequence Ala-Pro-Leu-Thr and added the Lys. MW: 26.800 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 87316.10 |
Growth and Differentiation Factor-5, human recombinant (rHuGDF-5) Cell Culture Could be involved in bone and cartilage formation. Chondrogenic signaling is mediated by the high-affinity receptor BMPR1B. (www.uniprot.org) Produced in E.coli. Homodimer, non-glycosylated, polypeptide chain containing 2 x 117 amino acids. To enable bacterial expression of rhGDF-5 we removed the N-terminal sequence Ala-Pro-Leu-Thr and added the Lys. MW: 26.800 D |
Biomol GmbH |
10 µg |
66 €
|
| 87316.50 |
Growth and Differentiation Factor-5, human recombinant (rHuGDF-5) Cell Culture Could be involved in bone and cartilage formation. Chondrogenic signaling is mediated by the high-affinity receptor BMPR1B. (www.uniprot.org) Produced in E.coli. Homodimer, non-glycosylated, polypeptide chain containing 2 x 117 amino acids. To enable bacterial expression of rhGDF-5 we removed the N-terminal sequence Ala-Pro-Leu-Thr and added the Lys. MW: 26.800 D |
Biomol GmbH |
50 µg |
170 €
|
| 97267.1 |
Growth Differentiation Factor 5, human recombinant, His Tag (rHuGDF5) Bioassay Could be involved in bone and cartilage formation. Chondrogenic signaling is mediated by the high-affinity receptor BMPR1B. (www.uniprot.org) Human recombinant GDF5 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 141 amino acids (fragment 382-501) and having a total molecular mass of 15.8 kDa. GDF5 is fused to 20 amino acid His Tag at N-terminus. GDF-5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia (Hunter-Thompson type), brachydactyly (type C) and chondrodysplasia (Grebe type). These associations confirm that the gene product plays a role in skeletal development. MW: 15.800 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 97267.25 |
Growth Differentiation Factor 5, human recombinant, His Tag (rHuGDF5) Bioassay Could be involved in bone and cartilage formation. Chondrogenic signaling is mediated by the high-affinity receptor BMPR1B. (www.uniprot.org) Human recombinant GDF5 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 141 amino acids (fragment 382-501) and having a total molecular mass of 15.8 kDa. GDF5 is fused to 20 amino acid His Tag at N-terminus. GDF-5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia (Hunter-Thompson type), brachydactyly (type C) and chondrodysplasia (Grebe type). These associations confirm that the gene product plays a role in skeletal development. MW: 15.800 D Purity: >95% |
Biomol GmbH |
25 µg |
170 €
|
| 97267.5 |
Growth Differentiation Factor 5, human recombinant, His Tag (rHuGDF5) Bioassay Could be involved in bone and cartilage formation. Chondrogenic signaling is mediated by the high-affinity receptor BMPR1B. (www.uniprot.org) Human recombinant GDF5 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 141 amino acids (fragment 382-501) and having a total molecular mass of 15.8 kDa. GDF5 is fused to 20 amino acid His Tag at N-terminus. GDF-5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia (Hunter-Thompson type), brachydactyly (type C) and chondrodysplasia (Grebe type). These associations confirm that the gene product plays a role in skeletal development. MW: 15.800 D Purity: >95% |
Biomol GmbH |
5 µg |
66 €
|
| 94974.1 |
Interleukin-33, human recombinant (rHuIL-33) Cell biology studies Cytokine that binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Induces T helper type 2-associated cytokines. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 160 amino acids. MW: 18.000 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 94974.10 |
Interleukin-33, human recombinant (rHuIL-33) Cell biology studies Cytokine that binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Induces T helper type 2-associated cytokines. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 160 amino acids. MW: 18.000 D |
Biomol GmbH |
10 µg |
170 €
|
| 94974.2 |
Interleukin-33, human recombinant (rHuIL-33) Cell biology studies Cytokine that binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Induces T helper type 2-associated cytokines. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 160 amino acids. MW: 18.000 D |
Biomol GmbH |
2 µg |
66 €
|
| 97281.1 |
