- Search results for E-375
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115 products were found matching "E-375"!
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Item number: E3375-25.100
Epidermal growth factor (EGF) receptor is a 170kD tyrosine kinase. Ligand binding results in receptor dimerization, autophosphorylation, activation of downstream signaling and lysosomal degradation (1,2). Phosphorylation of Tyr845 in the kinase domain is implicated in stabilizing the activation loop, maintaining the...
Application: | ELISA, IP, WB |
Host: | Rabbit |
Species reactivity: | human, monkey, mouse, rat |
696.00€
*
Item number: E3375-47C.10
Human EGFR (GenBank Accession No. NM_005228), (aa 668-1210) with N, terminal GST tag, expressed in a Baculovirus infected Sf9 cell expression system. , Specific Activity: ~140 U/ug. One unit is defined as the amount of enzyme that will phosphorylate 1pmol of Tyr substarte per minute at pH 7.4 and 30°C. Assay...
Keywords: | EC=2.7.10.1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, Receptor tyrosine-protein kinase erbB-1 |
Application: | Enzyme assays |
985.00€
*
Item number: E3375-01B.100
Epidermal Growth Factor Receptor (EGFR), also named erythroblastic leukemia viral oncogene homolog 1 (ErbB1), is a member of the type I receptor tyrosine kinase superfamily that also includes ErbB2-4. Applications: Suitable for use in Flow Cytometry and Direct ELISA. Other applications not tested. Recommended...
Application: | ELISA, FC |
Host: | Rat |
Species reactivity: | human |
916.00€
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Item number: E3375-01E.50
EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1,-2,-3-4 or HER-1,-2,-3-4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung,...
Keywords: | EC=2.7.10.1, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor tyrosine-protein kinase... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
750.00€
*
Item number: E3375-01J.100
The epidermal growth factor (EGF) receptor is a transmembrane tyrosine kinase that belongs to the HER/ErbB protein family. Ligand binding results in receptor dimerization, autophosphorylation, activation of downstream signaling, internalization, and lysosomal degradation (1,2). Phosphorylation of EGF receptor (EGFR)...
Application: | IP, WB |
Host: | Rabbit |
Species reactivity: | human, monkey, mouse, rat |
682.00€
*
Item number: E3375-01P.100
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression,...
Application: | IHC, IP, WB |
Host: | Mouse |
Species reactivity: | horse, human |
773.00€
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Item number: E3375-02J.100
Applications:, Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 detected phospho-EGFR (Tyr1086) in RIPA lysates , from EGF stimulated A431 cells. , Optimal dilution to be determined by researcher. Storage and Stability: May be stored at 4°C for short-term...
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
863.00€
*
Item number: E3375-03J.1
Applications: , Suitable for use in Immunofluorescence, Immunoprecipitation, Immunogold labeling and electronmicroscopy. Other applications not tested. Recommended Dilution: Immunoprecipitation: Reacts with functional EFR protein-tyrosine kinase complex., Optimal dilutions to be determined by the researcher. Storage...
Application: | IF, IP |
Host: | Mouse |
Species reactivity: | human |
757.00€
*
Item number: E3375-04.500
EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGFa), Heparin-binding EGF (HB-EGF), amphiregulin,, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder,...
Application: | IP |
Host: | Mouse |
Species reactivity: | human, monkey |
840.00€
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Item number: E3375-05A.50
The EGFr which tranduces thebiological effect of EGF is a 170kD glycoprotein containing two functional domains linked by a transmembrane region. The extracellular domain is glyosylated possessing a single binding site. The intracellular domain contains a protein tyrosine kinase. Binding of EGF to receptor...
Application: | ICC, IP, WB |
Host: | Sheep |
Species reactivity: | chicken, human, rat |
416.00€
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Item number: E3375-06B.500
EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1,-2,-3-4 or HER-1,-2,-3-4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung,...
Application: | IHC, IP, WB |
Host: | Mouse |
Species reactivity: | human |
910.00€
*
Item number: E3375-06C.500
EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1,-2,-3-4 or HER-1,-2,-3-4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGFa), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung,...
Application: | IP, WB |
Host: | Mouse |
Species reactivity: | human |
875.00€
*