Kontakt 0800-2466651 DE | EN Login Warenkorb



Produkttypen



Sonderbestellungen:


Spezifische Suchen:


8.972 Treffer print
ART-NR PRODUKT HERSTELLER MENGE PREIS
A300-023A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
MSH6 is a component of the DNA mismatch repair (MMR) system that functions to recognize base-base mismatches and framshift mispairs. MSH6 forms a heterodimer with MSH2 and is also part of the BRCA1-associated genome surveillance complex (BASC). Mutations in MSH6 have been linked to endometrial carcinoma. Alternate names for MSH6 include DNA mismatch repair protein MSH6, MutS-alpha 160 kDa subunit, G/T mismatch ?binding protein, GTBP, GTMBP, HSAP, and HNPCC5.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-023A maps to a region between residue 1300 and the C-terminus (residue 1360) of human MutS homolog 6 using the numbering given in entry NP_000170.1 (GeneID 2956).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €


A303-505A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Transcription initiation factor TFIID subunit 1 (TAF1) is the largest component and core scaffold of the TFIID basal transcription factor complex. TAF1 contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. TAF1 phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. It also phosphorylates GTF2A1 and GTF2F1 on Ser residues. TAF1 possesses DNA-binding activity and is essential for progression of the G1 phase of the cell cycle. Alternative names for TAF1 include cell cycle gene 1 protein, TBP-associated factor 250 kDa, p250, TAF(II)250, TAFII-250, TAFII250, BA2R, CCG1, CCGS, TAF2A. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P21675]

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A303-505A maps to a region between residue 1800 and 1850 of human Transcription Initiation Factor TFIID Subunit 1 using the numbering given in entry NP_620278.1 (GeneID 6872).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €


A302-539A
IP Erklärungen der Abkürzungen ansehen.
Major CDK9 elongation factor-associated protein (MCEF) is also known as AFF4 AF4/FMR2 family member 4. This family of proteins includes the AF4 proto-oncogene and FMR2 (fragile X E mental retardation syndrome) nuclear proteins. MCEF is a component of the cyclin-dependent kinase pair (CDK9/cyclin T1) complex. A chromosomal aberration involving AFF4 is found in acute lymphoblastic leukemia (ALL). Alternative names for MCEF include ALL1-fused gene from chromosome 5q31 protein, protein AF-5q31, and AF5Q31.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A302-539A maps to a region between residue 1113 and 1163 of human major CDK9 elongation factor-associated protein of human using the numbering given in entry NP_055238.1 (GeneID 27125).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €


A300-929A
related products

WB Erklärungen der Abkürzungen ansehen.
Protein arginine methylation is a form of post-translational modification that is catalyzed by protein arginine methyltransferases (PRMTs). HMGA1a (high mobility group A) has been identified as a substrate of PRMT6. The identification of HMGA1 as a substrate suggests that PRMT6 is involved in chromatin structure organization and gene regulation. PRMT6 is also known as protein arginine N-methyl transferase 6, heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6, HRMT1L6, and FLJ10559.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-929A maps to a region between residue 325 and the C-terminus (residue 375) of human Protein Arginine Methyltransferase 6 using the numbering given in entry AAK85733.1 (GeneID 55170).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €


A301-472A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
TRAP100/MED24 is a component of the multisubunit mediator complex that functions as an interface between gene-specific transcription factors and the RNA Pol II/general transcription factor machinery. The mediator complex was first identified as a coactivator of the thyroid hormone receptor and has since been observed to function as a coactivator of a variety of transcription factors. TRAP100/MED24 associates with mediator subunit TRAP220. Both are essential to mouse development and play a role in androgen receptor-mediated transcription. Studies in zebrafish have shown that TRAP100/MED24 is also important to retinal development. Alternate names for TRAP100/MED24 include mediator of RNA polymerase II transcription subunit 24, mediator complex 24, thyroid hormone receptor-associated protein complex 100 kDa component, thyroid hormone receptor-associated protein 4, vitamin D3 receptor-interacting protein complex component DRIP100, ARC100, CRSP complex subunit 4, THRAP4, MGC8748, and KIAA0130.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A301-472A maps to a region between residue 939 and 989 of human thyroid hormone receptor-associated protein complex 100 kDa component (mediator complex subunit 24 ) using the numbering given in entry NP_055630.
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €


A301-991A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
Casein Kinase I alpha (CKI alpha) is a serine/threonine protein kinase involved in the wnt signaling pathway. It is part of the CK1 serine/threonine kinase family which includes CK1 alpha, CK1beta, CK1delta, CK1epsilon, and CK1gamma.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A301-991A maps to a region between residue 287 and 337 of human casein kinase 1 alpha 1 using the numbering given in entry NP_001883.4 (GeneID 1452).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €


A300-747A
related products

WB Erklärungen der Abkürzungen ansehen.
ZCH13 is an uncharacterized zinc-finger CCCH-type containing protein. Zinc-finger modules have been shown to be involved in nucleic acid binding, protein-protein interactions, and binding of small ligands. Alternate names for ZCH13 include zinc finger CCCH-type containing 13, KIAA0853, and FLJ35669.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-747A maps to a region between residue 15 and 75 of human Zinc Finger CCCH-type Containing 13 using the numbering given in entry NP_055885.2 (GeneID 23091).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €


A301-407A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
KANK2/SIP was first identified during a genome wide-screen for proteins that interact with the SRC transcriptional coactivator. KANK2/SIP was also identified by domain and phylogenetic analysis to be a member of the KANK ankyrin-repeat domain-containing protein family. KANK related proteins possess a conserved ankyrin-repeat and coiled-coil domain. KANK2, as well as other KANK proteins, appear to play a role in the formation of actin stress fibers. Alternate names for KANK2/SIP include KN motif and ankyrin repeat domain-containing protein 2, SRC-1-interacting protein, matrix-remodeling-associated protein 3, ankyrin repeat domain 25, ANKRD25, MXRA3, and KIAA1518.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-407A maps to a region between residue 550 and 600 of human KN motif and ankyrin repeat domains 2 (SRC-1 interacting protein) using the numbering given in entry NP_056308.2 (GeneID 25959).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €


A302-427A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Poly(A) polymerase gamma (PAP-gamma) is a member of the poly(A) polymerase family which catalyzes template-independent extension of the 3 end of a DNA/RNA strand. This enzyme shares 60 percent identity to the well characterized poly(A) polymerase II (PAPII) at the amino acid level. These two enzymes have similar organization of structural and functional domains. PAP-gamma is exclusively localized in the nucleus and exhibits nonspecific as well as CPSF (cleavage and polyadenylation specificity factor)/AAUAAA-dependent polyadenylation activity. Alternative names for PAP gamma include polynucleotide adenylyltransferase gamma, SRP RNA 3 -adenylating enzyme, neo-poly(A) polymerase, Neo-PAP, PAPOLG, PAP2, and PAPG.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A302-427A maps to a region between residue 686 and 736 of human poly(A) polymerase gamma using the numbering given in entry NP_075045.2 (GeneID 64895).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €


A310-513A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A301-473A and A301-474A

Rabbit SR: human
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €


A301-529A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
ZNF295 bears 8 C2H2-type zinc fingers and a BTB/POZ (broad-complex, tramtrack, bric a brac/ Pox-virus and zinc finger) domain indicating a function in transcriptional regulation. ZNF295 has been shown to function as a transcriptional repressor and associates with ZFP161, a zinc-finger protein also know to function as a repressor of transcription. Alternate name for ZNF295 include zinc-finger protein 295, zinc finger and BTB domain-containing protein 21, ZBTB21, and KIAA1227.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-529A maps to a region between residue 1016 and 1066 of human zinc finger protein 295 using the numbering given in entry NP_065778.3 (GeneID 49854).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €


A302-632A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
WDR11 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The WDR11 gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10,19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus. Alternative names for WDR11 include bromodomain and WD repeat-containing 2, BRWD2, and KIAA1351.[taken from NCBI Entrez Gene (GeneID: 55717)]

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A302-632A maps to a region between residue 1174 and 1224 of human WD repeat domain 11 using the numbering given in entry NP_060587.8 (GeneID 55717).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €


A10-113A
related products

ELISA, WB, IHC, ICC Erklärungen der Abkürzungen ansehen.
Sheep IgG SR: bovine
Bethyl
Icon Datasheet
1 mg

Buy Bulk

87 €


A80-109A
related products

ELISA, WB, IHC, ICC Erklärungen der Abkürzungen ansehen.
Format - Whole IgG

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 mg

Buy Bulk

174 €


A90-616AP
related products

ELISA, WB, IHC, ICC Erklärungen der Abkürzungen ansehen.
Whole IgG

Goat IgG SR: mouse
Bethyl
Icon Datasheet
500 µg

Buy Bulk

117 €


E11-118
ELISA Erklärungen der Abkürzungen ansehen.
Sandwich ELISA. Complete kit for quantitating Bovine IgG levels in serum, plasma, milk and colostrum. For up to 40 samples, tested in duplicate.
Bethyl
Icon Datasheet
manual
1 kit

Buy Bulk

551 €


A303-965A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
The androgen receptor (AR) functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes [taken from NCBI Entrez Gene (Gene ID: 367)].

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A303-965A maps to a region between residue 1 to 50 of human Androgen Receptor using the numbering given in entry NP_000035.2 (GeneID 367).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-966A
IP Erklärungen der Abkürzungen ansehen.
The androgen receptor (AR) functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes [taken from NCBI Entrez Gene (Gene ID: 367)].

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A303-966A maps to a region between residue 870 to 920 of human Androgen Receptor using the numbering given in entry NP_000035.2 (GeneID 367).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A311-436A
WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A303-965A and A303-966A

Rabbit IgG SR: human
Immunogen: synthetic peptide. Antibodies were affinity purified using epitopes specific to Androgen Receptor immobilized on solid support.
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A300-247A
related products

WB, IP, FC, PLA Erklärungen der Abkürzungen ansehen.
p53 is a tumor suppressor protein that is mutated or inactivated in over 50 percent of human cancers. Loss of function defects in p53 are the cause of the autosomal dominant familial cancer syndrome, Li-Fraumeni syndrome (LFS) that is characterized by the development of a diverse set of malignancies at very early ages. At the cellular level p53 is involved in the negative regulation of cell the cycle via its transactivational control of genes required for cell cycle progression. Depending on the physiological circumstance, p53 can promote growth arrest or apoptosis. Alternate names for p53 include cellular tumor antigen p53, tumor suppressor p53, phosphoprotein p53, antigen NY-CO-13, TP53, TRP53, and Li-Fraumeni syndrome.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-247A maps to a region between residues 50 and 100 of human tumor protein p53 using the numbering given in SwissProt entry P04637 (GeneID 7157).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-248A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
p53 is a tumor suppressor protein that is mutated or inactivated in over 50 percent of human cancers. Loss of function defects in p53 are the cause of the autosomal dominant familial cancer syndrome, Li-Fraumeni syndrome (LFS) that is characterized by the development of a diverse set of malignancies at very early ages. At the cellular level p53 is involved in the negative regulation of cell the cycle via its transactivational control of genes required for cell cycle progression. Depending on the physiological circumstance, p53 can promote growth arrest or apoptosis. Alternate names for p53 include cellular tumor antigen p53, tumor suppressor p53, phosphoprotein p53, antigen NY-CO-13, TP53, TRP53, and Li-Fraumeni syndrome.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-248A maps to a region between residues 325 and 375 of human tumor protein p53 using the numbering given in SwissProt entry P04637 (GeneID 7157).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-249A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
p53 is a tumor suppressor protein that is mutated or inactivated in over 50 percent of human cancers. Loss of function defects in p53 are the cause of the autosomal dominant familial cancer syndrome, Li-Fraumeni syndrome (LFS) that is characterized by the development of a diverse set of malignancies at very early ages. At the cellular level p53 is involved in the negative regulation of cell the cycle via its transactivational control of genes required for cell cycle progression. Depending on the physiological circumstance, p53 can promote growth arrest or apoptosis. Alternate names for p53 include cellular tumor antigen p53, tumor suppressor p53, phosphoprotein p53, antigen NY-CO-13, TP53, TRP53, and Li-Fraumeni syndrome.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-249A maps to a region between residues 375 and the C-terminus (residue 393) of human tumor protein p53 using the numbering given in SwissProt entry P04637 (GeneID 7157).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-068A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to p53 immobilized on solid support.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

729 €

IHC-00010
IHC Erklärungen der Abkürzungen ansehen.
p53 is a tumor suppressor protein that is mutated or inactivated in over 50 percent of human cancers. Loss of function defects in p53 are the cause of the autosomal dominant familial cancer syndrome, Li-Fraumeni syndrome (LFS) that is characterized by the development of a diverse set of malignancies at very early ages. At the cellular level p53 is involved in the negative regulation of cell the cycle via its transactivational control of genes required for cell cycle progression. Depending on the physiological circumstance, p53 can promote growth arrest or apoptosis. Alternate names for p53 include cellular tumor antigen p53, tumor suppressor p53, phosphoprotein p53, antigen NY-CO-13, TP53, TRP53, and Li-Fraumeni syndrome.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00010P maps to a region between residue 50 and 100 of human tumor protein p53 using the numbering given in entry NP 000537.2 (GeneID 7157).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A303-712A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
The insulin receptor is a receptor tyrosine kinase that mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates to stimulate uptake of glucose. The insulin receptor is synthesized as a single polypeptide that is cleaved to generate an alpha and beta subunit. The subunit structure of the insulin receptor consists of a tetramer of two alpha and two beta chains linked by disulfide bonds. Alternative names for insulin receptor include CD220, INSR, and HHF5.

Rabbit IgG SR: human, mouse
Immunogen: Synthetic peptide. The epitope recognized by A303-712A maps to a region between residue 1332 and 1382 of human Insulin Receptor, beta Subunit using the numbering given in entry NP_000199.2 (GeneID 3643).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-020A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
MSH2 is an integral component of the DNA mismatch repair (MMR) system that functions to recognize aberrant structures and signals for the repair of single base mismatches or loops in replicated DNA. MSH2 has also been demonstrated to function as an anti-recombinase and may play a role in negatively regulating DNA repair. MSH2 can heterodimerize with MSH3 or MSH6. Mutations in MSH2 are linked to hereditary nonpolyposis colon cancer (HNPCC). Alternate names for MSH2 include DNA mismatch repair protein Msh2, MutS protein homolog 2, MSH2, FCC1, COCA1, HNPCC, and HNPCC1.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-020A maps to a region between residues 1 and 50 of human mutS homolog 2 using the numbering given in Swiss-Prot entry P43246 (GeneID 4436).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-451A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
MSH2 is an integral component of the DNA mismatch repair (MMR) system that functions to recognize aberrant structures and signals for the repair of single base mismatches or loops in replicated DNA. MSH2 has also been demonstrated to function as an anti-recombinase and may play a role in negatively regulating DNA repair. MSH2 can heterodimerize with MSH3 or MSH6. Mutations in MSH2 are linked to hereditary nonpolyposis colon cancer (HNPCC). Alternate names for MSH2 include DNA mismatch repair protein Msh2, MutS protein homolog 2, MSH2, FCC1, COCA1, HNPCC, and HNPCC1.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-451A maps to a region between residues 1 and 50 of human mutS homolog 2 using the numbering given in Swiss-Prot entry P43246 (GeneID 4436).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-452A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
MSH2 is an integral component of the DNA mismatch repair (MMR) system that functions to recognize aberrant structures and signals for the repair of single base mismatches or loops in replicated DNA. MSH2 has also been demonstrated to function as an anti-recombinase and may play a role in negatively regulating DNA repair. MSH2 can heterodimerize with MSH3 or MSH6. Mutations in MSH2 are linked to hereditary nonpolyposis colon cancer (HNPCC). Alternate names for MSH2 include DNA mismatch repair protein Msh2, MutS protein homolog 2, MSH2, FCC1, COCA1, HNPCC, and HNPCC1.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-452A maps to a region between residue 875 and the C-terminus (residue 934) of human mutS homolog 2 using the numbering given in Swiss-Prot entry P43246 (GeneID 4436).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-127A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to MSH2 immobilized on solid support.

Rabbit IgG SR: human, mouse
Bethyl
Icon Datasheet
1 pack

Buy Bulk

729 €

IHC-00082
IHC Erklärungen der Abkürzungen ansehen.
MSH2 is an integral component of the DNA mismatch repair (MMR) system that functions to recognize aberrant structures and signals for the repair of single base mismatches or loops in replicated DNA. MSH2 has also been demonstrated to function as an anti-recombinase and may play a role in negatively regulating DNA repair. MSH2 can heterodimerize with MSH3 or MSH6. Mutations in MSH2 are linked to hereditary nonpolyposis colon cancer (HNPCC). Alternate names for MSH2 include DNA mismatch repair protein Msh2, MutS protein homolog 2, MSH2, FCC1, COCA1, HNPCC, and HNPCC1.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by IHC-00082 maps to a region between residue 875 and the C-terminus (residue 934) of human mutS homolog 2 using the numbering given in Swiss-Prot entry P43246 (GeneID 4436).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

S300-020
IP Erklärungen der Abkürzungen ansehen.
Rabbit anti-human MSH2 affinity purified Antibodies were coupled to agarose beads using a cyanogen bromide method.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
100 µg

Buy Bulk

367 €

A300-015A
related products

WB, IP, IHC, PLA Erklärungen der Abkürzungen ansehen.
MLH1 is an integral component of the DNA mismatch repair (MMR) system that might function to recruit DNA repair proteins to the mismatch repair complex. MLH1 is located at a chromosomal location identified as an important candidate in HNPCC (hereditary nonpolyposis colorectal cancer). MLH1 is part of the BRCA1-associated genome surveillance complex (BASC). Alternate names for MLH1 include DNA mismatch repair protein Mlh1, MutL protein homolog 1, COCA2, FCC2, HNPCC, HNPCC2, and MGC5172.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-015A maps to a region between residue 700 and the C-terminus (residue 756) of human mutL homolog 1 using the numbering given in entry NP_000240.1 (GeneID 4292).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

S300-015
IP Erklärungen der Abkürzungen ansehen.
Rabbit anti-human MLH1 affinity purified Antibodies were coupled to agarose beads using a cyanogen bromide method.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
100 µg

Buy Bulk

367 €

A303-430A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Lamin A/C plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Alternative names for Lamin A/C include 70 kDa lamin, renal carcinoma antigen NY-REN-32, prelamin-A/C, LMNA, LMN1. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P02545].

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A303-430A maps to a region between residue 1 and 50 of human Lamin A/Lamin C using the numbering given in entry NP_733821.1 (GeneID 4000).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-431A
related products

WB Erklärungen der Abkürzungen ansehen.
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Lamin A/C plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Alternative names for Lamin A/C include 70 kDa lamin, renal carcinoma antigen NY-REN-32, prelamin-A/C, LMNA, LMN1. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P02545].

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A303-431A maps to a region between residue 150 and 200 of human Lamin A/Lamin C using the numbering given in entry NP_733821.1 (GeneID 4000).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-432A
related products

WB Erklärungen der Abkürzungen ansehen.
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Lamin A/C plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Alternative names for Lamin A/C include 70 kDa lamin, renal carcinoma antigen NY-REN-32, prelamin-A/C, LMNA, LMN1. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P02545].

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A303-432A maps to a region between residue 400 and 450 of human Lamin A using the numbering given in entry NP_733821.1 (GeneID 4000).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-433A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Lamin A/C plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Alternative names for Lamin A/C include 70 kDa lamin, renal carcinoma antigen NY-REN-32, prelamin-A/C, LMNA, LMN1. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P02545].

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A303-433A maps to a region between residue 550 and 600 of human Lamin A using the numbering given in entry NP_733821.1 (GeneID 4000).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A311-266A
WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A303-430A, A303-431A, A303-432A and A303-433A

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

966 €

A300-495A
IP Erklärungen der Abkürzungen ansehen.
Estrogen receptor-related alpha (ERRA) is a nuclear orphan receptor structurally related to the estrogen receptor (ER). ERRA and ERalpha share approximately 68 percent sequence identity in their DNA binding domain and 33 percent in their ligand-binding domain. There is evidence that ERRA and ERalpha bind similar promoter elements and that ERRA can activate ERalpha targets in the absence of estrogen. Additional names for ERRA include estrogen receptor like 1, nuclear receptor subfamily 3 group B member 1, ERRalpha, ESRRA, ERR1, ESRL1, and NR3B1.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-495A maps to a region between residues 1 and 50 of human Estrogen Receptor Alpha using the numbering given in SwissProt entry P03372 (GeneID 2099).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-496A
IP Erklärungen der Abkürzungen ansehen.
Estrogen receptor-related alpha (ERRA) is a nuclear orphan receptor structurally related to the estrogen receptor (ER). ERRA and ERalpha share approximately 68 percent sequence identity in their DNA binding domain and 33 percent in their ligand-binding domain. There is evidence that ERRA and ERalpha bind similar promoter elements and that ERRA can activate ERalpha targets in the absence of estrogen. Additional names for ERRA include estrogen receptor like 1, nuclear receptor subfamily 3 group B member 1, ERRalpha, ESRRA, ERR1, ESRL1, and NR3B1.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-496A maps to a region between residues 100 and 150 of human Estrogen Receptor Alpha using the numbering given in SwissProt entry P03372 (GeneID 2099).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-497A
IP Erklärungen der Abkürzungen ansehen.
Estrogen receptor-related alpha (ERRA) is a nuclear orphan receptor structurally related to the estrogen receptor (ER). ERRA and ERalpha share approximately 68 percent sequence identity in their DNA binding domain and 33 percent in their ligand-binding domain. There is evidence that ERRA and ERalpha bind similar promoter elements and that ERRA can activate ERalpha targets in the absence of estrogen. Additional names for ERRA include estrogen receptor like 1, nuclear receptor subfamily 3 group B member 1, ERRalpha, ESRRA, ERR1, ESRL1, and NR3B1.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-497A maps to a region between residues 525 and 575 of human Estrogen Receptor Alpha using the numbering given in SwissProt entry P03372 (GeneID 2099).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-498A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Estrogen receptor-related alpha (ERRA) is a nuclear orphan receptor structurally related to the estrogen receptor (ER). ERRA and ERalpha share approximately 68 percent sequence identity in their DNA binding domain and 33 percent in their ligand-binding domain. There is evidence that ERRA and ERalpha bind similar promoter elements and that ERRA can activate ERalpha targets in the absence of estrogen. Additional names for ERRA include estrogen receptor like 1, nuclear receptor subfamily 3 group B member 1, ERRalpha, ESRRA, ERR1, ESRL1, and NR3B1.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-498A maps to a region between residue 550 and the C-terminus (residue 595) of human Estrogen Receptor Alpha using the numbering given in SwissProt entry P03372 (GeneID 2099).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-598A
related products

WB Erklärungen der Abkürzungen ansehen.
Estrogen receptor-related alpha (ERRA) is a nuclear orphan receptor structurally related to the estrogen receptor (ER). ERRA and ERalpha share approximately 68 percent sequence identity in their DNA binding domain and 33 percent in their ligand-binding domain. There is evidence that ERRA and ERalpha bind similar promoter elements and that ERRA can activate ERalpha targets in the absence of estrogen. Additional names for ERRA include estrogen receptor like 1, nuclear receptor subfamily 3 group B member 1, ERRalpha, ESRRA, ERR1, ESRL1, and NR3B1.

Rabbit IgG SR: human
Immunogen: synthetic phospho-peptide. Immunogen for A300-598A was a phosphorylated synthetic peptide, which represented a portion of human Estrogen Receptor Alpha (GeneID 2099) around serine 305 according to the numbering given in entry NP_000116.2.
Bethyl
Icon Datasheet
100 µl

Buy Bulk

373 €

A310-143A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to Estrogen Receptor Alpha immobilized on solid support.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

966 €

IHC-00006
IHC Erklärungen der Abkürzungen ansehen.
The estrogen receptor (ER) is the steroid-hormone nuclear receptor that binds estrogen and functions to activate genes involved in a variety of biological processes. Two forms of the ER, ER alpha and ER beta, are encoded by independent genes, and each plays different roles in gene regulation. Additional variants of ER beta have also been reported, these include ERb2, ERb3, ERb4, and ERb5. All forms of the ER have the ability to heterodimerize with each other. Differences in localization and concentrations as well as heterodimerization among the variants may serve to achieve distinct cell and tissue responses. ER alpha generally functions as an activator of transcription while ER beta functions as a repressor. Alternate names for ER alpha include estradiol receptor, ESR1, ER, Era, NR3A1, and DKFZp686N23123.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00006 maps to a region between residue 550 and the C-terminus (residue 595) of human Estrogen Receptor Alpha using the numbering given in SwissProt entry P03372 (GeneID 2099).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A300-387A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
The epidermal growth factor receptor (EGFR) is a membrane spanning tyrosine kinase receptor for epidermal growth factor (EGF) and other ligands of the EGF family such as TGF-alpha, amphiregulin, betacellulin, epiregulin and heparin-binding EGF-like growth factor. Upon ligand binding, the EGFR homodimerizes or heterodimerizes with other ErbB receptor family members and tranduces a downstream signal via the ras-raf-mitogen activated protein kinase pathway or the phosphatidylinositol 3-kinase (PI3K)/Akt pathway. Signals from the EGFR function to influence cell proliferation, differentiation, and development. Alternate names for EGFR include receptor tyrosine-protein kinase ErbB-1, ERBB1, ERBB, and mENA.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-387A maps to a region between residues 1100 and 1150 of human Epidermal Growth Factor Receptor using the numbering given in Swiss-Prot entry P00533 (GeneID 1956).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-388A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
The epidermal growth factor receptor (EGFR) is a membrane spanning tyrosine kinase receptor for epidermal growth factor (EGF) and other ligands of the EGF family such as TGF-alpha, amphiregulin, betacellulin, epiregulin and heparin-binding EGF-like growth factor. Upon ligand binding, the EGFR homodimerizes or heterodimerizes with other ErbB receptor family members and tranduces a downstream signal via the ras-raf-mitogen activated protein kinase pathway or the phosphatidylinositol 3-kinase (PI3K)/Akt pathway. Signals from the EGFR function to influence cell proliferation, differentiation, and development. Alternate names for EGFR include receptor tyrosine-protein kinase ErbB-1, ERBB1, ERBB, and mENA.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-388A maps to a region between residue 1150 and the C-terminus (residue 1210) of human Epidermal Growth Factor Receptor using the numbering given in Swiss-Prot entry P00533 (GeneID 1956).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-105A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to EGFR immobilized on solid support.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

IHC-00005
IHC Erklärungen der Abkürzungen ansehen.
The epidermal growth factor receptor (EGFR) is a membrane spanning tyrosine kinase receptor for epidermal growth factor (EGF) and other ligands of the EGF family such as TGF-alpha, amphiregulin, betacellulin, epiregulin and heparin-binding EGF-like growth factor. Upon ligand binding, the EGFR homodimerizes or heterodimerizes with other ErbB receptor family members and tranduces a downstream signal via the ras-raf-mitogen activated protein kinase pathway or the phosphatidylinositol 3-kinase (PI3K)/Akt pathway. Signals from the EGFR function to influence cell proliferation, differentiation, and development. Alternate names for EGFR include receptor tyrosine-protein kinase ErbB-1, ERBB1, ERBB, and mENA.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by IHC-00005 maps to a region between residue 1150 and the C-terminus (residue 1210) of human Epidermal Growth Factor Receptor using the numbering given in SwissProt entry P00533 (GeneID 1956).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A301-167A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
PML is a member of RBCC/TRIM family of proteins that possess a RING finger domain, B-box, and coiled-coil domain. PML is a multifunctional protein involved in activities such as tumor growth suppression, hematopoietic differentiation, gene transcription, apoptotic induction, and viral immunity. PML is often involved in chromosomal translocations with the retinoic acid receptor alpha gene. PML-retinoic acid receptor translocations are associated with acute promyelocytic leukemia. Alternate names for PML include probable transcription factor PML, tripartite motif-containing protein 19, RING finger protein 71, MYL, RNF71, TRIM19, and PP8675.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-167A maps to a region between residue 375 and 425 of promyelocytic leukemia using the numbering given in entry NP_150241.2 (GeneID 5371).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-168A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
PML is a member of RBCC/TRIM family of proteins that possess a RING finger domain, B-box, and coiled-coil domain. PML is a multifunctional protein involved in activities such as tumor growth suppression, hematopoietic differentiation, gene transcription, apoptotic induction, and viral immunity. PML is often involved in chromosomal translocations with the retinoic acid receptor alpha gene. PML-retinoic acid receptor translocations are associated with acute promyelocytic leukemia. Alternate names for PML include probable transcription factor PML, tripartite motif-containing protein 19, RING finger protein 71, MYL, RNF71, TRIM19, and PP8675.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-168A maps to a region between residue 575 and 625 of promyelocytic leukemia using the numbering given in entry NP_150241.2 (GeneID 5371).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-390A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A301-167A and A301-168A

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

IHC-00241
IHC Erklärungen der Abkürzungen ansehen.
PML is a member of RBCC/TRIM family of proteins that possess a RING finger domain, B-box, and coiled-coil domain. PML is a multifunctional protein involved in activities such as tumor growth suppression, hematopoietic differentiation, gene transcription, apoptotic induction, and viral immunity. PML is often involved in chromosomal translocations with the retinoic acid receptor alpha gene. PML-retinoic acid receptor translocations are associated with acute promyelocytic leukemia. Alternate names for PML include probable transcription factor PML, tripartite motif-containing protein 19, RING finger protein 71, MYL, RNF71, TRIM19, and PP8675.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00241 maps to a region between residue 375 and 425 of promyelocytic leukemia using the numbering given in entry NP_150241.2 (GeneID 5371).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A300-000A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination. BRCA1 is also known as breast cancer type 1 susceptibility protein, RING finger protein 53, RNF53, IRIS, PSCP, BRCAI, and BRCC1.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-000A maps to a region between residue 1800 and the C-terminus (residue 1863) of human Breast Cancer Gene 1 using the numbering given in entry NP_009225.1 (GeneID 672).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-001A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination. BRCA1 is also known as breast cancer type 1 susceptibility protein, RING finger protein 53, RNF53, IRIS, PSCP, BRCAI, and BRCC1.

