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SR 144528
SR 144528

Item number: Cay9000491-25

SR 144528 is a cannabinoid 2 (CB2) receptor antagonist (Ki = 0.6 nM). It is selective for CB2 over CB1 receptors in CHO cells expressing the human receptors (Ki = 437 nM). SR 144528 reverses CP 55,940-induced inhibition of forskolin-induced adenylyl cyclase activity in CHO cells expressing human CB2 receptors (EC50...
Keywords: SR144528,...
Application: CB2 antagonist
CAS 192703-06-3
MW: 476.1 D
From 158.00€ *
Review
20-HETE
20-HETE

Item number: Cay90030-25

20-HETE is a cytochrome P450 (CYP450) metabolite postulated to play an autacoid role in the renal and cerebral vasculature. In rat cerebral microvessels, 20-HETE is a vasoconstrictor that mediates pressure-induced autoregulatory vasoconstriction. 20-HETE is excreted mainly as the glucuronide conjugate. The...
Keywords: 20-hydroxy Arachidonic Acid, 20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid
Application: Bioactive lipid assays
CAS 79551-86-3
MW: 320.5 D
From 217.00€ *
Review