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SIRT2 Direct Fluorescent Screening Assay Kit
SIRT2 Direct Fluorescent Screening Assay Kit

Item number: Cay700280-96

The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) that catalyze a reaction coupling lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose. Cayman's SIRT2 Direct Fluorescent Screening Assay provides a fluorescence-based method for...
Keywords: SIRT2, SIR2L, EC=3.5.1.-, SIR2-like protein 2, NAD-dependent deacetylase sirtuin-2
Application: SIRT2 assays, inhibitor screening, activator screening
Species reactivity: human
467.00€ *
Review
(±)-Ibuprofen
(±)-Ibuprofen

Item number: Cay70280-1000

(±)-Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) and non-selective COX inhibitor (IC50s = 2.6 and 1.3 µM for human recombinant COX-1 and COX-2, respectively). In vivo, (±)-ibuprofen inhibits late-phase formalin-induced paw licking in mice (ED50 = 6.1 mg/kg). It also inhibits acetic acid-induced...
Keywords: DL-Ibuprofen, NSC 256857, U-18753, (±)-alpha-methyl-4-(2-methylpropyl)-benzeneacetic acid
Application: COX inhibitor
CAS 15687-27-1
MW: 206.3 D
From 20.00€ *
Review