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Item number: Cay70970-25

U-0126 is a MEK inhibitor with IC50 values of 72 nM and 58 nM for MEK1 and MEK2, respectively. It is noncompetitive with respect adenosine triphosphate (ATP) and its phosphorylation target ERK and it shows little to no inhibition against a number of other kinases including PKC, Ab1, Raf, MEKK, ERK, JNK, MKK-3,...

Keywords:	2,3-bis[amino[(2-aminophenyl)thio]methylene]-butanedinitrile
Application:	MEK inhibitor
CAS	109511-58-2
MW:	380.5 D

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