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20-HETE
20-HETE

Item number: Cay90030-25

20-HETE is a cytochrome P450 (CYP450) metabolite postulated to play an autacoid role in the renal and cerebral vasculature. In rat cerebral microvessels, 20-HETE is a vasoconstrictor that mediates pressure-induced autoregulatory vasoconstriction. 20-HETE is excreted mainly as the glucuronide conjugate. The...
Keywords: 20-hydroxy Arachidonic Acid, 20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid
Application: Bioactive lipid assays
CAS 79551-86-3
MW: 320.5 D
From 217.00€ *
Review
N-Desethylamiodarone (hydrochloride)
N-Desethylamiodarone (hydrochloride)

Item number: Cay9000537-250

Amiodarone (Cay-15213) is a class III antiarrhythmic agent, in that it prolongs both cardiac action potential and refractoriness by blocking potassium currents. It inhibits the voltage-gated potassium channel hERG, also known as KCNH2, with an IC50 value of 1 µM. In humans, cytochrome P450 3A is involved in the...
Keywords: (2-butyl-3-benzofuranyl)[4-[2-(ethylamino)ethoxy]-3,5-diiodophenyl]-methanone, monohydrochloride
Application: Antiarrhythmic agent
CAS 96027-74-6
MW: 653.7 D
From 109.00€ *
Review