8 products were found matching "Cay11299-25"!

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Ro 67-4853
Ro 67-4853

Item number: Cay11992-5

Ro 67-4853 is a positive allosteric modulator of metabotropic glutamate 1 receptors (mGluR1), enhancing glutamate-induced calcium signaling through both the human and mouse mGlu1a receptors (pEC50 = 7.16). While only mildly potentiating mGluR5 signaling, this compound is without effect at mGluR2, mGluR4, or mGluR8,...
Keywords: N-(9H-xanthen-9-ylcarbonyl)-carbamic acid, butyl ester
Application: mGluR1 modulator
CAS 302841-89-0
MW: 325.4 D
From 43.00€ *
Review
JMJD2A (human, recombinant, Strep-tagged)
JMJD2A (human, recombinant, Strep-tagged)

Item number: Cay11299-100

Methylation of lysine residues of core histones plays a critical role in the regulation of gene expression. Jumonji domain containing 2A (JMJD2A) is the first reported trimethyllysine-specific histone demethylase. It catalyzes the demethylation of trimethylated forms of histone at lysine residues 9 and 36. Like...
Keywords: KDM4A, JHDM3A, Lysine-specific demethylase 4A, Lysine-specific demethylase 4A, Jumonji domain-containing protein 2A,...
Application: Enzyme activity, WB
Expressed in: E.coli
MW: 42,7 kD
642.00€ *
Review
2-Fluoroethcathinone (hydrochloride)
2-Fluoroethcathinone (hydrochloride)

Item number: Cay11229-5

Fluorine-substituted cathinones, including 4-Fluoromethcathinone (Cay-10859), are psychoactive cathinone derivatives that have been identified in designer drugs marketed as bath salts, plant food, or pills. 2-Fluoroethcathinone (hydrochloride) is a fluorine-substituted synthetic cathinone that has potential for...
Keywords: 2-FEC, 2-(ethylamino)-1-(2-fluorophenyl)-1-propanone, monohydrochloride
Application: Analytical reference standard, Fluorine-substituted synthetic cathinone with potential for abuse
CAS 2446466-63-1
MW: 231.7 D
From 266.00€ *
Review
Galnon (trifluoroacetate salt)
Galnon (trifluoroacetate salt)

Item number: Cay29925-25

Galnon is a galanin (GAL) receptor agonist (KD = 2.9 µM in Bowes cells expressing GAL1 receptors). It inhibits forskolin-induced adenylate cyclase activity in rat hippocampal membranes (EC50 = 10 µM). Galnon (2 mg/kg) reduces the maximal seizure score and increases the latency to first seizure in a mouse model of...
Keywords: Fmoc-beta-Cha-Lys-AMC,...
Application: Galanin receptor agonist
CAS 1217448-19-5
MW: 792.9 D
From 43.00€ *
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2,3-Dimethylmethcathinone (hydrochloride)
2,3-Dimethylmethcathinone (hydrochloride)

Item number: Cay11225-10

2,3-Dimethylmethcathinone (hydrochloride) is a potential designer drug with combined features of amphetamines, cathinones, and phenethylamines. It is structurally related to 4-methylmethcathinone, (Cay-10801), a psychoactive compound that has been identified in products sold as bath salts and plant food. The...
Keywords: 2,3-DMMC, 1-(2,3-dimethylphenyl)-2-(methylamino)propan-1-one, monohydrochloride
Application: Analytical reference standard, Potential designer drug (structurally related to 4-MMC)
CAS 1797981-99-7
MW: 227.7 D
From 266.00€ *
Review
Aflatoxin G1
Aflatoxin G1

Item number: Cay11295-5

Aflatoxin G1 is a mycotoxin that has been found in A. terricola. In vivo, aflatoxin G1 is lethal to ducklings (LD50 = 1.18 mg/kg). It induces hepatocellular carcinoma tumor formation and lethality in rats when administered at doses of 1.4 and 3 mg/animal, respectively. Aflatoxin G1 also inhibits liver and kidney...
Keywords: (7aR,10aS)-3,4,7a,10a-tetrahydro-5-methoxy-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione
Application: Food contaminant, internal standard
CAS 1165-39-5
MW: 328.3 D
From 125.00€ *
Review
AZD 3965
AZD 3965

Item number: Cay19912-25

AZD 3965 is a potent inhibitor of monocarboxylate transporter 1 (MCT1, Ki = 1.6 nM), killing tumor cells that are reliant on glycolysis by blocking lactate transport. It displays six-fold selectivity for MCT1 over MCT2 and is without effect against MCT4 at 10 µM. AZD 3965 increases intratumor lactate levels and...
Keywords: 5-[[(4S)-4-hydroxy-4-methyl-2-isoxazolidinyl]carbonyl]-3-methyl-1-(1-methylethyl)-6-[[5-methyl-3-(trifluoromethyl)-1H-pyra...
Application: SLC16A1 inhibitor
CAS 1448671-31-5
MW: 515.5 D
From 65.00€ *
Review
ARV-771
ARV-771

Item number: Cay21299-5

ARV-771 is a proteolysis-targeting chimera (PROTAC) that drives the degradation of bromodomain and extra terminal domain (BET) family proteins. It is comprised of a BET-binding moiety conjugated via a linker to a von Hippel-Lindau (VHL) E3 ligase-binding moiety. ARV-771 induces degradation of bromodomain-containing...
Keywords: (2S,4R)-1-((S)-2-(tert-butyl)-15-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazep...
Application: PROTAC, BET family protein degradation
CAS 1949837-12-0
MW: 986.6 D
From 77.00€ *
Review