16 products were found matching "Cay81025.1-%25"!

DPTA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of three hours and five hours at 37°C and 22-25°C, pH 7.4, respectively, to liberate 2 moles of NO per mole of parent compound.Formal Name:...

AAT-008 is an orally bioavailable and potent antagonist of the prostaglandin E2 (PGE2) receptor subtype 4 (EP4, IC50 = 16.3 nM in a human EP4 functional assay). It is selective for EP4 with IC50 values of 2.4, 1,890, >20,000, and >20,000 nM for binding to human recombinant EP4, EP2, EP1, and EP3, respectively....

1,3-PBIT is a potent inhibitor of iNOS with a Ki of 47 nM compared to Ki values for eNOS and nNOS are 9 and 0.25 µM, respectively, for the purified human enzymes. Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability.Formal Name:...

M50054 is a cell-permeable inhibitor of the activation of caspase-3, blocking characteristic features of apoptosis, including DNA fragmentation and externalization of phosphatidylserine. It blocks apoptosis in a variety of cell lines induced by different stimuli, including Fas ligand and etoposide (Cay-12092)....

4-Methylumbelliferyl-alpha-D-glucopyranoside is a fluorogenic substrate for alpha-glucosidase. 4-Methylumbelliferyl-alpha-D-glucopyranoside is cleaved by alpha-glucosidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low...

17-phenyl trinor Prostaglandin F2alpha (17-phenyl trinor PGF2alpha) is a metabolically stable analog of PGF2alpha and is a potent agonist for the FP receptor. It binds to the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2alpha. At the rat recombinant FP receptor expressed...

NS 2028 is a specific inhibitor of soluble guanylyl cyclase. It inhibits purified bovine lung guanylyl cyclase in a concentration dependent and irreversible manner with IC50 values of 30 and 200 nM for basal and NO-stimulated enzymes, respectively. S-nitroso-glutathione-enhanced guanylyl cyclase activity in mouse...

Trimetazidine-d8 is intended for use as an internal standard for the quantification of trimetazidine by GC- or LC-MS. Trimetazidine is a cardioprotective agent. It decreases ischemia-reperfusion injury-induced pyroptosis in H9c2 rat cardiomyocytes when used at concentrations ranging from 5 to 100 µM. In vivo,...

17-phenyl trinor Prostaglandin F2alpha-d4 (17-phenyl trinor PGF2alpha-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 17-phenyl trinor PGF2alpha by GC- or LC-mass spectrometry. 17-phenyl trinor PGF2alpha is a metabolically...

Grosvenorine is a flavonol glycoside that has been found in S. grosvenorii and has antibacterial and antioxidant activities. It is active against methicillin-sensitive and -resistant S. aureus, as well as Enterococcus, in disc diffusion assays when used at a concentration of 250 µg/ml. Grosvenorine scavenges ABTS...

Oxandrolone (Cay-9001819) is an analytical reference standard categorized as an anabolic androgenic steroid. It has been detected as an adverse analytical finding (AAF) during anti-doping testing. Oxandrolone is regulated as a Schedule III compound in the United States. This product is intended for research and...

(-)-Perillyl alcohol is a monoterpene alcohol that has been found in lavender essential oil and has diverse biological activities. It reduces production of hydroperoxidienes and thiobarbituric acid reactive substances (TBARS) in vitro in a concentration-dependent manner. (-)-Perillyl alcohol inhibits PANC-1...