- Search results for Cay82235-%25
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9 products were found matching "Cay82235-%25"!
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Item number: Cay82130-25
MAHMA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 1 minute and 3 minutes at 37°C and 22-25°C, respectively, (pH 7.4) to liberate 2 moles of NO per mole of parent compound.Formal Name:...
Keywords: | Methylamine hexamethylene methylamine NONOate, (Z)-1-[N-Methyl-N-[6-(N-methylammoniohexyl)amino]]diazen-1-ium-1,2-diolate |
Application: | NO donor |
CAS | 146724-86-9 |
MW: | 204.3 D |
From 48.00€
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Item number: Cay18223-25
Primaquine is an established antimalarial drug used in the treatment of persistent liver forms of P. vivax or P. ovale infection for its ability to kill late-stage gametocytes and hypnozoites. In historical terms, this aminoquinoline was the stimulus for the discovery of glucose-6-phosphate (G6P) dehydrogenase...
Keywords: | NSC 149765, N4-(6-methoxy-8-quinolinyl)-1,4-pentanediamine, diphosphate |
Application: | Antimalarial |
CAS | 63-45-6 |
MW: | 455.3 D |
From 48.00€
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Item number: Cay28832-25
HDAC8-IN-1 is an inhibitor of histone deacetylase 8 (HDAC8, IC50 = 27.2 nM). It is selective for HDAC8 over HDAC1-3, -4, -6, -10, and -11 (IC50s = >3,000 nM for all). HDAC8-IN-1 is cytotoxic to A549, H1299, and CL1-5 lung cancer cells (IC50s = 7.9, 7.2, and 7 µM, respectively).Formal Name:...
Keywords: | MDK-7933, (2E)-N-hydroxy-3-(5-methoxy[1,1':4',1''-terphenyl]-2-yl)-2-propenamide |
Application: | HDAC8 inhibitor |
CAS | 1417997-93-3 |
MW: | 345.4 D |
From 60.00€
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Item number: Cay29238-25
BX-517 is an inhibitor of the serine/threonine kinase 3-phosphoinositide-dependent protein kinase 1 (PDK1, IC50 = 6 nM). It binds to the ATP binding pocket of PDK1, inhibits Akt2 activation induced by PDK1 in a cell-free assay (IC50 = 20 nM), and inhibits Akt phosphorylation in PC3 cells.Formal Name:...
Keywords: | PDK1 Inhibitor II, N-[2,3-dihydro-2-oxo-3-[1-(1H-pyrrol-2-yl)ethylidene]-1H-indol-5-yl]-urea |
Application: | PDK1 inhibitor |
CAS | 850717-64-5 |
MW: | 282.3 D |
From 147.00€
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Item number: Cay14832-25
Ibudilast is an inhibitor of phosphodiesterase 4 (PDE4, IC50s = 54, 65, 239, and 166 nM for PDE4A-D, respectively). It is selective for PDE4 over PDE1, PDE7A, PDE7B, and PDE9A (IC50s = >10,000 nM for all) but does inhibit PDE3A, PDE3B, and PDE5A (IC50s = 1,600, 2,700, and 3,510 nM, respectively). Ibudilast inhibits...
Keywords: | AV 411, KC-404, 2-methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-1-propanone |
Application: | PDE4 inhibitor |
CAS | 50847-11-5 |
MW: | 230.3 D |
From 60.00€
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Item number: Cay11832-25
Corilagin is a polyphenol and hydrolyzable tannin that can be isolated from a variety of plants. It inhibits squalene epoxidase (IC50 = 4.0 µM), a key enzyme in cholesterol synthesis. Corilagin also has various anti-inflammatory and anti-cancer effects.Formal Name: cyclic...
Keywords: | cyclic 3,6-[(1R)-4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate]... |
Application: | Squalene epoxidase inhibitor |
CAS | 23094-69-1 |
MW: | 634.5 D |
From 43.00€
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Item number: Cay35822-25
Bayogenin is a triterpene that has been found in B. perennis and has enzyme inhibitory activity. It inhibits rabbit muscle glycogen phosphorylase (IC50 = 68 µM).Formal Name: (2beta,3beta,4alpha)-2,3,23-trihydroxy-olean-12-en-28-oic acid. CAS Number: 6989-24-8. Molecular Formula: C30H48O5. Formula Weight: 488.7....
Keywords: | (2beta,3beta,4alpha)-2,3,23-trihydroxy-olean-12-en-28-oic acid |
Application: | Triterpene, Enzyme inhibitory agent |
CAS | 6989-24-8 |
MW: | 488.7 D |
From 69.00€
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Item number: Cay82235-5
AAPH is a water-soluble azo compound which is used extensively as a free radical generator, often in the study of lipid peroxidation and the characterization of antioxidants. Decomposition of AAPH produces molecular nitrogen and 2 carbon radicals. The carbon radicals may combine to produce stable products or react...
Keywords: | 2,2'-azobis-2-methyl-propanimidamide, dihydrochloride |
Application: | Free radical generator, lipid peroxidation studies |
CAS | 2997-92-4 |
MW: | 271.2 D |
From 85.00€
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Item number: Cay80230-25
NG,NG-dimethyl-L-arginine (ADMA) is an endogenous inhibitor of nitric oxide synthase (NOS). It is formed from arginine by protein arginine methyltransferases (PRMTs) and degraded by dimethylarginine dimethylaminohydrolases (DDAHs) and alanine-glyoxylate aminotransferase 2 (AGXT2). ADMA levels are increased...
Keywords: | ADMA, Asymmetric dimethylarginine, N5-[(dimethylamino)iminomethyl]-L-ornithine, dihydrochloride |
Application: | NOS inhibitor |
CAS | 220805-22-1 |
MW: | 275.2 D |
From 34.00€
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