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1,4-DPCA
1,4-DPCA

Item number: Cay71220-10

The pro-angiogenic factor HIF-1alpha is targeted for destruction in non-hypoxic environments by the hydroxylation of a specific proline residue, P564, by the oxygen-sensing enzyme HIF-alpha prolyl hydroxylase (HIF-PH). Inhibitors of prolyl 4-hydroxylase are potentially useful in controlling excess collagen...
Keywords: 1,4-dihydrophenonthrolin-4-one-3-Carboxylic acid, 4,4alpha-dihydro-4-oxo-1,10-phenanthroline-3-carboxylic acid
Application: Prolyl 4-hydroxylase inhibitor
CAS 331830-20-7
MW: 240.2 D
From 66.00€ *
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2,4-DPD
2,4-DPD

Item number: Cay71200-10

The pro-angiogenic factor HIF-1alpha is targeted for destruction in normoxic environments by the hydroxylation of a specific proline residue, P564, by the oxygen-sensing enzyme HIF-alpha prolyl hydroxylase (HIF-PH). 2,4-DPD is a cell permeable, competitive inhibitor of HIF-PH. 2,4-DPD inhibits the hydroxylation of...
Keywords: 2,4-Diethylpyridine dicarboxylate, 2,4-pyridinedicarboxylic acid, diethyl ester
Application: HIF-PH inhibitor
CAS 41438-38-4
MW: 223.2 D
From 26.00€ *
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