4 products were found matching "Cay9000497-%25"!
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SR 144528
Item number: Cay9000491-25
SR 144528 is a cannabinoid 2 (CB2) receptor antagonist (Ki = 0.6 nM). It is selective for CB2 over CB1 receptors in CHO cells expressing the human receptors (Ki = 437 nM). SR 144528 reverses CP 55,940-induced inhibition of forskolin-induced adenylyl cyclase activity in CHO cells expressing human CB2 receptors (EC50...
| Keywords: | SR144528,... |
| Application: | CB2 antagonist |
| CAS | 192703-06-3 |
| MW: | 476.1 D |
From 158.00€
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PRIMA-1MET
Item number: Cay9000487-25
Mutations in the p53 tumor suppressor are found in many different neoplastic cells. PRIMA-1 (Cay-63520) is a unique anti-oncogenic substance that re-activates the apoptotic function of mutant p53 via conformational modulation of function-specific epitopes. PRIMA-1MET is a methylated derivative of PRIMA-1 that...
| Keywords: | APR 246, 2-(hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one |
| Application: | Mutant p53 apoptotic function re-activator |
| CAS | 5291-32-7 |
| MW: | 199.3 D |
From 92.00€
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Ionomycin
Item number: Cay10004974-5
Ionomycin is a calcium ionophore originally isolated from S. conglobatus. It induces intracellular calcium mobilization in X. laevis oocytes when used at a concentration of 5 µM. Ionomycin (5 µM) induces the formation of neutrophil extracellular traps (NETs) in isolated human neutrophils. Ionomycin in combination...
| Keywords: | (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro... |
| Application: | Ca Ionophore |
| CAS | 56092-81-0 |
| MW: | 709 D |
From 60.00€
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Resolvin D2 methyl ester
Item number: Cay9001497-25
Resolvin D2 (RvD2) (Cay-10007279) is a lipid mediator biosynthesized by the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase. It evokes diverse anti-inflammatory effects which may mediate the resolution of inflammation. RvD2 methyl ester is a methyl ester version of the free acid which may...
| Keywords: | 7(S),16(R),17(S)-Resolvin D2 methyl ester, RvD2 methyl ester, 7S,16R,17S-trihydroxy-4Z,8E,10Z,12E,14E,19Z-docosahexaenoic... |
| Application: | Bioactive lipid assays |
| CAS | 810668-53-2 |
| MW: | 390.5 D |
From 205.00€
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