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(Z)-Guggulsterone
(Z)-Guggulsterone

Item number: Cay71800-5

(Z)-Guggulsterone demonstrates antitumor-promoting effects inhibiting both constitutive and interleukin-6-induced STAT3 activation in human multiple myeloma cells and suppressing the VEGF-VEGF/R2-Akt signaling axis in DU145 human prostate cancer cells.Formal Name: pregna-4,17Z(20)-diene-3,16-dione. CAS Number:...
Keywords: pregna-4,17Z(20)-diene-3,16-dione
Application: FXR antagonist
CAS 39025-23-5
MW: 312.5 D
From 60.00€ *
Review
T0901317
T0901317

Item number: Cay71810-100

The Liver X Receptors (LXRalpha and LXRbeta) are nuclear hormone receptors whose native ligands are oxysterols, such as 22(R)-hydroxycholesterol. The LXRs regulate the oxysterol-induced expression of cholesterol 7alpha-hydroxylase, the rate limiting enzyme of classic bile acid synthesis. T0901317 is a potent and...
Keywords: N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide
Application: LXRalpha agonist, LXRbeta agonist
CAS 293754-55-9
MW: 481.3 D
From 54.00€ *
Review