- Search results for Cay11299-25
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8 products were found matching "Cay11299-25"!
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Item number: Cay11992-5
Ro 67-4853 is a positive allosteric modulator of metabotropic glutamate 1 receptors (mGluR1), enhancing glutamate-induced calcium signaling through both the human and mouse mGlu1a receptors (pEC50 = 7.16). While only mildly potentiating mGluR5 signaling, this compound is without effect at mGluR2, mGluR4, or mGluR8,...
Keywords: | N-(9H-xanthen-9-ylcarbonyl)-carbamic acid, butyl ester |
Application: | mGluR1 modulator |
CAS | 302841-89-0 |
MW: | 325.4 D |
From 43.00€
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Item number: Cay11299-100
Methylation of lysine residues of core histones plays a critical role in the regulation of gene expression. Jumonji domain containing 2A (JMJD2A) is the first reported trimethyllysine-specific histone demethylase. It catalyzes the demethylation of trimethylated forms of histone at lysine residues 9 and 36. Like...
Keywords: | KDM4A, JHDM3A, Lysine-specific demethylase 4A, Lysine-specific demethylase 4A, Jumonji domain-containing protein 2A,... |
Application: | Enzyme activity, WB |
Expressed in: | E.coli |
MW: | 42,7 kD |
642.00€
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Item number: Cay11229-5
Fluorine-substituted cathinones, including 4-Fluoromethcathinone (Cay-10859), are psychoactive cathinone derivatives that have been identified in designer drugs marketed as bath salts, plant food, or pills. 2-Fluoroethcathinone (hydrochloride) is a fluorine-substituted synthetic cathinone that has potential for...
Keywords: | 2-FEC, 2-(ethylamino)-1-(2-fluorophenyl)-1-propanone, monohydrochloride |
Application: | Analytical reference standard, Fluorine-substituted synthetic cathinone with potential for abuse |
CAS | 2446466-63-1 |
MW: | 231.7 D |
From 266.00€
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Item number: Cay29925-25
Galnon is a galanin (GAL) receptor agonist (KD = 2.9 µM in Bowes cells expressing GAL1 receptors). It inhibits forskolin-induced adenylate cyclase activity in rat hippocampal membranes (EC50 = 10 µM). Galnon (2 mg/kg) reduces the maximal seizure score and increases the latency to first seizure in a mouse model of...
Keywords: | Fmoc-beta-Cha-Lys-AMC,... |
Application: | Galanin receptor agonist |
CAS | 1217448-19-5 |
MW: | 792.9 D |
From 43.00€
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Item number: Cay11225-10
2,3-Dimethylmethcathinone (hydrochloride) is a potential designer drug with combined features of amphetamines, cathinones, and phenethylamines. It is structurally related to 4-methylmethcathinone, (Cay-10801), a psychoactive compound that has been identified in products sold as bath salts and plant food. The...
Keywords: | 2,3-DMMC, 1-(2,3-dimethylphenyl)-2-(methylamino)propan-1-one, monohydrochloride |
Application: | Analytical reference standard, Potential designer drug (structurally related to 4-MMC) |
CAS | 1797981-99-7 |
MW: | 227.7 D |
From 266.00€
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Item number: Cay11295-5
Aflatoxin G1 is a mycotoxin that has been found in A. terricola. In vivo, aflatoxin G1 is lethal to ducklings (LD50 = 1.18 mg/kg). It induces hepatocellular carcinoma tumor formation and lethality in rats when administered at doses of 1.4 and 3 mg/animal, respectively. Aflatoxin G1 also inhibits liver and kidney...
Keywords: | (7aR,10aS)-3,4,7a,10a-tetrahydro-5-methoxy-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione |
Application: | Food contaminant, internal standard |
CAS | 1165-39-5 |
MW: | 328.3 D |
From 125.00€
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Item number: Cay19912-25
AZD 3965 is a potent inhibitor of monocarboxylate transporter 1 (MCT1, Ki = 1.6 nM), killing tumor cells that are reliant on glycolysis by blocking lactate transport. It displays six-fold selectivity for MCT1 over MCT2 and is without effect against MCT4 at 10 µM. AZD 3965 increases intratumor lactate levels and...
Keywords: | 5-[[(4S)-4-hydroxy-4-methyl-2-isoxazolidinyl]carbonyl]-3-methyl-1-(1-methylethyl)-6-[[5-methyl-3-(trifluoromethyl)-1H-pyra... |
Application: | SLC16A1 inhibitor |
CAS | 1448671-31-5 |
MW: | 515.5 D |
From 65.00€
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Item number: Cay21299-5
ARV-771 is a proteolysis-targeting chimera (PROTAC) that drives the degradation of bromodomain and extra terminal domain (BET) family proteins. It is comprised of a BET-binding moiety conjugated via a linker to a von Hippel-Lindau (VHL) E3 ligase-binding moiety. ARV-771 induces degradation of bromodomain-containing...
Keywords: | (2S,4R)-1-((S)-2-(tert-butyl)-15-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazep... |
Application: | PROTAC, BET family protein degradation |
CAS | 1949837-12-0 |
MW: | 986.6 D |
From 77.00€
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