Rabbit IgG SR: human
Immunogen: synthetic phospho-peptide. Immunogen for A300-001A was a phosphorylated synthetic peptide, which represented a portion of human Breast Cancer Gene 1 (GeneID 672) around serine 1524 according to the numbering given in entry NP_009225.1.
Bethyl
Icon Datasheet
100 µl

Buy Bulk

373 €

A300-003A
related products

WB Erklärungen der Abkürzungen ansehen.
BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination. BRCA1 is also known as breast cancer type 1 susceptibility protein, RING finger protein 53, RNF53, IRIS, PSCP, BRCAI, and BRCC1.

Rabbit IgG SR: human
Immunogen: synthetic phospho-peptide. Immunogen for A300-003A was a phosphorylated synthetic peptide, which represented a portion of human Breast Cancer Gene 1 (GeneID 672) around serine 1189 according to the numbering given in entry NP_009225.1.
Bethyl
Icon Datasheet
100 µl

Buy Bulk

373 €

A300-004A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination. BRCA1 is also known as breast cancer type 1 susceptibility protein, RING finger protein 53, RNF53, IRIS, PSCP, BRCAI, and BRCC1.

Rabbit IgG SR: human
Immunogen: synthetic phospho-peptide. Immunogen for A300-004A was a phosphorylated synthetic peptide, which represented a portion of human Breast Cancer Gene 1 (GeneID 672) around serine 1280 according to the numbering given in entry NP_009225.1.
Bethyl
Icon Datasheet
100 µl

Buy Bulk

373 €

A300-007A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination. BRCA1 is also known as breast cancer type 1 susceptibility protein, RING finger protein 53, RNF53, IRIS, PSCP, BRCAI, and BRCC1.

Rabbit IgG SR: human
Immunogen: synthetic phospho-peptide. Immunogen for A300-007A was a phosphorylated synthetic peptide, which represented a portion of human Breast Cancer Gene 1 (GeneID 672) around serine 1387 according to the numbering given in entry NP_009225.1.
Bethyl
Icon Datasheet
100 µl

Buy Bulk

373 €

A300-008A
related products

WB Erklärungen der Abkürzungen ansehen.
BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination. BRCA1 is also known as breast cancer type 1 susceptibility protein, RING finger protein 53, RNF53, IRIS, PSCP, BRCAI, and BRCC1.

Rabbit IgG SR: human
Immunogen: synthetic phospho-peptide. Immunogen for A300-008A was a phosphorylated synthetic peptide, which represented a portion of human Breast Cancer Gene 1 (GeneID 672) around serine 1423 according to the numbering given in entry NP_009225.1.
Bethyl
Icon Datasheet
100 µl

Buy Bulk

373 €

A300-009A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination. BRCA1 is also known as breast cancer type 1 susceptibility protein, RING finger protein 53, RNF53, IRIS, PSCP, BRCAI, and BRCC1.

Rabbit IgG SR: human
Immunogen: synthetic phospho-peptide. Immunogen for A300-009A was a phosphorylated synthetic peptide, which represented a portion of human Breast Cancer Gene 1 (GeneID 672) around serine 1457 according to the numbering given in entry NP_009225.1.
Bethyl
Icon Datasheet
100 µl

Buy Bulk

373 €

A300-011A
related products

WB Erklärungen der Abkürzungen ansehen.
BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination. BRCA1 is also known as breast cancer type 1 susceptibility protein, RING finger protein 53, RNF53, IRIS, PSCP, BRCAI, and BRCC1.

Rabbit IgG SR: human
Immunogen: synthetic phospho-peptide. Immunogen for A300-011A was a phosphorylated synthetic peptide, which represented a portion of human Breast Cancer Gene 1 (GeneID 672) around serine 1466 according to the numbering given in entry NP_009225.1.
Bethyl
Icon Datasheet
100 µl

Buy Bulk

373 €

A301-377A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination. BRCA1 is also known as breast cancer type 1 susceptibility protein, RING finger protein 53, RNF53, IRIS, PSCP, BRCAI, and BRCC1.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-377A maps to a region between residue 250 and 300 of human breast cancer 1 using the numbering given in entry NP_009225.1 (GeneID 672).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-378A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination. BRCA1 is also known as breast cancer type 1 susceptibility protein, RING finger protein 53, RNF53, IRIS, PSCP, BRCAI, and BRCC1.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-378A maps to a region between residue 700 and 750 of human breast cancer 1 using the numbering given in entry NP_009225.1 (GeneID 672).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-477A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A300-000A, A301-377A and A301-378A

Rabbit IgG SR: human
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

729 €

IHC-00278
IHC Erklärungen der Abkürzungen ansehen.
BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination. BRCA1 is also known as breast cancer type 1 susceptibility protein, RING finger protein 53, RNF53, IRIS, PSCP, BRCAI, and BRCC1.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00278 maps to a region between residue 700 and 750 of human breast cancer 1 using the numbering given in entry NP_009225.1 (GeneID 672).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

S300-000
IP Erklärungen der Abkürzungen ansehen.
Rabbit anti-human BRCA1 affinity purified Antibodies were coupled to agarose beads using a cyanogen bromide method.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
100 µg

Buy Bulk

367 €

A300-135A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Ataxia telangiectasia, mutated (ATM) is the gene responsible for the neurodegenerative disease ataxia telangiectasia (AT). AT is characterized by neurodegeneration, immune dysfunction, sensitivity to DNA damage, and cancer predisposition. ATM is a protein kinase central to the DNA damage response. In response to DNA double-strand breaks (DSBs), ATM initiates a signaling cascade that involves the phosphorylation of a multitude of substrates which include p53, BRCA1, p53 binding protein, CHK2, RAD9, RAD17, and MDM4. Alternate names for ATM include AT1, ATA, ATC, ATD, ATE, ATDC, TEL1, TELO1, MGC74674, Serine protein kinase ATM, human phosphatidylinositol 3 kinase homolog, AT protein, and DKFZp781A0353.

Goat IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-135A maps to a region between residues 1750 and 1800 of human Ataxia Telangiectasia Mutated using the numbering given in entry NP_000042.2 (GeneID 472).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-136A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
Ataxia telangiectasia, mutated (ATM) is the gene responsible for the neurodegenerative disease ataxia telangiectasia (AT). AT is characterized by neurodegeneration, immune dysfunction, sensitivity to DNA damage, and cancer predisposition. ATM is a protein kinase central to the DNA damage response. In response to DNA double-strand breaks (DSBs), ATM initiates a signaling cascade that involves the phosphorylation of a multitude of substrates which include p53, BRCA1, p53 binding protein, CHK2, RAD9, RAD17, and MDM4. Alternate names for ATM include AT1, ATA, ATC, ATD, ATE, ATDC, TEL1, TELO1, MGC74674, Serine protein kinase ATM, human phosphatidylinositol 3 kinase homolog, AT protein, and DKFZp781A0353.

Goat IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-136A maps to a region between residues 2550 and 2600 of human Ataxia Telangiectasia Mutated using the numbering given in entry NP_000042.2 (GeneID 472).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-299A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
Ataxia telangiectasia, mutated (ATM) is the gene responsible for the neurodegenerative disease ataxia telangiectasia (AT). AT is characterized by neurodegeneration, immune dysfunction, sensitivity to DNA damage, and cancer predisposition. ATM is a protein kinase central to the DNA damage response. In response to DNA double-strand breaks (DSBs), ATM initiates a signaling cascade that involves the phosphorylation of a multitude of substrates which include p53, BRCA1, p53 binding protein, CHK2, RAD9, RAD17, and MDM4. Alternate names for ATM include AT1, ATA, ATC, ATD, ATE, ATDC, TEL1, TELO1, MGC74674, Serine protein kinase ATM, human phosphatidylinositol 3 kinase homolog, AT protein, and DKFZp781A0353.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-299A maps to a region between residues 2550 and 2600 of human ataxia telangiectasia mutated using the numbering given in SwissProt entry Q13315 (GeneID 472).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-034A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to ATM immobilized on solid support.

Rabbit IgG SR: human, mouse
Bethyl
Icon Datasheet
1 pack

Buy Bulk

729 €

IHC-00034
IHC Erklärungen der Abkürzungen ansehen.
Ataxia telangiectasia, mutated (ATM) is the gene responsible for the neurodegenerative disease ataxia telangiectasia (AT). AT is characterized by neurodegeneration, immune dysfunction, sensitivity to DNA damage, and cancer predisposition. ATM is a protein kinase central to the DNA damage response. In response to DNA double-strand breaks (DSBs), ATM initiates a signaling cascade that involves the phosphorylation of a multitude of substrates which include p53, BRCA1, p53 binding protein, CHK2, RAD9, RAD17, and MDM4. Alternate names for ATM include AT1, ATA, ATC, ATD, ATE, ATDC, TEL1, TELO1, MGC74674, Serine protein kinase ATM, human phosphatidylinositol 3 kinase homolog, AT protein, and DKFZp781A0353.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00034 maps to a region between residue 2550 and 2600 of human ataxia telangiectasia mutated using the numbering given in SwissProt entry Q13315 (GeneID 472).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

S300-135
IP Erklärungen der Abkürzungen ansehen.
Goat anti-human ATM affinity purified Antibodies were coupled to agarose beads using a cyanogen bromide method.

Goat IgG SR: human, mouse
Bethyl
Icon Datasheet
100 µg

Buy Bulk

367 €

S300-136
IP Erklärungen der Abkürzungen ansehen.
Goat anti-human ATM affinity purified Antibodies were coupled to agarose beads using a cyanogen bromide method.

Goat IgG SR: human, mouse
Bethyl
Icon Datasheet
100 µg

Buy Bulk

367 €

A300-687A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Sirt1 is one of seven members of the sirtuin family of proteins that are homologous to the yeast silent information regulator 2 (Sir2), a NADplus-dependent protein deacetylase that plays a role in lifespan in lower eukaryotes. The sirtuins are diverse in their cellular functions, and are important to the regulation of oxidative stress, and metabolism. Sirt 1 is localized to the nucleus and possesses deacetylase activity. Sirt 1 has been shown to be able to deacetylate p53, Ku70, NF-kappaB and forkhead proteins to mediate cellular resistance to stress.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-687A maps to a region between residues 25 and 75 of human Sirtuin (Silent Mating Type Information Regulation 2) type 1 using the numbering given in entry NP_036370.2 (GeneID 23411).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-688A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Sirt1 is one of seven members of the sirtuin family of proteins that are homologous to the yeast silent information regulator 2 (Sir2), a NADplus-dependent protein deacetylase that plays a role in lifespan in lower eukaryotes. The sirtuins are diverse in their cellular functions, and are important to the regulation of oxidative stress, and metabolism. Sirt 1 is localized to the nucleus and possesses deacetylase activity. Sirt 1 has been shown to be able to deacetylate p53, Ku70, NF-kappaB and forkhead proteins to mediate cellular resistance to stress.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-688A maps to a region between residue 700 and the C-terminus (residue 747) of human Silent Mating Type Information Regulation 2 homolog 1 using the numbering given in entry NP_036370.2 (GeneID 23411).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-204A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to Sirt1 immobilized on solid support.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A303-811A
related products

WB Erklärungen der Abkürzungen ansehen.
Superoxide dismutase 1 (SOD1) binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. SOD1 is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis [taken from NCBI Entrez Gene (Gene ID: 6647)].

Rabbit IgG SR: human
Immunogen: Synthetic peptide. The epitope recognized by A303-811A maps to a region between residue 54 and 104 of human Superoxide Dismutase 1 using the numbering given in entry NP_000445.1 (GeneID 6647).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-812A
related products

WB Erklärungen der Abkürzungen ansehen.
Superoxide dismutase 1 (SOD1) binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. SOD1 is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis [taken from NCBI Entrez Gene (Gene ID: 6647)].

Rabbit IgG SR: human
Immunogen: Synthetic peptide. The epitope recognized by A303-812A maps to a region between residue 104 and 154 of human Superoxide Dismutase 1 using the numbering given in entry NP_000445.1 (GeneID 6647).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A311-401A
WB Erklärungen der Abkürzungen ansehen.
1 each of A303-811A and A303-812A

Rabbit IgG SR: human
Immunogen: Synthetic peptide. Antibodies were affinity purified using epitopes specific to SOD1 immobilized on solid support.
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A300-358A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
By sequence similarity p300 is related to CBP (CREB-binding protein) and functions as a histone acetyltransferase that can regulate transcription by influencing chromatin organization. P300 has been demonstrated to bind to phosphorylated CREB to mediate cAMP-gene regulation. P300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha). Alternate names for p300 include histone acetyltransferase p300, E1A-associated protein p300, and EP300.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-358A maps to a region between residues 950 and 1000 of human E1A-associated protein p300 using the numbering given in entry NP_001420.2 (GeneID 2033).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-359A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
By sequence similarity p300 is related to CBP (CREB-binding protein) and functions as a histone acetyltransferase that can regulate transcription by influencing chromatin organization. P300 has been demonstrated to bind to phosphorylated CREB to mediate cAMP-gene regulation. P300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha). Alternate names for p300 include histone acetyltransferase p300, E1A-associated protein p300, and EP300.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-359A maps to a region between residues 1000 and 1050 of human E1A-associated protein p300 using the numbering given in entry NP_001420.2 (GeneID 2033).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-097A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to p300 immobilized on solid support.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

IHC-00028
IHC Erklärungen der Abkürzungen ansehen.
By sequence similarity p300 is related to CBP (CREB-binding protein) and functions as a histone acetyltransferase that can regulate transcription by influencing chromatin organization. P300 has been demonstrated to bind to phosphorylated CREB to mediate cAMP-gene regulation. P300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha). Alternate names for p300 include histone acetyltransferase p300, E1A-associated protein p300, and EP300.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00028 maps to a region between residue 950 and 1000 of human 1A-associated protein p300 using the numbering given in entry NP_001420.2 (GeneID 2033).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A302-432A
IP Erklärungen der Abkürzungen ansehen.
Retinoblastoma 1 (Rb1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. Rb1 has also been found to stabilize constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. Alternative names for Rb1 include retinoblastoma susceptibility protein, retinoblastoma-associated protein, pRb, RB, RB1, pp110, and p105-Rb.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A302-432A maps to a region between residue 550 and 600 of human retinoblastoma 1 using the numbering given in entry NP_000312.2 (GeneID 5925).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A302-433A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Retinoblastoma 1 (Rb1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. Rb1 has also been found to stabilize constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. Alternative names for Rb1 include retinoblastoma susceptibility protein, retinoblastoma-associated protein, pRb, RB, RB1, pp110, and p105-Rb.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A302-433A maps to a region between residue 878 and 928 of human retinoblastoma 1 using the numbering given in entry NP_000312.2 (GeneID 5925).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-881A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A302-432A and A302-433A

Rabbit IgG SR: human
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

E88-143
ELISA Erklärungen der Abkürzungen ansehen.
For the detection of Human Lactoferrin in EDTA plasma, urine, and milk. Contains sufficient components to quantitate Human Lactoferrin protein concentration in up to 40 samples, tested in duplicate. Range is 1.56-100 ng/ml.
Bethyl
Icon Datasheet
1 kit

Buy Bulk

551 €

A302-010A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Beta-catenin plays an integral role in the Wnt signaling pathway and is critical to morphogenic signaling and body axis specification. Beta-catenin exists in complexes with cadherins, transmembrane proteins that mediate cell adhesion. When Wnt-signaling proteins bind their receptors, beta-catenin is stabilized and accumulates in the cell. Translocation of stabilized beta-catenin allows its association with transcription factors and the activation of specific gene expression. Alternative names for beta-catenin include catenin beta-1, CTNNB1, and CTNNB.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A302-010A maps to a region between residue 25 and 75 of human beta-catenin using the numbering given in entry NP_001895.1 (GeneID 1499).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A302-011A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Beta-catenin plays an integral role in the Wnt signaling pathway and is critical to morphogenic signaling and body axis specification. Beta-catenin exists in complexes with cadherins, transmembrane proteins that mediate cell adhesion. When Wnt-signaling proteins bind their receptors, beta-catenin is stabilized and accumulates in the cell. Translocation of stabilized beta-catenin allows its association with transcription factors and the activation of specific gene expression. Alternative names for beta-catenin include catenin beta-1, CTNNB1, and CTNNB.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A302-011A maps to a region between residue 710 and 760 of human beta-catenin using the numbering given in entry NP_001895.1 (GeneID 1499).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A302-012A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Beta-catenin plays an integral role in the Wnt signaling pathway and is critical to morphogenic signaling and body axis specification. Beta-catenin exists in complexes with cadherins, transmembrane proteins that mediate cell adhesion. When Wnt-signaling proteins bind their receptors, beta-catenin is stabilized and accumulates in the cell. Translocation of stabilized beta-catenin allows its association with transcription factors and the activation of specific gene expression. Alternative names for beta-catenin include catenin beta-1, CTNNB1, and CTNNB.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A302-012A maps to a region between residue 760 and 781 of human beta-catenin using the numbering given in entry NP_001895.1 (GeneID 1499).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-710A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A302-010A, A302-011A and A302-012A

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

729 €

IHC-00584
IHC Erklärungen der Abkürzungen ansehen.
Involved in the regulation of cell adhesion. The majority of beta-catenin is localized to the cell membrane and is part of E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by IHC-00584 maps to a region between residue 760 and 781 of human beta-catenin using the numbering given in entry NP_001895.1 (GeneID 1499).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A302-065A
related products

WB Erklärungen der Abkürzungen ansehen.
AKT1 is a serine-threonine kinase that functions downstream of PI-3 kinase and is known to phosphorylate several proteins. AKT1 is also known as RAC-PK-alpha, and protein kinase B (PKB). AKT1 mediates the effects of several growth factors such as insulin, IGF-1, EGF, and PDGF to control cell survival and apoptosis. There are numerous substrates of AKT1, some of which are: GSK3-alpha and beta, mTOR, TSC2, Bad, c-Raf, and caspase 9.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A302-065A maps to a region between residue 25 and 75 of human v-akt murine thymoma viral oncogene homolog 1 using the numbering given in entry NP_005154.1 (GeneID 207).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

IHC-00513
IHC Erklärungen der Abkürzungen ansehen.
AKT1 is a serine-threonine kinase that functions downstream of PI-3 kinase and is known to phosphorylate several proteins. AKT1 is also known as RAC-PK-alpha, and protein kinase B (PKB). AKT1 mediates the effects of several growth factors such as insulin, IGF-1, EGF, and PDGF to control cell survival and apoptosis. There are numerous substrates of AKT1, some of which are: GSK3-alpha and beta, mTOR, TSC2, Bad, c-Raf, and caspase 9.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00513 maps to a region between residue 25 and 75 of human v-akt murine thymoma viral oncogene homolog 1 using the numbering given in entry NP_005154.1 (GeneID 207).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A300-140A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Inactivating mutations in NF1 (neurofibromin 1) result in neurofibromatosis type I (NF1) which is characterized by Schwann cell neurofibromas, café-au-lait spots, and benign lesions of the iris. At the cellular level, NF1 functions as a negative regulator of Ras activity. Loss of NF1 leads to increased levels of active Ras-GTP which is important for the formation and maintenance of Schwann cell tumors. Alternate names for NF1 include neurofibromatosis-related protein NF-1, neurofibromin truncated, WSS, NFNS, VRNF, and DKFZp686J1293.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-140A maps to a region between residue 2760 and the C-terminus (residue 2818) of human Neurofibromin 1 using the numbering given in entry NP_000258.1 (GeneID 4763)
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-250A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Polo-like kinase 1 (PLK1) activity is central to the progression through mitosis. PLK1 plays an essential role in spindle formation and chromosome segregation. Recent studies suggest that PLK1 is specifically involved in anaphase spindle elongation, Rho localization to the contractile ring and cytokinesis. Alternate names for PLK1 include PLK-1, polo-like kinase 1, STPK13, and serine-threonine kinase 13.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitopes recognized by A300-250A maps to a region between residues 1 and 50 of human Polo-like kinase 1 using the numbering given in SwissProt entry P53350 (GeneID 5347).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-251A
related products

WB, IP, ICC, IF, PLA Erklärungen der Abkürzungen ansehen.
Polo-like kinase 1 (PLK1) activity is central to the progression through mitosis. PLK1 plays an essential role in spindle formation and chromosome segregation. Recent studies suggest that PLK1 is specifically involved in anaphase spindle elongation, Rho localization to the contractile ring and cytokinesis. Alternate names for PLK1 include PLK-1, polo-like kinase 1, STPK13, and serine-threonine kinase 13.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitopes recognized by A300-251A maps to a region between residues 325 and 375 of human Polo-like kinase using the numbering given in SwissProt entry P53350 (GeneID 5347).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-252A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Polo-like kinase 1 (PLK1) activity is central to the progression through mitosis. PLK1 plays an essential role in spindle formation and chromosome segregation. Recent studies suggest that PLK1 is specifically involved in anaphase spindle elongation, Rho localization to the contractile ring and cytokinesis. Alternate names for PLK1 include PLK-1, polo-like kinase 1, STPK13, and serine-threonine kinase 13.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitopes recognized by A300-252A maps to a region between residue 550 and the C-terminus (residue 603) of human Polo-like kinase using the numbering given in SwissProt entry P53350 (GeneID 5347).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-069A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to PLK1 immobilized on solid support.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

729 €

IHC-00071
ICC Erklärungen der Abkürzungen ansehen.
Polo-like kinase 1 (PLK1) activity is central to the progression through mitosis. PLK1 plays an essential role in spindle formation and chromosome segregation. Recent studies suggest that PLK1 is specifically involved in anaphase spindle elongation, Rho localization to the contractile ring and cytokinesis. Alternate names for PLK1 include PLK-1, polo-like kinase 1, STPK13, and serine-threonine kinase 13.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitopes recognized by IHC-00071 maps to a region between residues 325 and 375 of human Polo-like kinase using the numbering given in SwissProt entry P53350 (GeneID 5347).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

E88-122
ELISA Erklärungen der Abkürzungen ansehen.
1 x 96 well kit. This ELISA is for the detection of human alpha-1 Antitrypsin. It contains sufficient components to quantitate human alpha-1 Antitrypsin in up to 40 samples, tested in duplicate.
Bethyl
Icon Datasheet
manual
1 kit

Buy Bulk

551 €

A300-707A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
p38 MAPK is a member of the MAP (mitogen-activated protein) kinase family that is involved in cellular signaling for a wide variety of activities which includes proliferation, differentiation, and transcriptional regulation. p38 MAPK is responsive to growth factors as well as a variety of cellular stress signals such as UV light, inflammatory cytokines, and osmotic shock. Substrates of P38 MAPK include ATF2, MEF2C, MAX, CDC25B and p53. p38 MAPK is activated by MAP kinase kinases such as MAP2K3, MAP2K6, and MAP2K4. Alternate names for p38 MAPK include p38 Mitogen Activated Protein Kinase, MXI2, MAX-interacting protein 2, CSBP,CSBP1, CSBP2, CSPB1, Csaids (cytokine suppressive anti-inflammatory drug) Binding Protein, SAPK2A, stress-activated protein kinase 2A, p38, p38 Alpha, MAPK14, Mitogen Activated Protein Kinase 14, Exip, PRKM14, PRKM15, RK.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-707A maps to a region between residue 1 and 50 of human Mitogen Activated Protein Kinase 14 (p38 MAPK) using the numbering given in entry NP_001306.1 (GeneID 1432)
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-708A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
p38 MAPK is a member of the MAP (mitogen-activated protein) kinase family that is involved in cellular signaling for a wide variety of activities which includes proliferation, differentiation, and transcriptional regulation. p38 MAPK is responsive to growth factors as well as a variety of cellular stress signals such as UV light, inflammatory cytokines, and osmotic shock. Substrates of P38 MAPK include ATF2, MEF2C, MAX, CDC25B and p53. p38 MAPK is activated by MAP kinase kinases such as MAP2K3, MAP2K6, and MAP2K4. Alternate names for p38 MAPK include p38 Mitogen Activated Protein Kinase, MXI2, MAX-interacting protein 2, CSBP,CSBP1, CSBP2, CSPB1, Csaids (cytokine suppressive anti-inflammatory drug) Binding Protein, SAPK2A, stress-activated protein kinase 2A, p38, p38 Alpha, MAPK14, Mitogen Activated Protein Kinase 14, Exip, PRKM14, PRKM15, RK.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-708A maps to a region between residue 300 and the C-terminus (residue 360) of human Mitogen Activated Protein Kinase 14 (p38 MAPK) using the numbering given in entry NP_001306.1 (GeneID 1432).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-212A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to p38 MAPK immobilized on solid support.

