8 products were found matching "Cay582251"!

5(6)-Carboxyfluorescein diacetate (CFDA) is a fluorescent probe used to stain cells with intact membranes for analysis in applications such as flow cytometry or fluorescence microscopy. It has relatively slow cellular efflux with a half-life of ~94 minutes and displays fluorescence with excitation/emission maxima of...

While testosterone is the primary androgenic male steroid found in mammals, 11-keto testosterone (11-KT) is a second key androgenic steroid found in fish. It occurs in males together with testosterone in amounts which vary from less than 1 ng/ml to as much as 50-100 ng/ml, depending on the species and the stage of...

Carfilzomib-d8 is intended for use as an internal standard for the quantification of carfilzomib (Cay-17554) by GC- or LC-MS. Carfilzomib is an irreversible proteosome inhibitor classified as a peptide epoxyketone. It targets the chymotrypsin-like beta5 subunit of the constitutive 20S proteasome (IC50 = 5.2 nM) and...

2-Methoxyestradiol (2-ME2) is a natural metabolite of estradiol produced by CYP450-dependant hydroxylation followed by catechol-O-methyltransferase-catalyzed O-methylation. Deficiency in catechol-O-methyltransferase is associated with pre-eclampsia. Therefore, 2-ME2 may be utilized as a plasma and urinary diagnostic...

Estriol, a metabolite of 17beta-estradiol and a major estrogen produced during pregnancy, has historically been used as an indicator of fetal well-being. In the final weeks before parturition, estriol levels increase significantly. In a longitudinal study in healthy pregnant women, total plasma estriol levels...

9(S)-Hexahydrocannabivarin (Cay-38225) is an analytical reference standard that is structurally similar to known phytocannabinoids. This product is intended for research and forensic applications.Formal Name: (6aR,9S,10aR)-6,6,9-trimethyl-3-propyl-6a,7,8,9,10,10a-hexahydro-6H-benzo[c]chromen-1-ol. Molecular Formula:...

9c(i472) is an inhibitor of 15-lipoxygenase-1 (15-LO-1, IC50 = 0.19 µM). It decreases LPS- and IFN-gamma-induced NF-?B activity in RAW-Blue(TM) cells when used at concentrations of 0.2, 1, and 5 µM. 9c(i472) reduces LPS- and IFN-gamma-induced increases in Nos2 expression and lipid peroxidation in RAW 264.7 cells...

Gramicidin is a polypeptide antibiotic mixture of gramicidin A (Cay-26384), gramicidin B, and gramicidin C originally isolated from B. brevis. It is also a component of the antibiotic tyrothricin (Cay-22177). Gramicidin is active against the Gram-positive bacterium S. aureus but not Gram-negative E. coli. It also...