9 products were found matching "Cay9000325-%25"!

AV-Ceramide is a fluorescently tagged probe consisting of C-10 ceramide with an anthrylvinyl (AV) group attached to the end of the acyl chain. The AV group, being relatively small and non-polar, readily orients within the central region of a lipid bilayer. The transfer or transport of lipids labeled with AV is...

17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DHA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARgamma agonist (EC50 = ~200 nM), and to...

NADPH is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate (NADP+) and acts as an electron donor in various biological reactions. In plants, NADPH is produced by ferredoxin-NADP+ reductase in the last step of the electron chain during photosynthesis. In animals is it predominantly...

Tafluprost ethyl amide is a derivative of the tafluoprost (free acid) prodrug tafluprost (Cay-10005440). Formulations containing tafluprost ethyl amide have been used in the treatment of eyelash hypotrichosis and in cosmetics.Formal Name:...

2,3-dinor-11beta-PGF2alpha-d9 is intended for use as an internal standard for the quantification of 2,3-dinor-11beta-PGF2alpha (Cay-16530) by GC- or LC-MS. 2,3-dinor-11beta-PGF2alpha is a metabolite of PGD2 (Cay-12010). Urinary excretion of 2,3-dinor-11beta-PGF2alpha is increased in patients with mast cell...

JWH 018 is a synthetic cannabinoid (CB) that potently activates the central CB1 and peripheral CB2 receptors (Ki = 9.0 and 2.94 nM, respectively). This cannabimimetic compound has frequently been found in herbal blends. JWH 424 is an 8-bromonaphthyl derivative of JWH 018 which shows a reduced selectivity for CB1...

Carnitine facilitates the transport of fatty acids into the mitochondria to be used in fatty acid metabolism. It does so by accepting acyl groups from fatty acids complexed with coenzyme A, which yields esterified carnitine or acylcarnitines that enable the transport of fatty acyl groups into the inner mitochondrial...

All-trans retinoic acid (ATRA, Cay-11017) is frequently used in cell culture to induce stem cell differentiation or enhance the growth, differentiation, and maintenance of neural cell types. Unfortunately, ATRA is readily susceptible to isomerisation and degradation upon exposure to light or other factors such as...

Lathosterol is an intermediate in the biosynthesis of cholesterol. Serum levels of lathosterol correlate with cholesterol synthesis and have been used as biomarkers of excess cholesterol production. Lathosterol accumulates in lathosterolosis, a disorder characterized by a deficiency of lathosterol 5-desaturase, the...