Rabbit IgG SR: human, mouse
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A301-660A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
c-Abl is the human cellular homolog of a the v-Abl viral oncogene. v-Abl was originally discovered as a mouse cell-derived sequence in the genome of the Abelson murine leukemia virus (A-MuLV), a transforming retrovirus isolated by the laboratory of Dr. H.T. Abelson. c-Abl is a tyrosine kinase from the Src-family of tyrosine kinases that localizes to both the cytoplasm and nucleus. It bears an SH2 (src-homology 2) and SH3 (src-homology 3) domain responsible for mediating c-Abl protein-protein interactions. c-Abl is implicated to play a role in multiple cellular processes such as cell cycle checkpoint signaling, apoptosis, cell differentiation, cell adhesion, and transcriptional regulation. Chromosomal translocations involving the c-Abl gene are associated with human leukemias. Alternate names for c-Abl include proto-oncogene tyrosine-protein kinase ABL1, Abelson murine leukemia viral oncogene homolog 1, p150, ABL1, ABL, and JTK7.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-660A maps to a region between residue 550 and 600 of human v-abl Abelson murine leukemia viral oncogene homolog 1 using the numbering given in entry NP_005148.2 (GeneID 25).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-661A
IP Erklärungen der Abkürzungen ansehen.
c-Abl is the human cellular homolog of a the v-Abl viral oncogene. v-Abl was originally discovered as a mouse cell-derived sequence in the genome of the Abelson murine leukemia virus (A-MuLV), a transforming retrovirus isolated by the laboratory of Dr. H.T. Abelson. c-Abl is a tyrosine kinase from the Src-family of tyrosine kinases that localizes to both the cytoplasm and nucleus. It bears an SH2 (src-homology 2) and SH3 (src-homology 3) domain responsible for mediating c-Abl protein-protein interactions. c-Abl is implicated to play a role in multiple cellular processes such as cell cycle checkpoint signaling, apoptosis, cell differentiation, cell adhesion, and transcriptional regulation. Chromosomal translocations involving the c-Abl gene are associated with human leukemias. Alternate names for c-Abl include proto-oncogene tyrosine-protein kinase ABL1, Abelson murine leukemia viral oncogene homolog 1, p150, ABL1, ABL, and JTK7.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-661A maps to a region between residue 850 and 900 of human v-abl Abelson murine leukemia viral oncogene homolog 1 using the numbering given in entry NP_005148.2 (GeneID 25).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-589A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A301-660A and A301-661A

Rabbit IgG SR: human
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

IHC-00405
IHC Erklärungen der Abkürzungen ansehen.
c-Abl is the human cellular homolog of a the v-Abl viral oncogene. v-Abl was originally discovered as a mouse cell-derived sequence in the genome of the Abelson murine leukemia virus (A-MuLV), a transforming retrovirus isolated by the laboratory of Dr. H.T. Abelson. c-Abl is a tyrosine kinase from the Src-family of tyrosine kinases that localizes to both the cytoplasm and nucleus. It bears an SH2 (src-homology 2) and SH3 (src-homology 3) domain responsible for mediating c-Abl protein-protein interactions. c-Abl is implicated to play a role in multiple cellular processes such as cell cycle checkpoint signaling, apoptosis, cell differentiation, cell adhesion, and transcriptional regulation. Chromosomal translocations involving the c-Abl gene are associated with human leukemias. Alternate names for c-Abl include proto-oncogene tyrosine-protein kinase ABL1, Abelson murine leukemia viral oncogene homolog 1, p150, ABL1, ABL, and JTK7.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00405 maps to a region between residue 850 and 900 of human v-abl Abelson murine leukemia viral oncogene homolog 1 using the numbering given in entry NP_005148.2 (GeneID 25).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A301-812A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Cyclin-dependent kinase 2 (CDK2) is a member of the CDK family of protein kinases that regulate cell cycle progression. CDK2 associates with cyclin E or cyclin A to drive the cell cycle through G1- and S-phase. Substrates of CDK2 include pRb, p53, p27, E2F, Brca1, CDK7, B-Myb, PP1 alpha, RNA Pol II CTD, axin, p220 NPAT, ribonucleotide reductase M2, Myo-D, MARCKS, HsCdc6, and CP110. Alternate names for CDK2 include cell division protein kinase 2, and p33 protein kinase.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-812A maps to a region between residue 248 and 298 of human cyclin-dependent kinase 2 using the numbering given in entry NP_001789.2 (GeneID 1017).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

IHC-00374
IHC Erklärungen der Abkürzungen ansehen.
Cyclin-dependent kinase 2 (CDK2) is a member of the CDK family of protein kinases that regulate cell cycle progression. CDK2 associates with cyclin E or cyclin A to drive the cell cycle through G1- and S-phase. Substrates of CDK2 include pRb, p53, p27, E2F, Brca1, CDK7, B-Myb, PP1 alpha, RNA Pol II CTD, axin, p220 NPAT, ribonucleotide reductase M2, Myo-D, MARCKS, HsCdc6, and CP110. Alternate names for CDK2 include cell division protein kinase 2, and p33 protein kinase.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by IHC-00374 maps to a region between residue 248 and 298 of human cyclin-dependent kinase 2 using the numbering given in entry NP_001789.2 (GeneID 1017).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A300-161A
related products

WB, PLA Erklärungen der Abkürzungen ansehen.
Chk1 functions as a checkpoint protein kinase that is critical to the regulation of the Cdc25a and Cdc25c phosphatases that promote S and G2/M phase progression, respectively. Chk1 kinase activity inhibits cell cycle progression in the presence of DNA damage by phosphorylating Cdc25a and Cdc25c and causing the degradation of Cdc25a and cytoplasmic sequestration of Cdc25c. Alternate designations for Chk1 include serine/threonine-protein kinase Chk1, and CHEK1.

Goat IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-161A maps to a region between residues 200 and 250 of human Checkpoint Kinase 1 using the numbering given in entry NP_001265.1 (GeneID 1111).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

386 €

A300-162A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Chk1 functions as a checkpoint protein kinase that is critical to the regulation of the Cdc25a and Cdc25c phosphatases that promote S and G2/M phase progression, respectively. Chk1 kinase activity inhibits cell cycle progression in the presence of DNA damage by phosphorylating Cdc25a and Cdc25c and causing the degradation of Cdc25a and cytoplasmic sequestration of Cdc25c. Alternate designations for Chk1 include serine/threonine-protein kinase Chk1, and CHEK1.

Goat IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-162A maps to a region between residues 250 and 300 of human Checkpoint Kinase 1 using the numbering given in entry NP_001265.1 (GeneID 1111).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

386 €

A300-163A
related products

WB, PLA Erklärungen der Abkürzungen ansehen.
Chk1 functions as a checkpoint protein kinase that is critical to the regulation of the Cdc25a and Cdc25c phosphatases that promote S and G2/M phase progression, respectively. Chk1 kinase activity inhibits cell cycle progression in the presence of DNA damage by phosphorylating Cdc25a and Cdc25c and causing the degradation of Cdc25a and cytoplasmic sequestration of Cdc25c. Alternate designations for Chk1 include serine/threonine-protein kinase Chk1, and CHEK1.

Rabbit IgG SR: human
Immunogen: synthetic phospho-peptide. Immunogen for A300-163A was a phosphorylated synthetic peptide, which represented a portion of human Checkpoint Kinase 1 (GeneID 1111) around serine 317 according to the numbering given in entry NP_001265.1.
Bethyl
Icon Datasheet
100 µl

Buy Bulk

417 €

A300-298A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
Chk1 functions as a checkpoint protein kinase that is critical to the regulation of the Cdc25a and Cdc25c phosphatases that promote S and G2/M phase progression, respectively. Chk1 kinase activity inhibits cell cycle progression in the presence of DNA damage by phosphorylating Cdc25a and Cdc25c and causing the degradation of Cdc25a and cytoplasmic sequestration of Cdc25c. Alternate designations for Chk1 include serine/threonine-protein kinase Chk1, and CHEK1.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-298A maps to a region between residues 250 and 300 of human Checkpoint Kinase 1 using the numbering given in SwissProt entry O14757 (GeneID 1111).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

386 €

A310-044A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to Chk1 immobilized on solid support.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

1103 €

IHC-00004
IHC Erklärungen der Abkürzungen ansehen.
Chk1 functions as a checkpoint protein kinase that is critical to the regulation of the Cdc25a and Cdc25c phosphatases that promote S and G2/M phase progression, respectively. Chk1 kinase activity inhibits cell cycle progression in the presence of DNA damage by phosphorylating Cdc25a and Cdc25c and causing the degradation of Cdc25a and cytoplasmic sequestration of Cdc25c. Alternate designations for Chk1 include serine/threonine-protein kinase Chk1, and CHEK1.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by IHC-00004 maps to a region between residue 250 and 300 of human Checkpoint Kinase 1 using the numbering given in SwissProt entry O14757 (GeneID 1111).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

IHC-00068
IHC, ICC Erklärungen der Abkürzungen ansehen.
Chk1 functions as a checkpoint protein kinase that is critical to the regulation of the Cdc25a and Cdc25c phosphatases that promote S and G2/M phase progression, respectively. Chk1 kinase activity inhibits cell cycle progression in the presence of DNA damage by phosphorylating Cdc25a and Cdc25c and causing the degradation of Cdc25a and cytoplasmic sequestration of Cdc25c. Alternate designations for Chk1 include serine/threonine-protein kinase Chk1, and CHEK1.

Rabbit IgG SR: human
Immunogen: synthetic peptide. Immunogen for IHC-0229P was a phosphorylated synthetic peptide, which represented a portion of human Checkpoint Kinase 1 around serine 317 according to the numbering given in entry NP_001265.1 (GeneID 1111).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

429 €

A80-129
IEP, DD Erklärungen der Abkürzungen ansehen.
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

Goat IgG SR: human
Bethyl
Icon Datasheet
2 ml

Buy Bulk

56 €

A80-129A
related products

ELISA, WB, IHC, ICC Erklärungen der Abkürzungen ansehen.
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

Goat IgG SR: human
Bethyl
Icon Datasheet
1 mg

Buy Bulk

100 €

A80-129AP
related products

ELISA, WB, IHC, ICC Erklärungen der Abkürzungen ansehen.
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

Goat IgG SR: human
Bethyl
Icon Datasheet
1 mg

Buy Bulk

194 €

A80-129B
related products

ELISA, WB Erklärungen der Abkürzungen ansehen.
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

Goat IgG SR: human
Immunogen: Human Albumin
Bethyl
Icon Datasheet
1 mg

Buy Bulk

154 €

A80-129F
ICC, IHC Erklärungen der Abkürzungen ansehen.
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

Goat IgG SR: human
Bethyl
Icon Datasheet
1 mg

Buy Bulk

127 €

A80-129P
related products

ELISA, WB, IHC, ICC Erklärungen der Abkürzungen ansehen.
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

Goat IgG SR: human
Bethyl
Icon Datasheet
1 mg

Buy Bulk

160 €

A80-229A
related products

ELISA, WB, IHC, ICC Erklärungen der Abkürzungen ansehen.
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

Goat IgG SR: human
Bethyl
Icon Datasheet
500 µg

Buy Bulk

100 €

A80-229AP
related products

ELISA, WB, IHC, ICC Erklärungen der Abkürzungen ansehen.
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

Goat IgG SR: human
Bethyl
Icon Datasheet
500 µg

Buy Bulk

174 €

A80-229F
ICC, IHC Erklärungen der Abkürzungen ansehen.
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

Goat IgG SR: human
Bethyl
Icon Datasheet
500 µg

Buy Bulk

127 €

A80-229P
related products

ELISA, WB, IHC, ICC Erklärungen der Abkürzungen ansehen.
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

Goat IgG SR: human
Bethyl
Icon Datasheet
500 µg

Buy Bulk

160 €

E80-129
related products

ELISA Erklärungen der Abkürzungen ansehen.
Antibodies, calibrators and conjugate are packaged to provide a quantitative ELISA kit containing reagents sufficient for 1000 single well assays. Kits do not include plates, buffers or substrate. If needed order ELISA Accessory Kit # E101.
Bethyl
Icon Datasheet
1000 wells

Buy Bulk

401 €

E88-129
ELISA Erklärungen der Abkürzungen ansehen.
Sandwich ELISA. Complete kit for quantitating human Albumin in in serum, plasma, cerebrospinal fluid, milk, and urine. For up to 40 samples tested in duplicate.
Bethyl
Icon Datasheet
1 kit

Buy Bulk

551 €

A301-692A
IP Erklärungen der Abkürzungen ansehen.
Focal adhesion kinase (FAK) is a non-receptor protein-tyrosine kinase that localizes to the cytoplasm and is concentrated in focal adhesions, macromolecular assemblies that form a communicative link between the cell and the extracellular matrix. FAK signaling is stimulated by integrin-mediated responses, as well as growth factors, chemokines, and G-protein-linked receptors. FAK signaling influences cell motility, invasion, and survival. Alternate names for FAK include FADK1, pp125FAK, protein-tyrosine kinase 2, PTK2 protein tyrosine kinase 2, PTK2, and FAK1.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-692A maps to a region between residue 325 and 375 of human focal adhesion kinase 1 using the numbering given in entry NP_005598.3 (GeneID 5747).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-693A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Focal adhesion kinase (FAK) is a non-receptor protein-tyrosine kinase that localizes to the cytoplasm and is concentrated in focal adhesions, macromolecular assemblies that form a communicative link between the cell and the extracellular matrix. FAK signaling is stimulated by integrin-mediated responses, as well as growth factors, chemokines, and G-protein-linked receptors. FAK signaling influences cell motility, invasion, and survival. Alternate names for FAK include FADK1, pp125FAK, protein-tyrosine kinase 2, PTK2 protein tyrosine kinase 2, PTK2, and FAK1.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-693A maps to a region between residue 1002 and 1052 of human focal adhesion kinase 1 using the numbering given in entry NP_005598.3 (GeneID 5747).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-600A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A301-692A and A301-693A

Rabbit IgG SR: human
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A301-544A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
PTPN11/Shp2 is a src-homology 2-containing protein-tyrosine phosphatase (PTP). PTPN11/Shp2 is a non-receptor phosphatase that mediates a variety of cytokine, growth factor, and hormone signals. Signal transduction by PTPN11/Shp2 is achieved via the activation of the Ras/mitogen-activated protein kinase pathway. Heterogenous gain of function mutations in PTPN11/Shp2 are associated with juvenile myelomonocytic leukemia (JMML) and Noonan syndrome, a disorder characterized by short stature, facial dysmorphology, and congenital heart defects. Alternate names for PTPN11/Shp2 include tyrosine-protein phosphatase non-receptor type 11, protein-tyrosine phosphatase 2C, PTP-2C, PTP2C, PTP-1D, CFC, NS1, SH-PTP3 and SH-PTP2.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A301-544A maps to a region between residue 543 and 593 of human tyrosine-protein phosphatase non-receptor type 11 using the numbering given in entry NP_002825.3 (GeneID 5781).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-460A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
TNF receptor-associated factor 2 (TRAF2) regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. TRAF2 is required for normal antibody isotype switching from IgM to IgG. TRAF2 has E3 ubiquitin-protein ligase activity and promotes 'Lys-63'-linked ubiquitination of target proteins, such as BIRC3, RIPK1 and TICAM1. TRAF2 is an essential constituent of several E3 ubiquitin-protein ligase complexes, where it promotes the ubiquitination of target proteins by bringing them into contact with other E3 ubiquitin ligases. Alternative names for TRAF2 include E3 ubiquitin-protein ligase TRAF2, tumor necrosis factor type 2 receptor-associated protein 3, and TRAP3. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q12933]

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A303-460A maps to a region between residue 175 and 225 of human TNF receptor-associated factor 2 using the numbering given in entry NP_066961.2 (GeneID 7186).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-461A
IP Erklärungen der Abkürzungen ansehen.
TNF receptor-associated factor 2 (TRAF2) regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. TRAF2 is required for normal antibody isotype switching from IgM to IgG. TRAF2 has E3 ubiquitin-protein ligase activity and promotes 'Lys-63'-linked ubiquitination of target proteins, such as BIRC3, RIPK1 and TICAM1. TRAF2 is an essential constituent of several E3 ubiquitin-protein ligase complexes, where it promotes the ubiquitination of target proteins by bringing them into contact with other E3 ubiquitin ligases. Alternative names for TRAF2 include E3 ubiquitin-protein ligase TRAF2, tumor necrosis factor type 2 receptor-associated protein 3, and TRAP3. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q12933]

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A303-461A maps to a region between residue 300 and 350 of human TNF receptor-associated factor 2 using the numbering given in entry NP_066961.2 (GeneID 7186).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A311-276A
WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A303-460A and A303-461A

Rabbit IgG SR: human
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A302-061A
related products

WB Erklärungen der Abkürzungen ansehen.
Extracellular signal-regulated kinase 2 (ERK2/p42) is also known as mitogen-activated protein kinase 1 (MAPK1). ERK2 is part of a signal transduction pathway that begins with the small GTPase Ras and continues through a cascade of protein kinases that include Raf and MEK. Activation of this signaling pathway influences many cellular processes such as proliferation, differentiation and survival. ERK2 is very similar in sequence to ERK1/p44 and the activities of both ERK1 and ERK2 are usually considered together as total ERK activity. More recent evidence has shown that ERK1 and ERK2 are not functionally redundant and may have very different and specific roles. Alternative names for ERK2 include p42-MAPK, ERT1, MAPK2, PRKM1, and PRKM2.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A302-061A maps to a region between residue 310 and 360 of human extracellular signal-regulated kinase-2 (mitogen-activated protein kinase 1) using the numbering given in entry NP_002736.3 (GeneID 5594).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

IHC-00506
IHC Erklärungen der Abkürzungen ansehen.
Extracellular signal-regulated kinase 2 (ERK2/p42) is also known as mitogen-activated protein kinase 1 (MAPK1). ERK2 is part of a signal transduction pathway that begins with the small GTPase Ras and continues through a cascade of protein kinases that include Raf and MEK. Activation of this signaling pathway influences many cellular processes such as proliferation, differentiation and survival. ERK2 is very similar in sequence to ERK1/p44 and the activities of both ERK1 and ERK2 are usually considered together as total ERK activity. More recent evidence has shown that ERK1 and ERK2 are not functionally redundant and may have very different and specific roles. Alternative names for ERK2 include p42-MAPK, ERT1, MAPK2, PRKM1, and PRKM2.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00506 maps to a region between residue 310 and 360 of human extracellular signal-regulated kinase-2 (mitogen-activated protein kinase 1) using the numbering given in entry NP_002736.3 (GeneID 5594).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A303-492A
IP Erklärungen der Abkürzungen ansehen.
Cyclin-dependent kinase 9 (CDK9) is a member of the CDK family of kinases and a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. CDK9 forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. Alternative names for CDK9 include cell division cycle2-like protein kinase 4, cell division protein kinase 9, serine/threonine-protein kinase PITALRE, tat-associated kinase complex catalytic subunit, CDC2L4, and TAK.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A303-492A maps to a region between residue 1 and 50 of human Cyclin-Dependent Kinase 9 using the numbering given in entry NP_001252.1 (GeneID 1025).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-493A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Cyclin-dependent kinase 9 (CDK9) is a member of the CDK family of kinases and a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. CDK9 forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. Alternative names for CDK9 include cell division cycle2-like protein kinase 4, cell division protein kinase 9, serine/threonine-protein kinase PITALRE, tat-associated kinase complex catalytic subunit, CDC2L4, and TAK.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A303-493A maps to a region between residue 322 and 372 of human Cyclin-Dependent Kinase 9 using the numbering given in entry NP_001252.1 (GeneID 1025).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A311-289A
WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A303-492A and A303-493A

Rabbit SR: human
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A300-005A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
BRCA2 was identified as a gene with germline mutations that predisposes women to breast cancer. An important function of BRCA2 involves its direct interaction with RAD51 and the process of homologous recombination in DNA double strand break repair. BRCA2 and BRCA1 primary sequences are not similar, however the proteins exhibit similar patterns of expression and sub-cellular localization. Although the phenotype of disruptions of BRCA2 is similar to BRCA1, BRCA2 appears to possess functions distinct from BRCA1. BRCA2 is also known as breast cancer type 2 susceptibility protein, Fanconi anemia group D1 protein, FAC, FACD, FAD1, FANCD1, FANCB, and BRCC2 .

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-005A maps to a region between residue 3350 and the C-terminus (residue 3418) of human Breast Cancer Gene 2 using the numbering given in entry NP_000050.1 (GeneID 675).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-434A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
BRCA2 was identified as a gene with germline mutations that predisposes women to breast cancer. An important function of BRCA2 involves its direct interaction with RAD51 and the process of homologous recombination in DNA double strand break repair. BRCA2 and BRCA1 primary sequences are not similar, however the proteins exhibit similar patterns of expression and sub-cellular localization. Although the phenotype of disruptions of BRCA2 is similar to BRCA1, BRCA2 appears to possess functions distinct from BRCA1. BRCA2 is also known as breast cancer type 2 susceptibility protein, Fanconi anemia group D1 protein, FAC, FACD, FAD1, FANCD1, FANCB, and BRCC2 .

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A303-434A maps to a region between residue 450 and 500 of human Breast Cancer 2, Early Onset using the numbering given in entry NP_000050.1 (GeneID 675).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-435A
IP Erklärungen der Abkürzungen ansehen.
BRCA2 was identified as a gene with germline mutations that predisposes women to breast cancer. An important function of BRCA2 involves its direct interaction with RAD51 and the process of homologous recombination in DNA double strand break repair. BRCA2 and BRCA1 primary sequences are not similar, however the proteins exhibit similar patterns of expression and sub-cellular localization. Although the phenotype of disruptions of BRCA2 is similar to BRCA1, BRCA2 appears to possess functions distinct from BRCA1. BRCA2 is also known as breast cancer type 2 susceptibility protein, Fanconi anemia group D1 protein, FAC, FACD, FAD1, FANCD1, FANCB, and BRCC2 .

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A303-435A maps to a region between residue 2850 and 2900 of human Breast Cancer 2, Early Onset using the numbering given in entry NP_000050.1 (GeneID 675).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A311-267A
WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A303-434A and A303-435A

Rabbit IgG SR: human
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

S300-005
IP Erklärungen der Abkürzungen ansehen.
Rabbit anti-human BRCA2 affinity purified Antibodies were coupled to agarose beads using a cyanogen bromide method.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
100 µg

Buy Bulk

367 €

A300-105A
related products

WB, IP, IF, ChIP, IHC Erklärungen der Abkürzungen ansehen.
Menin is the gene product of the putative tumor suppressor MEN1 associated with the syndrome termed multiple endocrine neoplasia type 1 that may function in the regulation of DNA synthesis or the response to DNA damage. Menin has been shown to interact with JunD, a member of the AP-1 heterodimer and inhibit transcription. Menin has also been shown to interact with Pem, FANCD2, RPA, NMMHCII-A, GFAP, vimentin, Hsp70, NfkappaB proteins, Smads, mSin3A and is part of the MLL2 and MLL1 Set1-like histone H3 K4 methyltransferase complex where it interacts directly with ASH2, Rbbp5, and WDR5. As part of the MLL complexes, menin may mediate its tumor suppressor activity via the regulation of histone methylation of HOX and CDK inhibitor genes. Alternate names for Menin are MEAI, multiple endocrine adenomatosis 1, suppressor Candidate Gene 2, and SCG2.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-105A maps to a region between residue 575 and the C-terminus (residue 615) of human Multiple Endocrine Neoplasia 1 using the numbering given in entry NP_000235.2 (GeneID 4221).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-106A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
Menin is the gene product of the putative tumor suppressor MEN1 associated with the syndrome termed multiple endocrine neoplasia type 1 that may function in the regulation of DNA synthesis or the response to DNA damage. Menin has been shown to interact with JunD, a member of the AP-1 heterodimer and inhibit transcription. Menin has also been shown to interact with Pem, FANCD2, RPA, NMMHCII-A, GFAP, vimentin, Hsp70, NfkappaB proteins, Smads, mSin3A and is part of the MLL2 and MLL1 Set1-like histone H3 K4 methyltransferase complex where it interacts directly with ASH2, Rbbp5, and WDR5. As part of the MLL complexes, menin may mediate its tumor suppressor activity via the regulation of histone methylation of HOX and CDK inhibitor genes. Alternate names for Menin are MEAI, multiple endocrine adenomatosis 1, suppressor Candidate Gene 2, and SCG2.

Goat IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-106A maps to a region between residue 575 and the C-terminus (residue 615) of human Multiple Endocrine Neoplasia 1 using the numbering given in entry NP_000235.2 (GeneID 4221).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-106B
related products

WB, IP, IHC Erklärungen der Abkürzungen ansehen.
Menin is the gene product of the putative tumor suppressor MEN1 associated with the syndrome termed multiple endocrine neoplasia type 1 that may function in the regulation of DNA synthesis or the response to DNA damage. Menin has been shown to interact with JunD, a member of the AP-1 heterodimer and inhibit transcription. Menin has also been shown to interact with Pem, FANCD2, RPA, NMMHCII-A, GFAP, vimentin, Hsp70, NfkappaB proteins, Smads, mSin3A and is part of the MLL2 and MLL1 Set1-like histone H3 K4 methyltransferase complex where it interacts directly with ASH2, Rbbp5, and WDR5. As part of the MLL complexes, menin may mediate its tumor suppressor activity via the regulation of histone methylation of HOX and CDK inhibitor genes. Alternate names for Menin are MEAI, multiple endocrine adenomatosis 1, suppressor Candidate Gene 2, and SCG2.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-106B maps to a region between residue 575 and the C-terminus (residue 615) of human Multiple Endocrine Neoplasia 1 using the numbering given in entry NP_000235.2 (GeneID 4221).
Bethyl
Icon Datasheet
100 µg

Buy Bulk

374 €

A300-114A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Menin is the gene product of the putative tumor suppressor MEN1 associated with the syndrome termed multiple endocrine neoplasia type 1 that may function in the regulation of DNA synthesis or the response to DNA damage. Menin has been shown to interact with JunD, a member of the AP-1 heterodimer and inhibit transcription. Menin has also been shown to interact with Pem, FANCD2, RPA, NMMHCII-A, GFAP, vimentin, Hsp70, NfkappaB proteins, Smads, mSin3A and is part of the MLL2 and MLL1 Set1-like histone H3 K4 methyltransferase complex where it interacts directly with ASH2, Rbbp5, and WDR5. As part of the MLL complexes, menin may mediate its tumor suppressor activity via the regulation of histone methylation of HOX and CDK inhibitor genes. Alternate names for Menin are MEAI, multiple endocrine adenomatosis 1, suppressor Candidate Gene 2, and SCG2.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-114A maps to a region between residue 275 and 325 of human Multiple Endocrine Neoplasia 1 using the numbering given in entry NP_000235.2 (GeneID 4221).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-115A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Menin is the gene product of the putative tumor suppressor MEN1 associated with the syndrome termed multiple endocrine neoplasia type 1 that may function in the regulation of DNA synthesis or the response to DNA damage. Menin has been shown to interact with JunD, a member of the AP-1 heterodimer and inhibit transcription. Menin has also been shown to interact with Pem, FANCD2, RPA, NMMHCII-A, GFAP, vimentin, Hsp70, NfkappaB proteins, Smads, mSin3A and is part of the MLL2 and MLL1 Set1-like histone H3 K4 methyltransferase complex where it interacts directly with ASH2, Rbbp5, and WDR5. As part of the MLL complexes, menin may mediate its tumor suppressor activity via the regulation of histone methylation of HOX and CDK inhibitor genes. Alternate names for Menin are MEAI, multiple endocrine adenomatosis 1, suppressor Candidate Gene 2, and SCG2.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-115A maps to a region between residue 500 and 550 of human Multiple Endocrine Neoplasia 1 using the numbering given in entry NP_000235.2 (GeneID 4221).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-027A
related products

WB, IP, IF, IHC, ChIP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to Menin immobilized on solid support.

