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17-Octadecynoic Acid
17-Octadecynoic Acid

Item number: Cay90270-1

17-Octadecynoic Acid (17-ODYA) is a fatty acid alkyne. It is a suicide inhibitor of leukotriene B4 20-hydroxylase and renal CYP450 omega-hydroxylase. 17-ODYA (10 µM) completely inhibits the bradykinin-dependent transport of sodium chloride in rat TALH cells. It has been used as a click chemistry probe for labeling...
Keywords: 17-ODYA, Alk-16
Application: Bioactive lipid assays
CAS 34450-18-5
MW: 280.5 D
From 22.00€ *
Review
Olaparib-d4
Olaparib-d4

Item number: Cay9002700-500

Olaparib-d4 is intended for use as an internal standard for the quantification of olaparib (Cay-10621) by GC- or LC-MS. Olaparib is a potent inhibitor of PARP1 and PARP2 (IC50s = 5 and 1 nM, respectively) but is less effective against the PARP tankyrase-1 (IC50 = 1.5 µM). It can be used in cells and in animals,...
Keywords: 4-[[3-[[4-(cyclopropylcarbonyl-d4)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone
Application: GC-MS, LC-MS, Internal standard, PARP1 / PARP2 inhibitor
MW: 438.5 D
From 163.00€ *
Review