Interleukin-33, human recombinant, His Tag (rHuIL-33) Bioassay Cytokine that binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Induces T helper type 2-associated cytokines. (www.uniprot.org) Human recombinant Interleukin-33 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 159 amino acids C-terminal fragment (112-270) having a molecular weight of 20.5kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. Interleukin-33 (IL-33) is a 32kDa proinflammatory cytokine that may also regulate gene transcription in producer cells. IL-33 is structurally related to IL-1, which induces helper T-cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1), which is known also as ST2. Binding of IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces expression of IL-4, IL-5, IL-13 and leads to severe pathological changes in mucosal organs and in vitro, it can be divided to N-terminal fragment of 12kDa and C-terminal fragment of 18kDa by cleavage of caspase-1. Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 97281.10 |
Interleukin-33, human recombinant, His Tag (rHuIL-33) Bioassay Cytokine that binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Induces T helper type 2-associated cytokines. (www.uniprot.org) Human recombinant Interleukin-33 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 159 amino acids C-terminal fragment (112-270) having a molecular weight of 20.5kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. Interleukin-33 (IL-33) is a 32kDa proinflammatory cytokine that may also regulate gene transcription in producer cells. IL-33 is structurally related to IL-1, which induces helper T-cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1), which is known also as ST2. Binding of IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces expression of IL-4, IL-5, IL-13 and leads to severe pathological changes in mucosal organs and in vitro, it can be divided to N-terminal fragment of 12kDa and C-terminal fragment of 18kDa by cleavage of caspase-1. Purity: >95% |
Biomol GmbH |
10 µg |
170 €
|
| 97281.2 |
Interleukin-33, human recombinant, His Tag (rHuIL-33) Bioassay Cytokine that binds to and signals through IL1RL1/ST2 and its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Induces T helper type 2-associated cytokines. (www.uniprot.org) Human recombinant Interleukin-33 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 159 amino acids C-terminal fragment (112-270) having a molecular weight of 20.5kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. Interleukin-33 (IL-33) is a 32kDa proinflammatory cytokine that may also regulate gene transcription in producer cells. IL-33 is structurally related to IL-1, which induces helper T-cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1), which is known also as ST2. Binding of IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces expression of IL-4, IL-5, IL-13 and leads to severe pathological changes in mucosal organs and in vitro, it can be divided to N-terminal fragment of 12kDa and C-terminal fragment of 18kDa by cleavage of caspase-1. Purity: >95% |
Biomol GmbH |
2 µg |
66 €
|
| 69741.1 |
Apolipoprotein D, His Tag, human recombinant (rHuApo-D-His) Cell culture APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 174 amino acids and having a C-terminal His Tag Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 69741.10 |
Apolipoprotein D, His Tag, human recombinant (rHuApo-D-His) Cell culture APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 174 amino acids and having a C-terminal His Tag |
Biomol GmbH |
10 µg |
170 €
|
| 69741.2 |
Apolipoprotein D, His Tag, human recombinant (rHuApo-D-His) Cell culture APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 174 amino acids and having a C-terminal His Tag |
Biomol GmbH |
2 µg |
66 €
|
| 97266.1 |
Apolipoprotein D, human recombinant, GST Tag (rHuAPO-D) ELISA, WB, Inhibition assays APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts. (www.uniprot.org) Human recombinant APO-D full length protein expressed in E.coli shows a 48 kDa band on SDS-PAGE.The Apolipoprotein-D is mainly associated with high density lipoproteins in human plasma. Apolipoprotein-D is an atypical apolipoprotein and, based on its primary structure, Apolipoprotein-D is a member of the lipocalin family. Lipocalins adopt a beta-barrel tertiary structure and transport small hydrophobic ligands. Apolipoprotein-D binds cholesterol, progesterone, pregnenolone, bilirubin and arachidonic acid. Apolipoprotein-D is expressed in numerous tissues having high levels of expression in spleen, testes and brain. Apolipoprotein-D is present at high concentrations in the cyst fluid of women with gross cystic disease of the breast, a condition associated with increased risk of breast cancer. Apolipoprotein-D accumulates in regenerating peripheral nerves and in the cerebrospinal fluid of patients with neurodegenerative conditions, such as Alzheimer's disease. Apolipoprotein-D participates in maintenance and repair within the central and peripheral nervous systems. Apolipoprotein-D is a multi-ligand, multi-functional transporter and transports a ligand from 1 cell to another within an organ, scavenge a ligand within an organ for MW: 48.000 D |