Rabbit, Goat IgG SR: human, mouse
Bethyl
Icon Datasheet
1 pack

Buy Bulk

966 €

A500-003A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Menin is the gene product of the putative tumor suppressor MEN1 associated with the syndrome termed multiple endocrine neoplasia type 1 that may function in the regulation of DNA synthesis or the response to DNA damage. Menin has been shown to interact with JunD, a member of the AP-1 heterodimer and inhibit transcription. Menin has also been shown to interact with Pem, FANCD2, RPA, NMMHCII-A, GFAP, vimentin, Hsp70, NfkappaB proteins, Smads, mSin3A and is part of the MLL2 and MLL1 Set1-like histone H3 K4 methyltransferase complex where it interacts directly with ASH2, Rbbp5, and WDR5. As part of the MLL complexes, menin may mediate its tumor suppressor activity via the regulation of histone methylation of HOX and CDK inhibitor genes. Alternate names for Menin are MEAI, multiple endocrine adenomatosis 1, suppressor Candidate Gene 2, and SCG2.

Mouse IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A500-003A maps to a region between residue 575 and the C-terminus (residue 615) of human Multiple Endocrine Neoplasia 1 using the numbering given in entry NP_000235.2 (GeneID 4221).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

IHC-00572
IHC Erklärungen der Abkürzungen ansehen.
May be involved in DNA repair.

Rabbit SR: Human, Mouse
Immunogen: synthetic peptide. The epitope recognized by IHC-00572 maps to a region between residue 575 and the C-terminus (residue 615) of human Multiple Endocrine Neoplasia 1 using the numbering given in entry NP_000235.2 (GeneID 4221).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

IHC-00575
IHC Erklärungen der Abkürzungen ansehen.
May be involved in DNA repair.

Mouse IgG1 kappa SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00575 maps to a region between residue 575 and the C-terminus (residue 615) of human Multiple Endocrine Neoplasia 1 using the numbering given in entry NP_000235.2 (GeneID 4221).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

399 €

S300-105
IP Erklärungen der Abkürzungen ansehen.
Rabbit anti-human Menin affinity purified Antibodies were coupled to agarose beads using a cyanogen bromide method.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
100 µg

Buy Bulk

367 €

A302-402A
related products

WB Erklärungen der Abkürzungen ansehen.
Nucleophosmin (NPM1) is involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors TP53/p53 and ARF. It associates with nucleolar ribonucleoprotein structures and binds single-stranded nucleic acids. NPM1 binds ribosomes presumably to drive ribosome nuclear export. Chromosomal aberrations involving NPM1 have been identified in several types of leukemia. Alternative names for NPM1 include nucleolar phosphoprotein B23, Numatrin, nucleolar protein NO38, and NPM.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A302-402A maps to a region between residue 100 and 150 of human nucleophosmin using the numbering given in entry NP_002511.1 (GeneID 4869).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A302-403A
IP Erklärungen der Abkürzungen ansehen.
Nucleophosmin (NPM1) is involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors TP53/p53 and ARF. It associates with nucleolar ribonucleoprotein structures and binds single-stranded nucleic acids. NPM1 binds ribosomes presumably to drive ribosome nuclear export. Chromosomal aberrations involving NPM1 have been identified in several types of leukemia. Alternative names for NPM1 include nucleolar phosphoprotein B23, Numatrin, nucleolar protein NO38, and NPM.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A302-403A maps to a region between residue 200 and 250 of human nucleophosmin using the numbering given in entry NP_002511.1 (GeneID 4869).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A302-404A
IP Erklärungen der Abkürzungen ansehen.
Nucleophosmin (NPM1) is involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors TP53/p53 and ARF. It associates with nucleolar ribonucleoprotein structures and binds single-stranded nucleic acids. NPM1 binds ribosomes presumably to drive ribosome nuclear export. Chromosomal aberrations involving NPM1 have been identified in several types of leukemia. Alternative names for NPM1 include nucleolar phosphoprotein B23, Numatrin, nucleolar protein NO38, and NPM.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A302-404A maps to a region between residue 250 and 294 of human nucleophosmin using the numbering given in entry NP_002511.1 (GeneID 4869).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-870A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A302-402A, A302-403A and A302-404A

Rabbit IgG SR: human
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

729 €

A300-024A
related products

WB Erklärungen der Abkürzungen ansehen.
PTEN (phosphatase and tensin homolog) is a phosphatidylinositol-3,4,5-triphosphate 3-phosphatase that has been identified as a tumor suppressor. PTEN is a dual specificity tyrosine and serine/threonine phosphatase that preferentially dephosphorylates phosphoinositide substrates and negatively regulates the AKT/PKB signaling pathway. Through its action, PTEN has been shown to modulate cell cycle progression, cell survival, cell migration, cell adhesion, and insulin signaling. PTEN is also known as mutated in multiple advanced cancers 1, MMAC1, TEP1, BZS, MHAM, and MGC11227.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-024A maps to a region between residue 350 and the C-terminus (residue 403) of human phosphatase and tensin homolog using the numbering given in entry NP_000305.2 (GeneID 5728).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-699A
IP Erklärungen der Abkürzungen ansehen.
PTEN (phosphatase and tensin homolog) is a phosphatidylinositol-3,4,5-triphosphate 3-phosphatase that has been identified as a tumor suppressor. PTEN is a dual specificity tyrosine and serine/threonine phosphatase that preferentially dephosphorylates phosphoinositide substrates and negatively regulates the AKT/PKB signaling pathway. Through its action, PTEN has been shown to modulate cell cycle progression, cell survival, cell migration, cell adhesion, and insulin signaling. PTEN is also known as mutated in multiple advanced cancers 1, MMAC1, TEP1, BZS, MHAM, and MGC11227.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-699A maps to a region between residue 1 and 50 of human phosphatase and tensin homolog using the numbering given in entry NP_000305.2 (GeneID 5728).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

417 €

A300-700A
IP Erklärungen der Abkürzungen ansehen.
PTEN (phosphatase and tensin homolog) is a phosphatidylinositol-3,4,5-triphosphate 3-phosphatase that has been identified as a tumor suppressor. PTEN is a dual specificity tyrosine and serine/threonine phosphatase that preferentially dephosphorylates phosphoinositide substrates and negatively regulates the AKT/PKB signaling pathway. Through its action, PTEN has been shown to modulate cell cycle progression, cell survival, cell migration, cell adhesion, and insulin signaling. PTEN is also known as mutated in multiple advanced cancers 1, MMAC1, TEP1, BZS, MHAM, and MGC11227.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-700A maps to a region between residue 325 and 375 of human phosphatase and tensin homolog using the numbering given in entry NP_000305.2 (GeneID 5728).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

417 €

A300-701A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
PTEN (phosphatase and tensin homolog) is a phosphatidylinositol-3,4,5-triphosphate 3-phosphatase that has been identified as a tumor suppressor. PTEN is a dual specificity tyrosine and serine/threonine phosphatase that preferentially dephosphorylates phosphoinositide substrates and negatively regulates the AKT/PKB signaling pathway. Through its action, PTEN has been shown to modulate cell cycle progression, cell survival, cell migration, cell adhesion, and insulin signaling. PTEN is also known as mutated in multiple advanced cancers 1, MMAC1, TEP1, BZS, MHAM, and MGC11227.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-701A maps to a region between residue 350 and the C-terminus (residue 403) of human phosphatase and tensin homolog using the numbering given in entry NP_000305.2 (GeneID 5728).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

417 €

A310-209A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to PTEN immobilized on solid support.

Rabbit IgG SR: human, mouse
Bethyl
Icon Datasheet
1 pack

Buy Bulk

873 €

IHC-00358
IHC Erklärungen der Abkürzungen ansehen.
PTEN (phosphatase and tensin homolog) is a phosphatidylinositol-3,4,5-triphosphate 3-phosphatase that has been identified as a tumor suppressor. PTEN is a dual specificity tyrosine and serine/threonine phosphatase that preferentially dephosphorylates phosphoinositide substrates and negatively regulates the AKT/PKB signaling pathway. Through its action, PTEN has been shown to modulate cell cycle progression, cell survival, cell migration, cell adhesion, and insulin signaling. PTEN is also known as mutated in multiple advanced cancers 1, MMAC1, TEP1, BZS, MHAM, and MGC11227.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00358 maps to a region between residue 350 and the C-terminus (residue 403) of human phosphatase and tensin homolog using the numbering given in entry NP_000305.2 (GeneID 5728).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A300-516A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
DNA-PKcs is the catalytic subunit of a DNA-dependent serine-threonine protein kinase (DNA-PK). DNA-PK is a heterotrimer comprised of DNA-PKcs and the Ku709/Ku86 dimer. DNA-PK is involved in DNA damage repair and V(D)J recombination. DNA-PK phosphorylates Artemis, a protein required for nonhomologous end-joining and is necessary for the loading of Artemis on damaged DNA. Alternate names for DNA-PKcs include DNA-dependent protein kinase catalytic subunit, DNA-PK catalytic subunit, DNPK1, p460, PRKDC, HYRC, HYRC1, and XRCC7.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-516A maps to a region between residues 1850 and 1900 of human DNA-Dependent Protein Kinase, catalytic subunit using the numbering given in entry NP_008835.5 (GeneID 5591).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-517A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
DNA-PKcs is the catalytic subunit of a DNA-dependent serine-threonine protein kinase (DNA-PK). DNA-PK is a heterotrimer comprised of DNA-PKcs and the Ku709/Ku86 dimer. DNA-PK is involved in DNA damage repair and V(D)J recombination. DNA-PK phosphorylates Artemis, a protein required for nonhomologous end-joining and is necessary for the loading of Artemis on damaged DNA. Alternate names for DNA-PKcs include DNA-dependent protein kinase catalytic subunit, DNA-PK catalytic subunit, DNPK1, p460, PRKDC, HYRC, HYRC1, and XRCC7.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-517A maps to a region between residues 2050 and 2100 of human DNA-Dependent Protein Kinase, catalytic subunit using the numbering given in entry NP_008835.5 (GeneID 5591).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-518A
related products

WB Erklärungen der Abkürzungen ansehen.
DNA-PKcs is the catalytic subunit of a DNA-dependent serine-threonine protein kinase (DNA-PK). DNA-PK is a heterotrimer comprised of DNA-PKcs and the Ku709/Ku86 dimer. DNA-PK is involved in DNA damage repair and V(D)J recombination. DNA-PK phosphorylates Artemis, a protein required for nonhomologous end-joining and is necessary for the loading of Artemis on damaged DNA. Alternate names for DNA-PKcs include DNA-dependent protein kinase catalytic subunit, DNA-PK catalytic subunit, DNPK1, p460, PRKDC, HYRC, HYRC1, and XRCC7.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-518A maps to a region between residues 2100 and 2150 of human DNA-Dependent Protein Kinase, catalytic subunit using the numbering given in entry NP_008835.5 (GeneID 5591).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-519A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
DNA-PKcs is the catalytic subunit of a DNA-dependent serine-threonine protein kinase (DNA-PK). DNA-PK is a heterotrimer comprised of DNA-PKcs and the Ku709/Ku86 dimer. DNA-PK is involved in DNA damage repair and V(D)J recombination. DNA-PK phosphorylates Artemis, a protein required for nonhomologous end-joining and is necessary for the loading of Artemis on damaged DNA. Alternate names for DNA-PKcs include DNA-dependent protein kinase catalytic subunit, DNA-PK catalytic subunit, DNPK1, p460, PRKDC, HYRC, HYRC1, and XRCC7.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-519A maps to a region between residue 4075 and the C-terminus (residue 4128) of human DNA-Dependent Protein Kinase, catalytic subunit using the numbering given in entry NP_008835.5 (GeneID 5591).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-967A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
DNA-PKcs is the catalytic subunit of a DNA-dependent serine-threonine protein kinase (DNA-PK). DNA-PK is a heterotrimer comprised of DNA-PKcs and the Ku709/Ku86 dimer. DNA-PK is involved in DNA damage repair and V(D)J recombination. DNA-PK phosphorylates Artemis, a protein required for nonhomologous end-joining and is necessary for the loading of Artemis on damaged DNA.

Goat IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A303-967A maps to a region between residue 4078 to 4128 of human Protein Kinase, DNA-Activated, Catalytic Polypeptide using the numbering given in entry NP_008835.5 (GeneID 5591).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-147A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to DNA-PKcs immobilized on solid support.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

966 €

IHC-00044
IHC Erklärungen der Abkürzungen ansehen.
DNA-PKcs is the catalytic subunit of a DNA-dependent serine-threonine protein kinase (DNA-PK). DNA-PK is a heterotrimer comprised of DNA-PKcs and the Ku709/Ku86 dimer. DNA-PK is involved in DNA damage repair and V(D)J recombination. DNA-PK phosphorylates Artemis, a protein required for nonhomologous end-joining and is necessary for the loading of Artemis on damaged DNA. Alternate names for DNA-PKcs include DNA-dependent protein kinase catalytic subunit, DNA-PK catalytic subunit, DNPK1, p460, PRKDC, HYRC, HYRC1, and XRCC7.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00044 maps to a region between residue 2100 and 2150 of human DNA-Dependent Protein Kinase, catalytic subunit using the numbering given in entry NP_008835.5 (GeneID 5591).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A300-712A
IP Erklärungen der Abkürzungen ansehen.
Histone deacetylase 1 (HDAC1) is a class I histone deacetylase that catalyzes the removal of the acetyl group on lysine residues of the N-terminus of the core histones H2A, H2B, H3, and H4. HDAC1 is a component of multiple deacetylating complexes such as Sin3, NuRD, and CoRest that function to repress gene transcription. Alternate names for HDAC1 include RPD3L1, HD1, GON-10, and DKFZp686H12203.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-712A maps to the N-terminus of human Histone Deacetylase 1 using the numbering given in entry NP_004955.2 (GeneID 3065).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-713A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
Histone deacetylase 1 (HDAC1) is a class I histone deacetylase that catalyzes the removal of the acetyl group on lysine residues of the N-terminus of the core histones H2A, H2B, H3, and H4. HDAC1 is a component of multiple deacetylating complexes such as Sin3, NuRD, and CoRest that function to repress gene transcription. Alternate names for HDAC1 include RPD3L1, HD1, GON-10, and DKFZp686H12203.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-713A maps to region between residue 425 and the C-terminus (residue 482) of human Histone Deacetylase 1 using the numbering given in entry NP_004955.2 (GeneID 3065).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-214A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to HDAC1 immobilized on solid support.

Rabbit IgG SR: human, mouse
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

IHC-00056
IHC Erklärungen der Abkürzungen ansehen.
Histone deacetylase 1 (HDAC1) is a class I histone deacetylase that catalyzes the removal of the acetyl group on lysine residues of the N-terminus of the core histones H2A, H2B, H3, and H4. HDAC1 is a component of multiple deacetylating complexes such as Sin3, NuRD, and CoRest that function to repress gene transcription. Alternate names for HDAC1 include RPD3L1, HD1, GON-10, and DKFZp686H12203.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by IHC-00056 maps to a region between residue 425 and the C-terminus (residue 482) of human Histone Deacetylase 1 using the numbering given in entry NP_004955.2 (GeneID 3065).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A303-490A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
The glucocorticoid receptor (GR) functions as both a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Alternative names for the Glucocorticoid receptor include GR, GRL, NR3C1, and nuclear receptor subfamily 3 group C, member 1. [taken from NCBI Entrez Gene (Gene ID: 2908)]

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A303-490A maps to a region between residue 1 and 50 of human Glucocorticoid Receptor using the numbering given in entry NP_000167.1 (GeneID 2908).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-491A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
The glucocorticoid receptor (GR) functions as both a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Alternative names for the Glucocorticoid receptor include GR, GRL, NR3C1, and nuclear receptor subfamily 3 group C, member 1. [taken from NCBI Entrez Gene (Gene ID: 2908)]

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A303-491A maps to a region between residue 150 and 200 of human Glucocorticoid Receptor using the numbering given in entry NP_000167.1 (GeneID 2908).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A311-288A
WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A303-490A and A303-491A

Rabbit SR: human
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A302-855A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human, mouse
Immunogen: Synthetic peptide. The epitope recognized by A302-855A maps to a region between residue 325 and 375 of human Sequestosome-1 using the numbering given in entry NP_003891.1 (GeneID 8878).
Bethyl
Icon Datasheet
100 µg

Buy Bulk

349 €

A302-856A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide. The epitope recognized by A302-856A maps to a region between residue 375 and 425 of human Sequestosome-1 using the numbering given in entry NP_003891.1 (GeneID 8878).
Bethyl
Icon Datasheet
100 µg

Buy Bulk

349 €

A302-857A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human, mouse
Immunogen: Synthetic peptide. The epitope recognized by A302-857A maps to a region between residue 425 and 440 of human Sequestosome-1 using the numbering given in entry NP_003891.1 (GeneID 8878).
Bethyl
Icon Datasheet
20 µg

Buy Bulk

349 €

A311-053A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human, mouse
Bethyl
Icon Datasheet
1 Stck

Buy Bulk

729 €

A300-618A
IP, PLA Erklärungen der Abkürzungen ansehen.
Chk2 functions as a checkpoint protein kinase in response to DNA damage to maintain genomic stability. The yeast homologs are Rad53 and Cds1. The two major upstream controllers of Chk2 are ATM and ATR which are part of the phosphatidylinositol 3-kinase family. When activated, Chk2 targets p53, BRCA1, Cdc25A and Cdc25C to cause cell cycle arrest. Chk2 is also known as serine/threonine-protein kinase CHK2, CHEK2, CDS1, LFS2, Rad53, HuCds1, and PP1425.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-618A maps to a region between residues 1 and 50 of human Checkpoint Kinase 2 using the numbering given in entry NP_009125.1 (GeneID 11200).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-619A
IP Erklärungen der Abkürzungen ansehen.
Chk2 functions as a checkpoint protein kinase in response to DNA damage to maintain genomic stability. The yeast homologs are Rad53 and Cds1. The two major upstream controllers of Chk2 are ATM and ATR which are part of the phosphatidylinositol 3-kinase family. When activated, Chk2 targets p53, BRCA1, Cdc25A and Cdc25C to cause cell cycle arrest. Chk2 is also known as serine/threonine-protein kinase CHK2, CHEK2, CDS1, LFS2, Rad53, HuCds1, and PP1425.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-619A maps to a region between residues 475 and 525 of human Checkpoint Kinase 2 using the numbering given in entry NP_009125.1 (GeneID 11200).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-620A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Chk2 functions as a checkpoint protein kinase in response to DNA damage to maintain genomic stability. The yeast homologs are Rad53 and Cds1. The two major upstream controllers of Chk2 are ATM and ATR which are part of the phosphatidylinositol 3-kinase family. When activated, Chk2 targets p53, BRCA1, Cdc25A and Cdc25C to cause cell cycle arrest. Chk2 is also known as serine/threonine-protein kinase CHK2, CHEK2, CDS1, LFS2, Rad53, HuCds1, and PP1425.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-619A maps to a region between residue 500 and the C-terminus (residue 543) of human Checkpoint Kinase 2 using the numbering given in entry NP_009125.1 (GeneID 11200).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-182A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibody was affinity purified using an epitope specific to Chk2 immobilized on solid support.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

729 €

IHC-00043
IHC Erklärungen der Abkürzungen ansehen.
Chk2 functions as a checkpoint protein kinase in response to DNA damage to maintain genomic stability. The yeast homologs are Rad53 and Cds1. The two major upstream controllers of Chk2 are ATM and ATR which are part of the phosphatidylinositol 3-kinase family. When activated, Chk2 targets p53, BRCA1, Cdc25A and Cdc25C to cause cell cycle arrest. Chk2 is also known as serine/threonine-protein kinase CHK2, CHEK2, CDS1, LFS2, Rad53, HuCds1, and PP1425.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00043 maps to a region between residue 475 and 525 of human Checkpoint Kinase 2 using the numbering given in entry NP_009125.1 (GeneID 11200).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A302-683A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
LYN is a tyrosine protein kinase that acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between proliferation and maturation. LYN acts as the mediator that relays suppressing signals from the chemokine receptor CXCR4 to beta-2 integrin LFA-1 in hematopoietic precursors. It is involved in induction of stress-activated protein kinase (SAPK), but not ERK or p38 MAPK, in response to genotoxic agents. LYN induces SAPK by a MKK7- and MEKK1-dependent mechanism. Alternate names for LYN include v-yes-1 Yamaguchi sarcoma viral related oncogene homolog, JTK8, and FLJ26625. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P07948]

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A302-683A maps to a region between residue 1 and 50 of human v-yes-1 Yamaguchi sarcoma viral related oncogene homolog using the numbering given in entry NP_002341.1 (GeneID 4067).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-252A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
c-Kit is the receptor for stem cell factor (mast cell growth factor). It is a transmembrane receptor with tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of the c-Kit receptor and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K). Alternative names for c-Kit include, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, mast/stem cell growth factor receptor, proto-oncogene c-Kit, CD_antigen 117, CD117, KIT, PBT, and SCFR. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P10721]

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A303-252A maps to a region between residue 925 and 976 of c-Kit using the numbering given in entry NP_000213.1 (GeneID 3815).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-133A
related products

WB Erklärungen der Abkürzungen ansehen.
Filamin A is an actin-binding protein that crosslinks and promotes orthogonal branching of actin filaments and also functions to anchor transmembrane proteins and intracellular signaling proteins to the actin cytoskeleton. As a scaffolding protein, filamin A is able to act as a link between cell membrane receptors and intracellular signaling proteins. Defects in Filamin A are associated with multiple human diseases characterized by abnormalities in bone and neurological development. Alternate names for Filamin A include filamin-A, alpha-filamin, filamin-1, endothelial actin-binding protein, actin-binding protein 280, ABP-280, nonmuscle filamin, FLNA, FLN, FLN1, FMD, MNS, OPD, ABPX, NHBP, OPD1, OPD2, and ABP-280.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-133A maps to a region between residue 400 and 450 of human Filamin A using the numbering given in entry NP_001447.1 (GeneID 2316).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-134A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Filamin A is an actin-binding protein that crosslinks and promotes orthogonal branching of actin filaments and also functions to anchor transmembrane proteins and intracellular signaling proteins to the actin cytoskeleton. As a scaffolding protein, filamin A is able to act as a link between cell membrane receptors and intracellular signaling proteins. Defects in Filamin A are associated with multiple human diseases characterized by abnormalities in bone and neurological development. Alternate names for Filamin A include filamin-A, alpha-filamin, filamin-1, endothelial actin-binding protein, actin-binding protein 280, ABP-280, nonmuscle filamin, FLNA, FLN, FLN1, FMD, MNS, OPD, ABPX, NHBP, OPD1, OPD2, and ABP-280.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A301-134A maps to a region between residue 1725 and 1775 of human Filamin A using the numbering given in entry NP_001447.1 (GeneID 2316).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-135A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Filamin A is an actin-binding protein that crosslinks and promotes orthogonal branching of actin filaments and also functions to anchor transmembrane proteins and intracellular signaling proteins to the actin cytoskeleton. As a scaffolding protein, filamin A is able to act as a link between cell membrane receptors and intracellular signaling proteins. Defects in Filamin A are associated with multiple human diseases characterized by abnormalities in bone and neurological development. Alternate names for Filamin A include filamin-A, alpha-filamin, filamin-1, endothelial actin-binding protein, actin-binding protein 280, ABP-280, nonmuscle filamin, FLNA, FLN, FLN1, FMD, MNS, OPD, ABPX, NHBP, OPD1, OPD2, and ABP-280.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A301-135A maps to a region between residue 2597 and 2647 of human Filamin A using the numbering given in entry NP_001447.1 (GeneID 2316).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-374A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to Filamin A immobilized on solid support.

Rabbit IgG SR: human, mouse
Bethyl
Icon Datasheet
1 pack

Buy Bulk

729 €

IHC-00225
IHC Erklärungen der Abkürzungen ansehen.
Filamin A is an actin-binding protein that crosslinks and promotes orthogonal branching of actin filaments and also functions to anchor transmembrane proteins and intracellular signaling proteins to the actin cytoskeleton. As a scaffolding protein, filamin A is able to act as a link between cell membrane receptors and intracellular signaling proteins. Defects in Filamin A are associated with multiple human diseases characterized by abnormalities in bone and neurological development. Alternate names for Filamin A include filamin-A, alpha-filamin, filamin-1, endothelial actin-binding protein, actin-binding protein 280, ABP-280, nonmuscle filamin, FLNA, FLN, FLN1, FMD, MNS, OPD, ABPX, NHBP, OPD1, OPD2, and ABP-280.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00225 maps to a region between residue 1725 and 1775 of human Filamin A using the numbering given in entry NP_001447.1 (GeneID 2316).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A301-823A
IP, PLA Erklärungen der Abkürzungen ansehen.
RelA, also known as p52, is one of five monomeric subunits that are part of the Rel family of proteins that dimerize to form the NF-kappa B (nuclear factor that binds the kappa immunoglobulin light chain gene enhancer) transcription factor. Members of the Rel family of proteins include NF-kappa B1/p50, NF-kappa B2/p52, RelA/p65, c-Rel, and RelB. Each Rel member bears a characteristic 300 amino acid N-terminal Rel homology domain (RHD) that functions to mediate DNA binding, dimerization, nuclear localization, and inhibitor association.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-823A maps to a region between residue 1 and 50 of human reticuloendotheliosis viral oncogene homolog A using the numbering given in entry NP_068810.2 (GeneID 5970).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A302-062A
related products

WB Erklärungen der Abkürzungen ansehen.
The epitope recognized by A302-062A maps to a region of human v-rel reticuloendotheliosis viral oncogene homolog A surrounding serine 536 when serine 536 is phosphorylated using the numbering given in entry NP_068810.2 (GeneID 5970).

Rabbit IgG SR: human
Immunogen: synthetic phospho-peptide. The epitope recognized by A302-062A maps to a region of human v-rel reticuloendotheliosis viral oncogene homolog A surrounding serine 536 when serine 536 is phosphorylated using the numbering given in entry NP_068810.2 (GeneID 5
Bethyl
Icon Datasheet
100 µl

Buy Bulk

417 €

A302-063A
related products

WB Erklärungen der Abkürzungen ansehen.
The epitope recognized by A302-063A maps to a region of human v-rel reticuloendotheliosis viral oncogene homolog A surrounding serine 529 when serine 529 is phosphorylated using the numbering given in entry NP_068810.2 (GeneID 5970).

Rabbit IgG SR: human
Immunogen: synthetic phospho-peptide. The epitope recognized by A302-063A maps to a region of human v-rel reticuloendotheliosis viral oncogene homolog A surrounding serine 529 when serine 529 is phosphorylated using the numbering given in entry NP_068810.2 (GeneID 5
Bethyl
Icon Datasheet
100 µl

Buy Bulk

417 €

A302-064A
related products

WB, PLA Erklärungen der Abkürzungen ansehen.
The epitope recognized by A302-064A maps to a region of human v-rel reticuloendotheliosis viral oncogene homolog A surrounding serine 468 when serine 468 is phosphorylated using the numbering given in entry NP_068810.2 (GeneID 5970).

