3 products were found matching "Cay71810"!
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T0901317
Item number: Cay71810-10
The Liver X Receptors (LXRalpha and LXRbeta) are nuclear hormone receptors whose native ligands are oxysterols, such as 22(R)-hydroxycholesterol. The LXRs regulate the oxysterol-induced expression of cholesterol 7alpha-hydroxylase, the rate limiting enzyme of classic bile acid synthesis. T0901317 is a potent and...
| Keywords: | N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide |
| Application: | LXRalpha agonist, LXRbeta agonist |
| CAS | 293754-55-9 |
| MW: | 481.3 D |
From 54.00€
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Calcitriol
Item number: Cay71820-10
Calcitriol is a vitamin D3 receptor agonist and active metabolite of vitamin D3 (Cay-11792). It is formed via a multi-step process, in which vitamin D3 undergoes hydroxylation to 25-hydroxy vitamin D3 (Cay-9000683) in the liver, followed by further hydroxylation at the 1alpha-position in the kidney. Calcitriol binds...
| Keywords: | 1alpha,25-dihydroxy Vitamin D3, 9,10-secocholesta-5Z,7E,10(19)-triene-1alpha,3beta,25-triol |
| Application: | Metabolic studies |
| CAS | 32222-06-3 |
| MW: | 416.6 D |
From 114.00€
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(Z)-Guggulsterone
Item number: Cay71800-10
(Z)-Guggulsterone demonstrates antitumor-promoting effects inhibiting both constitutive and interleukin-6-induced STAT3 activation in human multiple myeloma cells and suppressing the VEGF-VEGF/R2-Akt signaling axis in DU145 human prostate cancer cells.Formal Name: pregna-4,17Z(20)-diene-3,16-dione. CAS Number:...
| Keywords: | pregna-4,17Z(20)-diene-3,16-dione |
| Application: | FXR antagonist |
| CAS | 39025-23-5 |
| MW: | 312.5 D |
From 60.00€
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