- Search results for Cay89420-%25
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10 products were found matching "Cay89420-%25"!
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Item number: Cay89740-25
CAY10398 is an inhibitor of histone deacetylase (HDAC1) with an IC50 value of 10 µM. Similar potency is observed with trapoxin A and B, whereas trichostatin A is more potent inhibitor of the enzyme. Trichostatin A also selectively inhibits the removal of acetyl groups from the amino-terminal lysine residues of core...
Keywords: | MD 85, PX 089274, 4-(dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]-benzamide |
Application: | HDAC1 inhibitor |
CAS | 193551-00-7 |
MW: | 293.4 D |
From 28.00€
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Item number: Cay28940-25
The Comprehensive Kinase Screening Library consists of 11 plates and contains more than 850 selective and non-selective kinase inhibitors in a 96-well Matrix(TM) tube rack format as 10 mM stock solutions in DMSO. This comprehensive library includes inhibitors of a wide range of lipid, receptor and non-receptor...
Application: | HTS, kinase inhibitor screening |
5,182.00€
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Item number: Cay29480-25
SKF 83566 is a dopamine D1 receptor antagonist. In vivo, SKF 83566 (0.005, 0.01, and 0.03 mg/kg) reduces dexbenzetimide- and scopolamine-induced locomotor stereotypy in rats. It decreases ghrelin-induced increases in novel object exploration and food intake in rats when administered at a dose of 100 µg/kg. SKF 83566...
Keywords: | 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol, monohydrobromide |
Application: | Dopamine D1 receptor antagonist |
CAS | 108179-91-5 |
MW: | 413.2 D |
From 84.00€
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Item number: Cay89320-25
8-Hydroxy-2'-deoxyguanosine is produced by oxidative damage of DNA by reactive oxygen and nitrogen species, including hydroxyl radical and peroxynitrite. It serves as a measure of oxidative stress in biological systems.Formal Name: 2'-deoxy-7,8-dihydro-8-oxo-guanosine. CAS Number: 88847-89-6. Synonyms:...
Keywords: | 8-OH-dG, 2'-deoxy-8-hydroxy-guanosine |
Application: | Oxidative stress studies |
CAS | 88847-89-6 |
MW: | 283.2 D |
From 60.00€
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Item number: Cay89820-25
Carnosic acid is an active diterpene found in rosemary (R. officinalis) and common sage (S. officinalis). Its antioxidant properties include inhibition of lipid peroxidation and scavenging of peroxyl radicals. Carnosic acid has been shown to be cytotoxic towards various human cancer cell lines, reducing cell...
Keywords: | Rosamox(TM), RoseOx(R), Salvin,... |
Application: | Antioxidant |
CAS | 3650-09-7 |
MW: | 332.4 D |
From 50.00€
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Item number: Cay19420-25
CC-115 is a dual inhibitor of mammalian target of rapamycin (mTOR) and DNA protein kinase (DNA-PK, IC50s = 0.021 and 0.013 µM, respectively). It is selective for mTOR and DNA-PK over PI3Kalpha, ATM, and ATR (IC50s = 0.85, >30, and >30 µM, respectively). CC-115 inhibits growth in a panel of 123 cancer cell lines,...
Keywords: | 1-ethyl-3,4-dihydro-7-[2-methyl-6-(1H-1,2,4-triazol-5-yl)-3-pyridinyl]-pyrazino[2,3-b]pyrazin-2(1H)-one |
Application: | DNA-PK / mTOR inhibitor |
CAS | 1228013-15-7 |
MW: | 336.4 D |
From 43.00€
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Item number: Cay29804-25
TC-FPR 43 is an agonist of formyl peptide receptor 1 (FPR1) and FPR2, which was previously known as formyl peptide receptor-like 1 (FPRL1). TC-FPR 43 induces calcium flux in CHO cells expressing human FPR2, Galpha15, and aequorin (EC50 = 0.044 µM) and in CHO-K1 cells expressing either human FPR1, human FPR2, mouse...
Keywords: | FPR Agonist 43, N-(4-chlorophenyl)-N'-[2,3-dihydro-1-methyl-5-(1-methylethyl)-3-oxo-2-phenyl-1H-pyrazol-4-yl]-urea |
Application: | FPR1 / FPR2 agonist |
CAS | 903895-98-7 |
MW: | 384.9 D |
From 147.00€
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Item number: Cay20894-25
Diallyl sulfide is a thioether found in garlic that can modulate the cytochrome P450 drug metabolizing system, activate the constitutive androstane receptor to regulate multidrug resistance-associated proteins, and upregulate the expression of detoxifying enzymes. Garlic-derived organosulfides such as diallyl...
Keywords: | Allyl Sulfide, DAS, NSC 20947, 3,3'-thiobis-1-propene |
Application: | NR1I3 activator, Detoxifying enzyme expression upregulator |
CAS | 592-88-1 |
MW: | 114.2 D |
44.00€
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Item number: Cay19480-25
CWHM12 is an analog of RGD peptide (Cay-14501), a tripeptide that inhibits integrin-ligand interactions in studies related to cell adhesion, migration, growth, and differentiation. CWHM12 selectively inhibits alphav integrins (IC50s = 1.8, 0.8, 61, 1.5, and 0.2 nM for alphavbeta1, alphavbeta3, alphavbeta5,...
Keywords: | (3S)-N-[3-hydroxy-5-[(1,4,5,6-tetrahydro-5-hydroxy-2-pyrimidinyl)amino]benzoyl]glycyl-3-[3-bromo-5-(1,1-dimethylethyl)phen... |
Application: | Integrin alpha-V inhibitor |
CAS | 1564286-55-0 |
MW: | 590.5 D |
From 50.00€
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Item number: Cay34890-25
SN-011 is a stimulator of interferon genes (STING) antagonist. It binds to the STING cyclic dinucleotide binding site (Kd = 4.03 nM) and inhibits 2'3'-cGAMP-induced Ifnb expression in mouse embryonic fibroblasts (MEFs), mouse bone marrow-derived macrophages (BMDMs), and human foreskin fibroblasts (HFFs, IC50s =...
Keywords: | GUN35901, N-[3-[[(4-fluorophenyl)sulfonyl]amino]-4-hydroxyphenyl]-[1,1'-biphenyl]-4-carboxamide |
Application: | STING antagonist |
CAS | 2249435-90-1 |
MW: | 462.5 D |
From 66.00€
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