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Nonactin, Monactin, and Dinactin Mixture
Item number: Cay19468-10
Nonactin, monactin, and dinactin mixture is a macrotetralide antibiotic. This product is a mixture of the macrotetralide antibiotic homologs nonactin, monactin (Cay-25742), and dinactin (Cay-20752) that all act as ionophores for monovalent cations. Nonactin is a mitochondrial membrane uncoupler and an inhibitor of...
| Keywords: | (1R,2R,5R,7R,10S,11S,14S,16S,19R,20R,23R,25R,28S,29S,32S,34S)-2,5,11,14,20,23,29,32-octamethyl-4,13,22,31,37,38,39,40-octa... |
| Application: | Macrotetrolide antibiotic, monovalent cation ionophore |
| MW: | 736.9 D |
From 66.00€
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AZ 12216052
Item number: Cay29460-25
AZ 12216052 is a positive allosteric modulator of metabotropic glutamate receptor 8 (mGluR8). It potentiates glutamate-induced [35S]GTPgammaS binding in GHEK cells expressing human mGluR8b (EC50 = 1 µM). In a cell-based model of Parkinson's disease, AZ 12216052 inhibits MPP+-induced decreases in the viability of...
| Keywords: | 2-[[(4-bromophenyl)methyl]thio]-N-[4-(1-methylpropyl)phenyl]-acetamide |
| Application: | mGluR8 positive allosteric modulator |
| CAS | 1290628-31-7 |
| MW: | 392.4 D |
From 52.00€
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