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XD14
XD14

Item number: Cay30740-25

XD14 is a bromodomain-containing protein (BRD) inhibitor. It binds to BRD2, -3, and -4 (Kds = 170, 380, and 160 nM) and inhibits the growth of HL-60 cells (GI50 = ~20 µM). XD14 (10 µM) also inhibits the growth of SR, K562, and MOLT-4 leukemia cells, as well as T47D breast, UO-31 renal, IGROV-1 ovarian, and KM12...
Keywords: 4-acetyl-N-[5-[(diethylamino)sulfonyl]-2-hydroxyphenyl]-3-ethyl-5-methyl-1H-pyrrole-2-carboxamide
Application: BRD inhibitor
CAS 1370888-71-3
MW: 421.5 D
From 158.00€ *
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Furegrelate (sodium salt)
Furegrelate (sodium salt)

Item number: Cay70540-5

Furegrelate is a potent inhibitor of thromboxane synthase with little effect on other enzymes essential for arachidonate metabolism. The IC50 value is 15 nM for human platelet microsomal thromboxane synthase.Formal Name: 5-(3-pyridinylmethyl)-2-benzofurancarboxylic acid, sodium salt. CAS Number: 85666-17-7....
Keywords: U-63557A, 5-(3-pyridinylmethyl)-2-benzofurancarboxylic acid, sodium salt
Application: Thromboxane synthase inhibitor
CAS 85666-17-7
MW: 275.2 D
From 77.00€ *
Review