2 products were found matching "Cay70770"!

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Item number: Cay70770-50

BAY u9773 is a cysteinyl leukotriene 1 (CysLT1) and CysLT2 receptor antagonist. It inhibits contractions induced by leukotriene D4 (LTD4, Cay-20310) or LTC4 (Cay-20210) in isolated guinea pig trachea, rat lung, ferret spleen, and sheep bronchus (pA2s = 6.8-7.4). BAY u9773 (0.1 mg/kg) suppresses airway...

Keywords:	4-[[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraenyl]thio]-benzoic acid
Application:	CysLT1 receptor antagonist
CAS	154978-38-8
MW:	472.6 D

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Bromoenol lactone

Item number: Cay70700-5

BEL is a selective, potent, irreversible, mechanism-based inhibitor of myocardial cytosolic calcium-independent phospholipase A2 (iPLA2) with a Ki value of 180 nM. BEL also inhibits macrophage iPLA2 in a concentration-dependent manner with an IC50 value of 60 nM and is an effective enzyme-activated irreversible...

Keywords:	BEL, Haloenol lactone, HELSS, 6E-(bromomethylene)tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one
Application:	iPLA2 inhibitor
CAS	88070-98-8
MW:	317.2 D

From 161.00€ *

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