Eicosatrienoic acid accumulates in the tissues of animals fed diets deficient in both omega-3 and omega-6 fatty acids. It can be converted to 3-series cysteinyl-leukotrienes but cannot serve as a COX substrate. The kidneys from essential fatty acid deficient rats are less immunogenic when transplanted, and the...

4-methyl-alpha-Pyrrolidinobutiophenone (4-methyl PBP) is a synthetic cathinone with psychoactive properties which has recently been identified in party pills and powders. The metabolism of methyl PBP has been characterized. The biological and toxicological properties of this compound are unknown. This product is...

Mescaline (Cay-11950) is a psychedelic phenethylamine that activates serotonin receptors, with preference for 5-HT2A over 5-HT2C (EC50 = 4 and 24 µM, respectively). Mescaline NBOMe is a derivative of mescaline having an N-(2-methoxybenzyl) addition at the amine. This addition on related phenethylamines increases the...

Eicosatrienoic Acid (20:3omega-3) is a rare polyunsaturated fatty acid of the omega-3 series. In normal humans, it represents less than 0.25% of serum phospholipid fatty acids. However, it is one of the most active essential fatty acids when assayed for the inhibition of fatty acid elongation/desaturation reactions...

5(Z),8(Z),11(Z)-Eicosatrienoic acid ethanolamide is essentially identical to AEA in its agonist binding to CB1 and CB2 receptors. In L cells expressing the human CB1 receptor, the Ki value for 5(Z),8(Z),11(Z)-eicosatrienoic acid ethanolamide and AEA binding is 753 nM. In AtT-20 cells expressing the human CB2...