Rabbit IgG SR: human
Immunogen: synthetic phospho-peptide. The epitope recognized by A302-064A maps to a region of human v-rel reticuloendotheliosis viral oncogene homolog A surrounding serine 468 when serine 468 is phosphorylated using the numbering given in entry NP_068810.2 (GeneID 5
Bethyl
Icon Datasheet
100 µl

Buy Bulk

417 €

A303-945A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
RelA, is one of five monomeric subunits that are part of the Rel family of proteins that dimerize to form the NF-kappa B (nuclear factor that binds the kappa immunoglobulin light chain gene enhancer) transcription factor. Members of the Rel family of proteins include NF-kappa B1/p50, NF-kappa B2/p52, RelA/p65, c-Rel, and RelB. Each Rel member bears a characteristic 300 amino acid N-terminal Rel homology domain (RHD) that functions to mediate DNA binding, dimerization, nuclear localization, and inhibitor association.

Goat IgG SR: human, mouse
Immunogen: Synthetic peptide. The epitope recognized by A303-945A maps to a region between residue 501 to 551 of human Reticuloendotheliosis Viral Oncogene Homolog A using the numbering given in entry NP_068810.2 (GeneID 5970).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-650A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A301-823A and A301-824A

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

IHC-00520
IHC Erklärungen der Abkürzungen ansehen.
RelA, also known as p52, is one of five monomeric subunits that are part of the Rel family of proteins that dimerize to form the NF-kappa B (nuclear factor that binds the kappa immunoglobulin light chain gene enhancer) transcription factor. Members of the Rel family of proteins include NF-kappa B1/p50, NF-kappa B2/p52, RelA/p65, c-Rel, and RelB. Each Rel member bears a characteristic 300 amino acid N-terminal Rel homology domain (RHD) that functions to mediate DNA binding, dimerization, nuclear localization, and inhibitor association.

Rabbit SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00520 maps to a region between residue 501 and 551 of human reticuloendotheliosis viral oncogene homolog A using the numbering given in entry NP_068810.2 (GeneID 5970).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

IHC-00524
IHC Erklärungen der Abkürzungen ansehen.
RelA, also known as p52, is one of five monomeric subunits that are part of the Rel family of proteins that dimerize to form the NF-kappa B (nuclear factor that binds the kappa immunoglobulin light chain gene enhancer) transcription factor. Members of the Rel family of proteins include NF-kappa B1/p50, NF-kappa B2/p52, RelA/p65, c-Rel, and RelB. Each Rel member bears a characteristic 300 amino acid N-terminal Rel homology domain (RHD) that functions to mediate DNA binding, dimerization, nuclear localization, and inhibitor association.

Rabbit SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00524 maps to a region of human v-rel reticuloendotheliosis viral oncogene homolog A surrounding serine 536 when serine 536 is phosphorylated using the numbering given in entry NP_068810.2 (GeneID 5970).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

429 €

IHC-00525
IHC Erklärungen der Abkürzungen ansehen.
RelA, also known as p52, is one of five monomeric subunits that are part of the Rel family of proteins that dimerize to form the NF-kappa B (nuclear factor that binds the kappa immunoglobulin light chain gene enhancer) transcription factor. Members of the Rel family of proteins include NF-kappa B1/p50, NF-kappa B2/p52, RelA/p65, c-Rel, and RelB. Each Rel member bears a characteristic 300 amino acid N-terminal Rel homology domain (RHD) that functions to mediate DNA binding, dimerization, nuclear localization, and inhibitor association.

Rabbit SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00525 maps to a region of human v-rel reticuloendotheliosis viral oncogene homolog A surrounding serine 468 when serine 468 is phosphorylated using the numbering given in entry NP_068810.2 (GeneID 5970).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

429 €

A300-070A
IP, IHC Erklärungen der Abkürzungen ansehen.
Aurora A is a serine-threonine protein kinase that localizes to centrosomes and spindle poles and is important to spindle assembly and chromosome congression. Substrates of Aurora A kinase activity include BRCA1, CDC25B, and NDEL1. Aurora A has been found to be overexpressed in human cancers. Alternate designations for Aurora A include serine/threonine-protein kinase 6, Aurora kinase A, Aurora A, serine/threonine kinase 15, Aurora/IPL1-related kinase 1, Aurora-related kinase 1, hARK1, breast tumor-amplified kinase, AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6, STK7, AURORA2, and MGC34538.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-070A maps to a region between residues 50 and 100 of human Aurora A Kinase using the numbering given in entry NP_003591.2 (GeneID 6790).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-071A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Aurora A is a serine-threonine protein kinase that localizes to centrosomes and spindle poles and is important to spindle assembly and chromosome congression. Substrates of Aurora A kinase activity include BRCA1, CDC25B, and NDEL1. Aurora A has been found to be overexpressed in human cancers. Alternate designations for Aurora A include serine/threonine-protein kinase 6, Aurora kinase A, Aurora A, serine/threonine kinase 15, Aurora/IPL1-related kinase 1, Aurora-related kinase 1, hARK1, breast tumor-amplified kinase, AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6, STK7, AURORA2, and MGC34538.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-071A maps to a region between residues 75 and 125 of human Aurora A Kinase using the numbering given in entry NP_003591.2 (GeneID 6790).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-018A
related products

WB, IP, IF Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to Aurora A immobilized on solid support.

Rabbit IgG SR: human, mouse, rat
Bethyl
Icon Datasheet
1 pack

Buy Bulk

729 €

IHC-00062
ICC Erklärungen der Abkürzungen ansehen.
Aurora A is a serine-threonine protein kinase that localizes to centrosomes and spindle poles and is important to spindle assembly and chromosome congression. Substrates of Aurora A kinase activity include BRCA1, CDC25B, and NDEL1. Aurora A has been found to be overexpressed in human cancers. Alternate designations for Aurora A include serine/threonine-protein kinase 6, Aurora kinase A, Aurora A, serine/threonine kinase 15, Aurora/IPL1-related kinase 1, Aurora-related kinase 1, hARK1, breast tumor-amplified kinase, AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6, STK7, AURORA2, and MGC34538.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00062 maps to a region between residue 75 and 125 of human Aurora A Kinase using the numbering given in entry NP_003591.2 (GeneID 6790).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

IHC-00067
ICC Erklärungen der Abkürzungen ansehen.
Aurora A is a serine-threonine protein kinase that localizes to centrosomes and spindle poles and is important to spindle assembly and chromosome congression. Substrates of Aurora A kinase activity include BRCA1, CDC25B, and NDEL1. Aurora A has been found to be overexpressed in human cancers. Alternate designations for Aurora A include serine/threonine-protein kinase 6, Aurora kinase A, Aurora A, serine/threonine kinase 15, Aurora/IPL1-related kinase 1, Aurora-related kinase 1, hARK1, breast tumor-amplified kinase, AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6, STK7, AURORA2, and MGC34538.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00067 maps to a region surrounding residue 288 when Threonine 288 is phosphorylated of human Aurora A Kinase using the numbering given entry NP_003591.2 (GeneID 6790).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

429 €

S300-070
IP Erklärungen der Abkürzungen ansehen.
Rabbit anti-human Aurora A affinity purified Antibodies were coupled to agarose beads using a cyanogen bromide method.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
100 µg

Buy Bulk

367 €

S300-071
IP Erklärungen der Abkürzungen ansehen.
Rabbit anti-human Aurora A affinity purified antibodies were coupled to agarose beads using a cyanogen bromide method.

Rabbit IgG SR: human
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
100 µg

Buy Bulk

367 €

A300-503A
IP, ICC Erklärungen der Abkürzungen ansehen.
Studies of the mammalian target of rapamycin (mTOR) and its homologs demonstrate a role in integrating signals from growth factors, nutrients, stress, and cellular energy levels to control cell growth, translation initiation, ribosome biogenesis, and transcription factor localization. mTOR is the direct target of the cell cycle arresting activity of rapamycin. mTOR interacts with Raptor or Rictor to form the mTORC1 and mTORC2 complexes respectively. The mTORC1 complex also includes mLst8/GbetaL and functions to phosphorylate S6K and 4EBP1. The mTORC2 complex also includes mLst8/GbetaL, mSIN1 and protor-1 and functions to phosphorylate Akt. mTOR is also known as FKBP12-rapamycin complex-associated protein, FK506-binding protein 12-rapamycin complex-associated protein 1, rapamycin target protein, FRAP, FRAP1, FRAP2, RAFT1, RAPT1, and FLJ44809.

Rabbit IgG SR: human, rat
Immunogen: synthetic peptide. The epitope recognized by A300-503A maps to a region between residue 200 and 250 of human Mammalian Target of Rapamycin using the numbering given in entry NP_004949.1 (GeneID 2475).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-504A
related products

WB Erklärungen der Abkürzungen ansehen.
Studies of the mammalian target of rapamycin (mTOR) and its homologs demonstrate a role in integrating signals from growth factors, nutrients, stress, and cellular energy levels to control cell growth, translation initiation, ribosome biogenesis, and transcription factor localization. mTOR is the direct target of the cell cycle arresting activity of rapamycin. mTOR interacts with Raptor or Rictor to form the mTORC1 and mTORC2 complexes respectively. The mTORC1 complex also includes mLst8/GbetaL and functions to phosphorylate S6K and 4EBP1. The mTORC2 complex also includes mLst8/GbetaL, mSIN1 and protor-1 and functions to phosphorylate Akt. mTOR is also known as FKBP12-rapamycin complex-associated protein, FK506-binding protein 12-rapamycin complex-associated protein 1, rapamycin target protein, FRAP, FRAP1, FRAP2, RAFT1, RAPT1, and FLJ44809.

Rabbit IgG SR: human, rat, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-504A maps to a region between residue 200 and 250 of human Mammalian Target of Rapamycin using the numbering given in entry NP_004949.1 (GeneID 2475).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-142A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Studies of the mammalian target of rapamycin (mTOR) and its homologs demonstrate a role in integrating signals from growth factors, nutrients, stress, and cellular energy levels to control cell growth, translation initiation, ribosome biogenesis, and transcription factor localization. mTOR is the direct target of the cell cycle arresting activity of rapamycin. mTOR interacts with Raptor or Rictor to form the mTORC1 and mTORC2 complexes respectively. The mTORC1 complex also includes mLst8/GbetaL and functions to phosphorylate S6K and 4EBP1. The mTORC2 complex also includes mLst8/GbetaL, mSIN1 and protor-1 and functions to phosphorylate Akt. mTOR is also known as FKBP12-rapamycin complex-associated protein, FK506-binding protein 12-rapamycin complex-associated protein 1, rapamycin target protein, FRAP, FRAP1, FRAP2, RAFT1, RAPT1, and FLJ44809.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A301-142A maps to a region between residue 1125 and 1175 of human mammalian target of rapamycin using the numbering given in entry NP_004949.1 (GeneID 2475).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-143A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Studies of the mammalian target of rapamycin (mTOR) and its homologs demonstrate a role in integrating signals from growth factors, nutrients, stress, and cellular energy levels to control cell growth, translation initiation, ribosome biogenesis, and transcription factor localization. mTOR is the direct target of the cell cycle arresting activity of rapamycin. mTOR interacts with Raptor or Rictor to form the mTORC1 and mTORC2 complexes respectively. The mTORC1 complex also includes mLst8/GbetaL and functions to phosphorylate S6K and 4EBP1. The mTORC2 complex also includes mLst8/GbetaL, mSIN1 and protor-1 and functions to phosphorylate Akt. mTOR is also known as FKBP12-rapamycin complex-associated protein, FK506-binding protein 12-rapamycin complex-associated protein 1, rapamycin target protein, FRAP, FRAP1, FRAP2, RAFT1, RAPT1, and FLJ44809.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A301-143A maps to a region between residue 1350 and 1400 of human mammalian target of rapamycin using the numbering given in entry NP_004949.1 (GeneID 2475).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-144A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Studies of the mammalian target of rapamycin (mTOR) and its homologs demonstrate a role in integrating signals from growth factors, nutrients, stress, and cellular energy levels to control cell growth, translation initiation, ribosome biogenesis, and transcription factor localization. mTOR is the direct target of the cell cycle arresting activity of rapamycin. mTOR interacts with Raptor or Rictor to form the mTORC1 and mTORC2 complexes respectively. The mTORC1 complex also includes mLst8/GbetaL and functions to phosphorylate S6K and 4EBP1. The mTORC2 complex also includes mLst8/GbetaL, mSIN1 and protor-1 and functions to phosphorylate Akt. mTOR is also known as FKBP12-rapamycin complex-associated protein, FK506-binding protein 12-rapamycin complex-associated protein 1, rapamycin target protein, FRAP, FRAP1, FRAP2, RAFT1, RAPT1, and FLJ44809.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-144A maps to a region between residue 1675 and 1725 of human mammalian target of rapamycin using the numbering given in entry NP_004949.1 (GeneID 2475).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-114A
related products

WB, IP, ICC Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to mTOR immobilized on solid support.

Rabbit IgG SR: human, mouse, rat
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A310-378A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to mTOR immobilized on solid support.

Rabbit IgG SR: human, mouse
Bethyl
Icon Datasheet
1 pack

Buy Bulk

729 €

S300-503
IP Erklärungen der Abkürzungen ansehen.
Rabbit anti-human mTOR affinity purified Antibodies were coupled to agarose beads using a cyanogen bromide method.

Rabbit IgG SR: human, rat
Bethyl
Icon Datasheet
100 µg

Buy Bulk

367 €

S300-504
IP Erklärungen der Abkürzungen ansehen.
Rabbit anti-human mTOR affinity purified Antibodies were coupled to agarose beads using a cyanogen bromide method.

Rabbit IgG SR: human, rat
Bethyl
Icon Datasheet
100 µg

Buy Bulk

367 €

S301-144
IP Erklärungen der Abkürzungen ansehen.
Rabbit anti-mTOR affinity purified antibodies were coupled to agarose beads using a cyanogen bromide method.

Rabbit IgG SR: human
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
100 µg

Buy Bulk

367 €

A303-803A
related products

WB Erklärungen der Abkürzungen ansehen.
TNF receptor-associated factor 6 (TRAF6) is an E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, AKT1 and AKT2. TRAF6 also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. TRAF6 leads to the activation of NF-kappa-B and JUN. TRAF6 may be essential for the formation of functional osteoclasts, and it regulates osteoclast differentiation by mediating the activation of adapter protein complex 1 (AP-1) and NF-kappa-B, in response to RANK-L stimulation. TRAF6 also seems to play a role in dendritic cells (DCs) maturation and/or activation. TRAF6 represses c-Myb-mediated transactivation, in B-lymphocytes. TRAF6 is an adapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y4K3].

Rabbit IgG SR: human
Immunogen: Synthetic peptide. The epitope recognized by A303-803A maps to a region between residue 472 and 522 of human TNF Receptor-Associated Factor 6 using the numbering given in entry NP_004611.1 (GeneID 7189).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-519A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
RAF1 is a mitogen activated kinase kinase kinase (MAPKKK). In response to extracellular signals, RAF1 phosphorylates the MEK1 and MEK2 MAP kinase kinases. MEK1 and MEK2 subsequently phosphorylate and activate the ERK1 and ERK2 MAP kinases to exert pleiotropic effects on cellular functions such as growth, division, differentiation, motility, and apoptosis. RAF1 associates with the Ras family of membrane GTPases and functions downstream of Ras activity. Alternate names for RAF1 include RAF proto-oncogene serine/threonine-protein kinase, v-raf-1 murine leukemia viral oncogene homolog 1, Raf-1, C-RAF, and cRaf.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A301-519A maps to a region between residue 598 and 648 of human v-raf-1 murine leukemia viral oncogene homolog 1 using the numbering given in entry NP_002871.1 (GeneID 5894).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-979A
IP Erklärungen der Abkürzungen ansehen.
Adenomatosis polyposis coli (APC) is a tumor suppressor gene found to be mutated in most colon cancers and is the cause of familial adenomatous polyposis (FAP), an autosomal dominant disease that results in a predisposition to malignant colon cancer. APC has been shown to be involved in cell differentiation, migration, proliferation and adhesion. One function of APC involves its role as a scaffolding protein that regulates the phosphorylation and degradation of beta-catenin, a transcriptional regulator in the WNT signaling pathway. Additionally, APC has been found to be important in the regulation of microtubule arrays and mitotic spindle formation. Alternate designations for APC include DP2.5, DP2, GS, FAP, FPC, and DP3.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-979A maps to a region between residue 1 and 50 of human adenomatosis polyposis coli using the numbering given in entry NP_000029.2 (GeneID 324).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-980A
IP Erklärungen der Abkürzungen ansehen.
Adenomatosis polyposis coli (APC) is a tumor suppressor gene found to be mutated in most colon cancers and is the cause of familial adenomatous polyposis (FAP), an autosomal dominant disease that results in a predisposition to malignant colon cancer. APC has been shown to be involved in cell differentiation, migration, proliferation and adhesion. One function of APC involves its role as a scaffolding protein that regulates the phosphorylation and degradation of beta-catenin, a transcriptional regulator in the WNT signaling pathway. Additionally, APC has been found to be important in the regulation of microtubule arrays and mitotic spindle formation. Alternate designations for APC include DP2.5, DP2, GS, FAP, FPC, and DP3.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-980A maps to a region between residue 75 and 125 of human adenomatosis polyposis coli using the numbering given in entry NP_000029.2 (GeneID 324).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-981A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Adenomatosis polyposis coli (APC) is a tumor suppressor gene found to be mutated in most colon cancers and is the cause of familial adenomatous polyposis (FAP), an autosomal dominant disease that results in a predisposition to malignant colon cancer. APC has been shown to be involved in cell differentiation, migration, proliferation and adhesion. One function of APC involves its role as a scaffolding protein that regulates the phosphorylation and degradation of beta-catenin, a transcriptional regulator in the WNT signaling pathway. Additionally, APC has been found to be important in the regulation of microtubule arrays and mitotic spindle formation. Alternate designations for APC include DP2.5, DP2, GS, FAP, FPC, and DP3.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-981A maps to a region between residue 2793 and the C-terminus (residue 2843) of human adenomatosis polyposis coli using the numbering given in entry NP_000029.2 (GeneID 324).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-318A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to APC immobilized on solid support.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

729 €

IHC-00252
IHC Erklärungen der Abkürzungen ansehen.
Adenomatosis polyposis coli (APC) is a tumor suppressor gene found to be mutated in most colon cancers and is the cause of familial adenomatous polyposis (FAP), an autosomal dominant disease that results in a predisposition to malignant colon cancer. APC has been shown to be involved in cell differentiation, migration, proliferation and adhesion. One function of APC involves its role as a scaffolding protein that regulates the phosphorylation and degradation of beta-catenin, a transcriptional regulator in the WNT signaling pathway. Additionally, APC has been found to be important in the regulation of microtubule arrays and mitotic spindle formation. Alternate designations for APC include DP2.5, DP2, GS, FAP, FPC, and DP3.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00252 maps to a region between residue 1 and 50 of human adenomatosis polyposis coli using the numbering given in entry NP_000029.2 (GeneID 324).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A301-827A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
IKK-beta (Inhibitor of nuclear factor kappa B kinase subunit beta) is one of three subunits that comprise the IKK complex. The IKK complex consists of two catalytic subunits, IKK-alpha and IKK-beta, and a regulatory subunit IKK-gamma/NEMO. As a kinase, IKK functions to phosphorylate members of the NF-kappa B inhibitor proteins, the I-kappa B proteins. Phosphorylation of I-kappa B proteins results in the ubiquitination and degradation of I kappa B and the release and translocation of the NF-kappa B transcription factor to the nucleus where it may function to activate a vast number of genes. Alternative names for IKK-beta include I kappa B kinase beta, I-kappa-B kinase 2, IKK2, NF-kappa B inhibitor kinase beta, NFKBIKB, and IKBKB.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-827A maps to a region between residue 706 and 756 of human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta using the numbering given in entry NP_001547.1 (GeneID 3551).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-022A
related products

WB, IP, ICC, IF, PLA Erklärungen der Abkürzungen ansehen.
MSH6 is a component of the DNA mismatch repair (MMR) system that functions to recognize base-base mismatches and framshift mispairs. MSH6 forms a heterodimer with MSH2 and is also part of the BRCA1-associated genome surveillance complex (BASC). Mutations in MSH6 have been linked to endometrial carcinoma. Alternate names for MSH6 include DNA mismatch repair protein MSH6, MutS-alpha 160 kDa subunit, G/T mismatch ?binding protein, GTBP, GTMBP, HSAP, and HNPCC5.

Goat IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-022A maps to a region between residues 350 and 400 of human MutS homolog 6 using the numbering given in entry NP_000170.1 (GeneID 2956).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-004A
related products

WB, IP, ICC Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to MSH6 immobilized on solid support.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

IHC-00119
IHC Erklärungen der Abkürzungen ansehen.
MSH6 is a component of the DNA mismatch repair (MMR) system that functions to recognize base-base mismatches and framshift mispairs. MSH6 forms a heterodimer with MSH2 and is also part of the BRCA1-associated genome surveillance complex (BASC). Mutations in MSH6 have been linked to endometrial carcinoma. Alternate names for MSH6 include DNA mismatch repair protein MSH6, MutS-alpha 160 kDa subunit, G/T mismatch ?binding protein, GTBP, GTMBP, HSAP, and HNPCC5.

Goat IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00119 maps to a region between residues 350 and 400 of human MutS homolog 6 using the numbering given in entry NP_000170.1 (GeneID 2956).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A300-588A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
Valosin-containing protein (VCP) is a multifunctional protein that is proposed to be involved in vesicle transport and fusion for protein trafficking, 26S proteasome function in ubiquitin-based degradation pathways, and the assembly of peroxisomes. Mutations in the human VCP gene have been associated with diseases such as inclusion body myopathy, Paget disease of the bone, and frontotemporal dementia (IBMPFD). VCP can inhibit apoptosis and may play a role in tumorigenesis. VCP is also known as, Transitional Endoplasmic Reticulum ATPase, TER ATPase, TERA, 15S Mg (2plus)-ATPase p97subunit, IBMPFD, Inclusion Body Myopathy associated with Paget Disease of Bone and Frontotemporal Dementia, MGC8560, MGC131997, MGC148092.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-588A maps to a region between residues 1 and 50 of human Valosin-Containing Protein using the numbering given in entry NP_009057.1 (GeneID 7415).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-589A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Valosin-containing protein (VCP) is a multifunctional protein that is proposed to be involved in vesicle transport and fusion for protein trafficking, 26S proteasome function in ubiquitin-based degradation pathways, and the assembly of peroxisomes. Mutations in the human VCP gene have been associated with diseases such as inclusion body myopathy, Paget disease of the bone, and frontotemporal dementia (IBMPFD). VCP can inhibit apoptosis and may play a role in tumorigenesis. VCP is also known as, Transitional Endoplasmic Reticulum ATPase, TER ATPase, TERA, 15S Mg (2plus)-ATPase p97subunit, IBMPFD, Inclusion Body Myopathy associated with Paget Disease of Bone and Frontotemporal Dementia, MGC8560, MGC131997, MGC148092.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-589A maps to a region between residue 750 and the C-terminus (residue 806) of human Valosin-Containing Protein using the numbering given in entry NP_009057.1 (GeneID 7415).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-174A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibody was affinity purified using an epitope specific to VCP immobilized on solid support.

Rabbit IgG SR: human, mouse
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

IHC-00084
IHC Erklärungen der Abkürzungen ansehen.
Valosin-containing protein (VCP) is a multifunctional protein that is proposed to be involved in vesicle transport and fusion for protein trafficking, 26S proteasome function in ubiquitin-based degradation pathways, and the assembly of peroxisomes. Mutations in the human VCP gene have been associated with diseases such as inclusion body myopathy, Paget disease of the bone, and frontotemporal dementia (IBMPFD). VCP can inhibit apoptosis and may play a role in tumorigenesis. VCP is also known as, Transitional Endoplasmic Reticulum ATPase, TER ATPase, TERA, 15S Mg (2plus)-ATPase p97subunit, IBMPFD, Inclusion Body Myopathy associated with Paget Disease of Bone and Frontotemporal Dementia, MGC8560, MGC131997, MGC148092.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by IHC-00084 maps to a region between residue 750 and the C-terminus (residue 806) of human Valosin-Containing Protein using the numbering given in entry NP_009057.1 (GeneID 7415).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A300-274A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
KAP-1 (KRAB-Associated Protein 1) is a member of the tripartite motif RBCC/Trim domain family that contains a RING finger domain, B boxes, and an alpha helical coiled coil region. KAP-1 functions as a corepressor by interacting with the KRAB domain of KRAB zinc-finger transcriptional repressors. KAP-1 also appears to function as a scaffold for chromatin-remodeling complexes involved in transcriptional repression. Alternate names for KAP-1 include transcription intermediary factor 1-beta, TIF1-beta, tripartite motif-containing protein 28, nuclear corepressor KAP-1, KRIP-1, TRIM28, RNF96, TIF1B, and FLJ29029.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-274A maps to a region between residue 1 and 50 of human Tripartite Motif-Containing 28 using the numbering given in entry NP_005753.1 (GeneID 10155).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-275A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
KAP-1 (KRAB-Associated Protein 1) is a member of the tripartite motif RBCC/Trim domain family that contains a RING finger domain, B boxes, and an alpha helical coiled coil region. KAP-1 functions as a corepressor by interacting with the KRAB domain of KRAB zinc-finger transcriptional repressors. KAP-1 also appears to function as a scaffold for chromatin-remodeling complexes involved in transcriptional repression. Alternate names for KAP-1 include transcription intermediary factor 1-beta, TIF1-beta, tripartite motif-containing protein 28, nuclear corepressor KAP-1, KRIP-1, TRIM28, RNF96, TIF1B, and FLJ29029.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-275A maps to a region between residue 650 and 700 of human Tripartite Motif-Containing 28 using the numbering given in entry NP_005753.1 (GeneID 10155).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-767A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
KAP-1 (KRAB-Associated Protein 1) is a member of the tripartite motif RBCC/Trim domain family that contains a RING finger domain, B boxes, and an alpha helical coiled coil region. KAP-1 functions as a corepressor by interacting with the KRAB domain of KRAB zinc-finger transcriptional repressors. KAP-1 also appears to function as a scaffold for chromatin-remodeling complexes involved in transcriptional repression. Alternate names for KAP-1 include transcription intermediary factor 1-beta, TIF1-beta, tripartite motif-containing protein 28, nuclear corepressor KAP-1, KRIP-1, TRIM28, RNF96, TIF1B, and FLJ29029.

Rabbit IgG SR: human
Immunogen: synthetic phospho-peptide. Immunogen was a synthetic phosphorylated peptide, which represented a portion of human KRAB-Associated Protein 1 surrounding Serine 824 according to the numbering given in entry NP_005753.1 (GeneID 10155).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

373 €

A303-838A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
KAP-1 (KRAB-Associated Protein 1) is a member of the tripartite motif RBCC/Trim domain family that contains a RING finger domain, B boxes, and an alpha helical coiled coil region. KAP-1 functions as a corepressor by interacting with the KRAB domain of KRAB zinc-finger transcriptional repressors. KAP-1 also appears to function as a scaffold for chromatin-remodeling complexes involved in transcriptional repression.