Biomol GmbH |
1 mg |
anfragen
|
| 97266.10 |
Apolipoprotein D, human recombinant, GST Tag (rHuAPO-D) ELISA, WB, Inhibition assays APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts. (www.uniprot.org) Human recombinant APO-D full length protein expressed in E.coli shows a 48 kDa band on SDS-PAGE.The Apolipoprotein-D is mainly associated with high density lipoproteins in human plasma. Apolipoprotein-D is an atypical apolipoprotein and, based on its primary structure, Apolipoprotein-D is a member of the lipocalin family. Lipocalins adopt a beta-barrel tertiary structure and transport small hydrophobic ligands. Apolipoprotein-D binds cholesterol, progesterone, pregnenolone, bilirubin and arachidonic acid. Apolipoprotein-D is expressed in numerous tissues having high levels of expression in spleen, testes and brain. Apolipoprotein-D is present at high concentrations in the cyst fluid of women with gross cystic disease of the breast, a condition associated with increased risk of breast cancer. Apolipoprotein-D accumulates in regenerating peripheral nerves and in the cerebrospinal fluid of patients with neurodegenerative conditions, such as Alzheimer's disease. Apolipoprotein-D participates in maintenance and repair within the central and peripheral nervous systems. Apolipoprotein-D is a multi-ligand, multi-functional transporter and transports a ligand from 1 cell to another within an organ, scavenge a ligand within an organ for MW: 48.000 D |
Biomol GmbH |
10 µg |
735 €
|
| 97266.2 |
Apolipoprotein D, human recombinant, GST Tag (rHuAPO-D) ELISA, WB, Inhibition assays APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts. (www.uniprot.org) Human recombinant APO-D full length protein expressed in E.coli shows a 48 kDa band on SDS-PAGE.The Apolipoprotein-D is mainly associated with high density lipoproteins in human plasma. Apolipoprotein-D is an atypical apolipoprotein and, based on its primary structure, Apolipoprotein-D is a member of the lipocalin family. Lipocalins adopt a beta-barrel tertiary structure and transport small hydrophobic ligands. Apolipoprotein-D binds cholesterol, progesterone, pregnenolone, bilirubin and arachidonic acid. Apolipoprotein-D is expressed in numerous tissues having high levels of expression in spleen, testes and brain. Apolipoprotein-D is present at high concentrations in the cyst fluid of women with gross cystic disease of the breast, a condition associated with increased risk of breast cancer. Apolipoprotein-D accumulates in regenerating peripheral nerves and in the cerebrospinal fluid of patients with neurodegenerative conditions, such as Alzheimer's disease. Apolipoprotein-D participates in maintenance and repair within the central and peripheral nervous systems. Apolipoprotein-D is a multi-ligand, multi-functional transporter and transports a ligand from 1 cell to another within an organ, scavenge a ligand within an organ for MW: 48.000 D |
Biomol GmbH |
2 µg |
264 €
|
| 97266.5 |
Apolipoprotein D, human recombinant, GST Tag (rHuAPO-D) ELISA, WB, Inhibition assays APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts. (www.uniprot.org) Human recombinant APO-D full length protein expressed in E.coli shows a 48 kDa band on SDS-PAGE.The Apolipoprotein-D is mainly associated with high density lipoproteins in human plasma. Apolipoprotein-D is an atypical apolipoprotein and, based on its primary structure, Apolipoprotein-D is a member of the lipocalin family. Lipocalins adopt a beta-barrel tertiary structure and transport small hydrophobic ligands. Apolipoprotein-D binds cholesterol, progesterone, pregnenolone, bilirubin and arachidonic acid. Apolipoprotein-D is expressed in numerous tissues having high levels of expression in spleen, testes and brain. Apolipoprotein-D is present at high concentrations in the cyst fluid of women with gross cystic disease of the breast, a condition associated with increased risk of breast cancer. Apolipoprotein-D accumulates in regenerating peripheral nerves and in the cerebrospinal fluid of patients with neurodegenerative conditions, such as Alzheimer's disease. Apolipoprotein-D participates in maintenance and repair within the central and peripheral nervous systems. Apolipoprotein-D is a multi-ligand, multi-functional transporter and transports a ligand from 1 cell to another within an organ, scavenge a ligand within an organ for MW: 48.000 D |
