- Search results for Cay90020-%25
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6 products were found matching "Cay90020-%25"!
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Item number: Cay90020-25
5,6-dehydro Arachidonic acid is an analog of arachidonic acid with an acetylene in the 5,6 position. It inhibits 5-LO in rat basophilic leukemia cells, with a Ki value of 15 µM. In guinea pig leukocytes, 5-LO is inhibited by 5,6-dehydro arachidonic acid with an IC50 value of 10 µM.Formal Name:...
Keywords: | 5,6-dehydro AA, 8Z,11Z,14Z-eicosatrien-5-ynoic acid |
Application: | Bioactive lipid assays |
CAS | 58688-54-3 |
MW: | 302.5 D |
From 131.00€
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Item number: Cay9002014-25
Seratrodast is a potent antagonist of the thromboxane A2 (TXA2) receptor (TP), blocking specific binding of U-46619 (Cay-16450) to guinea pig platelets with an IC50 value of 7.4 nM and platelet aggregation induced by U-44069 (Cay-16440) with an IC50 value of 350 nM. It is metabolized, in liver microsomes, by...
Keywords: | A-73001, AA2414, ABT-001, zeta-(2,4,5-trimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)-benzeneheptanoic acid |
Application: | Thromboxane A2 (TXA2) receptor antagonist |
CAS | 112665-43-7 |
MW: | 354.4 D |
From 60.00€
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Item number: Cay9002067-25
WH-4-023 is a selective inhibitor of the Src family of non-receptor tyrosine kinases (IC50s = 2 and 6 nM for Lck and Src, respectively). It inhibits the related kinases p38alpha and KDR at >300-fold higher concentrations (IC50s = 1.3 and 0.65 µM, respectively). At 1 µM, it has been used in combination with PD...
Keywords: | N-(2,4-dimethoxyphenyl)-N-[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]-carbamic acid, 2,6-dimethylphenyl ester |
Application: | Lck / Src inhibitor |
CAS | 837422-57-8 |
MW: | 568.7 D |
From 53.00€
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Item number: Cay9002073-25
All-trans retinoic acid (ATRA, Cay-11017) is frequently used in cell culture to induce stem cell differentiation or enhance the growth, differentiation, and maintenance of neural cell types. Unfortunately, ATRA is readily susceptible to isomerisation and degradation upon exposure to light or other factors such as...
Keywords: | AGN 190205, BASF 46928, 4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl]-benzoic acid |
Application: | Photostable synthetic all-trans retinoic acid analog |
CAS | 104561-41-3 |
MW: | 332.4 D |
From 43.00€
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Item number: Cay9002880-25
17(R)-Resolvin D3 (17(R)-RvD3) is an aspirin-triggered epimer of resolvin D3 (Cay-13834). It is produced from docosahexaenoic acid (DHA, Cay-90310) by COX-2 in the presence of aspirin via a 17(R)-hydroperoxy DHA (17(R)-HDHA, Cay-10005099) intermediate and has been found in mouse inflammatory exudates. 17(R)-RvD3...
Keywords: | 17(R)-RvD3, 17-epi-Resolvin D3, Aspirin-triggered Resolvin D3, AT-RvD3,... |
Application: | Aspirin-triggered resolvin D3 epimer |
CAS | 1427475-53-3 |
MW: | 376.5 D |
From 205.00€
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Item number: Cay9002910-25
(+)-JQ1 (free acid) is an inhibitor of bromodomain and extra terminal domain (BET) family proteins (Kds = 128, 59.5, 49.0, and 190 nM for JQ1 binding to bromodomains of BRD2, BRD3, BRD4, and BRDT, respectively), blocking their interaction with acetylated histones. Enantiomerically pure (+)-JQ1 (Cay-11187) binds to...
Keywords: | (6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid |
Application: | BET family protein inhibitor |
CAS | 202592-23-2 |
MW: | 400.9 D |
From 73.00€
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