Goat IgG SR: human
Immunogen: Synthetic peptide. The epitope recognized by A303-838A maps to a region between residue 1 and 50 of human KRAB-Associated Protein 1 using the numbering given in entry NP_005753.1 (GeneID 10155).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-075A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to KAP-1 immobilized on solid support.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

IHC-00072
IHC, ICC Erklärungen der Abkürzungen ansehen.
KAP-1 (KRAB-Associated Protein 1) is a member of the tripartite motif RBCC/Trim domain family that contains a RING finger domain, B boxes, and an alpha helical coiled coil region. KAP-1 functions as a corepressor by interacting with the KRAB domain of KRAB zinc-finger transcriptional repressors. KAP-1 also appears to function as a scaffold for chromatin-remodeling complexes involved in transcriptional repression. Alternate names for KAP-1 include transcription intermediary factor 1-beta, TIF1-beta, tripartite motif-containing protein 28, nuclear corepressor KAP-1, KRIP-1, TRIM28, RNF96, TIF1B, and FLJ29029.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00072 maps to a region between residue 1 and 50 of human Tripartite Motif-Containing 28 using the numbering given in entry NP_005753.1 (GeneID 10155).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

IHC-00073
ICC Erklärungen der Abkürzungen ansehen.
KAP-1 (KRAB-Associated Protein 1) is a member of the tripartite motif RBCC/Trim domain family that contains a RING finger domain, B boxes, and an alpha helical coiled coil region. KAP-1 functions as a corepressor by interacting with the KRAB domain of KRAB zinc-finger transcriptional repressors. KAP-1 also appears to function as a scaffold for chromatin-remodeling complexes involved in transcriptional repression. Alternate names for KAP-1 include transcription intermediary factor 1-beta, TIF1-beta, tripartite motif-containing protein 28, nuclear corepressor KAP-1, KRIP-1, TRIM28, RNF96, TIF1B, and FLJ29029.

Rabbit IgG SR: human
Immunogen: synthetic phospho-peptide. Immunogen was a synthetic phosphorylated peptide, which represented a portion of human KRAB-Associated Protein 1 surrounding Serine 824 according to the numbering given in entry NP_005753.1 (GeneID 10155).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

429 €

A300-286A
related products

WB, IP, FC, PLA Erklärungen der Abkürzungen ansehen.
Hypoxia-inducible factor-1 (HIF1) is a basic helix-loop-helix (bHLH)-PER-ARNT-sim (PAS) transcription factor that plays a role in the cellular response to hypoxia. HIF1 is a heterodimer of an HIF1-alpha and HIF1-beta subunit. During normoxia, HIF-1alpha is regulated by ubiquitination and interaction with the von-Hippel-Lindau tumor suppressor protein (pVHL). Alternate names for HIF1-alpha include HIF-1 alpha, ARNT-interacting protein, member of PAS protein 1, basic-helix-loop-helix-PAS protein MOP1, HIF1A, MOP1, and PASD8.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-286A maps to a region between residues 775 and the C-terminus (residue 826) of human hypoxia-inducible factor 1, alpha subunit using the numbering given in Swiss-Prot entry Q16665 (GeneID 3091).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-907A
IP Erklärungen der Abkürzungen ansehen.
Hypoxia-inducible factor-1 (HIF1) is a basic helix-loop-helix (bHLH)-PER-ARNT-sim (PAS) transcription factor that plays a role in the cellular response to hypoxia. HIF1 is a heterodimer of an HIF1-alpha and HIF1-beta subunit. During normoxia, HIF-1alpha is regulated by ubiquitination and interaction with the von-Hippel-Lindau tumor suppressor protein (pVHL).

Goat IgG SR: human
Immunogen: Synthetic peptide. The epitope recognized by A303-907A maps to a region between residue 776 and 826 of human Hypoxia-Inducible Factor 1, Alpha Subunit using the numbering given in entry NP_001521.1 (GeneID 3091).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

IHC-00460
IHC Erklärungen der Abkürzungen ansehen.
Hypoxia-inducible factor-1 (HIF1) is a basic helix-loop-helix (bHLH)-PER-ARNT-sim (PAS) transcription factor that plays a role in the cellular response to hypoxia. HIF1 is a heterodimer of an HIF1-alpha and HIF1-beta subunit. During normoxia, HIF-1alpha is regulated by ubiquitination and interaction with the von-Hippel-Lindau tumor suppressor protein (pVHL). Alternate names for HIF1-alpha include HIF-1 alpha, ARNT-interacting protein, member of PAS protein 1, basic-helix-loop-helix-PAS protein MOP1, HIF1A, MOP1, and PASD8.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by IHC-00460 maps to a region between residues 775 and the C-terminus (residue 826) of human hypoxia-inducible factor 1, alpha subunit using the numbering given in Swiss-Prot entry Q16665 (GeneID 3091).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A300-362A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
CBP [cAMP response element-binding protein (CREB)-binding protein] interacts with and is a transcriptional co-activator of a multitude of transcriptional regulators that includes CREB. CBP is structurally and functionally similar to p300 but is encoded by an independent gene. CBP coactivation may be achieved through the regulation of chromatin structure due to its ability to catalyze the acetylation of histones. CBP has potential tumor suppressor properties and is important to integrating cell-signaling cues for proliferation, differentiation and apoptosis. CBP is also known as CREB-binding protein, CREBBP, RTS, and RSTS.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-362A maps to a region between residues 975 and 1025 of human CREB Binding Protein using the numbering given in entry NP_004371.1 (GeneID 1387).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-363A
IP Erklärungen der Abkürzungen ansehen.
CBP [cAMP response element-binding protein (CREB)-binding protein] interacts with and is a transcriptional co-activator of a multitude of transcriptional regulators that includes CREB. CBP is structurally and functionally similar to p300 but is encoded by an independent gene. CBP coactivation may be achieved through the regulation of chromatin structure due to its ability to catalyze the acetylation of histones. CBP has potential tumor suppressor properties and is important to integrating cell-signaling cues for proliferation, differentiation and apoptosis. CBP is also known as CREB-binding protein, CREBBP, RTS, and RSTS.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-363A maps to a region between residues 2375 and 2425 of human CREB Binding Protein using the numbering given in entry NP_004371.1 (GeneID 1387).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-098A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to CBP immobilized on solid support.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

IHC-00023
IHC Erklärungen der Abkürzungen ansehen.
CBP [cAMP response element-binding protein (CREB)-binding protein] interacts with and is a transcriptional co-activator of a multitude of transcriptional regulators that includes CREB. CBP is structurally and functionally similar to p300 but is encoded by an independent gene. CBP coactivation may be achieved through the regulation of chromatin structure due to its ability to catalyze the acetylation of histones. CBP has potential tumor suppressor properties and is important to integrating cell-signaling cues for proliferation, differentiation and apoptosis. CBP is also known as CREB-binding protein, CREBBP, RTS, and RSTS.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00023 maps to a region between residue 2375 and 2425 of human CREB Binding Protein using the numbering given in entry NP_004371.11 (GeneID 1387).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A303-785A
IP Erklärungen der Abkürzungen ansehen.
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Beta-arrestin 2, like beta-arrestin 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for beta-arrestin 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. [taken from NCBI Entrez Gene (Gene ID: 409)].

Rabbit IgG SR: human
Immunogen: Synthetic peptide. The epitope recognized by A303-785A maps to a region between residue 310 and 360 of human Arrestin, Beta 2 using the numbering given in entry NP_004304.1 (GeneID 409).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-786A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Beta-arrestin 2, like beta-arrestin 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for beta-arrestin 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. [taken from NCBI Entrez Gene (Gene ID: 409)].

Rabbit IgG SR: human
Immunogen: Synthetic peptide. The epitope recognized by A303-786A maps to a region between residue 355 and 405 of human Arrestin, Beta 2 using the numbering given in entry NP_004304.1 (GeneID 409).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A311-391A
WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A303-785A and A303-786A

Rabbit IgG SR: human
Immunogen: Synthetic peptide. Antibodies were affinity purified using epitopes specific to Beta-Arrestin 2 immobilized on solid support.
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A300-666A
IP Erklärungen der Abkürzungen ansehen.
ErbB4 is a member of the receptor tyrosine kinase family of proteins. The four members of this family are ErbB1 (Epidermal growth factor receptor, EGFR/HER1), ErbB2 (HER2/Neu), ErbB3 (HER3), and ErbB4 (HER4). The ErbB receptor members are single-pass transmembrane proteins with an extracellular ligand-binding domain and a cytoplasmic tyrosine-kinase domain. The epidermal growth factor (EGF) and its related proteins serve as the ligands for the ErbB receptors. Upon binding, the receptors homo- or heterodimerize, autophosphorylate and make contact with adapter molecules to transmit cellular signals involved in cell proliferation, survival, and differentiation. The ligands preferred by ErbB4 include neuregulins (NRG-2 and NRG-3), heparin-binding EGF-like growth factor, and betacellulin, and epiregulin. ErbB4 appears to be important to mammary gland development and lactation, however its role in breast cancer has not been unequivocally determined.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-666A maps to a region between residues 1100 and 1150 of human v-erb-a erythroblastic leukemia viral oncogene homolog 4 using the numbering given in entry NP_005226.1 (GeneID 2066).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-667A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
ErbB4 is a member of the receptor tyrosine kinase family of proteins. The four members of this family are ErbB1 (Epidermal growth factor receptor, EGFR/HER1), ErbB2 (HER2/Neu), ErbB3 (HER3), and ErbB4 (HER4). The ErbB receptor members are single-pass transmembrane proteins with an extracellular ligand-binding domain and a cytoplasmic tyrosine-kinase domain. The epidermal growth factor (EGF) and its related proteins serve as the ligands for the ErbB receptors. Upon binding, the receptors homo- or heterodimerize, autophosphorylate and make contact with adapter molecules to transmit cellular signals involved in cell proliferation, survival, and differentiation. The ligands preferred by ErbB4 include neuregulins (NRG-2 and NRG-3), heparin-binding EGF-like growth factor, and betacellulin, and epiregulin. ErbB4 appears to be important to mammary gland development and lactation, however its role in breast cancer has not been unequivocally determined.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-667A maps to a region between residue 1250 and the C-terminus (residue 1308) of human v-erb-a erythroblastic leukemia viral oncogene homolog 4 using the numbering given in entry NP_005226.1 (GeneID 2066).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-195A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibody was affinity purified using an epitope specific to ErbB4 immobilized on solid support.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A302-060A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Extracellular signal-regulated kinase 1 (ERK1/p44) is also known as mitogen-activated protein kinase 3 (MAPK3). ERK1 is part of a signal transduction pathway that begins with the small GTPase Ras and continues through a cascade of protein kinases that include Raf and MEK. Activation of this signaling pathway influences many cellular processes such as proliferation, differentiation and survival. ERK1 is very similar in sequence to ERK2/p42 and the activities of both ERK1 and ERK2 are usually considered together as total ERK activity. More recent evidence has shown that ERK1 and ERK2 are not functionally redundant and may have very different and specific roles. Alternate names for ERK1 include p44-MAPK, ERT2, p44-ERK1, MAPK 1, microtubule-associated protein kinase 2, and PRKM3.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A302-060A maps to a region between residue 329 and 379 of human extracellular signal-related kinase 1 (mitogen-activated protein kinase 3) using the numbering given in entry NP_002737.2 (GeneID 5595).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-608A
related products

WB Erklärungen der Abkürzungen ansehen.
Extracellular signal-regulated kinase 1 (ERK1/p44), also known as mitogen-activated protein kinase 3 (MAPK3), and extracellular signal-regulated kinase 2 (ERK2/p42), also known as mitogen-activated protein kinase 1 (MAPK1), are part of a signal transduction pathway that begins with the small GTPase Ras and continues through a cascade of protein kinases that include Raf and MEK. Activation of this signaling pathway influences many cellular processes such as proliferation, differentiation and survival. ERK1 is very similar in sequence to ERK2/p42 and the activities of both ERK1 and ERK2 are usually considered together as total ERK activity. More recent evidence has shown that ERK1 and ERK2 are not functionally redundant and may have very different and specific roles. Alternate names for ERK1 include p44-MAPK, ERT2, p44-ERK1, MAPK 1, microtubule-associated protein kinase 2, and PRKM3. Alternative names for ERK2 include p42-MAPK, ERT1, MAPK2, PRKM1, and PRKM2.

Rabbit IgG SR: human
Immunogen: Synthetic peptide. The epitope recognized by A303-608A maps to a region of human Extracellular Signal-Regulated Kinase-1 surrounding threonine 202 and tyrosine 204 (when using the numbering according to NCBI entry NP_002737.2, GeneID 5595) and human Extra
Bethyl
Icon Datasheet
100 µl

Buy Bulk

373 €

A303-609A
IP Erklärungen der Abkürzungen ansehen.
Extracellular signal-regulated kinase 1 (ERK1/p44), also known as mitogen-activated protein kinase 3 (MAPK3), and extracellular signal-regulated kinase 2 (ERK2/p42), also known as mitogen-activated protein kinase 1 (MAPK1), are part of a signal transduction pathway that begins with the small GTPase Ras and continues through a cascade of protein kinases that include Raf and MEK. Activation of this signaling pathway influences many cellular processes such as proliferation, differentiation and survival. ERK1 is very similar in sequence to ERK2/p42 and the activities of both ERK1 and ERK2 are usually considered together as total ERK activity. More recent evidence has shown that ERK1 and ERK2 are not functionally redundant and may have very different and specific roles. Alternate names for ERK1 include p44-MAPK, ERT2, p44-ERK1, MAPK 1, microtubule-associated protein kinase 2, and PRKM3. Alternative names for ERK2 include p42-MAPK, ERT1, MAPK2, PRKM1, and PRKM2.

Goat IgG SR: human
Immunogen: Synthetic peptide. The epitope recognized by A303-608A maps to a region of human Extracellular Signal-Regulated Kinase-1 surrounding threonine 202 and tyrosine 204 (when using the numbering according to NCBI entry NP_002737.2, GeneID 5595) and human Extra
Bethyl
Icon Datasheet
100 µl

Buy Bulk

373 €

A311-325A
WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A303-608A and A303-609A
IgG SR: human
Immunogen: Synthetic peptide.
Bethyl
Icon Datasheet
1 pack

Buy Bulk

585 €

IHC-00505
IHC Erklärungen der Abkürzungen ansehen.
Extracellular signal-regulated kinase 1 (ERK1/p44) is also known as mitogen-activated protein kinase 3 (MAPK3). ERK1 is part of a signal transduction pathway that begins with the small GTPase Ras and continues through a cascade of protein kinases that include Raf and MEK. Activation of this signaling pathway influences many cellular processes such as proliferation, differentiation and survival. ERK1 is very similar in sequence to ERK2/p42 and the activities of both ERK1 and ERK2 are usually considered together as total ERK activity. More recent evidence has shown that ERK1 and ERK2 are not functionally redundant and may have very different and specific roles. Alternate names for ERK1 include p44-MAPK, ERT2, p44-ERK1, MAPK 1, microtubule-associated protein kinase 2, and PRKM3.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00505 maps to a region between residue 329 and 379 of human extracellular signal-related kinase 1 (mitogen-activated protein kinase 3) using the numbering given in entry NP_002737.2 (GeneID 5595).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A302-019A
IP Erklärungen der Abkürzungen ansehen.
Shc1 (src-homology domain protein C1) was originally identified as an SH2 containing proto-oncogene involved in growth factor signaling. Shc1 is functions as a signaling adapter that couples activated growth factor receptors to signaling pathways. Shc1 is also known as Shc, and ShcA.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A302-019A maps to a region between residue 300 and 350 of human SHC (Src homology 2 domain containing) transforming protein 1 using the numbering given in entry NP_892113.4 (GeneID 6464).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A302-020A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Shc1 (src-homology domain protein C1) was originally identified as an SH2 containing proto-oncogene involved in growth factor signaling. Shc1 is functions as a signaling adapter that couples activated growth factor receptors to signaling pathways. Shc1 is also known as Shc, and ShcA.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A302-020A maps to a region between residue 359 and 409 of human SHC (Src homology 2 domain containing) transforming protein 1 using the numbering given in entry NP_892113.4 (GeneID 6464).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-712A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A302-019A and A302-020A

Rabbit IgG SR: human
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

IHC-00587
IHC Erklärungen der Abkürzungen ansehen.
Shc1 (src-homology domain protein C1) was originally identified as an SH2 containing proto-oncogene involved in growth factor signaling. Shc1 is functions as a signaling adapter that couples activated growth factor receptors to signaling pathways. Shc1 is also known as Shc, and ShcA.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00587 maps to a region between residue 359 and 409 of human SHC (Src homology 2 domain containing) transforming protein 1 using the numbering given in entry NP_892113.4 (GeneID 6464).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A302-861A
related products

WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human
Immunogen: Synthetic peptide. The epitope recognized by A302-861A maps to a region between residue 50 and 100 of human Complement component 1, q Subcomponent Binding Protein using the numbering given in entry NP_001203.1 (GeneID 708).
Bethyl
Icon Datasheet
20 µg

Buy Bulk

349 €

A302-862A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human, mouse
Immunogen: Synthetic peptide. The epitope recognized by A302-862A maps to a region between residue 150 and 200 of human Complement component 1,q Subcomponent Binding Protein using the numbering given in entry NP_001203.1 (GeneID 708).
Bethyl
Icon Datasheet
100 µg

Buy Bulk

349 €

A302-863A
related products

WB Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human, mouse
Immunogen: Synthetic peptide. The epitope recognized by A302-863A maps to a region between residue 232 and 282 of human Complement component 1,q Subcomponent Binding Protein using the numbering given in entry NP_001203.1 (GeneID 708).
Bethyl
Icon Datasheet
100 µg

Buy Bulk

349 €

A311-055A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Rabbit IgG SR: human, mouse
Bethyl
Icon Datasheet
1 Stck

Buy Bulk

729 €

A304-234A
WB, IP Erklärungen der Abkürzungen ansehen.
Protein function: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A304-234A maps to a region between residue 311 to 361 of human Hydroxymethylbilane Synthase using the numbering given in entry NP_000181.2 (GeneID 3145).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A302-752A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
STAT1 (signal transducer and activator of transcription 1) is a member of the STAT protein family). In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT1 can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Alternative names for STAT1 include ISGF-3, STAT91, signal transducer and activator of transcription 1-alpha/beta, and Transcription factor ISGF-3 components p91/p84. [taken from NCBI Entrez Gene (GeneID: 6772)]

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A302-752A maps to a region between residue 175 and 225 of human Signal Transducer and Activator of Transcription 1 using the numbering given in entry NP_009330.1 (GeneID 6772).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A302-753A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
STAT1 (signal transducer and activator of transcription 1) is a member of the STAT protein family). In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT1 can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Alternative names for STAT1 include ISGF-3, STAT91, signal transducer and activator of transcription 1-alpha/beta, and Transcription factor ISGF-3 components p91/p84. [taken from NCBI Entrez Gene (GeneID: 6772)]

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A302-753A maps to a region between residue 700 and 750 of human Signal Transducer and Activator of Transcription 1 using the numbering given in entry NP_009330.1 (GeneID 6772).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A311-007A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A302-752A and A302-753A

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A303-883A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
ADAR1 (adenosine deaminase, RNA specific) is an enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditary [taken from NCBI Entrez Gene (Gene ID: 103)].

Rabbit IgG SR: human
Immunogen: Synthetic peptide. The epitope recognized by A303-883A maps to a region between residue 200 and 250 of human Adenosine Deaminase, RNA-specific using the numbering given in entry NP_001102.2 (GeneID 103).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-884A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
ADAR1 (adenosine deaminase, RNA specific) is an enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditary [taken from NCBI Entrez Gene (Gene ID: 103)].

Rabbit IgG SR: human
Immunogen: Synthetic peptide. The epitope recognized by A303-884A maps to a region between residue 950 and 1000 of human Adenosine Deaminase, RNA-specific using the numbering given in entry NP_001102.2 (GeneID 103).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A311-420A
WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A303-883A and A303-884A

Rabbit IgG SR: human
Immunogen: Synthetic peptide. Antibodies were affinity purified using epitopes specific to ADAR1 immobilized on solid support.
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A300-086A
related products

WB, IP, IHC, ChIP, FC Erklärungen der Abkürzungen ansehen.
MLL1 (mixed lineage leukemia 1) has been found to participate in a multitude of chromosomal translocations that are associated with a variety of hematologic malignancies. MLL1 functions as a transcriptional regulator and plays and important role in HOX gene expression during embryonic development. Alternate names for MLL1 include zinc-finger protein HRX, ALL-1, trithorax-like protein, MLL, ALL1, HRX, HTRX1, THRX, TRX1, CXXC7, MLL1A, FLJ11783, and MLL/GAS7.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-086A maps to a region between residues 720 and 780 of human myeloid/lymphoid or mixed-lineage leukemia 1 using the number given in Swiss-Prot entry Q03164 (GeneID 4297).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

417 €

A300-087A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
MLL1 (mixed lineage leukemia 1) has been found to participate in a multitude of chromosomal translocations that are associated with a variety of hematologic malignancies. MLL1 functions as a transcriptional regulator and plays and important role in HOX gene expression during embryonic development. Alternate names for MLL1 include zinc-finger protein HRX, ALL-1, trithorax-like protein, MLL, ALL1, HRX, HTRX1, THRX, TRX1, CXXC7, MLL1A, FLJ11783, and MLL/GAS7.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-087A maps to a region between residues 1320 and 1380 of human myeloid/lymphoid or mixed-lineage leukemia 1 using the number given in Swiss-Prot entry Q03164 (GeneID 4297).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

417 €

A300-374A
related products

WB, IP, ChIP Erklärungen der Abkürzungen ansehen.
MLL1 (mixed lineage leukemia 1) has been found to participate in a multitude of chromosomal translocations that are associated with a variety of hematologic malignancies. MLL1 functions as a transcriptional regulator and plays and important role in HOX gene expression during embryonic development. Alternate names for MLL1 include zinc-finger protein HRX, ALL-1, trithorax-like protein, MLL, ALL1, HRX, HTRX1, THRX, TRX1, CXXC7, MLL1A, FLJ11783, and MLL/GAS7.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-374A maps to a region between residues 2725 and 2775 of human myeloid/lymphoid or mixed-lineage leukemia 1 using the number given in Swiss-Prot entry Q03164 (GeneID 4297).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-375A
related products

WB Erklärungen der Abkürzungen ansehen.
MLL1 (mixed lineage leukemia 1) has been found to participate in a multitude of chromosomal translocations that are associated with a variety of hematologic malignancies. MLL1 functions as a transcriptional regulator and plays and important role in HOX gene expression during embryonic development. Alternate names for MLL1 include zinc-finger protein HRX, ALL-1, trithorax-like protein, MLL, ALL1, HRX, HTRX1, THRX, TRX1, CXXC7, MLL1A, FLJ11783, and MLL/GAS7.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-375A maps to a region between residue 3900 and the C-terminus (residue 3969) of human myeloid/lymphoid or mixed-lineage leukemia 1 using the number given in Swiss-Prot entry Q03164 (GeneID 4297).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-023A
related products

WB, IP, IHC Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to MLL1 immobilized on solid support.

Rabbit IgG SR: human, mouse
Bethyl
Icon Datasheet
1 pack

Buy Bulk

966 €

A304-196A
IP Erklärungen der Abkürzungen ansehen.
Protein function: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys- 27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1, CDKN2A and retinoic acid target genes. EZH2 can also methylate non-histone proteins such as the transcription factor GATA4 and the nuclear receptor RORA. [The UniProt Consortium]

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A304-196A maps to a region between residue 175 to 225 of human Enhancer of Zeste Homolog 2 using the numbering given in entry CAA64955.1 (GeneID 2146).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A304-197A
WB, IP Erklärungen der Abkürzungen ansehen.
Protein function: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys- 27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1, CDKN2A and retinoic acid target genes. EZH2 can also methylate non-histone proteins such as the transcription factor GATA4 and the nuclear receptor RORA. [The UniProt Consortium]

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A304-197A maps to a region between residue 696 to 746 of human Enhancer of Zeste Homolog 2 using the numbering given in entry CAA64955.1 (GeneID 2146).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A311-507A
WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A304-196A and A304-197A

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. Antibodies were affinity purified using epitopes specific to EZH2 immobilized on solid support.
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

IHC-00388
IHC, IHC-​IF Erklärungen der Abkürzungen ansehen.
EZH2 is a polycomb group enzyme that functions to methylate histone H3-lysine 27 and mediate gene silencing of Homeobox (Hox) genes during development. EZH2 possesses a SET domain which is important to methyltransferase activity. Amplification of EZH2 has been reported in a number of malignancies and may contribute to oncogenesis. Alternate names for EZH2 include enhancer of zeste homolog 2, ENX-1, and MGC9169.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by IHC-00388 maps to phosphorylated Serine 21 and surrounding residues of human Enhancer of Zeste homolog 2 using the numbering given in entry NP_004447.2 (GeneID 2146).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

429 €

A302-337A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. Alternative names for c-Cbl include Casitas B-lineage lymphoma proto-oncogene, Cas-Br-M ectropic retroviral transforming sequence, RING finger protein 55, proto-oncogene c-CBL, CBL2, and RNF55.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A302-337A maps to a region between residue 575 and 625 of human Casitas B-lineage lymphoma proto-oncogene using the numbering given in entry NP_005179.2 (GeneID 867).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A302-338A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. Alternative names for c-Cbl include Casitas B-lineage lymphoma proto-oncogene, Cas-Br-M ectropic retroviral transforming sequence, RING finger protein 55, proto-oncogene c-CBL, CBL2, and RNF55.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A302-338A maps to a region between residue 675 and 725 of human Casitas B-lineage lymphoma proto-oncogene using the numbering given in entry NP_005179.2 (GeneID 867).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-847A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A302-337A and A302-338A

Rabbit IgG SR: human
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A301-399A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
HCF1 was originally identified as a host-cell factor utilized by the herpes simplex virus to promote viral transcription. In the cell, HCF1 functions as a transcriptional co-regulator involved in the modification of histones and cell cycle progression. Alternate names for HCF1 include host cell factor, HCF, HCFC1, C1 factor, VP16 accessory protein, HFC1, HCF-1, and VCAF.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-399A maps to a region between residue 1700 and 1750 of human host cell factor C1 (VP16-accessory protein) using the numbering given in entry NP_005325.2 (GeneID 3054).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-400A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
HCF1 was originally identified as a host-cell factor utilized by the herpes simplex virus to promote viral transcription. In the cell, HCF1 functions as a transcriptional co-regulator involved in the modification of histones and cell cycle progression. Alternate names for HCF1 include host cell factor, HCF, HCFC1, C1 factor, VP16 accessory protein, HFC1, HCF-1, and VCAF.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-400A maps to a region between residue 1985 and 2035 of human host cell factor C1 (VP16-accessory protein) using the numbering given in entry NP_005325.2 (GeneID 3054).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-484A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A301-399A and A301-400A

Rabbit IgG SR: human
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A300-822A
IP Erklärungen der Abkürzungen ansehen.
Histone H3 is one of four histone proteins that assemble into an octamer to form the nucleosome core and serve to spool and compact DNA into chromatin. Histones are subject to a complex set of post-translational modifications (acetylation, methylation, phosphorylation, ubiquitination, sumoylation, citrullination, and ADP ribosylation) that are important to the regulation of gene transcription, DNA replication, and DNA repair.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-822A maps to a region between residue 1 and 50 of human Histone H3 using the numbering given in entry NP_003520.1 (GeneID 8350).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-823A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
Histone H3 is one of four histone proteins that assemble into an octamer to form the nucleosome core and serve to spool and compact DNA into chromatin. Histones are subject to a complex set of post-translational modifications (acetylation, methylation, phosphorylation, ubiquitination, sumoylation, citrullination, and ADP ribosylation) that are important to the regulation of gene transcription, DNA replication, and DNA repair.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-823A maps to a region between residue 100 and the C-terminus (residue 135) of human Histone H3 using the numbering given in entry NP_003520.1 (GeneID 8350).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-844A
related products

WB, FC Erklärungen der Abkürzungen ansehen.
Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.

Rabbit IgG SR: human
Immunogen: synthetic phospho-peptide. Immunogen for A301-844A was a synthetic phosphorylated peptide, which represented a portion of human Histone H3 surrounding serine 10 according to the numbering given in entry NP_003520.1 (GeneID 8350).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

373 €

A310-257A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to Histone H3 immobilized on solid support.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

E300-001B
related products

ELISA Erklärungen der Abkürzungen ansehen.
Extra supply of antibody to be used with the Histone H3 PathProfiler ELISA kit (#E300-001).

