- Search results for Cay71750
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6 products were found matching "Cay71750"!
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Item number: Cay71750-5
Troglitazone is a selective agonist of peroxisome proliferator-activated receptor gamma (PPARgamma, EC50s = 0.78 and 0.55 µM for the mouse and human receptors, respectively, in a transactivation assay). It is selective for PPARgamma over PPARalpha and PPARdelta, at which it is inactive at concentrations up to 10 µM....
Keywords: | 5-[[4-[(3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-2,4-thiazolidinedione |
Application: | PPARgamma agonist |
CAS | 97322-87-7 |
MW: | 441.5 D |
From 81.00€
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Item number: Cay71740-50
Rosiglitazone is an agonist of peroxisome proliferator-activated receptor gamma (PPARgamma). It activates PPARgamma1 and PPARgamma2 in reporter assays (EC50s = 30 and 100 nM, respectively). Rosiglitazone selectively activates chimeras containing the ligand-binding domains (LBDs) of PPARgamma over PPARalpha and...
Keywords: | BRL 49653, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione |
Application: | PPARgamma agonist |
CAS | 122320-73-4 |
MW: | 357.4 D |
From 43.00€
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Item number: Cay71742-50
Rosiglitazone is an agonist of peroxisome proliferator-activated receptor gamma (PPARgamma). It activates PPARgamma1 and PPARgamma2 in reporter assays (EC50s = 30 and 100 nM, respectively). Rosiglitazone selectively activates chimeras containing the ligand-binding domains (LBDs) of PPARgamma over PPARalpha and...
Keywords: | 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione, monopotassium salt |
Application: | PPARgamma agonist |
CAS | 316371-84-3 |
MW: | 395.5 D |
From 43.00€
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Item number: Cay71745-50
Pioglitazone is an agonist of the peroxisome proliferator-activated receptor gamma (PPARgamma, EC50 = ~500-600 nM for both human and murine PPARgamma). It is selective for PPARgamma over PPARalpha, exhibiting low level activation of PPARalpha at 1 µM and 5.4-fold activation at a concentration of 10 µM. Pioglitazone...
Keywords: | U-72107, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione |
CAS | 111025-46-8 |
MW: | 356.4 D |
From 30.00€
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Item number: Cay71730-50
Ciglitazone is an antidiabetic drug of the thiazolidinedione structural class. Ciglitazone is a potent and selective PPARgamma ligand. It binds to the PPARgamma ligand-binding domain with an EC50 of 3.0 µM. Ciglitazone is active in vivo as an anti-hyperglycemic agent in the ob/ob mouse model.Formal Name:...
Keywords: | ADD 3878, U-63287, 5-[[4-[(1-methylcyclohexyl)methoxy]phenyl]methyl]-2,4-thiazolidinedione |
Application: | PPARgamma ligand |
CAS | 74772-77-3 |
MW: | 333.4 D |
From 31.00€
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Item number: Cay71770-50
AM80 is a retinoic acid receptor agonist that is selective for RARalpha (Kd = 62 nM, AC50 = 1.46 nM) compared to RARbeta (Kd = 280 nM, AC50 = 6.87 nM) and RARgamma (Kd = 816 nM, AC50 = 148.7 nM). It demonstrates greater specific binding to RARalpha compared to retinoic acid (Cay-11017), which exhibits little...
Keywords: | Amnolake, NSC 608000, Retinobenzoic Acid, Tamibarotene,... |
Application: | Retinoic acid receptor alpha agonist |
CAS | 94497-51-5 |
MW: | 351.4 D |
From 109.00€
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