- Search results for Cay10005191-100
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11 products were found matching "Cay10005191-100"!
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Item number: Cay10009115-100
p300/(CREB binding protein) associated factor (PCAF) belongs to the GCN5/PCAF family of nuclear histone acetyltransferases (HATs). Gcn5/PCAF proteins contain a ~160 residue HAT domain and a conserved bromodomain directly C-terminal to the HAT domain, which has been shown recently to be an acetyl-lysine targeting...
Keywords: | HAT, p300/(CREB binding protein) Associated Factor |
Application: | Enzyme activity |
MW: | 40 kD |
658.00€
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Lipid-based Drug Delivery Tools
Item number: Cay15091-100
1,2-Dioleoyl-sn-glycero-3-PE (1,2-DOPE) is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. The compound features the same diacylglycerol stereochemistry as that of the natural compound. 1,2-DOPE can be used as an emulsifier to facilitate DNA-liposome complex...
Keywords: | 1,2-Dioleoyl-sn-glycero-3-Phosphoethanolamine, 1,2-DOPE, 1,2-dioleoyl-sn-glycero-3-phosphatidylethanolamine |
Application: | Emulsifier |
CAS | 4004-05-1 |
MW: | 744.1 D |
From 109.00€
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Lipid-based Drug Delivery Tools
Item number: Cay15101-100
1-Palmitoyl-2-lauroyl-sn-glycero-3-PC (1,2-PLPC) is a phospholipid containing palmitoyl (16:0) and lauryl (12:0) acyl substituents at the sn-1 and sn-2 positions, respectively. This mixed-chain phosphatidylcholine has been used to study chain-chain contact interactions that contribute to the structural stability of...
Keywords: | 1-Palmitoyl-2-lauroyl-sn-glycero-3-Phosphocholine, PLPC, 1-palmitoyl-2-lauroyl-sn-glycero-3-phosphatidylcholine |
Application: | Phospholipid |
CAS | 82765-47-7 |
MW: | 677.9 D |
From 92.00€
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Item number: Cay10195-100
13-epi-12-oxo Phytodienoic acid (13-epi-12-oxo PDA) is a lipoxygenase metabolite of alpha-linolenic acid in the leaves of green plants such as corn. omega-3 and omega-6 polyunsaturated fatty acids in plants are substrates for plant lipoxygenases. 12-oxo PDA is one of the best studied end metabolites of this...
Keywords: | 13-epi-12-oxo PDA, 4-oxo-5R-(2Z)-2-pentenyl-2-cyclopentene-1S-octanoic acid |
Application: | Bioactive lipid assays |
CAS | 71606-07-0 |
MW: | 292.4 D |
From 82.00€
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Item number: Cay10010591-1
By phosphorylating phosphatidylinositol, phosphoinositide 3-kinases (PI3K), activates diverse cellular functions, including cell growth, differentiation, survival, and motility. Wortmannin is a potent, cell-permeable, and irreversible inhibitor of PI3K enzymes (IC50 = 1-10 nM). However, the class II PI3Ks from...
Keywords: | KY 12420,... |
Application: | PI3K inhibitor |
CAS | 19545-26-7 |
MW: | 428.4 D |
From 60.00€
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Item number: Cay10091-100
Etoricoxib is a dipyridinyl compound that demonstrates high in vitro and ex vivo selectivity for COX-2 over COX-1 in several assays, e.g., in the production of PGE2 by CHO cells expressing either COX-2 (IC50 = 79 nM) or COX-1 (IC50 > 50 µM). Oral etoricoxib is well absorbed and metabolized extensively via oxidation,...
Keywords: | L-791,456, MK-0663, 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine |
Application: | COX-2 inhibitor |
CAS | 202409-33-4 |
MW: | 358.8 D |
From 43.00€
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Item number: Cay10005019-10
Inhibition of histone deacetylase (HDAC) enzymes by compounds such as trichostatin A can have wide ranging effects in cancer, cell differentiation, and other aspects of gene expression regulation. BML-210 is a small molecule inhibitor of HDAC with an IC50 value of 30 µM when tested in HeLa cell nuclear extracts...
Keywords: | CAY10433, N-phenyl-N'-(2-Aminophenyl)hexamethylenediamide, N-(2-aminophenyl)-N'-phenyl-octanediamide |
Application: | HDAC inhibitor |
CAS | 537034-17-6 |
MW: | 339.4 D |
From 43.00€
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Item number: Cay10005913-10
Recently, a series of relatively simple compounds were found to be high-affinity ligands and functional antagonists for the human IP (prostacyclin) receptor. CAY10449 is one of the more potent of these. CAY10449 antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase, blocking...
Keywords: | 4,5-dihydro-N-[4-[[4-(1-methylethoxy)phenyl]carbonyl]phenyl]-1H-imadazol-2-amine |
Application: | cAMP blocker |
MW: | 323.4 D |
From 80.00€
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Item number: Cay10011190-100
The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. There are seven human sirtuins,...
Keywords: | hSIR2, SIR2L1, hSIRT1, 75SirT1, SIR2-like protein 1, SirtT1 75 kDa fragment, Regulatory protein SIR2 homolog 1,... |
Application: | Enzyme activity |
MW: | 89,2 kD |
642.00€
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Item number: Cay10009110-1
W140 is the inactive enantiomer of the sphingosine-1-phosphate receptor 1 (S1P1) antagonist W146 (Cay-10009109). It only weakly binds to S1P1 (Ki = 4.6 µM for the human receptor). W140 has been used as a negative control in vitro and in vivo in the study of S1P1 signaling.Formal Name:...
Keywords: | [3S-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid, mono(trifluoroacetate) |
Application: | S1P1 Antagonist Control |
CAS | 909725-64-0 |
MW: | 456.4 D |
From 105.00€
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Item number: Cay10009150-1
Formulation: This vial contains 5 ml of sodium tartrate solution..
Application: | Kit component |
34.00€
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