Rabbit IgG
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
manual
1 vial

Buy Bulk

111 €

IHC-00061
related products

IHC, ICC, FC Erklärungen der Abkürzungen ansehen.
Histone H3 is one of four histone proteins that assemble into an octamer to form the nucleosome core and serve to spool and compact DNA into chromatin. Histones are subject to a complex set of post-translational modifications (acetylation, methylation, phosphorylation, ubiquitination, sumoylation, citrullination, and ADP ribosylation) that are important to the regulation of gene transcription, DNA replication, and DNA repair.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. Immunogen for IHC-00061 was a synthetic phosphorylated peptide, which represented a portion of human Histone H3 surrounding Serine 10 according to the numbering given in entry NP_003520.1 (GeneID 8350).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

429 €

IHC-00465
IHC Erklärungen der Abkürzungen ansehen.
Histone H3 is one of four histone proteins that assemble into an octamer to form the nucleosome core and serve to spool and compact DNA into chromatin. Histones are subject to a complex set of post-translational modifications (acetylation, methylation, phosphorylation, ubiquitination, sumoylation, citrullination, and ADP ribosylation) that are important to the regulation of gene transcription, DNA replication, and DNA repair.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by IHC-00465 maps to a region between residue 100 and the C-terminus (residue 135) of human Histone H3 using the numbering given in entry NP_003520.1 (GeneID 8350).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A304-226A
WB, IP Erklärungen der Abkürzungen ansehen.
Protein tyrosine kinase 2 (PYK2) is a non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. PYK2 plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. It is required for normal macrophage polarization and migration towards sites of inflammation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q14289].

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A304-226A maps to a region between residue 275 to 325 of human Protein Tyrosine Kinase 2 beta using the numbering given in entry NP_775266.1 (GeneID 2185).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A304-227A
WB, IP Erklärungen der Abkürzungen ansehen.
Protein tyrosine kinase 2 (PYK2) is a non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. PYK2 plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. It is required for normal macrophage polarization and migration towards sites of inflammation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q14289].

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A304-227A maps to a region between residue 959 to 1009 of human Protein Tyrosine Kinase 2 beta using the numbering given in entry NP_775266.1 (GeneID 2185).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A311-519A
WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A304-226A and A304-227A

Rabbit IgG SR: human
Immunogen: synthetic peptide. Antibodies were affinity purified using epitopes specific to PYK2 immobilized on solid support.
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A303-735A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells [taken from NCBI Entrez Gene (Gene ID: 3688)].

Rabbit IgG SR: human
Immunogen: Synthetic peptide. The epitope recognized by A303-735A maps to a region between residue 650 and 700 of human Integrin, Beta 1 using the numbering given in entry NP_002202.2 (GeneID 3688).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-133A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Specificity protein 1 (Sp1) is the original member of the Sp1-like/KLF family of zinc-finger transcription factors that binds GC-rich DNA elements to regulate transcription of genes involved in a variety of cellular functions. Sp-1 interacts with coactivators such as p300/CBP, TAFII130, and CRSP.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-133A maps to a region between residues 700 and 740 using the numbering given in entry XP_028606.4 (GeneID 6667).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-134A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
Specificity protein 1 (Sp1) is the original member of the Sp1-like/KLF family of zinc-finger transcription factors that binds GC-rich DNA elements to regulate transcription of genes involved in a variety of cellular functions. Sp-1 interacts with coactivators such as p300/CBP, TAFII130, and CRSP.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-134A maps to a region between residue 750 and the C-terminus (residue 785) using the numbering given in entry XP_028606.4 (GeneID 6667).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-944A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Specificity protein 1 (Sp1) is the original member of the Sp1-like/KLF family of zinc-finger transcription factors that binds GC-rich DNA elements to regulate transcription of genes involved in a variety of cellular functions. Sp-1 interacts with coactivators such as p300/CBP, TAFII130, and CRSP.

Goat IgG SR: human, mouse
Immunogen: Synthetic peptide. The epitope recognized by A303-944A maps to a region between residue 735 to 785 of human Sp1 Transcription Factor using the numbering given in entry NP_612482.2 (GeneID 6667).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-033A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to Sp1 immobilized on solid support.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

IHC-00208
IHC Erklärungen der Abkürzungen ansehen.
Specificity protein 1 (Sp1) is the original member of the Sp1-like/KLF family of zinc-finger transcription factors that binds GC-rich DNA elements to regulate transcription of genes involved in a variety of cellular functions. Sp-1 interacts with coactivators such as p300/CBP, TAFII130, and CRSP.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00208 maps to a region between residues 750 and the C-terminus (residue 785) of human Sp1 using the numbering given in entry XP_028606.4 (GeneID 6667).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A302-545A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
RACK1 (receptor of activated protein kinase C1) was originally identified as a factor that could bind the activated form of protein kinase C. It contains seven WD40 motifs that interact with various signaling molecules. Alternative names for RACK1 include guanine nucleotide-binding protein subunit beta-2-like 1, GNB2L1, cell proliferation-inducing gene 21 protein, PIG21, human lung cancer oncogene 7 protein, HLC-7, and Gnb2-rs1.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A302-545A maps to a region between residue 1 and 50 of human receptor of activated protein kinase C 1 using the numbering given in entry NP_006089.1 (GeneID 10399).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-663A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Cyclin-dependent kinase 1 (CDK1) is a member of the Ser/Thr protein kinase family. CDK1 is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of CKD1 is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternative names for CDK1 include cell division control protein 2 homolog, cell division protein kinase 1, p34 protein kinase, CDC2, CDC28A, CDKN1, and P34CDC2. [taken from NCBI Entrez Gene (Gene ID: 983)]

Rabbit IgG SR: human
Immunogen: Synthetic peptide. The epitope recognized by A303-663A maps to a region between residue 1 and 50 of human Cyclin-Dependent Kinase 1 using the numbering given in entry NP_001777.1 (GeneID 983).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-664A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Cyclin-dependent kinase 1 (CDK1) is a member of the Ser/Thr protein kinase family. CDK1 is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of CKD1 is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternative names for CDK1 include cell division control protein 2 homolog, cell division protein kinase 1, p34 protein kinase, CDC2, CDC28A, CDKN1, and P34CDC2. [taken from NCBI Entrez Gene (Gene ID: 983)]

Rabbit IgG SR: human
Immunogen: Synthetic peptide. The epitope recognized by A303-664A maps to a region between residue 225 and 275 of human Cyclin-Dependent Kinase 1 using the numbering given in entry NP_001777.1 (GeneID 983).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A311-344A
WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A303-663A and A303-664A

Rabbit IgG SR: human
Immunogen: Synthetic peptide. Antibodies were affinity purified using epitopes specific to CDK1 immobilized on solid support.
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A300-404A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Glucose-6-phosphate dehydrogenase (G6PD) is a cytosolic enzyme that catalyzes the conversion of glucose-6-phosphate into 6-phosphgluconolactone and maintains the levels of the electron donor, NADPH. G6PD is an x-linked housekeeping gene whose deficiency can result in neonatal jaundice, acute hemolysis, or chronic non-spherocytic hemolytic anemia.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-404A maps to a region between residues 50 and 100 of human Glucose-6-Phosphate Dehydrogenase using the numbering given in entry NP_000393.2 (GeneID 2539).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

IHC-00007
IHC Erklärungen der Abkürzungen ansehen.
Glucose-6-phosphate dehydrogenase (G6PD) is a cytosolic enzyme that catalyzes the conversion of glucose-6-phosphate into 6-phosphgluconolactone and maintains the levels of the electron donor, NADPH. G6PD is an x-linked housekeeping gene whose deficiency can result in neonatal jaundice, acute hemolysis, or chronic non-spherocytic hemolytic anemia.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by IHC-00007 maps to a region between residues 50 and 100 of human Glucose-6-Phosphate Dehydrogenase using the numbering given in entry NP_000393.2 (GeneID 2539).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

S300-404
IP Erklärungen der Abkürzungen ansehen.
Rabbit anti-human G6PD affinity purified Antibodies were coupled to agarose beads using a cyanogen bromide method.

Rabbit IgG SR: human, mouse
Bethyl
Icon Datasheet
100 µg

Buy Bulk

367 €

A300-276A
related products

WB, IP, FC, PLA Erklärungen der Abkürzungen ansehen.
PCNA (Proliferating Cell Nuclear Antigen) was first identified as a factor expressed in the nuclei of replicating cells. PCNA plays a role in both DNA synthesis and repair. PCNA functions as a processivity factor for DNA polymerase by acting as a DNA clamp that tethers the polymerase catalytic units to the DNA template. The structure of PCNA is that of a trimeric ring that encircles and slides along replicating DNA. PCNA interacts with and is regulated by several proteins involved in cell cycle control and check point processes.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-276A maps to a region between residues 75 and 125 of human proliferating cell nuclear antigen using the numbering given in SwissProt entry P12004 (GeneID 5111).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-276B
related products

WB, IP, FC Erklärungen der Abkürzungen ansehen.
PCNA (Proliferating Cell Nuclear Antigen) was first identified as a factor expressed in the nuclei of replicating cells. PCNA plays a role in both DNA synthesis and repair. PCNA functions as a processivity factor for DNA polymerase by acting as a DNA clamp that tethers the polymerase catalytic units to the DNA template. The structure of PCNA is that of a trimeric ring that encircles and slides along replicating DNA. PCNA interacts with and is regulated by several proteins involved in cell cycle control and check point processes.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-276B maps to a region between residues 75 and 125 of human proliferating cell nuclear antigen using the numbering given in SwissProt entry P12004 (GeneID 5111).
Bethyl
Icon Datasheet
100 µg

Buy Bulk

374 €

A300-277A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
PCNA (Proliferating Cell Nuclear Antigen) was first identified as a factor expressed in the nuclei of replicating cells. PCNA plays a role in both DNA synthesis and repair. PCNA functions as a processivity factor for DNA polymerase by acting as a DNA clamp that tethers the polymerase catalytic units to the DNA template. The structure of PCNA is that of a trimeric ring that encircles and slides along replicating DNA. PCNA interacts with and is regulated by several proteins involved in cell cycle control and check point processes.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-276A maps to a region between residue 225 and the C-terminus (residue 261) of human proliferating cell nuclear antigen using the numbering given in SwissProt entry P12004 (GeneID 5111).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-277B
related products

WB, IP Erklärungen der Abkürzungen ansehen.
PCNA (Proliferating Cell Nuclear Antigen) was first identified as a factor expressed in the nuclei of replicating cells. PCNA plays a role in both DNA synthesis and repair. PCNA functions as a processivity factor for DNA polymerase by acting as a DNA clamp that tethers the polymerase catalytic units to the DNA template. The structure of PCNA is that of a trimeric ring that encircles and slides along replicating DNA. PCNA interacts with and is regulated by several proteins involved in cell cycle control and check point processes.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-277B maps to a region between residue 225 and the C-terminus (residue 261) of human proliferating cell nuclear antigen using the numbering given in SwissProt entry P12004 (GeneID 5111).
Bethyl
Icon Datasheet
100 µg

Buy Bulk

374 €

A310-076A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to PCNA immobilized on solid support.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

IHC-00012
IHC Erklärungen der Abkürzungen ansehen.
PCNA (Proliferating Cell Nuclear Antigen) was first identified as a factor expressed in the nuclei of replicating cells. PCNA plays a role in both DNA synthesis and repair. PCNA functions as a processivity factor for DNA polymerase by acting as a DNA clamp that tethers the polymerase catalytic units to the DNA template. The structure of PCNA is that of a trimeric ring that encircles and slides along replicating DNA. PCNA interacts with and is regulated by several proteins involved in cell cycle control and check point processes.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by IHC-00012 maps to a region between residue 225 and the C-terminus (residue 261) of human proliferating cell nuclear antigen using the numbering given in entry NP 002583.1 (GeneID 5111).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

IHC-00219
IHC Erklärungen der Abkürzungen ansehen.
PCNA (Proliferating Cell Nuclear Antigen) was first identified as a factor expressed in the nuclei of replicating cells. PCNA plays a role in both DNA synthesis and repair. PCNA functions as a processivity factor for DNA polymerase by acting as a DNA clamp that tethers the polymerase catalytic units to the DNA template. The structure of PCNA is that of a trimeric ring that encircles and slides along replicating DNA. PCNA interacts with and is regulated by several proteins involved in cell cycle control and check point processes.

Rabbit IgG SR: human
Immunogen: synthetic peptide. Immunogen for IHC-00219 was a phosphorylated synthetic peptide, which represented a portion of human proliferating cell nuclear antigen (GeneID 5111) around tyrosine 211 according to the numbering given inentry NP_002583.1.
Bethyl
Icon Datasheet
100 µl

Buy Bulk

429 €

A300-137A
related products

WB Erklärungen der Abkürzungen ansehen.
ATR (ATM and Rad3 related) is closely related to ATM (Ataxia telangiectasia, mutated) and is a member of the phosphatidylinositol 3 kinase (PI-3) family that is an early sensor of DNA damage. ATR is a serine-threonine kinase that reacts to UV damage and interruptions in replication. ATR may be able to sense DNA damage through interaction with Rad17 and 1as well as components of nucleosome remodeling complexes. In response to DNA damage, ATR has been shown to phosphorylate a multitude of substrates which include BRCA1, p53, Chk2, Rad 17, and E2F transcription factor 1. ATR is also known as serine/threonine-protein kinase ATR, FRAP-related protein 1, FRP1, MEC1, SCKL, and SCKL1.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-137A maps to a region between residues 400 and 450 of human Ataxia Telangiectasia and Rad3-related using the numbering given in entry NP_001175.1 (GeneID 545).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-138A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
ATR (ATM and Rad3 related) is closely related to ATM (Ataxia telangiectasia, mutated) and is a member of the phosphatidylinositol 3 kinase (PI-3) family that is an early sensor of DNA damage. ATR is a serine-threonine kinase that reacts to UV damage and interruptions in replication. ATR may be able to sense DNA damage through interaction with Rad17 and 1as well as components of nucleosome remodeling complexes. In response to DNA damage, ATR has been shown to phosphorylate a multitude of substrates which include BRCA1, p53, Chk2, Rad 17, and E2F transcription factor 1. ATR is also known as serine/threonine-protein kinase ATR, FRAP-related protein 1, FRP1, MEC1, SCKL, and SCKL1.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-138A maps to a region between residues 1675 and 1725 of human Ataxia Telangiectasia and Rad3-related using the numbering given in entry NP_001175.1 (GeneID 545).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-035A
related products

WB Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to ATR immobilized on solid support.

Rabbit IgG SR: human, mouse
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

S300-137
IP Erklärungen der Abkürzungen ansehen.
Rabbit anti-ATR affinity purified antibodies were coupled to agarose beads using a cyanogen bromide method.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
100 µg

Buy Bulk

367 €

A300-431A
related products

WB, IP, IF Erklärungen der Abkürzungen ansehen.
Aurora B is the central enzymatic unit of the chromosomal passenger complex (CPC). In the CPC, Aurora B is associated with the passenger proteins inner centromeric protein (INCENP), survivin, and borealin. Aurora B is a serine-threonine protein kinase essential for chromosome segregation and cytokinesis. Specific roles for Aurora B have been demonstrated in cohesin dissociation from centromeres as well as condensin I binding to chromatin. Substrates of Aurora B kinase activity include desmin, septin 1, INCENP, RAC GTPase activating protein 1, and centromeric protein A. Alternate designations for Aurora B include serine/threonine-protein kinase 12, Aurora-and lpl1-like midbody-associated protein 1, AIM-1, Aurora/IPL1-related kinase 2, Aurora-related kinase 2, STK-1, AURKB, AIK2, AIM2, ARK2, and STK12.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-431A maps to a region between residue 300 and the C-terminus (residue 344) of human Aurora B kinase using the numbering given in Swiss-Prot entry Q96GD4 (GeneID 9212).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

IHC-00003
IHC, ICC Erklärungen der Abkürzungen ansehen.
Aurora B is the central enzymatic unit of the chromosomal passenger complex (CPC). In the CPC, Aurora B is associated with the passenger proteins inner centromeric protein (INCENP), survivin, and borealin. Aurora B is a serine-threonine protein kinase essential for chromosome segregation and cytokinesis. Specific roles for Aurora B have been demonstrated in cohesin dissociation from centromeres as well as condensin I binding to chromatin. Substrates of Aurora B kinase activity include desmin, septin 1, INCENP, RAC GTPase activating protein 1, and centromeric protein A. Alternate designations for Aurora B include serine/threonine-protein kinase 12, Aurora-and lpl1-like midbody-associated protein 1, AIM-1, Aurora/IPL1-related kinase 2, Aurora-related kinase 2, STK-1, AURKB, AIK2, AIM2, ARK2, and STK12.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00003 maps to a region between residue 300 and the C-terminus (residue 344) of human Aurora B Kinase using the numbering given in SwissProt entry Q96GD4 (GeneID 9212).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A301-352A
related products

WB Erklärungen der Abkürzungen ansehen.
Death-associated protein (DAXX) is a multifunctional protein originally identified as a FAS-interacting protein that modulates FAS-induced cell death. The involvement of DAXX in apoptosis has been difficult to understand, and its exact function in this process has only partially been elucidated. DAXX appears to also function as a transcriptional co-repressor and has been found to associate with the SNF2 chromatin-remodeling ATPase, alpha-thalassemia syndrome protein (ATRX), and modulate transcription. Alternate names for DAXX include death domain-associated protein 6, Fas death domain-associated protein, ETS1-associated protein 1, EAP1, BING2, and DAP6.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-352A maps to a region between residue 400 and 450 of human death-associated protein 6 using the numbering given in entry NP_001341.1 (GeneID 1616).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-353A
related products

WB, PLA Erklärungen der Abkürzungen ansehen.
Death-associated protein (DAXX) is a multifunctional protein originally identified as a FAS-interacting protein that modulates FAS-induced cell death. The involvement of DAXX in apoptosis has been difficult to understand, and its exact function in this process has only partially been elucidated. DAXX appears to also function as a transcriptional co-repressor and has been found to associate with the SNF2 chromatin-remodeling ATPase, alpha-thalassemia syndrome protein (ATRX), and modulate transcription. Alternate names for DAXX include death domain-associated protein 6, Fas death domain-associated protein, ETS1-associated protein 1, EAP1, BING2, and DAP6.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-353A maps to a region between residue 466 and 516 of human death-associated protein 6 using the numbering given in entry NP_001341.1 (GeneID 1616).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-466A
related products

WB Erklärungen der Abkürzungen ansehen.
1 each of A301-352A and A301-353A

Rabbit IgG SR: human
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A301-620A
related products

WB, PLA Erklärungen der Abkürzungen ansehen.
Vimentin is an intermediate filament expressed mainly in mesenchymal tissue and in primitive (undifferentiated) non-mesenchymal cells. It is a Class III cytoplasmic filament that forms a dense cytoskeletal network that extends from the nucleus to the plasma membrane. Vimentin reorganization during mitosis is likely regulated via its multiple phosphorylation sites. Vimentin expression is also found in mesoderm derived epithelia. Immunohistochemistry (IHC) with anti-vimentin antibodies is often used to identify neoplasms of mesenchymal or mesodermal origin.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A301-620A maps to a region between residue 416 and 466 of human vimentin using the numbering given in entry NP_003371.2 (GeneID 7431).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

IHC-00314
IHC, IHC-​IF Erklärungen der Abkürzungen ansehen.
Vimentin is an intermediate filament expressed mainly in mesenchymal tissue and in primitive (undifferentiated) non-mesenchymal cells. It is a Class III cytoplasmic filament that forms a dense cytoskeletal network that extends from the nucleus to the plasma membrane. Vimentin reorganization during mitosis is likely regulated via its multiple phosphorylation sites. Vimentin expression is also found in mesoderm derived epithelia. Immunohistochemistry (IHC) with anti-vimentin antibodies is often used to identify neoplasms of mesenchymal or mesodermal origin.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00314 maps to a region between residue 416 and 466 of human vimentin using the numbering given in entry NP_003371.2 (GeneID 7431).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A301-375A
related products

WB, PLA Erklärungen der Abkürzungen ansehen.
PARP1 (Poly-ADP-ribose polymerase 1) is a member of PARP family of enzymes that transfer the ADP-D-ribosyl group of NAD(plus) to an acceptor carboxyl group on proteins. PARP1 catalyzes the poly-ADP-ribosylation of histone and non-histone proteins in response to DNA damage. The over-activation of PARP-1 in response to DNA damage has been shown to promote cell and tissue injury. This observation has initiated research into the therapeutic potential of PARP1 inhibitors in the treatment of cancer, cardiovascular disease, and brain injury. Alternate names for PARP1 include ADPRT, NAD(plus) ADP-ribosyltransferase 1, poly-ADP-ribose synthase 1, ADPRT, PPOL, PARP, PARP-1, and pADPRT-1.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-375A maps to a region between residue 1 and 50 of human poly (ADP-ribose) polymerase family, member 1 using the numbering given in entry NP_001609.1 (GeneID 142).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-376A
related products

WB Erklärungen der Abkürzungen ansehen.
PARP1 (Poly-ADP-ribose polymerase 1) is a member of PARP family of enzymes that transfer the ADP-D-ribosyl group of NAD(plus) to an acceptor carboxyl group on proteins. PARP1 catalyzes the poly-ADP-ribosylation of histone and non-histone proteins in response to DNA damage. The over-activation of PARP-1 in response to DNA damage has been shown to promote cell and tissue injury. This observation has initiated research into the therapeutic potential of PARP1 inhibitors in the treatment of cancer, cardiovascular disease, and brain injury. Alternate names for PARP1 include ADPRT, NAD(plus) ADP-ribosyltransferase 1, poly-ADP-ribose synthase 1, ADPRT, PPOL, PARP, PARP-1, and pADPRT-1.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-376A maps to a region between residue 50 and 100 of human poly (ADP-ribose) polymerase family, member 1 using the numbering given in entry NP_001609.1 (GeneID 142).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-476A
related products

WB Erklärungen der Abkürzungen ansehen.
1 each of A301-375A and A301-376A

Rabbit IgG SR: human
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

IHC-00279
IHC Erklärungen der Abkürzungen ansehen.
PARP1 (Poly-ADP-ribose polymerase 1) is a member of PARP family of enzymes that transfer the ADP-D-ribosyl group of NAD(plus) to an acceptor carboxyl group on proteins. PARP1 catalyzes the poly-ADP-ribosylation of histone and non-histone proteins in response to DNA damage. The over-activation of PARP-1 in response to DNA damage has been shown to promote cell and tissue injury. This observation has initiated research into the therapeutic potential of PARP1 inhibitors in the treatment of cancer, cardiovascular disease, and brain injury. Alternate names for PARP1 include ADPRT, NAD(plus) ADP-ribosyltransferase 1, poly-ADP-ribose synthase 1, ADPRT, PPOL, PARP, PARP-1, and pADPRT-1.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00279 maps to a region between residue 50 and 100 of human poly (ADP-ribose) polymerase family, member 1 using the numbering given in entry NP_001609.1 (GeneID 142).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A301-121A
IP Erklärungen der Abkürzungen ansehen.
Defects in XPC are a cause of xeroderma pigmentosum complementation group C, a rare autosomal recessive diseased characterized by hypersensitivity to sunlight and an elevated risk of skin cancer on sun-exposed areas. XPC is involved in nucleotide excision repair and performs its function as part of a heterodimeric complex with HHR23B. XPC has been found to play a role in the early stages of repair that involve incising damaged DNA. Alternate names for XPC include DNA-repair protein complementing XP-C cells, xeroderma pigmentosum group C-complementing protein, p125, XPCC, and XP3.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-121A maps to a region between residue 825 and 875 of human xeroderma pigmentosum, complementation group C using the numbering given in entry NP_004619.2 (GeneID 7508).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-122A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Defects in XPC are a cause of xeroderma pigmentosum complementation group C, a rare autosomal recessive diseased characterized by hypersensitivity to sunlight and an elevated risk of skin cancer on sun-exposed areas. XPC is involved in nucleotide excision repair and performs its function as part of a heterodimeric complex with HHR23B. XPC has been found to play a role in the early stages of repair that involve incising damaged DNA. Alternate names for XPC include DNA-repair protein complementing XP-C cells, xeroderma pigmentosum group C-complementing protein, p125, XPCC, and XP3.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-122A maps to a region between residue 890 and 940 of human xeroderma pigmentosum, complementation group C using the numbering given in entry NP_004619.2 (GeneID 7508).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-369A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to XPC immobilized on solid support.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A300-093A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
TBK1 is a member of the I-kappa-B kinase (IKK) family that plays a role in embryonic development and in the innate immune response. In response to viral infection, TBK1 activity induces transcription of genes such as IFN-gamma inducible protein (ip10), and interferon beta (ifnb). TBK1 is also implicated in the NF-kappa-B activation pathway which involves phosphorylation of I-kappaB proteins and the release and translocation of the NF-kappa-B complex to the nucleus. Alternate designations of TBK1 include serine/threonine-protein kinas TBK1, TANK-binding kinase, T2K, NF-kappa-B-activating kinase, NAK, and FLJ11330.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-093A maps to a region between residues 675 and the C-terminus (residue 729) of human TANK-binding kinase 1 using the numbering given in entry NP_037386.1 (GeneID 29110).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-474A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
DDX3 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX3 exhibits a variety of functions. DDX3 is a candidate tumor suppressor that suppresses tumor growth and transcriptionally activates the p21 promoter. DDX3 has been shown to play a role in translation as an eIF4E inhibitory protein that regulates translation initiation. These findings, as well as the observation that DDX3 is regulated by hepatitis C virus and is down-regulated in hepatocellular carcinoma, suggest an important role for DDX3 in growth-regulatory functions. DDX3 is also known as ATP-dependent RNA helicase DDX3X, DEAD box protein 3 X-chromosomal, helicase-like protein 2, HLP2, DEAD box X isoform, DDX3X, DBX, and DDX14.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-474A maps to a region between residues 1 and 50 of human DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 using the numbering given in entry NP_001347.2 (GeneID 1654).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-475A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
DDX3 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX3 exhibits a variety of functions. DDX3 is a candidate tumor suppressor that suppresses tumor growth and transcriptionally activates the p21 promoter. DDX3 has been shown to play a role in translation as an eIF4E inhibitory protein that regulates translation initiation. These findings, as well as the observation that DDX3 is regulated by hepatitis C virus and is down-regulated in hepatocellular carcinoma, suggest an important role for DDX3 in growth-regulatory functions. DDX3 is also known as ATP-dependent RNA helicase DDX3X, DEAD box protein 3 X-chromosomal, helicase-like protein 2, HLP2, DEAD box X isoform, DDX3X, DBX, and DDX14.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-475A maps to a region between residues 550 and 600 of human DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 using the numbering given in entry NP_001347.2 (GeneID 1654).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-476A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
DDX3 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX3 exhibits a variety of functions. DDX3 is a candidate tumor suppressor that suppresses tumor growth and transcriptionally activates the p21 promoter. DDX3 has been shown to play a role in translation as an eIF4E inhibitory protein that regulates translation initiation. These findings, as well as the observation that DDX3 is regulated by hepatitis C virus and is down-regulated in hepatocellular carcinoma, suggest an important role for DDX3 in growth-regulatory functions. DDX3 is also known as ATP-dependent RNA helicase DDX3X, DEAD box protein 3 X-chromosomal, helicase-like protein 2, HLP2, DEAD box X isoform, DDX3X, DBX, and DDX14.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-476A maps to a region between residue 600 and the C-terminus (residue 661) of human DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 using the numbering given in entry NP_001347.2 (GeneID 1654).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-136A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to DDX3 immobilized on solid support.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

729 €

IHC-00431
IHC Erklärungen der Abkürzungen ansehen.
DDX3 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX3 exhibits a variety of functions. DDX3 is a candidate tumor suppressor that suppresses tumor growth and transcriptionally activates the p21 promoter. DDX3 has been shown to play a role in translation as an eIF4E inhibitory protein that regulates translation initiation. These findings, as well as the observation that DDX3 is regulated by hepatitis C virus and is down-regulated in hepatocellular carcinoma, suggest an important role for DDX3 in growth-regulatory functions. DDX3 is also known as ATP-dependent RNA helicase DDX3X, DEAD box protein 3 X-chromosomal, helicase-like protein 2, HLP2, DEAD box X isoform, DDX3X, DBX, and DDX14.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by IHC-00431 maps to a region between residues 1 and 50 of human DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 using the numbering given in entry NP_001347.2 (GeneID 1654).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A301-915A
IP Erklärungen der Abkürzungen ansehen.
TGF-beta activated kinase 1 (TAK1) is involved in the TGF-beta signal transduction pathway. TAK1L is a TAK1-like protein identified in a screen of a fetal brain library. TAK1L mRNA was found to be predominantly expressed in blood leukocytes and ubiquitously in human adult and fetal tissues. TAK1L was also found to be highly expressed in breast, colon, and prostate carcinoma. Alternate names for TAK1L include TAKL, C21orf7, and chromosome 21 open reading frame 7.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-915A maps to a region between residue 250 and 300 of human transforming growth factor-beta-activated kinase 1 using the numbering given in entry NP_663304.1 (GeneID 6885).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-916A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
TGF-beta activated kinase 1 (TAK1) is involved in the TGF-beta signal transduction pathway. TAK1L is a TAK1-like protein identified in a screen of a fetal brain library. TAK1L mRNA was found to be predominantly expressed in blood leukocytes and ubiquitously in human adult and fetal tissues. TAK1L was also found to be highly expressed in breast, colon, and prostate carcinoma. Alternate names for TAK1L include TAKL, C21orf7, and chromosome 21 open reading frame 7.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-916A maps to a region between residue 450 and 500 of human transforming growth factor-beta-activated kinase 1 using the numbering given in entry NP_663304.1 (GeneID 6885).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-678A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A301-915A and A301-916A

Rabbit IgG SR: human
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A300-639A
related products

WB Erklärungen der Abkürzungen ansehen.
In the process of carbohydrate metabolism, GAPDH (glyceraldehydes-3-phosphate dehydrogenase) catalyzes the oxidative phosphorylation of glyceraldehydes-3-phosphate to 1,3-diphosphoglycerate in the presence of nicotinamide adenine dinucleotide (NAD) and inorganic phosphate. In addition to its role in the oxidation of glucose, GAPDH has been shown to be involved in other cellular processes such as vesicle transport, DNA repair, DNA replication, cytoskeletal modulation, and tRNA export. Alternate names for GAPDH include aging-associated gene 9 protein, G3PD, GAPD, and MGC88685.

