- Search results for Cay582121.1
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7 products were found matching "Cay582121.1"!
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Item number: Cay18212-500
13,14-dehydro-15-cyclohexyl Carbaprostacyclin is a chemically stable analog of PGI2. It inhibits the ADP-induced aggregation of human platelets with an ED50 of about 40 nM in PRP and 77 nM in washed platelets, which is comparable to the potency of carbaprostacyclin.Formal Name:...
Keywords: | 6,9alpha-methylene-11alpha-hydroxy-15,16,17,18,19,20-hexanor-14-(1-hydroxycyclohexyl)-prost-5E-en-13-yn-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 145375-81-1 |
MW: | 346.5 D |
From 84.00€
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Item number: Cay51212-100
5,6-DiHET lactone is a lactonized form of 5,6-EET and 5,6-DiHET. In solution, 5(6)-EET degrades into 5(6)-DiHET and 5(6)-delta-lactone, which can be converted to 5(6)-DiHET and quantified by GC-MS. 5,6-DiHET potently induces vasodilation of isolated canine coronary arterioles, with 41 and 100% inhibition occurring...
Keywords: | (±)5,6-DiHETrE lactone, tetrahydro-6-[(3Z,6Z,9Z)-1-hydroxy-3,6,9-pentadecatrien-1-yl]-2H-pyran-2-one |
Application: | Bioactive lipid studies |
CAS | 213126-92-2 |
MW: | 320.5 D |
From 123.00€
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Item number: Cay28121-1
Leucomycin A13 is a macrolide antibiotic and a component of the leucomycin complex originally isolated from S. kitasatoensis. It is active against B. subtilis, S. aureus, M. luteus, and E. coli with MIC values of 0.16, 0.16, 0.08 and >10 µg/ml, respectively. It binds to ribosomes with an IC50 value of 1.2 µM in a...
Keywords: | Kitasamycin A13, 4B-hexanoate leucomycin V |
Application: | Macrolide antibiotic |
CAS | 78897-52-6 |
MW: | 800 D |
From 324.00€
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Item number: Cay28215-1
CL2-SN-38 is a cleavable linker-based antibody-drug conjugate (ADC) containing the topoisomerase I inhibitor SN-38 (Cay-15632) and a maleimidocaproyl linker. CL2-SN-38 has been linked to tumor-selective human monoclonal antibodies, such as anti-CEACAM5 (hMN-14) to target SN-38 to tumor sites and improve its...
Keywords: | N-[32-[4-[[[[4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]cyclohexyl]carbonyl]amino]methyl]-1H-1,2,3-triazol-1-yl]-1,5-... |
MW: | 1627.8 D |
From 43.00€
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Item number: Cay28212-1
(Z-IETD)2-Rh 110 is a fluorogenic substrate for caspase-8. Upon enzymatic cleavage by caspase-8, rhodamine 110 (Cay-19061) is released and its fluorescence can be used to quantify caspase-8 activity. Rhodamine 110 displays excitation/emission maxima of 496/520 nm, respectively.Formal Name:...
Keywords: | (Z-Ile-Glu-Thr-Asp)2-R110, Rhodamine 110 bis-(N-CBZ-IETD)2,... |
Application: | Fluorogenic caspase-8 substrate |
MW: | 1515.5 D |
163.00€
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Item number: Cay25821-25
Pyridaben is a METI acaricide that inhibits mitochondrial electron transport at complex I (METI, Ki = 0.36 nmol/mg protein in rat brain mitochondria). It is active against a variety of mites, inducing 100% mortality of C. malaccensis, D. farina, and T. putrescentia when administered via filter paper contact at doses...
Keywords: | BAS 300, Damanlin, GWN 1715, NC 129,... |
Application: | Acaricide, mitochondrial electron transport at complex I inhibitor |
CAS | 96489-71-3 |
MW: | 364.9 D |
From 35.00€
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Item number: Cay35821-25
Thiocolchicoside is a GABAA receptor antagonist. It inhibits GABAA receptor-mediated currents in Purkinje cells isolated from rat cerebellum (IC50 = 0.15 µM). It binds strychnine-sensitive glycine receptors in isolated rat spinal cord (IC50 = 1.58 µM). Thiocolchicoside inhibits cell growth in a panel of cancer cell...
Keywords: | NSC 147755, R-271,... |
Application: | GABAA receptor antagonist |
CAS | 602-41-5 |
MW: | 563.6 D |
From 90.00€
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