9 products were found matching "Cay70260"!

Aspirin is a non-steroidal anti-inflammatory drug (NSAID) and a covalent inhibitor of COX-1 and COX-2 (IC50s = 4.45 and 13.88 µM, respectively, for the human enzymes). It is also an inhibitor of hematopoietic prostaglandin D synthase (H-PGDS, IC50 = 750 µM for the ovine enzyme). Aspirin (6 µg/ml) inhibits...

Alanine Transaminase (ALT), also known as alanine aminotransferase (ALAT) or serum glutamic pyruvic transaminase (sGPT), is a homodimeric cytoplasmic pyridoxal phosphate-dependent enzyme involved in cellular nitrogen metabolism, amino acid metabolism, and liver gluconeogenesis. ALT mediates conversion of major...

Cayman's Ethanol Colorimetric Assay Kit provides a colorimetric-based method for measuring ethanol in alcoholic beverages, vinegars, and synthetic media for yeast culture. In the assay, an alcohol oxidase (AOX) oxidizes ethanol, producing acetaldehyde and hydrogen peroxide (H2O2). The Ethanol Assay Probe is oxidized...

Cayman's LipidLaunch(TM) LNP Apparent pKa Assay Kit (TNS Method) provides a robust and easy-to-use platform for testing the apparent/global pKa of formulated LNPs. The assay uses a fluorogenic probe, 6-(p-toluidino)-2-naphthalenesulfonic acid sodium salt (TNS). This probe fluoresces in association with positively...

Cayman's TXAS Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human TXAS. The assay uses a TAMRA-conjugated TXAS-specific probe suitable for fluorescence polarization (FP)-based screening of TXAS inhibitors. Inhibitors of TXAS displace the fluorescent...

Cayman's LipidLaunch(TM) SM-102 LNP Kit (Loadable) provides cargo-ready, empty, lyophilized SM-102 LNPs specially formulated for in vitro RNA transfection. Following resuspension, these LNPs are capable of rapid encapsulation of RNA, without the need for incubation steps, enabling subsequent delivery to target...

5-Aminosalicylic acid (5-ASA) is a non-steroidal anti-inflammatory drug (NSAID) and an active metabolite of sulfasalazine (Cay-15025), balsalazide (Cay-18680), and olsalazine (Cay-23661). It is formed from these prodrugs by bacterial azoreductases in the intestinal lumen. 5-ASA selectively inhibits COX-2 over COX-1...

O-Acetyl Salicylhydroxamic Acid (O-ASHA) is an irreversible, non-selective inhibitor of COX-1 and COX-2. Aspirin is the best-studied example of an irreversible COX inhibitor, acting via the acetylation of the active site serine residue 529 in human COX-1. O-ASHA inhibits ovine COX-1 in a time-dependent, irreversible...

Cayman's Extracellular Vesicle Isolation Kit (Tissue Culture) provides a simple, quick, and convenient precipitation-based method for isolating extracellular vesicles from tissue culture media. The volume of Extracellular Vesicle Isolation Reagent provided is sufficient for processing up to 40 ml of media. Also...