- Search results for Cay70730-%25
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4 products were found matching "Cay70730-%25"!
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Item number: Cay70735-25
The peroxisome proliferator-activated receptor-gamma (PPARgamma) is the nuclear receptor responsible for transducing the therapeutic activity of the thiazolidinediones (TZDs), a group of structurally related synthetic agonists with antidiabetic actions in vivo. Rosiglitazone (BRL49653) is a prototypical TZD and has...
Keywords: | Isaglitazone, Netoglitazone, RWJ 241947, 5-[[6-[(2-fluorophenyl)methoxy]-2-naphthalenyl]methyl]-2,4-thiazolidinedione |
Application: | Peroxisome proliferator-activated receptor (PPAR) gamma modulator |
CAS | 161600-01-7 |
MW: | 381.4 D |
From 60.00€
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Item number: Cay70790-25
PPARgamma is a ligand-activated transcription factor involved in the regulation of lipid homeostasis and may function as a master regulator of adipogenesis. Ligands for PPARgamma include antidiabetic drugs of the thiazolidinedione structural class, 15-deoxy-Delta12,14-prostaglandin J2 (Cay-18570), and NSAIDS. BADGE...
Keywords: | Bisphenol A diglycidyl ether, 2,2'-[(1-methylethylidene)bis(4,1-phenyleneoxymethylene)]bis-oxirane |
Application: | PPARgamma agonist |
CAS | 1675-54-3 |
MW: | 340.4 D |
From 23.00€
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Item number: Cay70740-25
U-73122 is an inhibitor of PLC-dependent processes, however, the mechanism of action remains unclear. The IC50 values for inhibition of platelet aggregation induced by collagen or thrombin are 0.6 and 5 µM, respectively. It also exhibits inhibitory activity against HIV-1 integrase with an IC50 value of 7 µM.Formal...
Keywords: | 1-[6-[[(17beta)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H-pyrrole-2,5-dione |
Application: | Lipid signaling studies |
CAS | 112648-68-7 |
MW: | 464.6 D |
From 28.00€
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Item number: Cay70770-25
BAY u9773 is a cysteinyl leukotriene 1 (CysLT1) and CysLT2 receptor antagonist. It inhibits contractions induced by leukotriene D4 (LTD4, Cay-20310) or LTC4 (Cay-20210) in isolated guinea pig trachea, rat lung, ferret spleen, and sheep bronchus (pA2s = 6.8-7.4). BAY u9773 (0.1 mg/kg) suppresses airway...
Keywords: | 4-[[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraenyl]thio]-benzoic acid |
Application: | CysLT1 receptor antagonist |
CAS | 154978-38-8 |
MW: | 472.6 D |
From 86.00€
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