2 products were found matching "Cay90230-%25"!

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Item number: Cay90030-25

20-HETE is a cytochrome P450 (CYP450) metabolite postulated to play an autacoid role in the renal and cerebral vasculature. In rat cerebral microvessels, 20-HETE is a vasoconstrictor that mediates pressure-induced autoregulatory vasoconstriction. 20-HETE is excreted mainly as the glucuronide conjugate. The...

Keywords:	20-hydroxy Arachidonic Acid, 20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid
Application:	Bioactive lipid assays
CAS	79551-86-3
MW:	320.5 D

From 217.00€ *

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JNJ-17203212

Item number: Cay30930-25

JNJ-17203212 is a transient receptor potential vanilloid 1 (TRPV1) antagonist (Ki = 72 nM for the recombinant guinea pig channel). It inhibits guinea pig TRPV1 channel activation induced by capsaicin (Cay-92350, Cay-10010743) or pH decrease (IC50s = 58 and 470 nM, respectively). JNJ-17203212 (20 mg/kg) reduces the...

Keywords:	4-[3-(trifluoromethyl)-2-pyridinyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazinecarboxamide
Application:	TRPV1 antagonist
CAS	821768-06-3
MW:	419.3 D

From 158.00€ *

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