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Anti-​Jumonji Domain Containing 2A (JMJD2A, JHDM3A, KIAA0
USBio
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50 µg

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Anti-Jumonji Domain Containing 2A (JMJD2A, JHDM3A, KIAA0


WB Erklärungen der Abkürzungen ansehen.

Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively. [The UniProt Consortium]

Mouse IgG2a SR: human
Immunogen: Recombinant hum

UniProt ID: O75164

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- Geninformationen GeneID 9682

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Products for: JMJD2, JHDM3 - jumonji domain-containing protein 2 [EC:1.14.11.-]



Schlagworte:
Anti-​KDM4A, EC=1.14.11.-​, Anti-​Lysine-​specific demethylase 4A, Anti-​Jumonji domain-​containing protein 2A, Anti-​JmjC domain-​containing histone demethylation protein 3A, antibody, antibodies, Antikörper

 


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