21 products were found matching "LKT-C0476.%25"!

It is one of the many alkaloids present in Catharanthus roseus. Can be used as a starting material for the synthesis of the anti-tumor drugs, vinblastine and vincristine. It is less active as an inhibitor of tubulin self-assembly into microtubules than the latter two compounds.

CHK1 inhibitor.

pan-Raf inhibitor.

Caspofungin acetate is a lipopeptide antifungal that inhibits the enzyme 1,3-beta-Glucan synthase, which synthesizes -glucan polymers that form fungal cell walls. Caspofungin acetate is active against a variety of Aspergillus and Candida species and unlike many antifungals, is not metabolized by the cytochrome p450...

Camalexin is a phytoalexin found in various cruciferous plants after exposure to environmental stresses. Studies on acute myeloid leukemia cells show that camalexin selectively decreases cell viability. Several studies have already shown that exposure to camalexin causes cell shrinkage and phospholipid scrambling in...

Macrocyclic lactone.

Cabozantinib or XL-184 is a tyrosine kinase (c-MET, VEGFR2) inhibitor. It has been shown to reduce tumor growth, metastasis, angiogenesis, and induce apoptosis.

CAY10505 is an inhibitor of p110 PI3K. CAY10505 increases endothelial relaxation, normalizes levels of glutathione, nitrate, and nitrite, and alters the vascular endothelial lining in hypertensive rats, improving vascular endothelial dysfunction.

Active derivative of camptothecin. Induces apoptosis and inhibits HIV.

Sitagliptin is a competitive inhibitor of the enzyme dipeptidyl peptidase (DPD-4) and is used as an orally active antihyperglycemic agent.

A carboxylated metabolite of hydroxyzine that has been shown to block the influx of eosinophils into the site of antigen-stimulated skin blisters.