Biomol GmbH |
5 µg |
399 €
|
| 94966.1 |
Neuregulin-1 beta2 / Heregulin-b2, human recombinant (rHuNRG1) Cell culture Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells. inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction. stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells. stimulating Schwann cell proliferation. implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 61 amino acids MW: 7.055 D Purity: >96% |
Biomol GmbH |
1 mg |
anfragen
|
| 94966.10 |
Neuregulin-1 beta2 / Heregulin-b2, human recombinant (rHuNRG1) Cell culture Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells. inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction. stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells. stimulating Schwann cell proliferation. implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 61 amino acids MW: 7.055 D |
Biomol GmbH |
10 µg |
66 €
|
| 94966.50 |
Neuregulin-1 beta2 / Heregulin-b2, human recombinant (rHuNRG1) Cell culture Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells. inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction. stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells. stimulating Schwann cell proliferation. implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 61 amino acids MW: 7.055 D |
Biomol GmbH |
50 µg |
170 €
|
| 97078.1 |
Interleukin-16, His Tag, human recombinant (rHuIL-16-His) Cell culture Interleukin-16 stimulates a migratory response in CD4 lymphocytes, monocytes, and eosinophils. Primes CD4 T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated polypeptide chain containing 150 amino acids and having a N-terminal His Tag Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 97078.25 |
Interleukin-16, His Tag, human recombinant (rHuIL-16-His) Cell culture Interleukin-16 stimulates a migratory response in CD4 lymphocytes, monocytes, and eosinophils. Primes CD4 T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated polypeptide chain containing 150 amino acids and having a N-terminal His Tag |
Biomol GmbH |
25 µg |
170 €
|
| 97078.5 |
Interleukin-16, His Tag, human recombinant (rHuIL-16-His) Cell culture Interleukin-16 stimulates a migratory response in CD4 lymphocytes, monocytes, and eosinophils. Primes CD4 T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated polypeptide chain containing 150 amino acids and having a N-terminal His Tag |
Biomol GmbH |
5 µg |
66 €
|
| 97081.1 |
Interleukin-16, human recombinant (rHuIL-16) Cell culture Interleukin-16 stimulates a migratory response in CD4 lymphocytes, monocytes, and eosinophils. Primes CD4 T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated polypeptide chain containing 130 amino acids Purity: >97% |
Biomol GmbH |
1 mg |
anfragen
|
| 97081.10 |
Interleukin-16, human recombinant (rHuIL-16) Cell culture Interleukin-16 stimulates a migratory response in CD4 lymphocytes, monocytes, and eosinophils. Primes CD4 T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated polypeptide chain containing 130 amino acids |
Biomol GmbH |
10 µg |
170 €
|
| 97081.2 |
Interleukin-16, human recombinant (rHuIL-16) Cell culture Interleukin-16 stimulates a migratory response in CD4 lymphocytes, monocytes, and eosinophils. Primes CD4 T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated polypeptide chain containing 130 amino acids |
Biomol GmbH |
2 µg |
66 €
|
| 86423.1 |
Nerve Growth Factor beta, human recombinant (rHubeta-NGF) Cell Culture Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. (www.uniprot.org) Produced in CHO. Homodimer, glycosylated, polypeptide chain containing 2 x 119 amino acids. The ED50, calculated by its ability to stimulate chick E9 DRG neurite outgrowth was found to be < 1.0 ng/ml. MW: 16.950 D Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 86423.20 |
Nerve Growth Factor beta, human recombinant (rHubeta-NGF) Cell Culture Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. (www.uniprot.org) Produced in CHO. Homodimer, glycosylated, polypeptide chain containing 2 x 119 amino acids. The ED50, calculated by its ability to stimulate chick E9 DRG neurite outgrowth was found to be < 1.0 ng/ml. MW: 16.950 D |
Biomol GmbH |
20 µg |
170 €
|
| 86423.5 |
Nerve Growth Factor beta, human recombinant (rHubeta-NGF) Cell Culture Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. (www.uniprot.org) Produced in CHO. Homodimer, glycosylated, polypeptide chain containing 2 x 119 amino acids. The ED50, calculated by its ability to stimulate chick E9 DRG neurite outgrowth was found to be < 1.0 ng/ml. MW: 16.950 D |
Biomol GmbH |
5 µg |
66 €
|
| 87319.1 |
