2 products were found matching "Cay70730"!

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Item number: Cay70730-10

Wy 14643 is an agonist of peroxisome proliferator-activated receptor alpha (PPARalpha). It selectively transactivates PPARalpha over PPARgamma in a reporter assay using CV-1 mouse fibroblasts when used at a concentration of 100 µM. Wy 14643 (2 mg/kg) decreases distal colon protein levels of IFN-gamma, TNF-alpha,...

Keywords:	Pirinixic Acid, [[4-chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl]thio]-acetic acid
Application:	PPAR activator
CAS	50892-23-4
MW:	323.8 D

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MCC-555

Item number: Cay70735-10

The peroxisome proliferator-activated receptor-gamma (PPARgamma) is the nuclear receptor responsible for transducing the therapeutic activity of the thiazolidinediones (TZDs), a group of structurally related synthetic agonists with antidiabetic actions in vivo. Rosiglitazone (BRL49653) is a prototypical TZD and has...

Keywords:	Isaglitazone, Netoglitazone, RWJ 241947, 5-[[6-[(2-fluorophenyl)methoxy]-2-naphthalenyl]methyl]-2,4-thiazolidinedione
Application:	Peroxisome proliferator-activated receptor (PPAR) gamma modulator
CAS	161600-01-7
MW:	381.4 D

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