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Dihomo-gamma-Linolenic Acid
Dihomo-gamma-Linolenic Acid

Item number: Cay90230-10

Dihomo-gamma-Linolenic Acid (DGLA, 20:3), an elongation product of gamma-linolenic acid (18:3), is rapidly metabolized by fatty acid desaturases to produce arachidonic acid (20:4). DGLA is metabolized through the cyclooxygenase pathway to produce 1-series prostaglandins, including PGE1. In mice, DGLA supplementation...
Keywords: cis-8,11,14-Eicosatrienoic Acid, DGLA, gamma-Homolinolenic Acid, 8Z,11Z,14Z-eicosatrienoic acid
Application: LTB4 receptor antagonist
CAS 1783-84-2
MW: 306.5 D
From 46.00€ *
Review
Melagatran
Melagatran

Item number: Cay9002300-2

Melagatran is an inhibitor of thrombin (Ki = 0.002 µM) and an active metabolite of the prodrug ximelagatran (Cay-16862). It is selective for thrombin over a variety of serine proteases (Kis = 0.6-10.2 µM) but also inhibits trypsin (Ki = 0.004 µM). Melagatran inhibits thrombin-induced aggregation of isolated washed...
Keywords: N-[(1R)-2-[(2S)-2-[[[[4-(aminoiminomethyl)phenyl]methyl]amino]carbonyl]-1-azetidinyl]-1-cyclohexyl-2-oxoethyl]-glycine
Application: Thrombin inhibitor, active ximelagatran metabolite
CAS 159776-70-2
MW: 429.5 D
715.00€ *
Review
Dihomo-gamma-Linolenoyl Ethanolamide
Dihomo-gamma-Linolenoyl Ethanolamide

Item number: Cay90235-10

Dihomo-gamma-linolenoyl ethanolamide is an endocannabinoid containing dihomo-gamma-linoleate in place of the arachidonate moiety of AEA. Dihomo-gamma-linolenoyl ethanolamide binds to recombinant human CB1 and CB2 receptors with Ki values of 857 and 598 nM, respectively. Its specific role and relative importance as a...
Keywords: N-(2-hydroxyethyl)-8Z,11Z,14Z-eicosatrienamide
Application: CB1 receptor ligand, CB2 receptor ligand
CAS 150314-34-4
MW: 349.6 D
From 84.00€ *
Review