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FH535
FH535

Item number: Cay18001-25

FH535 is an inhibitor of beta-catenin/Tcf-mediated transcription and an antagonist of ligand-dependent activation of PPARgamma and PPARdelta. At 15 µM, FH535 blocks the recruitment of beta-catenin and GRIP1 to PPARgamma and PPARdelta. Presumably through these actions, FH535 is selectively toxic to some carcinoma...
Keywords: 2,5-dichloro-N-(2-methyl-4-nitrophenyl)-benzenesulfonamide
Application: Wnt/beta-catenin signaling Inhibitor, PPARgamma/delta antagonist
CAS 108409-83-2
MW: 361.2 D
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