Rabbit IgG SR: human, mouse
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-640A
related products

WB Erklärungen der Abkürzungen ansehen.
In the process of carbohydrate metabolism, GAPDH (glyceraldehydes-3-phosphate dehydrogenase) catalyzes the oxidative phosphorylation of glyceraldehydes-3-phosphate to 1,3-diphosphoglycerate in the presence of nicotinamide adenine dinucleotide (NAD) and inorganic phosphate. In addition to its role in the oxidation of glucose, GAPDH has been shown to be involved in other cellular processes such as vesicle transport, DNA repair, DNA replication, cytoskeletal modulation, and tRNA export. Alternate names for GAPDH include aging-associated gene 9 protein, G3PD, GAPD, and MGC88685.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-640A maps to a region between residues 200 and 250 of human Glyceraldehyde-3-Phosphate Dehydrogenase using the numbering given in entry NP_002037.2 (GeneID 2597).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-641A
related products

WB, PLA Erklärungen der Abkürzungen ansehen.
In the process of carbohydrate metabolism, GAPDH (glyceraldehydes-3-phosphate dehydrogenase) catalyzes the oxidative phosphorylation of glyceraldehydes-3-phosphate to 1,3-diphosphoglycerate in the presence of nicotinamide adenine dinucleotide (NAD) and inorganic phosphate. In addition to its role in the oxidation of glucose, GAPDH has been shown to be involved in other cellular processes such as vesicle transport, DNA repair, DNA replication, cytoskeletal modulation, and tRNA export. Alternate names for GAPDH include aging-associated gene 9 protein, G3PD, GAPD, and MGC88685.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-641A maps to a region between residues 250 and 300 of human Glyceraldehyde-3-Phosphate Dehydrogenase using the numbering given in entry NP_002037.2 (GeneID 2597).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-642A
related products

WB Erklärungen der Abkürzungen ansehen.
In the process of carbohydrate metabolism, GAPDH (glyceraldehydes-3-phosphate dehydrogenase) catalyzes the oxidative phosphorylation of glyceraldehydes-3-phosphate to 1,3-diphosphoglycerate in the presence of nicotinamide adenine dinucleotide (NAD) and inorganic phosphate. In addition to its role in the oxidation of glucose, GAPDH has been shown to be involved in other cellular processes such as vesicle transport, DNA repair, DNA replication, cytoskeletal modulation, and tRNA export. Alternate names for GAPDH include aging-associated gene 9 protein, G3PD, GAPD, and MGC88685.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-642A maps to a region between residues 300 and the C-terminus (residue 335) of human Glyceraldehyde-3-Phosphate Dehydrogenase using the numbering given in entry NP_002037.2 (GeneID 2597).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A303-878A
related products

WB, PLA Erklärungen der Abkürzungen ansehen.
In the process of carbohydrate metabolism, GAPDH (glyceraldehydes-3-phosphate dehydrogenase) catalyzes the oxidative phosphorylation of glyceraldehydes-3-phosphate to 1,3-diphosphoglycerate in the presence of nicotinamide adenine dinucleotide (NAD) and inorganic phosphate. In addition to its role in the oxidation of glucose, GAPDH has been shown to be involved in other cellular processes such as vesicle transport, DNA repair, DNA replication, cytoskeletal modulation, and tRNA export.

Goat IgG SR: human, mouse
Immunogen: Synthetic peptide. The epitope recognized by A303-878A maps to a region between residue 175 and 225 of human Glyceraldehyde-3-Phosphate Dehydrogenase using the numbering given in entry NP_002037.2 (GeneID 2597).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-188A
related products

WB Erklärungen der Abkürzungen ansehen.
Antibody was affinity purified using an epitope specific to GAPDH immobilized on solid support.

Rabbit IgG SR: human, mouse
Bethyl
Icon Datasheet
1 pack

Buy Bulk

1209 €

A500-005A
related products

WB Erklärungen der Abkürzungen ansehen.
In the process of carbohydrate metabolism, GAPDH (glyceraldehydes-3-phosphate dehydrogenase) catalyzes the oxidative phosphorylation of glyceraldehydes-3-phosphate to 1,3-diphosphoglycerate in the presence of nicotinamide adenine dinucleotide (NAD) and inorganic phosphate. In addition to its role in the oxidation of glucose, GAPDH has been shown to be involved in other cellular processes such as vesicle transport, DNA repair, DNA replication, cytoskeletal modulation, and tRNA export. Alternate names for GAPDH include aging-associated gene 9 protein, G3PD, GAPD, and MGC88685.

Mouse IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A500-005A maps to a region between residues 150 and 200 of human Glyceraldehyde-3-Phosphate Dehydrogenase using the numbering given in entry NP_002037.2 (GeneID 2597).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-463A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Tuberous sclerosis 2 protein (TSC2) forms a heterodimer with TSC1 to integrate cellular growth and stress signals. Defects in the TSC1 and TSC2 gene are responsible for the genetic disorder tuberous sclerosis. The TSC1/TSC2 complex functions in the mTOR pathway by negatively regulating mTOR activity via the small GTP-binding protein Rheb. TSC2 also been shown to interact with FOXO1 transcription factor. TSC2 is also called tuberin, LAM, TSC4, and FLJ43106.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-463A maps to a region between residues 1750 and the C-terminus (residue 1807) of human Tuberous Sclerosis 2 using the numbering given in Swiss-Prot entry P49815 (GeneID 7249).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A300-526A
IP Erklärungen der Abkürzungen ansehen.
Tuberous sclerosis 2 protein (TSC2) forms a heterodimer with TSC1 to integrate cellular growth and stress signals. Defects in the TSC1 and TSC2 gene are responsible for the genetic disorder tuberous sclerosis. The TSC1/TSC2 complex functions in the mTOR pathway by negatively regulating mTOR activity via the small GTP-binding protein Rheb. TSC2 also been shown to interact with FOXO1 transcription factor. TSC2 is also called tuberin, LAM, TSC4, and FLJ43106.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-526A maps to a region between residues 1 and 50 of human Tuberous Sclerosis 2 using the numbering given in Swiss-Prot entry P49815 (GeneID 7249).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-150A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Antibodies were affinity purified using epitopes specific to TSC2 immobilized on solid support.

Rabbit IgG SR: human
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A300-502A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
eIF-4G1 is a component of the EIF4F protein complex that is involved in the processes of mRNA cap recognition, poly (A) binding, and the recruitment of mRNA to the ribosome in the process of protein synthesis. Alternate names for eIF-4G1 include eukaryotic translation initiation factor 4 gamma 1, eIF-4-gamma1, p220, EIF4G1, EIF4G, EIF4F, and DKFZp686A1451.

Rabbit IgG SR: rat, human
Immunogen: synthetic peptide. The epitope recognized by A300-502A maps to a region between residues 575 and 625 of human Eukaryotic Initiation Factor 4 Gamma 1 using the numbering given in entry NP_886553.2 (GeneID 1981).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-774A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Eukaryotic initiation factor 4 gamma 1 (eIF4G1) is one of 2 eIF4G proteins found in human (eIF4G1 and eIF4G3). eIF4G is a subunit of the eIF4F heterotrimeric complex composed of eIF4A, eIF4E, and eIF4G. eIF4F plays a role in recruiting the ribosome to the 5 -end of capped mRNAs during protein synthesis. In the eIF4F complex, eIF4G functions as a scaffold to bridge the cap-binding subunit, eIF4E, with the RNA helicase, eIF4A. Alternate names for eIF4G1 include eIF4GI, eIF-4-gamma 1, p220, EIF4F, EIF4G, and DKFZp686A1451.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-774A maps to a region between residue 200 and 250 of human eukaryotic translation initiation factor 4 gamma, 1 using the numbering given in entry NP_886553.2 (GeneID 1981).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-775A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Eukaryotic initiation factor 4 gamma 1 (eIF4G1) is one of 2 eIF4G proteins found in human (eIF4G1 and eIF4G3). eIF4G is a subunit of the eIF4F heterotrimeric complex composed of eIF4A, eIF4E, and eIF4G. eIF4F plays a role in recruiting the ribosome to the 5 -end of capped mRNAs during protein synthesis. In the eIF4F complex, eIF4G functions as a scaffold to bridge the cap-binding subunit, eIF4E, with the RNA helicase, eIF4A. Alternate names for eIF4G1 include eIF4GI, eIF-4-gamma 1, p220, EIF4F, EIF4G, and DKFZp686A1451.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-775A maps to a region between residue 250 and 300 of human eukaryotic translation initiation factor 4 gamma, 1 using the numbering given in entry NP_886553.2 (GeneID 1981).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-776A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Eukaryotic initiation factor 4 gamma 1 (eIF4G1) is one of 2 eIF4G proteins found in human (eIF4G1 and eIF4G3). eIF4G is a subunit of the eIF4F heterotrimeric complex composed of eIF4A, eIF4E, and eIF4G. eIF4F plays a role in recruiting the ribosome to the 5 -end of capped mRNAs during protein synthesis. In the eIF4F complex, eIF4G functions as a scaffold to bridge the cap-binding subunit, eIF4E, with the RNA helicase, eIF4A. Alternate names for eIF4G1 include eIF4GI, eIF-4-gamma 1, p220, EIF4F, EIF4G, and DKFZp686A1451.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-775A maps to a region between residue 525 and 575 of human eukaryotic translation initiation factor 4 gamma, 1 using the numbering given in entry NP_886553.2 (GeneID 1981).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-634A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A301-774A, A301-775A and A301-776A

Rabbit IgG SR: human
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

729 €

IHC-00566
IHC Erklärungen der Abkürzungen ansehen.
Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.

Rabbit SR: Human, Mouse
Immunogen: synthetic peptide. The epitope recognized by IHC-00566 maps to a region between residue 525 and 575 of human eukaryotic translation initiation factor 4 gamma, 1 using the numbering given in entry NP_886553.2 (GeneID 1981).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A300-462A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
DDB1 (DNA Damage Binding Protein 1) is a subunit of the DNA damage-binding protein complex (DDB) involved in DNA repair. As part of a complex with Cul4-based ubiquitin ligase, Cul4-Ddb1 can directly modify chromatin through the ubiquitination of histones as well as ubiquitinate other chromatin bound factors. A deficiency in Cul4-Ddb1 ubiquitin ligase has been associated with xeroderma pigmentosum, a heritable disease characterized by defects in nucleotide excision repair and skin cancer development. Alternate names for DDB1 include damage-specific DNA-binding protein 1, UV-damaged DNA-binding factor, DDB p127, DDBa, UV-DDB1, xeroderma pigmentosum group E-complementing protein, XPCe, XPE-binding factor, XPE-BF, HBV-X-associated protein 1, XAP-1, and DDBA.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A300-462A maps to a region between residue 1100 and the C-terminus (residue 1140) of human damage-specific DNA binding protein 1 using the numbering given in TrEMBL entry Q13289 (GeneID 1642).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

IHC-00134
IHC Erklärungen der Abkürzungen ansehen.
DDB1 (DNA Damage Binding Protein 1) is a subunit of the DNA damage-binding protein complex (DDB) involved in DNA repair. As part of a complex with Cul4-based ubiquitin ligase, Cul4-Ddb1 can directly modify chromatin through the ubiquitination of histones as well as ubiquitinate other chromatin bound factors. A deficiency in Cul4-Ddb1 ubiquitin ligase has been associated with xeroderma pigmentosum, a heritable disease characterized by defects in nucleotide excision repair and skin cancer development. Alternate names for DDB1 include damage-specific DNA-binding protein 1, UV-damaged DNA-binding factor, DDB p127, DDBa, UV-DDB1, xeroderma pigmentosum group E-complementing protein, XPCe, XPE-binding factor, XPE-BF, HBV-X-associated protein 1, XAP-1, and DDBA.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by IHC-00134 maps to a region between residues 1100 and the C-terminus (residue 1140) of human damage-specific DNA binding protein 1 using the numbering given in TrEMBL entry Q13289 (GeneID 1642).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A301-470A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
NP95/UHRF1 was originally identified as ICBP90 (inverted CCAAT box-binding protein of 90 kDa) in a one-hybrid screen for proteins that bind the topoisomerase IIalpha gene promoter. NP95/UHRF1 is a heterochromatin binding protein that directly interacts with histones and has proposed roles in the DNA damage response, heterochromatin formation, and cell replication. Structurally, NP95/UHRF1 contains an ubiquitin-like domain (NIRF N), a plant homeodomain (PHD), a SRA domain, and a RING domain. The RING domain imparts ubiquitin E3 ligase activity that is histone-specific. This E3 ligase activity is proposed to be important to tumor growth. NP95/UHRF1 expression begins in the G1/S phase and continues through mitosis. It has been shown to be required for entry from G1/G0 as well as the G1/S transition in some cell types. NP95/UHRF1 has been found to be part of the pericentric heterochromatin duplication body (pHDB) and involved in the replication and formation of heterochromatin. Alternate names for NP95 include E3 ubiquitin-protein ligase UHRF1, ubiquitin-like PHD and RING finger domain-containing protein 1, nuclear zinc finger protein 95, HuNp95, RING finger protein 106, UHRF1, RNF106, FLJ21925, and MGC138707.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-470A maps to a region between residue 275 and 325 of human nuclear zinc finger protein Np95 (ubiquitin-like, containing PHD and RING finger domains, 1 ) using the numbering given in entry NP_001041666.1 (G
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

IHC-00554
IHC Erklärungen der Abkürzungen ansehen.
NP95/UHRF1 was originally identified as ICBP90 (inverted CCAAT box-binding protein of 90 kDa) in a one-hybrid screen for proteins that bind the topoisomerase IIalpha gene promoter. NP95/UHRF1 is a heterochromatin binding protein that directly interacts with histones and has proposed roles in the DNA damage response, heterochromatin formation, and cell replication. Structurally, NP95/UHRF1 contains an ubiquitin-like domain (NIRF N), a plant homeodomain (PHD), a SRA domain, and a RING domain. The RING domain imparts ubiquitin E3 ligase activity that is histone-specific. This E3 ligase activity is proposed to be important to tumor growth. NP95/UHRF1 expression begins in the G1/S phase and continues through mitosis. It has been shown to be required for entry from G1/G0 as well as the G1/S transition in some cell types. NP95/UHRF1 has been found to be part of the pericentric heterochromatin duplication body (pHDB) and involved in the replication and formation of heterochromatin.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00554 maps to a region between residue 275 and 325 of human nuclear zinc finger protein Np95 (ubiquitin-like, containing PHD and RING finger domains, 1 ) using the numbering given in entry NP_001041666.1 (G
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A300-744A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
DJ-1 appears to have a function in many biological processes. DJ-1 was first reported as an oncogene and then identified as a gene linked to Parkinson disease, a common neurodegenerative order. DJ-1 has also been observed to play a role in the fertilization process and to act as a sensor for oxidative stress. Alternate names for DJ-1 include protein DJ-1, Oncogene DJ1, Parkinson disease protein 7, PARK7, and FLJ27376.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A300-744A maps to a region between residue 140 and the C-terminus (residue 189) of human DJ-1 (PARK7, Parkinson Disease 7) using the numbering given in entry NP_009193.2 (GeneID 11315 ).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

IHC-00453
IHC Erklärungen der Abkürzungen ansehen.
DJ-1 appears to have a function in many biological processes. DJ-1 was first reported as an oncogene and then identified as a gene linked to Parkinson disease, a common neurodegenerative order. DJ-1 has also been observed to play a role in the fertilization process and to act as a sensor for oxidative stress. Alternate names for DJ-1 include protein DJ-1, Oncogene DJ1, Parkinson disease protein 7, PARK7, and FLJ27376.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by IHC-00453 maps to a region between residue 140 and the C-terminus (residue 189) of human DJ-1 (PARK7, Parkinson Disease 7) using the numbering given in entry NP_009193.2 (GeneID 11315 ).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A302-174A
related products

WB, IP, PLA Erklärungen der Abkürzungen ansehen.
FANCD2 (Fanconi anemia, complementation group D) is a protein involved in DNA repair. Defects in FANCD2 are the cause of Fanconi anemia, a heterogenous autosomal recessive disorder characterized by congenital malformations and a predisposition to cancer. The FANCD2 gene is one of 13 complementation groups that include FANCA, FANCB, FANCC, FANCD1/BRCA2, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ/BRIP1, FANCL, FANCM, and FANCN/PALB2. The FANC members are not homologous proteins but are related by their assembly into a common nuclear complex. Alternative names for FANCD2 include FAD, FAD2, FACD, FANCD, and FA4.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A302-174A maps to a region between residue 1401 and 1451 of human Fanconi anemia, complementation group D2 using the numbering given in entry NP_001018125.1 (GeneID 2177).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

IHC-00624
IHC Erklärungen der Abkürzungen ansehen.
FANCD2 (Fanconi anemia, complementation group D) is a protein involved in DNA repair. Defects in FANCD2 are the cause of Fanconi anemia, a heterogenous autosomal recessive disorder characterized by congenital malformations and a predisposition to cancer. The FANCD2 gene is one of 13 complementation groups that include FANCA, FANCB, FANCC, FANCD1/BRCA2, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ/BRIP1, FANCL, FANCM, and FANCN/PALB2. The FANC members are not homologous proteins but are related by their assembly into a common nuclear complex. Alternative names for FANCD2 include FAD, FAD2, FACD, FANCD, and FA4.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by IHC-00624 maps to a region between residue 1401 and 1451 of human Fanconi anemia, complementation group D2 using the numbering given in entry NP_001018125.1 (GeneID 2177).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

401 €

A303-410A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Dynamin-related protein 1 (Drp1) functions in mitochondrial and peroxisomal division. Drp1 mediates membrane fission through oligomerization into ring-like structures which wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Drp1 is required for normal brain development and facilitates developmentally-regulated apoptosis during neural tube development. Drp1 is also required for a normal rate of cytochrome c release and caspase activation during apoptosis and for mitochondrial fission during mitosis. Drp1 may be involved in vesicle transport. Alternative names for Drp1 include dynamin-1-like protein, Dnm1p/Vps1p-like protein, DVLP, dynamin family member proline-rich carboxyl-terminal domain less, Dymple, dynamin-like protein, dynamin-like protein 4, dynamin-like protein IV, HdynIV, DNM1L, DLP1, and DRP1. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O00429]

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A303-410A maps to a region between residue 686 and 736 of human Dynamin-Related Protein 1 using the numbering given in entry NP_036192.2 (GeneID 10059).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A304-330A
neu

IP Erklärungen der Abkürzungen ansehen.
CD98 is a member of the solute carrier family. It is a cell surface, transmembrane protein. CD98 exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. CD98 plays a role in regulation of intracellular calcium levels and transports L-type amino acids [taken from NCBI Entrez Gene (Gene ID: 6520)].

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A304-330A maps to a region between residue 1 to 50 of human CD98 Heavy Chain using the numbering given in entry NP_002385.3 (GeneID 6520).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A304-331A
related products
neu

WB Erklärungen der Abkürzungen ansehen.
CD98 is a member of the solute carrier family. It is a cell surface, transmembrane protein. CD98 exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. CD98 plays a role in regulation of intracellular calcium levels and transports L-type amino acids [taken from NCBI Entrez Gene (Gene ID: 6520)].

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A304-331A maps to a region between residue 580 to 630 of human CD98 Heavy Chain using the numbering given in entry NP_002385.3 (GeneID 6520).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A311-551A
related products
neu

WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A304-330A and A304-331A

Rabbit IgG SR: human
Immunogen: synthetic peptide. Antibodies were affinity purified using epitopes specific to CD98 immobilized on solid support.
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A302-136A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
CKI delta is a member of the casein kinase 1 (CK1) serine/threonine kinase family of proteins. In mammals, there are seven distinct genes that represent the CK1 family: alpha, beta, gamma-1, gamma-2, gamma-3, delta, and epsilon. CKI delta phosphorylates a number of proteins some of which include the circadian proteins period 1 and period 2. CKI delta is also involved in the Wnt signaling pathway. Alternative names for CKI delta include casein kinase I isoform delta, CKI-delta, CKId, CSNK1D, and HCKID.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A302-136A maps to a region between residue 359 and 409 of human casein kinase 1, delta using the numbering given in entry NP_620693.1 (GeneID 1453). This antibody may have slight crossreactivity with CKI epsil
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A302-048A
related products

WB Erklärungen der Abkürzungen ansehen.
Glycogen synthase kinase 3 beta (GSK3beta) is a proline-directed serine-threonine kinase identified as a kinase responsible for the phosphorylation and inactivation of glycogen synthase. GSK3beta is a critical component of the Wnt/beta-catenin signaling pathway, and its activity results in the inhibition of Wnt signaling by mediating the degradation of beta-catenin. In addition to the Wnt-signaling pathway, GSK3beta is also involved in the Hedgehog, Notch and insulin signaling pathways.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A302-048A maps to a region between residue 370 and 420 of human glycogen synthase kinase-3 beta using the numbering given in entry AAA66475.1 (GeneID 2932).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A302-049A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Glycogen synthase kinase 3 beta (GSK3beta) is a proline-directed serine-threonine kinase identified as a kinase responsible for the phosphorylation and inactivation of glycogen synthase. GSK3beta is a critical component of the Wnt/beta-catenin signaling pathway, and its activity results in the inhibition of Wnt signaling by mediating the degradation of beta-catenin. In addition to the Wnt-signaling pathway, GSK3beta is also involved in the Hedgehog, Notch and insulin signaling pathways.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A302-049A maps to a region between residue 1 and 50 of human glycogen synthase kinase-3 beta using the numbering given in entry AAA66475.1 (GeneID 2932).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-723A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A302-048A and A302-049A

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A301-862A
IP Erklärungen der Abkürzungen ansehen.
Survival motor neuron protein (SMN1) has been identified as the gene that is defective in spinal muscular atrophy (SMA), a neurodegenerative autosomal recessive disease characterized by paralysis and muscular atrophy which results from the loss of motor neurons in the spinal cord. There are two closely related SMN genes that do not appear to be functionally redundant. SMN1 represents the telomeric copy while SMN2 represents the centromeric copy. In the cell, SMN1 is part of a large complex of proteins involved in snRNP biogenesis. The functional role of SMN1 is proposed to play a role in messenger and ribosomal RNA transcription and processing. Alternative names for SMN1 include SMN, SMNT, and SMA.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-862A maps to a region between residue 50 and 100 of human survival of motor neuron 1 using the numbering given in entry NP_000335.1 (GeneID 6606).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A301-863A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
Survival motor neuron protein (SMN1) has been identified as the gene that is defective in spinal muscular atrophy (SMA), a neurodegenerative autosomal recessive disease characterized by paralysis and muscular atrophy which results from the loss of motor neurons in the spinal cord. There are two closely related SMN genes that do not appear to be functionally redundant. SMN1 represents the telomeric copy while SMN2 represents the centromeric copy. In the cell, SMN1 is part of a large complex of proteins involved in snRNP biogenesis. The functional role of SMN1 is proposed to play a role in messenger and ribosomal RNA transcription and processing. Alternative names for SMN1 include SMN, SMNT, and SMA.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A301-863A maps to a region between residue 244 and 294 of human survival of motor neuron 1 using the numbering given in entry NP_000335.1 (GeneID 6606).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A310-663A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
1 each of A301-862A and A301-863A

Rabbit IgG SR: human
Immunogen: synthetic peptide
Bethyl
Icon Datasheet
1 pack

Buy Bulk

486 €

A303-872A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
CD44 is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis [taken from NCBI Entrez Gene (Gene ID: 960)].

Rabbit IgG SR: human
Immunogen: Synthetic peptide. The epitope recognized by A303-872A maps to a region between residue 692 and 742 of human Cell Surface Glycoprotein CD44 using the numbering given in entry NP_000601.3 (GeneID 960).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A302-939A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
PLC-gamma is a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.

Rabbit IgG SR: human
Immunogen: synthetic peptide. The epitope recognized by A302-939A maps to a region between residue 1190 and 1240 of human Phospholipase C, Gamma 1 using the numbering given in entry NP_877963.1 (GeneID 5335).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A302-940A
related products

WB, IP Erklärungen der Abkürzungen ansehen.
PLC-gamma is a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.

Rabbit IgG SR: human, mouse
Immunogen: synthetic peptide. The epitope recognized by A302-940A maps to a region between residue 1240 and 1290 of human Phospholipase C, Gamma 1 using the numbering given in entry NP_877963.1 (GeneID 5335).
Bethyl
Icon Datasheet
100 µl

Buy Bulk

349 €

A311-089A