Pro-Nerve Growth Factor, human recombinant (rHuPro-NGF) Cell Culture Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. (www.uniprot.org) Produced in E.coli. Homodimer, non-glycosylated, polypeptide chain containing 222 amino acids. The activity of the protein can by measured by its stimulating effect on the proliferation of TF1 cells. EC50 130 ± 30 pM (TF1 cell assay) MW: 49.738 D Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 87319.10 |
Pro-Nerve Growth Factor, human recombinant (rHuPro-NGF) Cell Culture Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. (www.uniprot.org) Produced in E.coli. Homodimer, non-glycosylated, polypeptide chain containing 222 amino acids. The activity of the protein can by measured by its stimulating effect on the proliferation of TF1 cells. EC50 130 ± 30 pM (TF1 cell assay) MW: 49.738 D |
Biomol GmbH |
10 µg |
170 €
|
| 87319.100 |
Pro-Nerve Growth Factor, human recombinant (rHuPro-NGF) Cell Culture Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. (www.uniprot.org) Produced in E.coli. Homodimer, non-glycosylated, polypeptide chain containing 222 amino acids. The activity of the protein can by measured by its stimulating effect on the proliferation of TF1 cells. EC50 130 ± 30 pM (TF1 cell assay) MW: 49.738 D |
Biomol GmbH |
100 µg |
anfragen
|
| 87319.2 |
Pro-Nerve Growth Factor, human recombinant (rHuPro-NGF) Cell Culture Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. (www.uniprot.org) Produced in E.coli. Homodimer, non-glycosylated, polypeptide chain containing 222 amino acids. The activity of the protein can by measured by its stimulating effect on the proliferation of TF1 cells. EC50 130 ± 30 pM (TF1 cell assay) MW: 49.738 D |
Biomol GmbH |
2 µg |
66 €
|
| 99852.1 |
Nerve Growth Factor beta, human recombinant (rHubeta-NGF) Cell culture Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. (www.uniprot.org) Produced in E.coli as a non-covalently disulfide-linked homodimer, non-glycosylated, polypeptide chain containing 2 identical chains of 121 amino acids each. MW: 13.500 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 99852.20 |
Nerve Growth Factor beta, human recombinant (rHubeta-NGF) Cell culture Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. (www.uniprot.org) Produced in E.coli as a non-covalently disulfide-linked homodimer, non-glycosylated, polypeptide chain containing 2 identical chains of 121 amino acids each. MW: 13.500 D |
Biomol GmbH |
20 µg |
170 €
|
| 99852.5 |
Nerve Growth Factor beta, human recombinant (rHubeta-NGF) Cell culture Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons. (www.uniprot.org) Produced in E.coli as a non-covalently disulfide-linked homodimer, non-glycosylated, polypeptide chain containing 2 identical chains of 121 amino acids each. MW: 13.500 D |
Biomol GmbH |
5 µg |
66 €
|
| 50439.1 |
Tumor Necrosis Factor beta, human recombinant (rHuTNF-b) Cell culture Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 171 amino acids. The ED50 as determined by the cytolysis of murine L929 cells in the presence of Actinomycin D is < 0.05ng/ml. MW: 18.650 D Purity: >98% |
Biomol GmbH |
1 mg |
anfragen
|
| 50439.20 |
Tumor Necrosis Factor beta, human recombinant (rHuTNF-b) Cell culture Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 171 amino acids. The ED50 as determined by the cytolysis of murine L929 cells in the presence of Actinomycin D is < 0.05ng/ml. MW: 18.650 D |
Biomol GmbH |
20 µg |
170 €
|
| 50439.5 |
Tumor Necrosis Factor beta, human recombinant (rHuTNF-b) Cell culture Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 171 amino acids. The ED50 as determined by the cytolysis of murine L929 cells in the presence of Actinomycin D is < 0.05ng/ml. MW: 18.650 D |
Biomol GmbH |
5 µg |
66 €
|
| 95027.1 |
Tumor Necrosis Factor beta, His Tag, human recombinant (rHuTNF-b-His) Cell biology studies Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 171 amino acids (fragment 35-205) with an amino-terminal hexahistidine tag. MW: 18.600 D Purity: >95% |
Biomol GmbH |
1 mg |
anfragen
|
| 95027.20 |
Tumor Necrosis Factor beta, His Tag, human recombinant (rHuTNF-b-His) Cell biology studies Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 171 amino acids (fragment 35-205) with an amino-terminal hexahistidine tag. MW: 18.600 D |
Biomol GmbH |
20 µg |
170 €
|
| 95027.5 |
Tumor Necrosis Factor beta, His Tag, human recombinant (rHuTNF-b-His) Cell biology studies Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 171 amino acids (fragment 35-205) with an amino-terminal hexahistidine tag. MW: 18.600 D |
Biomol GmbH |
5 µg |
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